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Astrocytomas


Ma YH, Mentlein R, Knerlich F, Kruse ML, Mehdorn HM, Held-Feindt J.
Expression of stem cell markers in human astrocytomas of different WHO grades
J Neurooncol. 2007 Jul 5; [Epub ahead of print]
Abstract | Links

Nader Sanai, Anthony D. Tramontin, Alfredo Quiñones-Hinojosa, Nicholas M. Barbaro, Nalin Gupta, Sandeep Kunwar, Michael T. Lawton, Michael W. McDermott, Andrei T. Parsa, José Manuel-García Verdugo, Mitchel S. Berger, Arturo Alvarez-Buylla
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
Nature 427, 740 - 744 (19 February 2004); doi:10.1038/nature02301
Abstract | Links

Yang Y, Qiu Y, Ren W, Gong J, Chen F
An identification of stem cell-resembling gene expression profiles in high-grade astrocytomas
Mol Carcinog. 2008 Apr 7; [Epub ahead of print]
 Abstract |
Links | BL 7:8


Basic Science


Itzhak Avital, Andre L. Moreira, David S. Klimstra, Margaret Leversha, Esperanza B. Papadopoulos, Murray Brennan, Robert J. Downey
Donor-Derived Human Bone Marrow Cells Contribute to Solid Organ Cancers Developing After Bone Marrow Transplantation
Stem Cells Nov 2007; 25: 2903 - 2909 ; doi:10.1634/stemcells.2007-0409

Abstract | Links | BL 7:1

Blagosklonny MV.
Cancer stem cell and cancer stemloids: from biology to therapy
Cancer Biol Ther. 2007 Nov;6(11):1-7
 Abstract |
Links | BL 7:7

Kaisorn Chaichana, Grettel Zamora-Berridi, Joaquin Camara-Quintana, Alfredo Quiñones-Hinojosa
Neurosphere Assays: Growth Factors and Hormone Differences in Tumor and Nontumor Studies

Stem Cells Vol. 24 No. 12 December 2006, pp. 2851 -2857. First published online August 31, 2006
Abstract |
Full Text | Reprint | Links | BL 7:1

Michael F. Clarke, John E. Dick, Peter B. Dirks, Connie J. Eaves, Catriona H.M. Jamieson, D. Leanne Jones, Jane Visvader, Irving L. Weissman and Geoffrey M. Wahl
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
Cancer Res 2006;66:9339–44; October 1 2006, Volume 66, Issue 19
Abstract | Full Text | Reprint | Links

Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
Curr Biol. 2007 Jan 23;17(2):165-72. Epub 2006 Dec 28. Erratum in: Curr Biol. 2007 Jan 23;17(2):192
 Abstract |  Full Text |  Reprint |
Links | BL 7:5

Michael Dean
CANCER STEM CELLS: Redefining the Paradigm of Cancer Treatment Strategies
Mol. Interv., June 1, 2006; 6(3): 140 - 148
Abstract | Full Text | Reprint | Links

R. Ganguly and I. K. Puri
Mathematical model for the cancer stem cell hypothesis
Cell Proliferation, Volume 39, Issue 1, Page 3  - February 2006
Abstract | Full Text | Reprint | Links

Gennadi V. Glinsky, Olga Berezovska and Anna B. Glinskii
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
J. Clin. Invest. 115:1503-1521 (1 June 2005)

Abstract | Full Text | Reprint | Links

Wei Guo, Joseph L. Lasky, III and Hong Wu
Cancer Stem Cells
Pediatric Research 59:59R-64R (April 1, 2006)

Abstract | Full Text | Reprint | Links

Heffron CC, Gallagher MF, Guenther S, Sherlock J, Henfrey R, Martin C, Sheils O, O'Leary JJ.
Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model.
Anticancer Res. 2007 May-Jun;27(3A):1319-24.
Abstract | Links

Hellman S, Botnick L, Mauch P
Stem-Cell Biology and Cancer Therapy: The More Things Change...
J Clin Oncol. 2008 Feb 20;26(6):821-822
 Abstract |  Full Text |  Reprint |
Links | BL 7:5

S Hellman, U Reincke, L Botnick, and P Mauch
Functional organization of the hematopoietic stem cell compartment: implications for cancer and its therapy
JCO Apr 1 1983: 277-284
 Abstract |  Reprint |
Links | BL 7:5

Daniella Herszfeld, Ernst Wolvetang, Emma Langton-Bunker, Tung-Liang Chung, Adam A Filipczyk, Souheir Houssami, Pegah Jamshidi, Karen Koh, Andrew L Laslett, Anna Michalska, Linh Nguyen, Benjamin E Reubinoff, Irene Tellis, Jonathan M Auerbach, Carol J Ording, Leendert H J Looijenga & Martin F Pera
CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells
Nature Biotechnology, Advance online publication, Published online: 26 February 2006; DOI: doi:10.1038/nbt1197
Abstract | | Links

Hide T, Takezaki T, Nakamura H, Kuratsu J, Kondo T
Brain tumor stem cells as research and treatment targets
Brain Tumor Pathol. 2008 Nov ;25(2):67-72. Published online: 6 November 2008
  Abstract |
  Links |   Issue

Richard P. Hill, Roberto Perris
"Destemming" Cancer Stem Cells
JNCI 2007 99(19):1435-1440; doi:10.1093/jnci/djm136. Published online on September 25, 2007
 Abstract |
Links | BL 7:6

Kang MK, Her BI, Ko MH, Kim CH, Cha SH, Kang SK
Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma
BMC Neurosci. 2008 Jan 30;9(1):15
Abstract | Reprint |
Links | BL 7:4

Kondo T
Stem cell-like cancer cells in cancer cell lines
Cancer Biomark. 2007;3(4-5):245-50. Published Online: 28 September 2007
 Abstract |
Links | BL 7:5

Nathan D. Price, Greg Foltz, Anup Madan, Leroy Hood and Qiang Tian
Systems Biology and Cancer Stem Cells
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Nov-2007; doi: 10.1111/j.1582-4934.2007.00151.x
 Abstract |  Reprint |
Links | BL 7:6

Qu K, Ortoleva P
Understanding stem cell differentiation through self-organization theory
J Theor Biol. 2007 Oct 23;. [Epub ahead of print]
Abstract | Links | BL 7:1

Shipitsin M, Polyak K
The cancer stem cell hypothesis: in search of definitions, markers, and relevance
Lab Invest. 2008 Mar 31;. [Epub ahead of print]
 Abstract |
Links | BL 7:8

Soltysova A, Altanerova V, Altaner C
Cancer stem cells
Neoplasma. 2005;52(6):435-40
 Abstract |
  Links | BL 7:5

Matilde Todaro, Mileidys Perez Alea, Anna B. Di Stefano, Patrizia Cammareri, Louis Vermeulen, Flora Iovino, Claudio Tripodo, Antonio Russo, Gaspare Gulotta, Jan Paul Medema and Giorgio Stassi
Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4
Cell Stem Cell. 2007 Oct 10;1(4):389-402
 Abstract |
Links | BL 7:8

Timothy C. Wang
Bone Marrow-Derived Stem Cells: Implications for Cancer Prevention
AACR Meeting Abstracts, Nov 2006; 2006: PL03-02
Abstract | Links | BL 7:1

Wang Y, Armstrong SA
Cancer: inappropriate expression of stem cell programs?
Cell Stem Cell. 2008 Apr 9;2(4):297-9
 Abstract |
Links | BL 7:8

Max S. Wicha, Suling Liu and Gabriela Dontu
Cancer Stem Cells: An Old Idea—A Paradigm Shift
Cancer Research 66, 1883-1890, February 15, 2006

Abstract | Full Text | Reprint | Links


Brain Tumors


Ayuso-Sacido A, Graham C, Greenfield JP, Boockvar JA
The duality of epidermal growth factor receptor (EGFR) signaling and neural stem cell phenotype: cell enhancer or cell transformer?
Curr Stem Cell Res Ther. 2006 Sep;1(3):387-94
Abstract | Links | BL 7:3

Christopher Calabrese, Helen Poppleton, Mehmet Kocak, Twala L. Hogg, Christine Fuller, Blair Hamner, Eun Young Oh, M. Waleed Gaber, David Finklestein, Meredith Allen, Adrian Frank, Ildar T. Bayazitov, Stanislav S. Zakharenko, Amar Gajjar, Andrew Davidoff, and Richard J. Gilbertson
A Perivascular Niche for Brain Tumor Stem Cells
Cancer Cell. 2007 Jan;11(1):69-82
Abstract | Full Text | Reprint | Supplemental Data | Links

Caussinus E, Hirth F
Asymmetric stem cell division in development and cancer
Prog Mol Subcell Biol. 2007;45:205-25.
Abstract | Links

Clark PA, Treisman DM, Ebben J, Kuo JS.
Developmental signaling pathways in brain tumor-derived stem-like cells.
Dev Dyn. 2007 Nov 14;236(12):3297-3308 [Epub ahead of print]
Full Text | Reprint | Links

Deng YW, Fang JS, Li MC, Chen FH, Zhou XY, Wu J, Zhou RH, Fang F, Chen C, Lu M, Zeng FY
Correlation research between cancer stem cells and the pathological grades of neuroepithelial tumors
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Feb;31(1):45-51
 Abstract |
Links | BL 7:5

Anna Erlandsson, Karin Brännvall, Sigrun Gustafsdottir, Bengt Westermark and Karin Forsberg-Nilsson
Autocrine/Paracrine Platelet-Derived Growth Factor Regulates Proliferation of Neural Progenitor Cells
Cancer Research 66, 8042-8048, August 15, 2006
Abstract | Full Text | Reprint

Fang JS, Deng YW, Li MC, Chen FH, Wang YJ, Lu M, Fang F, Wu J, Yang ZY, Zhou XY, Wang F, Chen C
Isolation and identification of brain tumor stem cells from human brain neuroepithelial tumors
Zhonghua Yi Xue Za Zhi. 2007 Jan 30;87(5):298-303
 Abstract |
Links | BL 7:5

Fomchenko EI, Holland EC
Stem cells and brain cancer
Exp Cell Res. 2005 Jun 10;306(2):323-9. Epub 2005 Apr 14
 Abstract |
Links | BL 7:6

Galli R, Gritti A, Vescovi AL.
Adult Neural Stem Cells
Methods Mol Biol. 2008 Feb 5;438:67-84
 Abstract |
Links | BL 7:7

Jandial R, U H, Levy ML, Snyder EY.
Brain tumor stem cells and the tumor microenvironmen
Neurosurg Focus. 2008 Mar;24(3-4):E27
  Abstract |   Full Text |   Reprint |
Links | BL 7:7

Harley Kornblum, Houman Hemmati, Ichiro Nakano, Michael Masterman-Smith, Marianne Bronner-Fraser, Jorge Lazareff, Stan Nelson, Linda Liau, Paul Mischel, Daniel H. Geschwind
Neural stem cells, brain tumors, and brain tumor stem cells
AACR 96th Annual Meeting, April 16-20, 2005, Anaheim/Orange County, CA
Proc Amer Assoc Cancer Res 2005;46:[SY23]

Abstract | Links

Ichiro Nakano and Harley I. Kornblum
Brain Tumor Stem Cells
Pediatric Research 59:54R-58R (April 1, 2006)

Abstract | Full Text | Reprint | Links

Nicolis SK
Cancer stem cells and "stemness" genes in neuro-oncology
Neurobiol Dis. 2007 Feb;25(2):217-29. Epub 2006 Dec 1
 Abstract |
Links | BL 7:6

Ji XY, Huang Q, Dong J, Zhu YD, Wang AD, Lan Q
Characteristics of morphology, differentiation related marker, and proliferation dynamics of differentiated brain tumor stem cells in vitro
Zhonghua Yi Xue Za Zhi. 2006 Jun 20;86(23):1604-9
 Abstract |
Links | BL 7:5

Oliver TG, Wechsler-Reya RJ
Getting at the root and stem of brain tumors
Neuron. 2004 Jun 23;42(6):885-8
Abstract | Full Text | Reprint | Links

Francesca Pentimalli
Cancer Stem Cells: BMPs on the Brain
Nature Reviews Cancer 7, 4 (January 2007) | doi:10.1038/nrc2065
 Full Text |  Reprint |
Links | BL 7:10

Cosima V. Pfenninger, Teona Roschupkina, Falk Hertwig, Denise Kottwitz, Elisabet Englund, Johan Bengzon, Sten Eirik Jacobsen, and Ulrike A. Nuber
CD133 Is Not Present on Neurogenic Astrocytes in the Adult Subventricular Zone, but on Embryonic Neural Stem Cells, Ependymal Cells, and Glioblastoma Cells
Cancer Research 67, 5727-5736, June 15, 2007. doi: 10.1158/0008-5472.CAN-07-0183
Abstract | Full Text | Reprint | Links | BL 7:2

Rich JN, Eyler CE
Cancer Stem Cells in Brain Tumor Biology
Cold Spring Harb Symp Quant Biol. 2009 Mar 27; [Epub ahead of print]
  Abstract |   Links |   Issue

Rubio D, Garcia S, Paz MF, De la Cueva T, Lopez-Fernandez LA, Lloyd AC, Garcia-Castro J, Bernad A  
Molecular Characterization of Spontaneous Mesenchymal Stem Cell Transformation
PLoS ONE. 2008; 3(1): e1398. Published online 2008 January 2. doi: 10.1371/journal.pone.0001398
Abstract | Full Text |
Reprint | Links | BL 7:2

Sanai N, Berger MS.
Biology of brain tumor stem cells
Neurosurg Focus. 2008 Mar;24(3-4):E26
 Abstract |  Full Text |  Reprint |
Links | BL 7:7

Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke, Jeremy A. Squire, Jane Bayani, Takuichiro Hide, R. Mark Henkelman, Michael D. Cusimano & Peter B. Dirks
Identification of human brain tumour initiating cells
Nature 432, 396 - 401 (18 November 2004)
Abstract | Reprint | Links

Singh SK, Clarke ID, Hide T, Dirks PB
Cancer stem cells in nervous system tumors
Oncogene. 2004 Sep 20;23(43):7267-73
  Abstract |   Full Text |   Reprint |   Links |   Issue

Sheila K. Singh, Ian D. Clarke, Mizuhiko Terasaki, Victoria E. Bonn, Cynthia Hawkins, Jeremy Squire and Peter B. Dirks
Identification of a Cancer Stem Cell in Human Brain Tumors
Cancer Research 63, 5821-5828, September 15, 2003
Abstract | Full Text | Reprint | Links

Veeravagu A, Bababeygy SR, Kalani MS, Hou L, Tse V
The Cancer Stem Cell-Vascular Niche Complex in Brain Tumor Formation
Stem Cells Dev. 2008 Apr 22;. [Epub ahead of print]
 Abstract |
Links | BL 7:9

Angelo L. Vescovi, Rossella Galli and Brent A. Reynolds
Brain tumour stem cells
Nature Reviews Cancer 6, 425-436 (June 2006)
Abstract |   Full Text |   Reprint | Links

Darius Widera, Aljoscha Kaus, Christian Kaltschmidt and Barbara Kaltschmidt
Neural stem cells, inflammation and NF-κB: basic principle of maintenance and repair or origin of brain tumours?
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Dec-2007, doi: 10.1111/j.1582-4934.2007.00208.x
 Abstract |  Reprint |
Links | BL 7:5

Xie Z, Chin LS.
Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells
Neurosurg Focus. 2008 Mar;24(3-4):E25
 Abstract |  Full Text |  Reprint |
Links | BL 7:7

Yao Y, Tang X, Li S, Mao Y, Zhou L
Brain tumor stem cells: view from cell proliferation
Surg Neurol. 2009 Mar;71(3):274-9
  Abstract |   Links |   Issue

Yao Y, Tao R, Wang X, Wang Y, Mao Y, Zhou L
B7-H1 is correlated with the malignancy grade of gliomas but it is not the privilege of tumor stem-like cells
Neuro Oncol. 2009 Mar 5;. [Epub ahead of print]
  Abstract |   Links |   Issue

Zhang QB, Ji XY, Huang Q, Dong J, Zhu YD, Lan Q
Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells
Cell Res. 2006 Dec;16(12):909-15
 Abstract |  Full Text |  Reprint |
Links | BL 7:5


CSC hypothesis: Evaluation


Richard P. Hill
Identifying Cancer Stem Cells in Solid Tumors: Case Not Proven
Cancer Research 66, 1891-1896, February 15, 2006

Abstract | Full Text | Reprint | Links

Jin F, Zhao L, Zhao HY, Guo SG, Feng J, Jiang XB, Zhang SL, Wei YJ, Fu R, Zhao JS
Paradoxical expression of anti-apoptotic and MRP genes on cancer stem-like cell isolated from TJ905 glioblastoma multiforme cell line
Cancer Invest. 2008 May;26(4):338-43
 Abstract |
Links | BL 7:10

Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A. 
Tumor growth need not be driven by rare cancer stem cells.
Science. 2007 Jul 20;317(5836):337.
Abstract | Full Text | Reprint | Links

Yoo MH, Hatfield DL.
The Cancer Stem Cell Theory: Is It Correct?
Mol Cells. 2008 Aug 14;26(5). [Epub ahead of print]
 Abstract |  Reprint |
Links |  BL 7:17


Ependymoma


Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ
Radial glia cells are candidate stem cells of ependymoma
Cancer Cell. 2005 Oct;8(4):323-35. Erratum in: Cancer Cell. 2006 Jan;9(1):70
 Abstract |  Full Text |  Reprint |
Links | BL 7:15


Glioblastoma


Altaner C
Glioblastoma and stem cells
Neoplasma. 2008;55(5):369-74
 Abstract |
Links | BL 7:15

Annabi B, Laflamme C, Sina A, Lachambre MP, Béliveau R.
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells
J Neuroinflammation. 2009 Mar 9;6:8
  Abstract |   Full Text |   Reprint |   Links |   Issue

Balenci L, Clarke ID, Dirks PB, Assard N, Ducray F, Jouvet A, Belin MF, Honnorat J, Baudier J.
IQGAP1 Protein Specifies Amplifying Cancer Cells in Glioblastoma Multiforme.
Cancer Res. 2006 Sep 15;66(18):9074-82.
Abstract | Full Text | Reprint | Links

G. L. Banna, R. Pallini, L. Ricci-Vitiani, M. Signore, D. Lombardi, M. Martini, G. Maira, D. Giuffrida, L. M. Larocca, and R. De Maria
High prognostic potential of glioblastoma stem cell analysis
ASCO Meeting Abstracts, Jun 2007; 25: 10580
Abstract | Links | BL 7:2

Shideng Bao, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hjelmeland, Mark W. Dewhirst, Darell D. Bigner and Jeremy N. Rich
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Nature advance online publication 18 October 2006
Abstract | Links

Shideng Bao, Qiulian Wu, Sith Sathornsumetee, Yueling Hao, Zhizhong Li, Anita B. Hjelmeland, Qing Shi, Roger E. McLendon, Darell D. Bigner and Jeremy N. Rich
Stem Cell–like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor
Cancer Research 66, 7843-7848, August 15, 2006
Abstract | Full Text | Reprint | Links

Dagmar Beier, Peter Hau, Martin Proescholdt, Annette Lohmeier, Jörg Wischhusen, Peter J. Oefner, Ludwig Aigner, Alexander Brawanski, Ulrich Bogdahn, and Christoph P. Beier
CD133+ and CD133 Glioblastoma-Derived Cancer Stem Cells Show Differential Growth Characteristics and Molecular Profiles
Cancer Research 67, 4010-4015, May 1, 2007. doi: 10.1158/0008-5472.CAN-06-4180
Abstract | Reprint | Links | BL 7:2

Xiu-wu Bian, Xiao-hong Yao, Yi-fang Ping, Jian-hong Chen, and Ji Ming Wang
Glioblastoma stem cells produce angiogenic factors through activation of chemokine receptor CXCR4
FASEB J. 2007 Mar; 21:lb314
Abstract | Links | BL 7:2

Ali Jourabchi Ghods, Dwain Irvin, Gentao Liu, Xiangpeng Yuan, Iman R. Abdulkadir, Patrizia Tunici, Bindu Konda, Sebastian Wachsmann-Hogiu, Keith L. Black, John S. Yu
Spheres Isolated from 9L Gliosarcoma Rat Cell Line Possess Chemoresistant and Aggressive Cancer Stem-Like Cells
Stem Cells Jul 2007; 25: 1645 - 1653 ; doi:10.1634/stemcells.2006-0624
Abstract | Links | BL 7:1

Godlewski J, Newton HB, Chiocca EA, Lawler SE.
MicroRNAs and glioblastoma; the stem cell connection
Cell Death Differ. 2009 Jun 12;. [Epub ahead of print]
  Abstract |   Links |   Issue

Huttner HB, Janich P, Köhrmann M, Jászai J, Siebzehnrubl F, Blümcke I, Suttorp M, Gahr M, Kuhnt D, Nimsky C, Krex D, Schackert G, Löwenbrück K, Reichmann H, Jüttler E, Hacke W, Schellinger PD, Schwab S, Wilsch-Bräuninger M, Marzesco AM, Corbeil D
The Stem Cell Marker Prominin-1/CD133 On Membrane Particles In Human Cerebrospinal Fluid Offers Novel Approaches For Studying CNS Disease
Stem Cells. 2007 Dec 20; [Epub ahead of print]
Abstract | Links | BL 7:1

Rossella Galli, Elena Binda, Ugo Orfanelli, Barbara Cipelletti, Angela Gritti, Simona De Vitis, Roberta Fiocco, Chiara Foroni, Francesco Dimeco and Angelo Vescovi
Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma
Cancer Research 64, 7011-7021, October 1, 2004
Abstract | Full Text | Reprint | Links

Christine Glanz, Johan Rebetz, Ylva Stewénius, David Gisselsson, Anna Darabi, Elisabet Englund, Leif G. Salford, Bengt Widegren, Xiaolong Fan
Genetic identification of glioblastoma maintaining cells in a xenograft model
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.2045

Abstract | Links

Caroline Gregorian, Matthias Groszer, Qing Yue, Xin Liu, Hong Wu
The Role of PTEN Tumor Suppressor in Brain Growth and Tumor Development
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.2075
Abstract | Links

Günther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K.
Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
Oncogene. 2007 Nov 26; [Epub ahead of print]
Abstract | Links

Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
Nat Genet. 2000 May;25(1):55-7

Abstract | Full Text | Reprint | Links

Jin F, Li HS, Zhao L, Wei YJ, Zhang H, Guo YJ, Pang R, Jiang XB, Zhao HY.
Expression of anti-apoptotic and multi-drug resistance-associated protein genes in cancer stem cell isolated from TJ905 glioblastoma multiforme cell line
Zhonghua Yi Xue Za Zhi. 2008 Aug 26;88(33):2312-6
  Abstract |   Links |   Issue

Kang MK, Her BI, Ko MH, Kim CH, Cha SH, Kang SK
Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma
BMC Neurosci. 2008 Jan 30;9(1):15
Abstract | Reprint |
Links | BL 7:4

Kroonen J, Nguyen-Khac MT, Deprez M, Rogister B, Robe P.
Glioblastoma, an example of translational research?
Rev Med Liege. 2008 May-Jun;63(5-6):251-6
 Abstract |
Links | BL 7:16

Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF
Pten haploinsufficiency accelerates formation of high-grade astrocytomas
Cancer Res. 2008 May 1;68(9):3286-94
 Abstract |
Links | BL 7:10

Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
Cancer Cell. 2008 Jan;13(1):69-80
Abstract | Links | BL 7:2

Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov, Aiguo Li, Qin Su, Nicholas M. Donin, Sandra Pastorino, Benjamin W. Purow, Neil Christopher, Wei Zhang, John K. Park, and Howard A. Fine
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Cancer Cell, Vol 9, 391-403, May 2006
Abstract | Full Text |   Reprint | Supplemental Data | News | Links

Li G, Chen Z, Hu YD, Wei H, Li D, Ji H, Wang DL
Autocrine factors sustain glioblastoma stem cell self-renewal
Oncol Rep. 2009 Feb;21(2):419-24
  Abstract |   Links |   Issue

Daniel A. Lim, Soonmee Cha, Mary C. Mayo, Mei-Hsiu Chen, Evren Keles, Scott VandenBerg and Mitchel S. Berger
Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype
Neuro Oncol 2007 Oct 1. 9(4):424-429; DOI:10.1215/15228517-2007-023. First published on July 10, 2007

Abstract | Full Text | Reprint | Links | BL 7:2

Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng, Patrizia Tunici, Hiushan Ng, Iman R Abdulkadir, Lizhi Lu, Dwain Irvin, Keith L Black and John S Yu
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
Molecular Cancer 2006, 5:67. doi:10.1186/1476-4598-5-67. Published: 2 December 2006
Abstract | Full Text | Reprint |Supplemental Data | Links

Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng, Hiushan Ng, Patrizia Tunici, Dwain Irvin, Keith L. Black, and John S. Yu  
Chemoresistance of stem-like cells isolated from glioblastoma

AACR Meeting Abstracts, Apr 2006; 2006: 75
Abstract | Links | BL 7:1

McCord AM, Jamal M, Shankavarum UT, Lang FF, Camphausen K, Tofilon PJ
Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
Mol Cancer Res. 2009 Apr;7(4):489-97
  Abstract |   Links |   Issue

Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, de Tribolet N, Regli L, Wick W, Kouwenhoven MC, Hainfellner JA, Heppner FL, Dietrich PY, Zimmer Y, Cairncross JG, Janzer RC, Domany E, Delorenzi M, Stupp R, Hegi ME
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
J Clin Oncol. 2008 Jun 20;26(18):3015-24
 Abstract | Links | BL 7:13

Ichiro Nakano, Linda Liau, Jorge A. Lazareff, Paul Mischel, and Harley Kornblum
Neural stem cell genes and brain tumors: Identification of maternal embryonic leucine zipper kinase (MELK) as an important regulator of glioblastoma multiforme and medulloblastoma proliferation
AACR Meeting Abstracts, Apr 2006; 2006: 239
Abstract | Links | BL 7:2

Oka N, Soeda A, Noda S, Iwama T.
Brain tumor stem cells from an adenoid glioblastoma multiforme
Neurol Med Chir (Tokyo). 2009 Apr;49(4):146-50; discussion 150-1
  Abstract |   Reprint |   Links |   Issue

Pallini R, Ricci-Vitiani L, Banna GL, Signore M, Lombardi D, Todaro M, Stassi G, Martini M, Maira G, Larocca LM, De Maria R
Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
Clin Cancer Res. 2008 Dec 15;14(24):8205-12
  Abstract |   Links |   Issue

Papagiannakopoulos T, Kosik KS
microRNAs: regulators of oncogenesis and stemness
BMC Med. 2008 Jun 24;6(1):15. [Epub ahead of print]
 Full Text |  Reprint | Links | BL 7:13

Piccirillo SG, Combi R, Cajola L, Patrizi A, Redaelli S, Bentivegna A, Baronchelli S, Maira G, Pollo B, Mangiola A, Dimeco F, Dalprà L, Vescovi AL.
Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
Oncogene. 2009 Mar 16. [Epub ahead of print]°
  Abstract |   Links |   Issue

Sara GM Piccirillo, Angelo L Vescovi PhD
Brain tumour stem cells: possibilities of new therapeutic strategies
Expert Opinion on Biological Therapy, August 2007, Vol. 7, No. 8, Pages 1129-1135
Abstract | Links

S. G. M. Piccirillo, B. A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco and A. L. Vescovi
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Nature 444, 761-765 (7 December 2006). doi:10.1038/nature05349
Abstract | Links

Qiang L, Yang Y, Ma YJ, Chen FH, Zhang LB, Liu W, Qi Q, Lu N, Tao L, Wang XT, You QD, Guo QL
Isolation and characterization of cancer stem like cells in human glioblastoma cell lines
Cancer Lett. 2009 Feb 14; [Epub ahead of print]
  Abstract |   Links |   Issue

Andrea Salmaggi, Amerigo Boiardi, Maurizio Gelati, Annamaria Russo, Chiara Calatozzolo, Emilio Ciusani, Francesca Luisa Sciacca, Arianna Ottolina, Eugenio Agostino Parati, Caterina La Porta, Giulio Alessandri, Carlo Marras, Danilo Croci, Marco De Rossi
Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
Glia. 2006 Dec;54(8):850-60. Epub 2006 Sep 15
Abstract | Links

Shen G, Shen F, Shi Z, Liu W, Hu W, Zheng X, Wen L, Yang X
Identification of cancer stem-like cells in the C6 glioma cell line and the limitation of current identification methods
In Vitro Cell Dev Biol Anim. 2008 Jul 2; [Epub ahead of print]
 Abstract |
Links | BL 7:14

Shervington A, Lu C
Expression of multidrug resistance genes in normal and cancer stem cells
Cancer Invest. 2008 Jun;26(5):535-42
 Abstract | Links | BL 7:13

  Anjali Shiras, Sivarajan Chettiar, Varsha Shepal, Ganeshkumar Rajendran, Rajendra Prasad, Padma Shastry
Spontaneous transformation of human adult non-tumorigenic stem cells to cancer stem cells is driven by Genomic Instability in a human model of Glioblastoma
Stem Cells. 2007 Mar 1; [Epub ahead of print]
Abstract | Links

Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG
miR-124 and miR-137 inhibit proliferation of GBM cells and induce differentiation of brain tumor stem cells
BMC Med. 2008 Jun 24;6(1):14. [Epub ahead of print]
 Abstract |  Reprint | Links | BL 7:13

Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R.
In vivo tracking of neural progenitor cell migration to glioblastomas
Hum Gene Ther. 2003 Sep 1;14(13):1247-54
Abstract
| Links

Tchoghandjian A, Baeza N, Colin C, Cayre M, Metellus P, Beclin C, Ouafik L, Figarella-Branger D.
A2B5 Cells from Human Glioblastoma have Cancer Stem Cell Properties
Brain Pathol. 2009 Feb 20;. [Epub ahead of print]
  Abstract |   Full Text |   Reprint |   Links |   Issue

Tso CL, Shintaku P, Chen J, Liu Q, Liu J, Chen Z, Yoshimoto K, Mischel PS, Cloughesy TF, Liau LM, Nelson SF.
Primary glioblastomas express mesenchymal stem-like properties
Mol Cancer Res. 2006 Sep 1;4(9):607-19
 Abstract |  Full Text |  Reprint |
Links | BL 7:16

Cho-Lea Tso, Qinghai Liu, Kenneth Chung, Emil Vasquez, Carrie Ng, Angel Yu, Volkan Coskun, Stanley F. Nelson, Linda Liau, and Yi Sun
Mesenchymal properties in human glioblastoma stem cells
AACR Meeting Abstracts, Apr 2006; 2006: 241 - 242
Abstract | Links | BL 7:2

Patrizia Tunici, Lorena Bissola, Elena Lualdi, Bianca Pollo, Laura Cajola, Giovanni Broggi, Gabriella Sozzi and Gaetano Finocchiaro
Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
Molecular Cancer, 6 October 2004; 3:25
Abstract | Full Text |
Reprint | Links

Varghese M, Olstorn H, Sandberg C, Vik-Mo EO, Noordhuis P, Nistér M, Berg-Johnsen J, Moe MC, Langmoen IA
A Comparison Between Stem Cells From The Adult Human Brain And From Brain Tumors
Neurosurgery. 2008 Dec;63(6):1022-1034
  Abstract |   Links |   Issue

Wang J, Wang X, Jiang S, Lin P, Zhang J, Wu Y, Xiong Z, Ren JJ, Yang H.
Partial Biological Characterization of Cancer Stem-like Cell Line (WJ(2)) of Human Glioblastoma Multiforme
Cell Mol Neurobiol. 2008 Mar 19; [Epub ahead of print]
 Abstract |
Links | BL 7:7

Wang J, Sakariassen PO, Tsinkalovsky O, Immervoll H, Boe SO, Svendsen A, Prestegarden L, Rosland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PO.
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells.
Int J Cancer. 2007 Oct 22; [Epub ahead of print]
Abstract | Links

Christopher J. Wheeler, Asha Das, Gentao Liu, John S. Yu and Keith L. Black
Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy after Vaccination
Clinical Cancer Research Vol. 10, 5316-5326, August 15, 2004
Abstract | Full Text | Reprint | Links

Xu Q, Yuan X, Liu G, Black KL, Yu JS.
Hedgehog Signaling Regulates Brain Tumor Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas
Stem Cells. 2008 Sep 11; [Epub ahead of print]
  Abstract |
Links |   BL 7:19

Yu SC, Ping YF, Yi L, Zhou ZH, Chen JH, Yao XH, Gao L, Wang JM, Bian XW.
Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87
Cancer Lett. 2008 Mar 14; [Epub ahead of print]
  Abstract |
Links | BL 7:7

Xiangpeng Yuan, James Curtin, Yizhi Xiong, Gentao Liu, Sebastian Waschsmann-Hogiu, Daniel L Farkas, Keith L Black and John S Yu
Isolation of cancer stem cells from adult glioblastoma multiforme
Oncogene advance online publication 22 November 2004
Abstract | Links

Kyuson Yun, Paula Knittle, Akio Mantani, Mark A. Israel
Id2 and Id4 expression and function in glioblastoma multiforme and neural stem cells
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.1065
 Abstract
| Links

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, Depinho RA
Pten and p53 Converge on c-Myc to Control Differentiation, Self-renewal, and Transformation of Normal and Neoplastic Stem Cells in Glioblastoma
Cold Spring Harb Symp Quant Biol. 2009 Jan 15;. [Epub ahead of print]
  Abstract |   Links |   Issue


Gliomas


Das S, Srikanth M, Kessler JA
Cancer stem cells and glioma
Nat Clin Pract Neurol. 2008 Jul 15; [Epub ahead of print]
 Abstract |
Links | BL 7:15

Hambardzumyan D, Squatrito M, Carbajal E, Holland EC
Glioma formation, cancer stem cells, and akt signaling
Stem Cell Rev. 2008 Sep;4(3):203-10
  Abstract |   Links |   Issue

Huang Q, Zhang QB, Dong J, Wu YY, Shen YT, Zhao YD, Zhu YD, Diao Y, Wang AD, Lan Q
Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro
BMC Cancer. 2008 Oct 22;8(1):304. [Epub ahead of print]
  Abstract |   Reprint |
  Links |   Issue

Huang Q, Dong J, Zhu YD, Zhang QB, Ji XY, Wang AD, Lan Q
Isolation and culture of tumor stem cells from human brain glioma tissues
Zhonghua Zhong Liu Za Zhi. 2006 May;28(5):331-3
 Abstract |
Links | BL 7:5

Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
Glia. 2002 Sep;39(3):193-206. Epub 2002 Jun 11

Abstract
| Links

Erica L. Jackson, Jose Manuel Garcia-Verdugo, Sara Gil-Perotin, Monica Roy, Alfredo Quinones-Hinojosa, Scott VandenBerg and Arturo Alvarez-Buylla
PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling 
Neuron, Volume 51, Issue 2, 20 July 2006, Pages 187-199; doi:10.1016/j.neuron.2006.06.012 ; Available online 19 July 2006
Abstract | Full Text | Reprint | Links

Kang MK, Kang SK.
Tumorigenesis of Chemotherapeutic Drug-Resistant Cancer Stem-Like Cells in Brain Glioma.
Stem Cells Dev. 2007 Oct;16(5):837-848.
Abstract | Links

Nakano I, Saigusa K, Kornblum HI
BMPing Off Glioma Stem Cells
Cancer Cell. 2008 Jan 8;13(1):3-4
Abstract | Links | BL 7:2

Ogden AT, Waziri AE, Lochhead RA, Fusco D, Lopez K, Ellis JA, Kang J, Assanah M, McKhann GM, Sisti MB, McCormick PC, Canoll P, Bruce JN
Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas
Neurosurgery. 2008 Feb;62(2):505-14
 Abstract |
Links | BL 7:8

Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
Cancer Res. 2005 Jul 15;65(14):6207-19
 Abstract |  Full Text |  Reprint |
Links | BL 7:5

Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura SI, Nakashima S, Kunisada T, Iwama T
Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
J Biol Chem. 2008 Feb 20; [Epub ahead of print]
 Abstract |  Reprint |
Links | BL 7:5

Lixin Sun, Ai-Min Hui, Qin Su, Alexander Vortmeyer, Yuri Kotliarov, Sandra Pastorino, Antonino Passaniti, Jayant Menon, Jennifer Walling, Rolando Bailey, Marc Rosenblum, Tom Mikkelsen, and Howard A. Fine
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
Cancer Cell, Vol 9, 287-300, April 2006

Abstract Full Text | Reprint | News
| Links

Wu A, Oh S, Wiesner SM, Ericson K, Chen L, Hall WA, Champoux PE, Low WC, Ohlfest JR
Persistence of CD133(+) Cells in Human and Mouse Glioma Cell Lines: Detailed Characterization of GL261 Glioma Cells with Cancer Stem Cell-Like Properties
Stem Cells Dev. 2008 Feb 1;17(1):173-84
 Abstract | Links | BL 7:5

Zhang HR, Chen FL, Xu CP, Ping YF, Wang QL, Liang ZQ, Wang JM, Bian XW
Incorporation of endothelial progenitor cells into the neovasculature of malignant glioma xenograft
J Neurooncol. 2008 Dec 4. [Epub ahead of print]
  Abstract |   Links |   Issue

Zhang XP, Zheng G, Zou L, Liu HL, Hou LH, Zhou P, Yin DD, Zheng QJ, Liang L, Zhang SZ, Feng L, Yao LB, Yang AG, Han H, Chen JY.
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
Mol Cell Biochem. 2008 Jan;307(1-2):101-8. Epub 2007 Sep 12
 Abstract |
Links | BL 7:5

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, Depinho RA
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
Nature. 2008 Oct 23;455(7216):1129-33
  Abstract |  Full Text |   Reprint |
Links |   Issue

Xuesheng Zheng, Gang Shen, Xiaofeng Yang and Weiguo Liu
Most C6 Cells Are Cancer Stem Cells: Evidence from Clonal and Population Analyses
Cancer Research 67, 3691-3697, April 15, 2007. doi: 10.1158/0008-5472.CAN-06-3912
Abstract | Reprint | Links | BL 7:5

Wang Y, Yang J, Zheng H, Tomasek GJ, Zhang P, McKeever PE, Lee EY, Zhu Y
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
Cancer Cell. 2009 Jun 2;15(6):514-26
  Abstract |   Links |   Issue


Gliomas (High-Grade)


Marcela Assanah, Richard Lochhead, Alfred Ogden, Jeffrey Bruce, James Goldman, and Peter Canoll
Glial Progenitors in Adult White Matter Are Driven to Form Malignant Gliomas by Platelet-Derived Growth Factor-Expressing Retroviruses
The Journal of Neuroscience, June 21, 2006, 26(25):6781-6790

Abstract | Full Text | Reprint
| Links

Bi CL, Fang JS, Chen FH, Wang YJ, Wu J
Chemoresistance of CD133(+) tumor stem cells from human brain glioma
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2007 Aug;32(4):568-73
 
Abstract | Links | BL 7:5

Toru Kondo, Takao Setoguchi, and Tetsuya Taga
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
PNAS | January 20, 2004 | vol. 101 | no. 3 | 781-786. Published online before print January 7, 2004
Abstract | Full Text | Reprint | Links

Ping YF, Yao XH, Bian XW, Chen JH, Zhang R, Yi L, Zhou ZH
Activation of CXCR4 in human glioma stem cells promotes tumor angiogenesis
Zhonghua Bing Li Xue Za Zhi. 2007 Mar;36(3):179-83
 Abstract |
Links | BL 7:5

Setoguchi T, Taga T, Kondo T
Cancer stem cells persist in many cancer cell lines
Cell Cycle. 2004 Apr;3(4):414-5. Epub 2004 Apr 1
 Abstract |  Reprint |
  Links | BL 7:5

Taga T
Identification of cancer stem cells in the "side population"
Gan To Kagaku Ryoho. 2006 Mar;33(3):295-9
 Abstract |
 Links | BL 7:5


Gliomas (Low Grade)


Yigal Shoshan, Akiko Nishiyama, Ansi Chang, Sverre Mörk, Gene H. Barnett, John K. Cowell, Bruce D. Trapp, and Susan M. Staugaitis
Expression of oligodendrocyte progenitor cell antigens by gliomas: Implications for the histogenesis of brain tumors
PNAS, Vol. 96, Issue 18, 10361-10366, August 31, 1999
Abstract | Full Text | Reprint | Links


Gliomatosis Cerebri


Kong DS, Kim MH, Park WY, Suh YL, Lee JI, Park K, Kim JH, Nam DH
The progression of gliomas is associated with cancer stem cell phenotype
Oncol Rep. 2008 Mar;19(3):639-43
 Abstract |
Links | BL 7:5


Medulloblastoma


Blazek ER, Foutch JL, Maki G
Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):1-5. Epub 2006 Nov 2
 Abstract |
Links | BL 7:5

Christopher R. Calabrese, Helen Poppleton, Andrew Davidoff, and Richard J. Gilbertson
The cancer stem cell niche in medulloblastoma
AACR Meeting Abstracts, Apr 2006; 2006: 1325
Abstract | Links | BL 7:2

Li MC, Deng YW, Wu J, Chen FH, Liu JF, Fang JS
Isolation and characterization of brain tumor stem cells in human medulloblastoma
Ai Zheng. 2006 Feb;25(2):241-6
 Abstract |
Links | BL 7:5

Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL.
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Cancer Cell. 2008 Aug 12;14(2):123-34
 Abstract |
Links | BL 7:16

Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang JH, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN.
Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+ Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma
Stem Cells. 2008 Apr 10; [Epub ahead of print]
 Abstract |
Links | BL 7:8

Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ.
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells
Cancer Cell. 2008 Aug 12;14(2):135-45
 Abstract |
Links | BL 7:16


Metastasis


Alysha K. Croker and Alison L. Allan
Cancer Stem Cells: Implications for the progression and treatment of metastatic disease
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Dec-2007, doi: 10.1111/j.1582-4934.2007.00211.x
 Abstract |  Reprint |
Links | BL 7:5

Feng Li, Benjamin Tiede, Joan Massagué, Yibin Kang
Beyond tumorigenesis: cancer stem cells in metastasis
Cell Research 17, 3 - 14 (01 Jan 2007). Published online 19 December 2006
 Abstract |
Links | BL 7:5

Gao JX
Cancer stem cells: the lessons from precancerous stem cells
J Cell Mol Med. 2007 Dec 5; [Epub ahead of print]
 Abstract |  Reprint | Links | BL 7:5

R. R. Langley and I. J. Fidler
Tumor Cell-Organ Microenvironment Interactions in the Pathogenesis of Cancer Metastasis
Endocr. Rev., May 1, 2007; 28(3): 297 - 321
 Abstract |
Links | BL 7:6


Oligoastrocytoma


Yi L, Zhou ZH, Ping YF, Chen JH, Yao XH, Feng H, Lu JY, Wang JM, Bian XW
Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma
Mod Pathol. 2007 Oct;20(10):1061-8. Epub 2007 Jul 27
 Abstract |
 Links | BL 7:5


Ologodendroglioma


Kyuson Yun and Mark A. Israel
Isolation of cancer stem cells from a mouse model of brain tumor
AACR Meeting Abstracts, Apr 2006; 2006: 642
Abstract | Links | BL 7:1


Pediatric Brain Tumors


Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, Kornblum HI
Cancerous stem cells can arise from pediatric brain tumors
PNAS, December 9, 2003, vol. 100 no. 25, 15178-15183
Abstract | Full Text | Reprint
| Links

Komuro H, Saihara R, Shinya M, Takita J, Kaneko S, Kaneko M, Hayashi Y
Identification of side population cells (stem-like cell population) in pediatric solid tumor cell lines
J Pediatr Surg. 2007 Dec;42(12):2040-5
 Abstract |
Links | BL 7:5


Side Population


Chua C, Zaiden N, Chong KH, See SJ, Wong MC, Ang BT, Tang C
Characterization of a side population of astrocytoma cells in response to temozolomide
J Neurosurg. 2008 Nov;109(5):856-66
  Abstract |   Links |   Issue

Harris MA, Yang H, Low BE, Mukherje J, Guha A, Bronson RT, Shultz LD, Israel MA, Yun K
Cancer stem cells are enriched in the side population cells in a mouse model of glioma
Cancer Res. 2008 Dec 15;68(24):10051-9
  Abstract |   Reprint |   Links |   Issue


Stem Cell Niche


Liu JM, Mao BY, Hong S, Liu YH, Wang XJ
The postoperative brain tumour stem cell (BTSC) niche and cancer recurrence
Adv Ther. 2008 May 7; [Epub ahead of print]
 Abstract |
Links | BL 7:10

Jones DL, Wagers AJ
No place like home: anatomy and function of the stem cell niche
Nat Rev Mol Cell Biol. 2008 Jan;9(1):11-21
Abstract | Links | BL 7:1

Linheng Li and William B. Neaves
Normal Stem Cells and Cancer Stem Cells: The Niche Matters
Cancer Research 66, 4553-4557, May 1, 2006
 Abstract |  Full Text |  Reprint |
Links | BL 7:6

Sneddon JB, Werb Z
Location, location, location: the cancer stem cell niche
Cell Stem Cell. 2007 Dec 12;1(6):607-11
 Abstract |
Links | BL 7:8

Wu YY, Huang Q, Dong J, Lan Q
Correlation of stem cell niche to genesis and development of tumor stem cells
Ai Zheng. 2008 Jan;27(1):109-12
Abstract |  Links | BL 7:2

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