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Cancer Stem Cells

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Contents



Astrocytomas


Ma YH, Mentlein R, Knerlich F, Kruse ML, Mehdorn HM, Held-Feindt J.
Expression of stem cell markers in human astrocytomas of different WHO grades
J Neurooncol. 2007 Jul 5; [Epub ahead of print]
Abstract

Nader Sanai, Anthony D. Tramontin, Alfredo Quiñones-Hinojosa, Nicholas M. Barbaro, Nalin Gupta, Sandeep Kunwar, Michael T. Lawton, Michael W. McDermott, Andrei T. Parsa, José Manuel-García Verdugo, Mitchel S. Berger, Arturo Alvarez-Buylla
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
Nature 427, 740 - 744 (19 February 2004); doi:10.1038/nature02301
Abstract

Yang Y, Qiu Y, Ren W, Gong J, Chen F
An identification of stem cell-resembling gene expression profiles in high-grade astrocytomas
Mol Carcinog. 2008 Apr 7; [Epub ahead of print]
 Abstract


Basic Science


Itzhak Avital, Andre L. Moreira, David S. Klimstra, Margaret Leversha, Esperanza B. Papadopoulos, Murray Brennan, Robert J. Downey
Donor-Derived Human Bone Marrow Cells Contribute to Solid Organ Cancers Developing After Bone Marrow Transplantation
Stem Cells Nov 2007; 25: 2903 - 2909 ; doi:10.1634/stemcells.2007-0409
Abstract

Blagosklonny MV.
Cancer stem cell and cancer stemloids: from biology to therapy
Cancer Biol Ther. 2007 Nov;6(11):1-7
 Abstract

Cheshier SH, Kalani MY, Lim M, Ailles L, Huhn SL, Weissman IL
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells
Neurosurgery. 2009 Aug;65(2):237-49
  Abstract |   Full text |   Reprint

Dirks PB
Brain tumor stem cells: The cancer stem cell hypothesis writ large
Mol Oncol. 2010 Aug 10;. [Epub ahead of print]
  Abstract

Kaisorn Chaichana, Grettel Zamora-Berridi, Joaquin Camara-Quintana, Alfredo Quiñones-Hinojosa
Neurosphere Assays: Growth Factors and Hormone Differences in Tumor and Nontumor Studies

Stem Cells Vol. 24 No. 12 December 2006, pp. 2851 -2857. First published online August 31, 2006
Abstract | Full Text | Reprint

Michael F. Clarke, John E. Dick, Peter B. Dirks, Connie J. Eaves, Catriona H.M. Jamieson, D. Leanne Jones, Jane Visvader, Irving L. Weissman and Geoffrey M. Wahl
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
Cancer Res 2006;66:9339–44; October 1 2006, Volume 66, CNO 19
Abstract | Full text | Reprint

Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
Curr Biol. 2007 Jan 23;17(2):165-72. Epub 2006 Dec 28. Erratum in: Curr Biol. 2007 Jan 23;17(2):192
 Abstract |  Full text |  Reprint

Michael Dean
CANCER STEM CELLS: Redefining the Paradigm of Cancer Treatment Strategies
Mol. Interv., June 1, 2006; 6(3): 140 - 148
Abstract | Full Text | Reprint

R. Ganguly and I. K. Puri
Mathematical model for the cancer stem cell hypothesis
Cell Proliferation, Volume 39, CNO 1, Page 3  - February 2006
Abstract | Full Text | Reprint

Gennadi V. Glinsky, Olga Berezovska and Anna B. Glinskii
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
J. Clin. Invest. 115:1503-1521 (1 June 2005)
Abstract | Full Text | Reprint

Germano I, Swiss V, Casaccia P
Primary brain tumors, neural stem cell, and brain tumor cancer cells: Where is the link?
Neuropharmacology. 2009 Dec 31;. [Epub ahead of print]
  Abstract

Wei Guo, Joseph L. Lasky, III and Hong Wu
Cancer Stem Cells
Pediatric Research 59:59R-64R (April 1, 2006)
Abstract | Full Text | Reprint

Heffron CC, Gallagher MF, Guenther S, Sherlock J, Henfrey R, Martin C, Sheils O, O'Leary JJ.
Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model.
Anticancer Res. 2007 May-Jun;27(3A):1319-24.
Abstract

Hellman S, Botnick L, Mauch P
Stem-Cell Biology and Cancer Therapy: The More Things Change...
J Clin Oncol. 2008 Feb 20;26(6):821-822
 Abstract |  Full text |  Reprint

S Hellman, U Reincke, L Botnick, and P Mauch
Functional organization of the hematopoietic stem cell compartment: implications for cancer and its therapy
JCO Apr 1 1983: 277-284
 Abstract |  Reprint

Daniella Herszfeld, Ernst Wolvetang, Emma Langton-Bunker, Tung-Liang Chung, Adam A Filipczyk, Souheir Houssami, Pegah Jamshidi, Karen Koh, Andrew L Laslett, Anna Michalska, Linh Nguyen, Benjamin E Reubinoff, Irene Tellis, Jonathan M Auerbach, Carol J Ording, Leendert H J Looijenga & Martin F Pera
CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells
Nature Biotechnology, Advance online publication, Published online: 26 February 2006; DOI: doi:10.1038/nbt1197
  Abstract |   News

Hide T, Takezaki T, Nakamura H, Kuratsu J, Kondo T
Brain tumor stem cells as research and treatment targets
Brain Tumor Pathol. 2008 Nov ;25(2):67-72. Published online: 6 November 2008
  Abstract

Richard P. Hill, Roberto Perris
"Destemming" Cancer Stem Cells
JNCI 2007 99(19):1435-1440; doi:10.1093/jnci/djm136. Published online on September 25, 2007
 Abstract

Kang MK, Her BI, Ko MH, Kim CH, Cha SH, Kang SK
Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma
BMC Neurosci. 2008 Jan 30;9(1):15
Abstract | Reprint

Kondo T
Stem cell-like cancer cells in cancer cell lines
Cancer Biomark. 2007;3(4-5):245-50. Published Online: 28 September 2007
 Abstract

Nathan D. Price, Greg Foltz, Anup Madan, Leroy Hood and Qiang Tian
Systems Biology and Cancer Stem Cells
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Nov-2007; doi: 10.1111/j.1582-4934.2007.00151.x
 Abstract |  Reprint

Qu K, Ortoleva P
Understanding stem cell differentiation through self-organization theory
J Theor Biol. 2007 Oct 23;. [Epub ahead of print]
Abstract

Shipitsin M, Polyak K
The cancer stem cell hypothesis: in search of definitions, markers, and relevance
Lab Invest. 2008 Mar 31;. [Epub ahead of print]
 Abstract

Soltysova A, Altanerova V, Altaner C
Cancer stem cells
Neoplasma. 2005;52(6):435-40
 Abstract

Matilde Todaro, Mileidys Perez Alea, Anna B. Di Stefano, Patrizia Cammareri, Louis Vermeulen, Flora Iovino, Claudio Tripodo, Antonio Russo, Gaspare Gulotta, Jan Paul Medema and Giorgio Stassi
Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4
Cell Stem Cell. 2007 Oct 10;1(4):389-402
 Abstract

Siebzehnrubl FA, Reynolds BA, Vescovi A, Steindler DA, Deleyrolle LP.
The origins of glioma: E Pluribus Unum?
Glia. 2011 Feb 23;. [Epub ahead of print]
  Abstract |   Related articles

Timothy C. Wang
Bone Marrow-Derived Stem Cells: Implications for Cancer Prevention
AACR Meeting Abstracts, Nov 2006; 2006: PL03-02
Abstract

Wang Z, Li Y, Banerjee S, Sarkar FH
Emerging role of Notch in stem cells and cancer
Cancer Lett. 2009 Jun 28;279(1):8-12. Epub 2008 Nov 20
  Abstract

Wang Y, Armstrong SA
Cancer: inappropriate expression of stem cell programs?
Cell Stem Cell. 2008 Apr 9;2(4):297-9
 Abstract

Xu F, Zhu JH
Stem cells tropism for malignant gliomas
Neurosci Bull. 2007 Nov;23(6):363-9
  Abstract

Wicha , Liu Suling and Dontu
Cancer Stem Cells: An Old Idea—A Paradigm Shift
Cancer Research 66, 1883-1890, February 15, 2006
Abstract | Full Text | Reprint


Brain Tumors


Ayuso-Sacido A, Graham C, Greenfield JP, Boockvar JA
The duality of epidermal growth factor receptor (EGFR) signaling and neural stem cell phenotype: cell enhancer or cell transformer?
Curr Stem Cell Res Ther. 2006 Sep;1(3):387-94
Abstract

Christopher Calabrese, Helen Poppleton, Mehmet Kocak, Twala L. Hogg, Christine Fuller, Blair Hamner, Eun Young Oh, M. Waleed Gaber, David Finklestein, Meredith Allen, Adrian Frank, Ildar T. Bayazitov, Stanislav S. Zakharenko, Amar Gajjar, Andrew Davidoff, and Richard J. Gilbertson
A Perivascular Niche for Brain Tumor Stem Cells
Cancer Cell. 2007 Jan;11(1):69-82
Abstract | Full text | Reprint | Supplemental Data

Caussinus E, Hirth F
Asymmetric stem cell division in development and cancer
Prog Mol Subcell Biol. 2007;45:205-25.
Abstract

Clark PA, Treisman DM, Ebben J, Kuo JS.
Developmental signaling pathways in brain tumor-derived stem-like cells.
Dev Dyn. 2007 Nov 14;236(12):3297-3308 [Epub ahead of print]
Full Text | Reprint

Deng YW, Fang JS, Li MC, Chen FH, Zhou XY, Wu J, Zhou RH, Fang F, Chen C, Lu M, Zeng FY
Correlation research between cancer stem cells and the pathological grades of neuroepithelial tumors
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Feb;31(1):45-51
 Abstract

Dirks PB
Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells
Philos Trans R Soc Lond B Biol Sci. 2008 Jan 12;363(1489):139-52
  Abstract |   Full text |   Reprint

Dirks PB
Brain tumor stem cells
Biol Blood Marrow Transplant. 2005 Feb;11(2 Suppl 2):12-3
  Abstract |   Full text |   Reprint

Dirks PB
Brain tumor stem cells: bringing order to the chaos of brain cancer
J Clin Oncol. 2008 Jun 10;26(17):2916-24
  Abstract

Anna Erlandsson, Karin Brännvall, Sigrun Gustafsdottir, Bengt Westermark and Karin Forsberg-Nilsson
Autocrine/Paracrine Platelet-Derived Growth Factor Regulates Proliferation of Neural Progenitor Cells
Cancer Research 66, 8042-8048, August 15, 2006
Abstract | Full Text | Reprint

Fang JS, Deng YW, Li MC, Chen FH, Wang YJ, Lu M, Fang F, Wu J, Yang ZY, Zhou XY, Wang F, Chen C
Isolation and identification of brain tumor stem cells from human brain neuroepithelial tumors
Zhonghua Yi Xue Za Zhi. 2007 Jan 30;87(5):298-303
 Abstract

Fomchenko EI, Holland EC
Stem cells and brain cancer
Exp Cell Res. 2005 Jun 10;306(2):323-9. Epub 2005 Apr 14
 Abstract

Galli R, Gritti A, Vescovi AL.
Adult Neural Stem Cells
Methods Mol Biol. 2008 Feb 5;438:67-84
 Abstract

Jandial R, U H, Levy ML, Snyder EY.
Brain tumor stem cells and the tumor microenvironmen
Neurosurg Focus. 2008 Mar;24(3-4):E27
  Abstract |   Full text |   Reprint

Harley Kornblum, Houman Hemmati, Ichiro Nakano, Michael Masterman-Smith, Marianne Bronner-Fraser, Jorge Lazareff, Stan Nelson, Linda Liau, Paul Mischel, Daniel H. Geschwind
Neural stem cells, brain tumors, and brain tumor stem cells
AACR 96th Annual Meeting, April 16-20, 2005, Anaheim/Orange County, CA
Proc Amer Assoc Cancer Res 2005;46:[SY23]

Abstract

Liu W, Shen G, Shi Z, Shen F, Zheng X, Wen L, Yang X
Brain tumour stem cells and neural stem cells: still explored by the same approach?
J Int Med Res. 2008 Sep-Oct;36(5):890-5
  Abstract |   Reprint

Ichiro Nakano and Harley I. Kornblum
Brain Tumor Stem Cells
Pediatric Research 59:54R-58R (April 1, 2006)
Abstract | Full Text | Reprint

Nicolis SK
Cancer stem cells and "stemness" genes in neuro-oncology
Neurobiol Dis. 2007 Feb;25(2):217-29. Epub 2006 Dec 1
 Abstract

Ji XY, Huang Q, Dong J, Zhu YD, Wang AD, Lan Q
Characteristics of morphology, differentiation related marker, and proliferation dynamics of differentiated brain tumor stem cells in vitro
Zhonghua Yi Xue Za Zhi. 2006 Jun 20;86(23):1604-9
 Abstract

Oliver TG, Wechsler-Reya RJ
Getting at the root and stem of brain tumors
Neuron. 2004 Jun 23;42(6):885-8
Abstract | Full Text | Reprint

Francesca Pentimalli
Cancer Stem Cells: BMPs on the Brain
Nature Reviews Cancer 7, 4 (January 2007) | doi:10.1038/nrc2065
 Full text |  Reprint

Cosima V. Pfenninger, Teona Roschupkina, Falk Hertwig, Denise Kottwitz, Elisabet Englund, Johan Bengzon, Sten Eirik Jacobsen, and Ulrike A. Nuber
CD133 Is Not Present on Neurogenic Astrocytes in the Adult Subventricular Zone, but on Embryonic Neural Stem Cells, Ependymal Cells, and Glioblastoma Cells
Cancer Research 67, 5727-5736, June 15, 2007. doi: 10.1158/0008-5472.CAN-07-0183
Abstract | Full text | Reprint

Piccirillo SG, Binda E, Fiocco R, Vescovi AL, Shah K
Brain cancer stem cells
J Mol Med. 2009 Nov;87(11):1087-95. Epub 2009 Sep 29
  Abstract |   Full text |   Reprint

Rich JN, Eyler CE
Cancer Stem Cells in Brain Tumor Biology
Cold Spring Harb Symp Quant Biol. 2009 Mar 27; [Epub ahead of print]
  Abstract

Rubio D, Garcia S, Paz MF, De la Cueva T, Lopez-Fernandez LA, Lloyd AC, Garcia-Castro J, Bernad A  
Molecular Characterization of Spontaneous Mesenchymal Stem Cell Transformation
PLoS ONE. 2008; 3(1): e1398. Published online 2008 January 2. doi: 10.1371/journal.pone.0001398
Abstract | Full text | Reprint

Sanai N, Berger MS.
Biology of brain tumor stem cells
Neurosurg Focus. 2008 Mar;24(3-4):E26
 Abstract |  Full text |  Reprint

Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke, Jeremy A. Squire, Jane Bayani, Takuichiro Hide, R. Mark Henkelman, Michael D. Cusimano & Peter B. Dirks
Identification of human brain tumour initiating cells
Nature 432, 396 - 401 (18 November 2004)
Abstract | Reprint

Singh SK, Clarke ID, Hide T, Dirks PB
Cancer stem cells in nervous system tumors
Oncogene. 2004 Sep 20;23(43):7267-73
  Abstract |   Full Text |   Reprint

Sheila K. Singh, Ian D. Clarke, Mizuhiko Terasaki, Victoria E. Bonn, Cynthia Hawkins, Jeremy Squire and Peter B. Dirks
Identification of a Cancer Stem Cell in Human Brain Tumors
Cancer Research 63, 5821-5828, September 15, 2003
Abstract | Full Text | Reprint

Veeravagu A, Bababeygy SR, Kalani MS, Hou L, Tse V
The Cancer Stem Cell-Vascular Niche Complex in Brain Tumor Formation
Stem Cells Dev. 2008 Apr 22;. [Epub ahead of print]
 Abstract

Angelo L. Vescovi, Rossella Galli and Brent A. Reynolds
Brain tumour stem cells
Nature Reviews Cancer 6, 425-436 (June 2006)
Abstract |   Full text |   Reprint

Darius Widera, Aljoscha Kaus, Christian Kaltschmidt and Barbara Kaltschmidt
Neural stem cells, inflammation and NF-κB: basic principle of maintenance and repair or origin of brain tumours?
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Dec-2007, doi: 10.1111/j.1582-4934.2007.00208.x
 Abstract |  Reprint

Xie Z
Brain Tumor Stem Cells
Neurochem Res. 2009 Oct 24. [Epub ahead of print]
  Abstract

Xie Z, Chin LS.
Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells
Neurosurg Focus. 2008 Mar;24(3-4):E25
 Abstract |  Full text |  Reprint

Yao Y, Tang X, Li S, Mao Y, Zhou L
Brain tumor stem cells: view from cell proliferation
Surg Neurol. 2009 Mar;71(3):274-9
  Abstract

Yao Y, Tao R, Wang X, Wang Y, Mao Y, Zhou L
B7-H1 is correlated with the malignancy grade of gliomas but it is not the privilege of tumor stem-like cells
Neuro Oncol. 2009 Mar 5;. [Epub ahead of print]
  Abstract

Zhang QB, Ji XY, Huang Q, Dong J, Zhu YD, Lan Q
Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells
Cell Res. 2006 Dec;16(12):909-15
 Abstract |  Full text |  Reprint


CSC Hypothesis: Evaluation


Richard P. Hill
Identifying Cancer Stem Cells in Solid Tumors: Case Not Proven
Cancer Research 66, 1891-1896, February 15, 2006
  Abstract |   Full Text |   Reprint

Jin F, Zhao L, Zhao HY, Guo SG, Feng J, Jiang XB, Zhang SL, Wei YJ, Fu R, Zhao JS
Paradoxical expression of anti-apoptotic and MRP genes on cancer stem-like cell isolated from TJ905 glioblastoma multiforme cell line
Cancer Invest. 2008 May;26(4):338-43
  Abstract |   Related articles

Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A. 
Tumor growth need not be driven by rare cancer stem cells.
Science. 2007 Jul 20;317(5836):337.
  Abstract |   Full text |   Reprint

Yoo MH, Hatfield DL.
The Cancer Stem Cell Theory: Is It Correct?
Mol Cells. 2008 Aug 14;26(5). [Epub ahead of print]
  Abstract |   Reprint

Prestegarden L, Enger PØ.
Cancer stem cells in the central nervous system--a critical review.
Cancer Res. 2010 Nov 1;70(21):8255-8. Epub 2010 Oct 19.
  Abstract |   Reprint |   Related articles


Ependymoma


Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ
Radial glia cells are candidate stem cells of ependymoma
Cancer Cell. 2005 Oct;8(4):323-35. Erratum in: Cancer Cell. 2006 Jan;9(1):70
 Abstract |  Full text |  Reprint


Glioblastoma


Abdouh M, Facchino S, Chatoo W, Balasingam V, Ferreira J, Bernier G.
BMI1 sustains human glioblastoma multiforme stem cell renewal
J Neurosci. 2009 Jul 15;29(28):8884-96
  Abstract

Altaner C
Glioblastoma and stem cells
Neoplasma. 2008;55(5):369-74
 Abstract |  Reprint

Annabi B, Laflamme C, Sina A, Lachambre MP, Béliveau R.
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells
J Neuroinflammation. 2009 Mar 9;6:8
  Abstract |   Full text |   Reprint

Balenci L, Clarke ID, Dirks PB, Assard N, Ducray F, Jouvet A, Belin MF, Honnorat J, Baudier J.
IQGAP1 Protein Specifies Amplifying Cancer Cells in Glioblastoma Multiforme.
Cancer Res. 2006 Sep 15;66(18):9074-82.
Abstract | Full Text | Reprint

G. L. Banna, R. Pallini, L. Ricci-Vitiani, M. Signore, D. Lombardi, M. Martini, G. Maira, D. Giuffrida, L. M. Larocca, and R. De Maria
High prognostic potential of glioblastoma stem cell analysis
ASCO Meeting Abstracts, Jun 2007; 25: 10580
Abstract

Shideng Bao, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hjelmeland, Mark W. Dewhirst, Darell D. Bigner and Jeremy N. Rich
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Nature advance online publication 18 October 2006
Abstract

Shideng Bao, Qiulian Wu, Sith Sathornsumetee, Yueling Hao, Zhizhong Li, Anita B. Hjelmeland, Qing Shi, Roger E. McLendon, Darell D. Bigner and Jeremy N. Rich
Stem Cell–like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor
Cancer Research 66, 7843-7848, August 15, 2006
Abstract | Full Text | Reprint

Dagmar Beier, Peter Hau, Martin Proescholdt, Annette Lohmeier, Jörg Wischhusen, Peter J. Oefner, Ludwig Aigner, Alexander Brawanski, Ulrich Bogdahn, and Christoph P. Beier
CD133+ and CD133 Glioblastoma-Derived Cancer Stem Cells Show Differential Growth Characteristics and Molecular Profiles
Cancer Research 67, 4010-4015, May 1, 2007. doi: 10.1158/0008-5472.CAN-06-4180
Abstract | Reprint

Xiu-wu Bian, Xiao-hong Yao, Yi-fang Ping, Jian-hong Chen, and Ji Ming Wang
Glioblastoma stem cells produce angiogenic factors through activation of chemokine receptor CXCR4
FASEB J. 2007 Mar; 21:lb314
Abstract

Bleau AM, Huse JT, Holland EC
The ABCG2 resistance network of glioblastoma
Cell Cycle. 2009 Sep 15;8(18):2936-44
  Abstract

Charles N, Holland EC.
Brain tumor treatment increases the number of cancer stem-like cells
Expert Rev Neurother. 2009 Oct;9(10):1447-9
  Abstract |   Full text |   Reprint

Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, James CD, VandenBerg SR, Costello JF, Moorefield S, Cowdrey CJ, Prados M, Phillips HS.
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
Cancer Cell. 2010 Apr 13;17(4):362-75
  Abstract

Clément V, Marino D, Cudalbu C, Hamou MF, Mlynarik V, de Tribolet N, Dietrich PY, Gruetter R, Hegi ME, Radovanovic I
Marker-independent identification of glioma-initiating cells
Nat Methods. 2010 Mar;7(3):224-8. Epub 2010 Feb 21
  Abstract

Ernst A, Hofmann S, Ahmadi R, Becker N, Korshunov A, Engel F, Hartmann C, Felsberg J, Sabel M, Peterziel H, Durchdewald M, Hess J, Barbus S, Campos B, Starzinski-Powitz A, Unterberg A, Reifenberger G, Lichter P, Herold-Mende C, Radlwimmer B
Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival
Clin Cancer Res. 2009 Nov 1;15(21):6541-50. Epub 2009 Oct 27
  Abstract

Sabrina Facchino, Mohamed Abdouh and Gilbert Bernier
Brain Cancer Stem Cells: Current Status on Glioblastoma Multiforme.
Cancers 2011, 3(2), 1777-1797. Published: 30 March 2011
  Abstract |   Reprint |   Related articles

Fu J, Liu ZG, Liu XM, Chen FR, Shi HL, Pangjesse CS, Ng HK, Chen ZP
Glioblastoma stem cells resistant to temozolomide-induced autophagy
Chin Med J (Engl). 2009 Jun 5;122(11):1255-9
  Abstract |   Full text |   Reprint

Fukaya R, Ohta S, Yamaguchi M, Fujii H, Kawakami Y, Kawase T, Toda M
Isolation of cancer stem-like cells from a side population of a human glioblastoma cell line, SK-MG-1
Cancer Lett. 2009 Nov 12. [Epub ahead of print]
  Abstract

Gambelli F, Sasdelli F, Manini I, Gambarana C, Oliveri G, Miracco C, Sorrentino V.
Identification of cancer stem cells from human Glioblastomas: growth and differentiation capabilities and CD133/Prominin-1 expression.
Cell Biol Int. 2011 Sep 15;. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Ali Jourabchi Ghods, Dwain Irvin, Gentao Liu, Xiangpeng Yuan, Iman R. Abdulkadir, Patrizia Tunici, Bindu Konda, Sebastian Wachsmann-Hogiu, Keith L. Black, John S. Yu
Spheres Isolated from 9L Gliosarcoma Rat Cell Line Possess Chemoresistant and Aggressive Cancer Stem-Like Cells
Stem Cells Jul 2007; 25: 1645 - 1653 ; doi:10.1634/stemcells.2006-0624
Abstract

Godlewski J, Newton HB, Chiocca EA, Lawler SE.
MicroRNAs and glioblastoma; the stem cell connection
Cell Death Differ. 2009 Jun 12;. [Epub ahead of print]
  Abstract

Huang Z, Cheng L, Guryanova Olga A, Wu Q and Bao S
Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting
Protein & Cell, 2010, Volume 1, Number 7, July 2010, Pages 638-655
  Abstract

Huttner HB, Janich P, Köhrmann M, Jászai J, Siebzehnrubl F, Blümcke I, Suttorp M, Gahr M, Kuhnt D, Nimsky C, Krex D, Schackert G, Löwenbrück K, Reichmann H, Jüttler E, Hacke W, Schellinger PD, Schwab S, Wilsch-Bräuninger M, Marzesco AM, Corbeil D
The Stem Cell Marker Prominin-1/CD133 On Membrane Particles In Human Cerebrospinal Fluid Offers Novel Approaches For Studying CNS Disease
Stem Cells. 2007 Dec 20; [Epub ahead of print]
Abstract

Rossella Galli, Elena Binda, Ugo Orfanelli, Barbara Cipelletti, Angela Gritti, Simona De Vitis, Roberta Fiocco, Chiara Foroni, Francesco Dimeco and Angelo Vescovi
Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma
Cancer Research 64, 7011-7021, October 1, 2004
Abstract | Full Text | Reprint

Christine Glanz, Johan Rebetz, Ylva Stewénius, David Gisselsson, Anna Darabi, Elisabet Englund, Leif G. Salford, Bengt Widegren, Xiaolong Fan
Genetic identification of glioblastoma maintaining cells in a xenograft model
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.2045
Abstract

Caroline Gregorian, Matthias Groszer, Qing Yue, Xin Liu, Hong Wu
The Role of PTEN Tumor Suppressor in Brain Growth and Tumor Development
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.2075
Abstract

Günther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K.
Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
Oncogene. 2007 Nov 26; [Epub ahead of print]
Abstract

Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
Nat Genet. 2000 May;25(1):55-7

Abstract | Full Text | Reprint

Jin F, Li HS, Zhao L, Wei YJ, Zhang H, Guo YJ, Pang R, Jiang XB, Zhao HY.
Expression of anti-apoptotic and multi-drug resistance-associated protein genes in cancer stem cell isolated from TJ905 glioblastoma multiforme cell line
Zhonghua Yi Xue Za Zhi. 2008 Aug 26;88(33):2312-6
  Abstract

Kang MK, Her BI, Ko MH, Kim CH, Cha SH, Kang SK
Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma
BMC Neurosci. 2008 Jan 30;9(1):15
Abstract | Reprint

Kappadakunnel M, Eskin A, Dong J, Nelson SF, Mischel PS, Liau LM, Ngheimphu P, Lai A, Cloughesy TF, Goldin J, Pope WB
Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone
J Neurooncol. 2009 Aug 5. [Epub ahead of print]
  Abstract |   Full text |   Reprint

Kroonen J, Nguyen-Khac MT, Deprez M, Rogister B, Robe P.
Glioblastoma, an example of translational research?
Rev Med Liege. 2008 May-Jun;63(5-6):251-6
 Abstract

Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF
Pten haploinsufficiency accelerates formation of high-grade astrocytomas
Cancer Res. 2008 May 1;68(9):3286-94
 Abstract

Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
Cancer Cell. 2008 Jan;13(1):69-80
Abstract

Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov, Aiguo Li, Qin Su, Nicholas M. Donin, Sandra Pastorino, Benjamin W. Purow, Neil Christopher, Wei Zhang, John K. Park, and Howard A. Fine
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Cancer Cell, Vol 9, 391-403, May 2006
Abstract | Full Text |   Reprint | Supplemental Data | News

Li G, Chen Z, Hu YD, Wei H, Li D, Ji H, Wang DL
Autocrine factors sustain glioblastoma stem cell self-renewal
Oncol Rep. 2009 Feb;21(2):419-24
  Abstract

Daniel A. Lim, Soonmee Cha, Mary C. Mayo, Mei-Hsiu Chen, Evren Keles, Scott VandenBerg and Mitchel S. Berger
Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype
Neuro Oncol 2007 Oct 1. 9(4):424-429; DOI:10.1215/15228517-2007-023. First published on July 10, 2007
Abstract | Full Text | Reprint

Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng, Patrizia Tunici, Hiushan Ng, Iman R Abdulkadir, Lizhi Lu, Dwain Irvin, Keith L Black and John S Yu
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
Molecular Cancer 2006, 5:67. doi:10.1186/1476-4598-5-67. Published: 2 December 2006
Abstract | Full text | Reprint |Supplemental Data

Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng, Hiushan Ng, Patrizia Tunici, Dwain Irvin, Keith L. Black, and John S. Yu  
Chemoresistance of stem-like cells isolated from glioblastoma

AACR Meeting Abstracts, Apr 2006; 2006: 75
Abstract

Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, Junker M, Oefner PJ, Bogdahn U, Wischhusen J, Spang R, Storch A, Beier CP
Transcriptional Profiles of CD133+ and CD133- Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin
Cancer Res. 2010 Feb 9;. [Epub ahead of print]
  Abstract

Matos Rojas IA, Bertholdo D, Castillo M.
Stem cells: implications in the development of brain tumors.
Radiologia. 2011 Nov 23;. [Epub ahead of print]. Spanish
  Abstract |   Reprint |   Related articles

McCord AM, Jamal M, Shankavarum UT, Lang FF, Camphausen K, Tofilon PJ
Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
Mol Cancer Res. 2009 Apr;7(4):489-97
  Abstract

McLendon RE, Rich JN.
Glioblastoma Stem Cells: A Neuropathologist's View.
J Oncol. 2011;2011:397195.
Epub 2010 Nov 1.
  Abstract |   Reprint |   Related articles

Mercapide J, Rappa G, Anzanello F, King J, Fodstad O, Lorico A
Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma
Int J Cancer. 2010 Mar 1;126(5):1206-15. Epub 2009 Aug 3
  Abstract |   Full text |   Reprint

Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, de Tribolet N, Regli L, Wick W, Kouwenhoven MC, Hainfellner JA, Heppner FL, Dietrich PY, Zimmer Y, Cairncross JG, Janzer RC, Domany E, Delorenzi M, Stupp R, Hegi ME
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
J Clin Oncol. 2008 Jun 20;26(18):3015-24
 Abstract

Ichiro Nakano, Linda Liau, Jorge A. Lazareff, Paul Mischel, and Harley Kornblum
Neural stem cell genes and brain tumors: Identification of maternal embryonic leucine zipper kinase (MELK) as an important regulator of glioblastoma multiforme and medulloblastoma proliferation
AACR Meeting Abstracts, Apr 2006; 2006: 239
Abstract

Nishide K, Nakatani Y, Kiyonari H, Kondo T
Glioblastoma formation from cell population depleted of Prominin1-expressing cells
PLoS One. 2009 Aug 31;4(8):e6869°
  Abstract |   Full text |   Reprint

Oka N, Soeda A, Noda S, Iwama T.
Brain tumor stem cells from an adenoid glioblastoma multiforme
Neurol Med Chir (Tokyo). 2009 Apr;49(4):146-50; discussion 150-1
  Abstract |   Reprint

Pallini R, Ricci-Vitiani L, Banna GL, Signore M, Lombardi D, Todaro M, Stassi G, Martini M, Maira G, Larocca LM, De Maria R
Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
Clin Cancer Res. 2008 Dec 15;14(24):8205-12
  Abstract

Papagiannakopoulos T, Kosik KS
microRNAs: regulators of oncogenesis and stemness
BMC Med. 2008 Jun 24;6(1):15. [Epub ahead of print]
 Full text |  Reprint

Persano L, Rampazzo E, Della Puppa A, Pistollato F, Basso G.
The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications.
ScientificWorldJournal. 2011;11:1829-41. Epub 2011 Oct 23.
  Abstract |   Reprint |   Related articles

Piccirillo SG, Combi R, Cajola L, Patrizi A, Redaelli S, Bentivegna A, Baronchelli S, Maira G, Pollo B, Mangiola A, Dimeco F, Dalprà L, Vescovi AL.
Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
Oncogene. 2009 Mar 16. [Epub ahead of print]°
  Abstract

Sara GM Piccirillo, Angelo L Vescovi PhD
Brain tumour stem cells: possibilities of new therapeutic strategies
Expert Opinion on Biological Therapy, August 2007, Vol. 7, No. 8, Pages 1129-1135
Abstract

S. G. M. Piccirillo, B. A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco and A. L. Vescovi
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Nature 444, 761-765 (7 December 2006). doi:10.1038/nature05349
Abstract
Pistollato F, Abbadi S, Rampazzo E, Persano L, Puppa AD, Frasson C, Sarto E, Scienza R, D'Avella D, Basso G
Intratumoral Hypoxic Gradient Drives Stem Cells Distribution and MGMT Expression in Glioblastoma
Stem Cells. 2010 Mar 22. [Epub ahead of print]
  Abstract

Qiang L, Yang Y, Ma YJ, Chen FH, Zhang LB, Liu W, Qi Q, Lu N, Tao L, Wang XT, You QD, Guo QL
Isolation and characterization of cancer stem like cells in human glioblastoma cell lines
Cancer Lett. 2009 Feb 14; [Epub ahead of print]
  Abstract

Rafat N, Beck GC, Schulte J, Tuettenberg J, Vajkoczy P
Circulating endothelial progenitor cells in malignant gliomas
J Neurosurg. 2009 Jun 12. [Epub ahead of print]
  Abstract

Andrea Salmaggi, Amerigo Boiardi, Maurizio Gelati, Annamaria Russo, Chiara Calatozzolo, Emilio Ciusani, Francesca Luisa Sciacca, Arianna Ottolina, Eugenio Agostino Parati, Caterina La Porta, Giulio Alessandri, Carlo Marras, Danilo Croci, Marco De Rossi
Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
Glia. 2006 Dec;54(8):850-60. Epub 2006 Sep 15
Abstract

Sato A, Sakurada K, Kumabe T, Sasajima T, Beppu T, Asano K, Ohkuma H, Ogawa A, Mizoi K, Tominaga T, Kitanaka C, Kayama T
Association of stem cell marker CD133 expression with dissemination of glioblastomas
Neurosurg Rev. 2010 Apr;33(2):175-83; Epub 2010 Feb 5.
  Abstract

Schilling SH, Hjelmeland AB, Radiloff DR, Liu IM, Wakeman TP, Fielhauer JR, Foster EH, Lathia JD, Rich JN, Wang XF, Datto MB.
NDRG4 is required for cell cycle progression and survival in glioblastoma cells
J Biol Chem. 2009 Jul 10;. [Epub ahead of print]
  Abstract |   Reprint

Shen G, Shen F, Shi Z, Liu W, Hu W, Zheng X, Wen L, Yang X
Identification of cancer stem-like cells in the C6 glioma cell line and the limitation of current identification methods
In Vitro Cell Dev Biol Anim. 2008 Jul 2; [Epub ahead of print]
 Abstract

Sherry MM, Reeves A, Wu JK, Cochran BH.
STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
Stem Cells. 2009 Aug 5;. [Epub ahead of print]
  Abstract

Shervington A, Lu C
Expression of multidrug resistance genes in normal and cancer stem cells
Cancer Invest. 2008 Jun;26(5):535-42
 Abstract

  Anjali Shiras, Sivarajan Chettiar, Varsha Shepal, Ganeshkumar Rajendran, Rajendra Prasad, Padma Shastry
Spontaneous transformation of human adult non-tumorigenic stem cells to cancer stem cells is driven by Genomic Instability in a human model of Glioblastoma
Stem Cells. 2007 Mar 1; [Epub ahead of print]
Abstract

Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG
miR-124 and miR-137 inhibit proliferation of GBM cells and induce differentiation of brain tumor stem cells
BMC Med. 2008 Jun 24;6(1):14. [Epub ahead of print]
 Abstract |  Reprint

Suvà ML, Riggi N, Janiszewska M, Radovanovic I, Provero P, Stehle JC, Baumer K, Le Bitoux MA, Marino D, Cironi L, Marquez VE, Clément V, Stamenkovic I.
EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance
Cancer Res. 2009 Nov 24;. [Epub ahead of print]
  Abstract

Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R.
In vivo tracking of neural progenitor cell migration to glioblastomas
Hum Gene Ther. 2003 Sep 1;14(13):1247-54
Abstract

Tchoghandjian A, Baeza N, Colin C, Cayre M, Metellus P, Beclin C, Ouafik L, Figarella-Branger D.
A2B5 Cells from Human Glioblastoma have Cancer Stem Cell Properties
Brain Pathol. 2009 Feb 20;. [Epub ahead of print]
  Abstract |   Full text |   Reprint

Tomuleasa C, Soritau O, Rus-Ciuca D, Ioani H, Susman S, Petrescu M, Timis T, Cernea D, Kacso G, Irimie A, Florian IS.
Functional and molecular characterization of glioblastoma multiforme-derived cancer stem cells.
J BUON. 2010 Jul-Sep;15(3):583-91.
  Abstract |   Related articles

Tso CL, Shintaku P, Chen J, Liu Q, Liu J, Chen Z, Yoshimoto K, Mischel PS, Cloughesy TF, Liau LM, Nelson SF.
Primary glioblastomas express mesenchymal stem-like properties
Mol Cancer Res. 2006 Sep 1;4(9):607-19
 Abstract |  Full text |  Reprint

Cho-Lea Tso, Qinghai Liu, Kenneth Chung, Emil Vasquez, Carrie Ng, Angel Yu, Volkan Coskun, Stanley F. Nelson, Linda Liau, and Yi Sun
Mesenchymal properties in human glioblastoma stem cells
AACR Meeting Abstracts, Apr 2006; 2006: 241 - 242
Abstract

Patrizia Tunici, Lorena Bissola, Elena Lualdi, Bianca Pollo, Laura Cajola, Giovanni Broggi, Gabriella Sozzi and Gaetano Finocchiaro
Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
Molecular Cancer, 6 October 2004; 3:25
Abstract | Full text | Reprint

Varghese M, Olstorn H, Sandberg C, Vik-Mo EO, Noordhuis P, Nistér M, Berg-Johnsen J, Moe MC, Langmoen IA
A Comparison Between Stem Cells From The Adult Human Brain And From Brain Tumors
Neurosurgery. 2008 Dec;63(6):1022-1034
  Abstract

Wang J, Wang X, Jiang S, Lin P, Zhang J, Wu Y, Xiong Z, Ren JJ, Yang H.
Partial Biological Characterization of Cancer Stem-like Cell Line (WJ(2)) of Human Glioblastoma Multiforme
Cell Mol Neurobiol. 2008 Mar 19; [Epub ahead of print]
 Abstract

Wang J, Sakariassen PO, Tsinkalovsky O, Immervoll H, Boe SO, Svendsen A, Prestegarden L, Rosland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PO.
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells.
Int J Cancer. 2007 Oct 22; [Epub ahead of print]
Abstract

Christopher J. Wheeler, Asha Das, Gentao Liu, John S. Yu and Keith L. Black
Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy after Vaccination
Clinical Cancer Research Vol. 10, 5316-5326, August 15, 2004
Abstract | Full Text | Reprint

Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Sawaya R, Lang FF, Heimberger AB
Glioma-associated cancer-initiating cells induce immunosuppression
Clin Cancer Res. 2010 Jan 15;16(2):461-73. Epub 2010 Jan 12
  Abstract

Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Priebe W, Sawaya R, Lang FF, Heimberger AB.
Glioblastoma Cancer-Initiating Cells Inhibit T-Cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway
Mol Cancer Ther. 2010 Jan 6;. [Epub ahead of print]
  Abstract

Xu Q, Yuan X, Liu G, Black KL, Yu JS.
Hedgehog Signaling Regulates Brain Tumor Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas
Stem Cells. 2008 Sep 11; [Epub ahead of print]
  Abstract

Yu SC, Ping YF, Yi L, Zhou ZH, Chen JH, Yao XH, Gao L, Wang JM, Bian XW.
Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87
Cancer Lett. 2008 Mar 14; [Epub ahead of print]
  Abstract

Xiangpeng Yuan, James Curtin, Yizhi Xiong, Gentao Liu, Sebastian Waschsmann-Hogiu, Daniel L Farkas, Keith L Black and John S Yu
Isolation of cancer stem cells from adult glioblastoma multiforme
Oncogene. 2004 Dec 16;23(58):9392-400. Published online 22 November 2004
  Abstract |   Full Text |   Reprint

Kyuson Yun, Paula Knittle, Akio Mantani, Mark A. Israel
Id2 and Id4 expression and function in glioblastoma multiforme and neural stem cells
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.1065
 Abstract

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, Depinho RA
Pten and p53 Converge on c-Myc to Control Differentiation, Self-renewal, and Transformation of Normal and Neoplastic Stem Cells in Glioblastoma
Cold Spring Harb Symp Quant Biol. 2009 Jan 15;. [Epub ahead of print]
  Abstract

Gliomas


Bikeye SN, Colin C, Marie Y, Vampouille R, Ravassard P, Rousseau A, Boisselier B, Idbaih A, Calvo CF, Leuraud P, Lassalle M, El Hallani S, Delattre JY, Sanson M.
ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target
Cancer Cell Int. 2010 Jan 11;10:1
  Abstract |   Full text |   Reprint

Charles N, Ozawa T, Squatrito M, Bleau AM, Brennan CW, Hambardzumyan D, Holland EC
Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells
Cell Stem Cell. 2010 Feb 5;6(2):141-152
  Abstract

Das S, Srikanth M, Kessler JA
Cancer stem cells and glioma
Nat Clin Pract Neurol. 2008 Jul 15; [Epub ahead of print]
 Abstract

Hambardzumyan D, Squatrito M, Carbajal E, Holland EC
Glioma formation, cancer stem cells, and akt signaling
Stem Cell Rev. 2008 Sep;4(3):203-10
  Abstract

Huang Q, Zhang QB, Dong J, Wu YY, Shen YT, Zhao YD, Zhu YD, Diao Y, Wang AD, Lan Q
Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro
BMC Cancer. 2008 Oct 22;8(1):304. [Epub ahead of print]
  Abstract |   Reprint

Huang Q, Dong J, Zhu YD, Zhang QB, Ji XY, Wang AD, Lan Q
Isolation and culture of tumor stem cells from human brain glioma tissues
Zhonghua Zhong Liu Za Zhi. 2006 May;28(5):331-3
 Abstract

Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
Glia. 2002 Sep;39(3):193-206. Epub 2002 Jun 11

Abstract

Erica L. Jackson, Jose Manuel Garcia-Verdugo, Sara Gil-Perotin, Monica Roy, Alfredo Quinones-Hinojosa, Scott VandenBerg and Arturo Alvarez-Buylla
PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling 
Neuron, Volume 51, CNO 2, 20 July 2006, Pages 187-199; doi:10.1016/j.neuron.2006.06.012 ; Available online 19 July 2006
Abstract | Full Text | Reprint

Kang MK, Kang SK.
Tumorigenesis of Chemotherapeutic Drug-Resistant Cancer Stem-Like Cells in Brain Glioma.
Stem Cells Dev. 2007 Oct;16(5):837-848.
Abstract

Nakano I, Saigusa K, Kornblum HI
BMPing Off Glioma Stem Cells
Cancer Cell. 2008 Jan 8;13(1):3-4
Abstract

Ogden AT, Waziri AE, Lochhead RA, Fusco D, Lopez K, Ellis JA, Kang J, Assanah M, McKhann GM, Sisti MB, McCormick PC, Canoll P, Bruce JN
Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas
Neurosurgery. 2008 Feb;62(2):505-14
 Abstract

Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
Cancer Res. 2005 Jul 15;65(14):6207-19
 Abstract |  Full text |  Reprint

Soeda A, Park M, Lee D, Mintz A, Androutsellis-Theotokis A, McKay RD, Engh J, Iwama T, Kunisada T, Kassam AB, Pollack IF, Park DM
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
Oncogene. 2009 Aug 31. [Epub ahead of print]
  Abstract

Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura SI, Nakashima S, Kunisada T, Iwama T
Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
J Biol Chem. 2008 Feb 20; [Epub ahead of print]
 Abstract |  Reprint

Lixin Sun, Ai-Min Hui, Qin Su, Alexander Vortmeyer, Yuri Kotliarov, Sandra Pastorino, Antonino Passaniti, Jayant Menon, Jennifer Walling, Rolando Bailey, Marc Rosenblum, Tom Mikkelsen, and Howard A. Fine
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
Cancer Cell, Vol 9, 287-300, April 2006

Abstract Full Text | Reprint | News

Wang Y, Yang J, Zheng H, Tomasek GJ, Zhang P, McKeever PE, Lee EY, Zhu Y
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
Cancer Cell. 2009 Jun 2;15(6):514-26
  Abstract

Wu A, Oh S, Wiesner SM, Ericson K, Chen L, Hall WA, Champoux PE, Low WC, Ohlfest JR
Persistence of CD133(+) Cells in Human and Mouse Glioma Cell Lines: Detailed Characterization of GL261 Glioma Cells with Cancer Stem Cell-Like Properties
Stem Cells Dev. 2008 Feb 1;17(1):173-84
 Abstract

Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, Miraglia LJ, Rines DR, Skirboll SL, Schultz PG.
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation
Cell Stem Cell. 2010 Jan 8;6(1):37-47
  Abstract

Yawata T, Nakai E, Park KC, Chihara T, Kumazawa A, Toyonaga S, Masahira T, Nakabayashi H, Kaji T, Shimizu K
Enhanced expression of cancer testis antigen genes in glioma stem cells
Mol Carcinog. 2010 Jan 15;. [Epub ahead of print]
  Abstract

Zhang HR, Chen FL, Xu CP, Ping YF, Wang QL, Liang ZQ, Wang JM, Bian XW
Incorporation of endothelial progenitor cells into the neovasculature of malignant glioma xenograft
J Neurooncol. 2008 Dec 4. [Epub ahead of print]
  Abstract

Zhang XP, Zheng G, Zou L, Liu HL, Hou LH, Zhou P, Yin DD, Zheng QJ, Liang L, Zhang SZ, Feng L, Yao LB, Yang AG, Han H, Chen JY.
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
Mol Cell Biochem. 2008 Jan;307(1-2):101-8. Epub 2007 Sep 12
 Abstract

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, Depinho RA
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
Nature. 2008 Oct 23;455(7216):1129-33
  Abstract |  Full text |   Reprint

Xuesheng Zheng, Gang Shen, Xiaofeng Yang and Weiguo Liu
Most C6 Cells Are Cancer Stem Cells: Evidence from Clonal and Population Analyses
Cancer Research 67, 3691-3697, April 15, 2007. doi: 10.1158/0008-5472.CAN-06-3912
Abstract | Reprint


Gliomas (High-Grade)


Marcela Assanah, Richard Lochhead, Alfred Ogden, Jeffrey Bruce, James Goldman, and Peter Canoll
Glial Progenitors in Adult White Matter Are Driven to Form Malignant Gliomas by Platelet-Derived Growth Factor-Expressing Retroviruses
The Journal of Neuroscience, June 21, 2006, 26(25):6781-6790

Abstract | Full Text | Reprint

Bi CL, Fang JS, Chen FH, Wang YJ, Wu J
Chemoresistance of CD133(+) tumor stem cells from human brain glioma
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2007 Aug;32(4):568-73
 Abstract

Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A & Iavarone A
The transcriptional network for mesenchymal transformation of brain tumours
Nature advance online publication 23 December 2009
  Abstract |   News   News

Cho DY, Lin SZ, Yang WK, Hsu DM, Lin HL, Lee HC, Lee WY, Chiu SC.
The Role of Cancer Stem Cells (CD133+) in Malignant Gliomas.
Cell Transplant. 2010 Sep 30;. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Folkins C, Shaked Y, Man S, Tang T, Lee CR, Zhu Z, Hoffman RM, Kerbel RS
Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1
Cancer Res. 2009 Sep 15;69(18):7243-51. Epub 2009 Sep 8.
  Abstract

Toru Kondo, Takao Setoguchi, and Tetsuya Taga
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
PNAS | January 20, 2004 | vol. 101 | no. 3 | 781-786. Published online before print January 7, 2004
Abstract | Full Text | Reprint

Ping YF, Yao XH, Bian XW, Chen JH, Zhang R, Yi L, Zhou ZH
Activation of CXCR4 in human glioma stem cells promotes tumor angiogenesis
Zhonghua Bing Li Xue Za Zhi. 2007 Mar;36(3):179-83
 Abstract

Setoguchi T, Taga T, Kondo T
Cancer stem cells persist in many cancer cell lines
Cell Cycle. 2004 Apr;3(4):414-5. Epub 2004 Apr 1
 Abstract |  Reprint

Shih AH, Holland EC
Notch signaling enhances nestin expression in gliomas
Neoplasia. 2006 Dec;8(12):1072-82
  Abstract |   Full text |   Reprint

Taga T
Identification of cancer stem cells in the "side population"
Gan To Kagaku Ryoho. 2006 Mar;33(3):295-9
 Abstract

Zhao Y, Huang Q, Yang J, Lou M, Wang A, Dong J, Qin Z, Zhang T.
Autophagy impairment inhibits differentiation of glioma stem/progenitor cells
Brain Res. 2009 Dec 14;. [Epub ahead of print]
  Abstract


Gliomas (Low-rade)


Yigal Shoshan, Akiko Nishiyama, Ansi Chang, Sverre Mörk, Gene H. Barnett, John K. Cowell, Bruce D. Trapp, and Susan M. Staugaitis
Expression of oligodendrocyte progenitor cell antigens by gliomas: Implications for the histogenesis of brain tumors
PNAS, Vol. 96, CNO 18, 10361-10366, August 31, 1999
Abstract | Full text | Reprint


Gliomatosis Cerebri


Kong DS, Kim MH, Park WY, Suh YL, Lee JI, Park K, Kim JH, Nam DH
The progression of gliomas is associated with cancer stem cell phenotype
Oncol Rep. 2008 Mar;19(3):639-43
 Abstract


Gliosarcoma


Decarvalho AC, Nelson K, Lemke N, Lehman NL, Arbab AS, Kalkanis S, Mikkelsen T
Gliosarcoma Stem Cells Undergo Glial and Mesenchymal Differentiation In Vivo
Stem Cells. 2009 Nov 23;. [Epub ahead of print]
  Abstract


Medulloblastoma


Blazek ER, Foutch JL, Maki G
Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):1-5. Epub 2006 Nov 2
 Abstract

Christopher R. Calabrese, Helen Poppleton, Andrew Davidoff, and Richard J. Gilbertson
The cancer stem cell niche in medulloblastoma
AACR Meeting Abstracts, Apr 2006; 2006: 1325
Abstract

Li MC, Deng YW, Wu J, Chen FH, Liu JF, Fang JS
Isolation and characterization of brain tumor stem cells in human medulloblastoma
Ai Zheng. 2006 Feb;25(2):241-6
 Abstract

Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL.
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Cancer Cell. 2008 Aug 12;14(2):123-34
 Abstract

Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang JH, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN.
Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+ Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma
Stem Cells. 2008 Apr 10; [Epub ahead of print]
 Abstract

Sutter R, Shakhova O, Bhagat H, Behesti H, Sutter C, Penkar S, Santuccione A, Bernays R, Heppner FL, Schüller U, Grotzer M, Moch H, Schraml P, Marino S
Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas

Oncogene. 2010 Jan 11. [Epub ahead of print]
  Abstract

Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ.
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells
Cancer Cell. 2008 Aug 12;14(2):135-45
 Abstract


Meningioma


Hu D, Wang X, Mao Y, Zhou L.
Identification of CD105 (endoglin)-positive stem-like cells in rhabdoid meningioma.
J Neurooncol. 2011 Sep 6. [Epub ahead of print]
  Abstract |   Related articles


Metastasis


Alysha K. Croker and Alison L. Allan
Cancer Stem Cells: Implications for the progression and treatment of metastatic disease
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Dec-2007, doi: 10.1111/j.1582-4934.2007.00211.x
 Abstract |  Reprint

Feng Li, Benjamin Tiede, Joan Massagué, Yibin Kang
Beyond tumorigenesis: cancer stem cells in metastasis
Cell Research 17, 3 - 14 (01 Jan 2007). Published online 19 December 2006
 Abstract

Gao JX
Cancer stem cells: the lessons from precancerous stem cells
J Cell Mol Med. 2007 Dec 5; [Epub ahead of print]
 Abstract |  Reprint

R. R. Langley and I. J. Fidler
Tumor Cell-Organ Microenvironment Interactions in the Pathogenesis of Cancer Metastasis
Endocr. Rev., May 1, 2007; 28(3): 297 - 321
 Abstract


Oligoastrocytoma


Yi L, Zhou ZH, Ping YF, Chen JH, Yao XH, Feng H, Lu JY, Wang JM, Bian XW
Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma
Mod Pathol. 2007 Oct;20(10):1061-8. Epub 2007 Jul 27
 Abstract


Ologodendroglioma


Kyuson Yun and Mark A. Israel
Isolation of cancer stem cells from a mouse model of brain tumor
AACR Meeting Abstracts, Apr 2006; 2006: 642
Abstract

Pei Y, Wechsler-Reya RJ.
A Malignant Oligarchy: Progenitors Govern the Behavior of Oligodendrogliomas.
Cancer Cell. 2010 Dec 14;18(6):546-7.
  Abstract |   Reprint |   Related articles

Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, McKnight TR, Goldman SA, Weiss WA.
Non-Stem Cell Origin for Oligodendroglioma
Cancer Cell. 2010 Dec 14;18(6):669-82.
  Abstract |   Reprint | News |   Related articles


Osteosarcoma


Siclari VA, Qin L.
Targeting the osteosarcoma cancer stem cell.
Orthop Surg Res. 2010 Oct 27;5(1):78. [Epub ahead of print]
  Abstract |   Reprint |   Related articles


Pediatric Patients


Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, Kornblum HI
Cancerous stem cells can arise from pediatric brain tumors
PNAS, December 9, 2003, vol. 100 no. 25, 15178-15183
Abstract | Full text | Reprint


Komuro H, Saihara R, Shinya M, Takita J, Kaneko S, Kaneko M, Hayashi Y
Identification of side population cells (stem-like cell population) in pediatric solid tumor cell lines
J Pediatr Surg. 2007 Dec;42(12):2040-5
 Abstract


Side Population


Chua C, Zaiden N, Chong KH, See SJ, Wong MC, Ang BT, Tang C
Characterization of a side population of astrocytoma cells in response to temozolomide
J Neurosurg. 2008 Nov;109(5):856-66
  Abstract |   Reprint |   Related articles

Harris MA, Yang H, Low BE, Mukherje J, Guha A, Bronson RT, Shultz LD, Israel MA, Yun K
Cancer stem cells are enriched in the side population cells in a mouse model of glioma
Cancer Res. 2008 Dec 15;68(24):10051-9
  Abstract |   Reprint


Stem Cell Niche


Liu JM, Mao BY, Hong S, Liu YH, Wang XJ
The postoperative brain tumour stem cell (BTSC) niche and cancer recurrence
Adv Ther. 2008 May 7; [Epub ahead of print]
 Abstract

Jones DL, Wagers AJ
No place like home: anatomy and function of the stem cell niche
Nat Rev Mol Cell Biol. 2008 Jan;9(1):11-21
Abstract

Linheng Li and William B. Neaves
Normal Stem Cells and Cancer Stem Cells: The Niche Matters
Cancer Research 66, 4553-4557, May 1, 2006
 Abstract |  Full text |  Reprint

Sneddon JB, Werb Z
Location, location, location: the cancer stem cell niche
Cell Stem Cell. 2007 Dec 12;1(6):607-11
 Abstract

Wu YY, Huang Q, Dong J, Lan Q
Correlation of stem cell niche to genesis and development of tumor stem cells
Ai Zheng. 2008 Jan;27(1):109-12
Abstract


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