Etiology and Pathogenesis > Genetic Alterations


CNS Tumors


Lee H, Kong SW, Park PJ
Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes
Bioinformatics. 2008 Feb 8; [Epub ahead of print]
 Abstract |  DBLinks | BL 7:4


Glioblastoma


Hulleman E, Quarto M, Vernell R, Masserdotti G, Colli E, Kros JM, Levi D, Gaetani P, Tunici P, Finocchiaro G, Rodriguez Y Baena R, Capra M, Helin K.
A role for the transcription factor HEY1 in glioblastoma
J Cell Mol Med. 2008 Mar 17; [Epub ahead of print]
 Abstract |  Reprint |
DBLinks | BL 7:7

Kavsan VM, Dmitrenko VV, Shostak KO, Bukreieva TV, Vitak NY, Simirenko OE, Malisheva TA, Shamayev MI, Rozumenko VD, Zozulya YA.
Comparison of microarray and sage techniques in gene expression analysis of human glioblastoma.
Tsitol Genet. 2007 Jan-Feb;41(1):36-55.
PMID: 17427416 [PubMed - in process]

Lo KC, Bailey D, Burkhardt T, Gardina P, Turpaz Y, Cowell JK
Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization
Genes Chromosomes Cancer. 2007 Nov 29;. [Epub ahead of print]
Abstract | DBLinks

Ramon Martinez, Gabriele Schackert and Manel Esteller
Hypermethylation of the proapoptotic gene TMS1/ASC: prognostic importance in glioblastoma multiforme
J Neurooncol. 2006 Oct 18; [Epub ahead of print]
Abstract

Stéphan Saikali, Tony Avril, Brigitte Collet, Abderrahmane Hamlat, Jean-Yves Bansard, Bernard Drenou, Yvon Guegan and Véronique Quillien 
Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Rα2, gp100 and TRP-2 for immunotherapy
J Neurooncol. 2006 Sep 27; [Epub ahead of print]
Abstract

Wang LF, Fokas E, Juricko J, You A, Rose F, Pagenstecher A, Engenhart-Cabillic R, An HX.
Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients
BMC Cancer. 2008 Mar 25;8(1):79
 Abstract |  Full Text |  Reprint |
DBLinks | BL 7:7


Gliomas


De Witt Hamer PC, Van Tilborg AA, Eijk PP, Sminia P, Troost D, Van Noorden CJ, Ylstra B, Leenstra S.
The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids.
Oncogene. 2007 Oct 15; [Epub ahead of print]
Abstract

Batistatou A, Kyzas PA, Goussia A, Arkoumani E, Voulgaris S, Polyzoidis K, Agnantis NJ, Stefanou D.
Estrogen receptor beta (ERbeta) protein expression correlates with BAG-1 and prognosis in brain glial tumours.
J Neurooncol. 2006 Mar;77(1):17-23. Epub 2005 Nov 15.
Abstract


Gliomas (High-grade)


Arifin MT, Hama S, Kajiwara Y, Sugiyama K, Saito T, Matsuura S, Yamasaki F, Arita K, Kurisu K.
Cytoplasmic, but not nuclear, p16 expression may signal poor prognosis in high-grade astrocytomas.
J Neurooncol. 2006 May;77(3):273-7. Epub 2006 Apr 14.
Abstract

Dehais C, Laigle-Donadey F, Marie Y, Kujas M, Lejeune J, Benouaich-Amiel A, Pedretti M, Polivka M, Xuan KH, Thillet J, Delattre JY, Sanson M.
Prognostic stratification of patients with anaplastic gliomas according to genetic profile.
Cancer. 2006 Sep 19; [Epub ahead of print]
Abstract

Shirahata M, Iwao-Koizumi K, Saito S, Ueno N, Oda M, Hashimoto N, Takahashi JA, Kato K
Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis
Clin Cancer Res. 2007 Dec 15;13(24):7341-56

Abstract | DBLinks | BL 7:2


Gliomas (Low-grade)


Mariani L, Deiana G, Vassella E, Fathi AR, Murtin C, Arnold M, Vajtai I, Weis J, Siegenthaler P, Schobesberger M, Reinert MM.
Loss of Heterozygosity 1p36 and 19q13 Is a Prognostic Factor for Overall Survival in Patients With Diffuse WHO Grade 2 Gliomas Treated Without Chemotherapy.
J Clin Oncol. 2006 Sep 11; [Epub ahead of print]
Abstract

Rorive S, Maris C, Debeir O, Sandras F, Vidaud M, Bieche I, Salmon I, Decaestecker C.
Exploring the distinctive biological characteristics of pilocytic and low-grade diffuse astrocytomas using microarray gene expression profiles.
J Neuropathol Exp Neurol. 2006 Aug;65(8):794-807.
Abstract


Medulloblastoma


De Bortoli M, Castellino RC, Lu XY, Deyo J, Sturla LM, Adesina AM, Perlaky L, Pomeroy SL, Lau CC, Man TK, Rao PH, Kim JY.
Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8.
BMC Cancer. 2006 Sep 12;6(1):223 [Epub ahead of print]
Abstract |
Reprint

K Urbanska, J Trojanek, L Del Valle, M B Eldeen, F Hofmann, C Garcia-Echeverria, K Khalili and K Reiss
Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines
Oncogene. 2006 Oct 2; [Epub ahead of print]
Abstract


Meningioma


Hiroaki Okamoto, Jie Li, Alexander O. Vortmeyer, Howard Jaffe, Youn-Soo Lee, Sven Gläsker, Tae-Sung Sohn, Weifen Zeng, Barbara Ikejiri, Martin A. Proescholdt, Christina Mayer, Robert J. Weil, Edward H. Oldfield and Zhengping Zhuang
Comparative Proteomic Profiles of Meningioma Subtypes
Cancer Res. 2006 Oct 15;66(20):10199-204.
Abstract


Metastatic Tumors


Zohrabian VM, Nandu H, Gulati N, Khitrov G, Zhao C, Mohan A, Demattia J, Braun A, Das K, Murali R, Jhanwar-Uniyal M.
Gene expression profiling of metastatic brain cancer.
Oncol Rep. 2007 Aug;18(2):321-8.
PMID: 17611651 [PubMed - in process]


Neuroblastoma


John M. Maris, M.D., Yael P. Mosse, M.D., Jonathan P. Bradfield, B.S., Cuiping Hou, B.S., Stefano Monni, Ph.D., Richard H. Scott, M.B., B.S., Shahab Asgharzadeh, M.D., Edward F. Attiyeh, M.D., Sharon J. Diskin, Ph.D., Marci Laudenslager, B.S., Cynthia Winter, B.A., Kristina A. Cole, M.D., Ph.D., Joseph T. Glessner, M.S., Cecilia Kim, B.A., Edward C. Frackelton, B.A., Tracy Casalunovo, M.S., Andrew W. Eckert, M.S., Mario Capasso, Ph.D., Eric F. Rappaport, Ph.D., Carmel McConville, Ph.D., Wendy B. London, Ph.D., Robert C. Seeger, M.D., Nazneen Rahman, M.D., Ph.D., Marcella Devoto, Ph.D., Struan F.A. Grant, Ph.D., Hongzhe Li, Ph.D., and Hakon Hakonarson, M.D., Ph.D.
Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma
N Engl J Med, Published at www.nejm.org May 7, 2008 (10.1056/NEJMoa0708698)
 Abstract |  Full Text |  Reprint |  News |
DBLinks | BL 7:10


Oligodendroglioma


Alba A. Brandes, Alicia Tosoni, Giovanna Cavallo, Michele Reni, Enrico Franceschi, Laura Bonaldi, Roberta Bertorelle, Marina Gardiman, Claudio Ghimenton, Paolo Iuzzolino, Annalisa Pession, Valeria Blatt, Mario Ermani
Correlations Between O6-Methylguanine DNA Methyltransferase Promoter Methylation Status, 1p and 19q Deletions, and Response to Temozolomide in Anaplastic and Recurrent Oligodendroglioma: A Prospective GICNO Study
J Clin Oncol. 2006 Oct 10;24(29):4746-53. Epub 2006 Sep 5. DOI: 10.1200/JCO.2006.06.3891


Pediatric Brain Tumors


Jacobs JF, Grauer OM, Brasseur F, Hoogerbrugge PM, Wesseling P, Gidding CE, van de Rakt MW, Figdor CG, Coulie PG, de Vries IJ, Adema GJ
Selective cancer-germline gene expression in pediatric brain tumors
J Neurooncol. 2008 Apr 9; [Epub ahead of print]
 Abstract |  Full Text |  Reprint | Supplemental Data |
DBLinks | BL 7:8


Pilocytic Astrocytoma


Addo-Yobo SO, Straessle J, Anwar A, Donson AM, Kleinschmidt-Demasters BK, Foreman NK.
Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
J Neuropathol Exp Neurol. 2006 Aug;65(8):769-75.
Abstract


Primary CNS Lymphoma


Schwindt H, Akasaka T, Zuhlke-Jenisch R, Hans V, Schaller C, Klapper W, Dyer MJ, Siebert R, Deckert M.
Chromosomal translocations fusing the BCL6 gene to different partner loci are recurrent in primary central nervous system lymphoma and may be associated with aberrant somatic hypermutation or defective class switch recombination.
J Neuropathol Exp Neurol. 2006 Aug;65(8):776-82.
Abstract


PNET


Kampman WA, Kros JM, De Jong TH, Lequin MH
Primitive neuroectodermal tumours (PNETs) located in the spinal canal; the relevance of classification as central or peripheral PNET : case report of a primary spinal PNET occurrence with a critical literature review.

J Neurooncol. 2006 Mar;77(1):65-72. Epub 2005 Nov 15.
Abstract

 

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