|
Astrocytomas
|
|
|
|
Andrews DW, Resnicoff M, Flanders AE, Kenyon
L, Curtis M, Merli G, Baserga R, Iliakis G, Aiken RD
Results of a pilot study involving the
use of an antisense oligodeoxynucleotide directed against the
insulin-like growth factor type I receptor in malignant
astrocytomas
J Clin Oncol. 2001 Apr 15;19(8):2189-200
|
|
Zumkeller W, Saaf M, Rahn T
Insulin-like growth factor (IGF)-I, -II and
IGF-binding proteins in the cyst fluid of a patient with astrocytoma
Childs Nerv Syst. 1993 Apr;9(2):100-3
|
|
|
Brain
Tumors
|
|
|
|
Glick
RP, Gettleman R, Patel K, Lakshman R, Tsibris JC
Insulin
and insulin-like growth factor I in brain tumors: binding and in vitro
effects
Neurosurgery. 1989 Jun;24(6):791-7
|
|
Engelhard
HH
Antisense
Oligodeoxynucleotide Technology: Potential Use for the Treatment
of Malignant Brain Tumors
Cancer Control. 1998 Mar;5(2):163-170
|
|
Kurihara
M, Tokunaga Y, Ochi A, Kawaguchi T, Tsutsumi K, Shigematsu K, Niwa M,
Mori K
Expression
of insulin-like growth factor I receptors in human brain tumors:
comparison with epidermal growth factor receptor by using quantitative
autoradiography
No To Shinkei. 1989 Jul;41(7):719-25
|
|
Cheppail Ramachandran, Ziad Khatib,
Athena Pefkarou, John Fort, Hugo B. Fonseca, Steven J. Melnick and Enrique
Escalon
Tamoxifen modulation of etoposide cytotoxicity involves
inhibition of protein kinase C activity and insulin-like growth factor II
expression in brain tumor cells
J Neurooncol. 2004 Mar-Apr;67(1-2):19-28. (Abstract+)
|
|
Yokoyama
S, Hirano H, Wakimaru N, Sarker KP, Kuratsu J
Inhibitory
effect of epigallocatechin-gallate on brain tumor cell lines in vitro
Neuro-oncol. 2001 Jan;3(1):22-8
|
|
|
Glioblastoma
|
|
|
|
Ambrose
D, Resnicoff M, Coppola D, Sell C, Miura M, Jameson S, Baserga R,
Rubin R
Growth
regulation of human glioblastoma T98G cells by insulin-like growth
factor-1 and its receptor
J Cell Physiol. 1994 Apr;159(1):92-100
|
|
Daniel
J. Brat, Amilcar Castellano-Sanchez, Stephen B. Hunter, Marcia Pecot,
Cynthia Cohen, Elizabeth H. Hammond, Balveen Kaur, and Erwin G. Van Meir
Pseudopalisading Cells In
Glioblastoma Are Hypoxic And Could Represent A Rapidly Migrating Population
Society for Neuro-Oncology Eighth Annual Meeting. Keystone, Colorado. November
13–16, 2003. Abstract No. AN-03.
Neuro-Oncology, Volume 5, Issue 4, October 2003
|
|
Marc
A. Brockmann, Ulrike Ulbricht, Regina Fillbrandt, Manfred Westphal,
and Katrin Lamszus
Stimulation
Of Glioblastoma And Cerebral Microvascular Endothelial Cell Migration By
Tumor-Associated Growth Factors
Society for
Neuro-Oncology Eighth Annual Meeting. Keystone, Colorado. November
13–16, 2003. Abstract No. AN-04.
Neuro-Oncology, Volume 5, Issue 4, October 2003
|
|
Brockmann MA, Ulbricht U, Gruner K,
Fillbrandt R, Westphal M, Lamszus K
Glioblastoma and cerebral microvascular
endothelial cell migration in response to tumor-associated growth factors
Neurosurgery. 2003 Jun;52(6):1391-9; discussion 1399
|
|
Burgaud
JL, Resnicoff M, Baserga R
Mutant
IGF-I receptors as dominant negatives for growth and transformation
Biochem Biophys Res Commun. 1995 Sep 14;214(2):475-81
|
|
Chakravarti A, Loeffler JS, Dyson NJ
Insulin-like growth factor receptor I mediates
resistance to anti-epidermal growth factor receptor therapy in primary human
glioblastoma cells through continued activation of phosphoinositide 3-kinase
signaling
Cancer Res 2002 Jan 1;62(1):200-7
|
|
Fabry M, Cabrele C, Hocker H, Beck-Sickinger AG
Differently
labeled peptide ligands for rapid investigation of receptor expression on
a new human glioblastoma cell line
Peptides. 2000
Dec;21(12):1885-93
|
|
|
Fukushima
T, Kataoka H.
Roles of insulin-like growth factor binding protein-2
(IGFBP-2) in glioblastoma.
Anticancer Res.
2007 Nov-Dec;27(6A):3685-92.
Abstract
|
|
Gillaspy GE, Mapstone TB, Samols D,
Goldthwait DA
Transcriptional patterns of growth factors and
proto-oncogenes in human glioblastomas and normal glial cells
Cancer Lett. 1992 Jul 31;65(1):55-60
|
|
Kunwar S, Pai LH, Pastan I
Cytotoxicity and antitumor effects of growth
factor-toxin fusion proteins on human glioblastoma multiforme cells
J Neurosurg. 1993 Oct;79(4):569-76
|
|
McCusker
RH, Camacho-Hubner C, Bayne ML, Cascieri MA, Clemmons DR
Insulin-like
growth factor (IGF) binding to human fibroblast and glioblastoma cells:
the modulating effect of cell released IGF binding proteins (IGFBPs)
J Cell Physiol. 1990 Aug;144(2):244-53
|
|
Melino G, Stephanou A,
Annicchiarico-Petruzzelli M, Finazzi-Agro A, Knight RA, Lightman SL
IGF-II
mRNA expression in LI human glioblastoma cell line parallels cell growth
Neurosci Lett. 1992 Sep 14;144(1-2):25-8
|
|
Morash
B, Johnstone J, Leopold C, Li A, Murphy P, Ur E, Wilkinson M
The
regulation of leptin gene expression in the C6 glioblastoma cell line
Mol Cell Endocrinol. 2000 Jul 25;165(1-2):97-105
|
|
Resnicoff
M, Tjuvajev J, Rotman HL, Abraham D, Curtis M, Aiken R, Baserga R
Regression
of C6 rat brain tumors by cells expressing an antisense insulin-like
growth factor I receptor RNA
J Exp Ther Oncol. 1996
Nov;1(6):385-9
|
|
Resnicoff M, Rubini M, Baserga R,
Rubin R
Ethanol inhibits insulin-like growth
factor-1-mediated signalling and proliferation of C6 rat glioblastoma
cells
Lab Invest. 1994 Nov;71(5):657-62
|
|
Resnicoff M, Sell C, Rubini M, Coppola
D, Ambrose D, Baserga R, Rubin R
Rat glioblastoma cells expressing an
antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are
nontumorigenic and induce regression of wild-type tumors
Cancer Res. 1994 Apr 15;54(8):2218-22
|
|
Rininsland
F, Johnson TR, Chernicky CL, Schulze E, Burfeind P, Ilan J
Suppression
of insulin-like growth factor type I receptor by a triple-helix strategy
inhibits IGF-I transcription and tumorigenic potential of rat C6
glioblastoma cells
Proc Natl Acad Sci U S A. 1997 May 27;94(11):5854-9 (PDF Full Text)
|
|
Sara
VR, Prisell P, Sjogren B, Persson L, Boethius J, Enberg G
Enhancement
of insulin-like growth factor 2 receptors in glioblastoma
Cancer Lett. 1986 Sep;32(3):229-34
|
|
Savarese A, Annicchiarico-Petruzzelli
M, Citro G, Zupi G, Spagnoli LG, Colantoni A, Vernole P, Stephanou A,
Knight RA, Guerrieri P, et al
Characterisation
of a human glioblastoma cell line (LI) expressing hypothalamic and
pituitary hormones
Exp Brain Res. 1992;89(2):408-14
|
|
Shevelev A, Burfeind P, Schulze E, Rininsland F,
Johnson TR, Trojan J, Chernicky CL, Helene C, Ilan J, Ilan J
Potential triple helix-mediated inhibition of
IGF-I gene expression significantly reduces tumorigenicity of glioblastoma
in an animal model
Cancer Gene Ther. 1997 Mar-Apr;4(2):105-12)
|
|
Toms SA, Hercbergs A, Liu J, Kondo S,
Haqqi T, Casey G, Iwasaki K, Barnett GH, Barna BP
Antagonist effect of insulin-like growth factor I
on protein kinase inhibitor-mediated apoptosis in human glioblastoma cells
in association with bcl-2 and bcl-xL
J Neurosurg. 1998 May;88(5):884-9
|
|
Trojan J, Johnson TR, Rudin SD, Ilan
J, Tykocinski ML, Ilan J
Treatment and prevention of rat glioblastoma by
immunogenic C6 cells expressing antisense insulin-like growth factor I RNA
Science. 1993 Jan 1;259(5091):94-7
|
|
Trojan J, Blossey BK, Johnson TR, Rudin SD,
Tykocinski M, Ilan J, Ilan J
Loss of tumorigenicity of rat glioblastoma
directed by episome-based antisense cDNA transcription of insulin-like
growth factor I
Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4874-8 (PDF Full Text)
|
|
Wang H, Wang H, Shen W, Huang H, Hu L, Ramdas L,
Zhou YH, Liao WS, Fuller GN, Zhang W
Insulin-like growth factor binding protein 2
enhances glioblastoma invasion by activating invasion-enhancing genes
Cancer Res. 2003 Aug 1;63(15):4315-21 (PDF Full Text)
|
|
Wongkajornsilp
A, Ouyprasertkul M, Sangruchi T, Huabprasert S, Pan Y, Tisavipat N,
Chanyavanich V, Sangruchi S, Chomsamut K, Anthony DD
The
analysis of peri-tumor necrosis following the subcutaneous implantation of
autologous tumor cells transfected with an episome transcribing an
antisense insulin-like growth factor 1 RNA in a glioblastoma multiforme
subject
J Med Assoc Thai. 2001 Dec;84 Suppl 3:S740-7
|
|
Zhang W, Wang H, Song SW, Fuller GN
Insulin-like
growth factor binding protein 2: gene expression microarrays and
the hypothesis-generation paradigm
Brain Pathol. 2002
Jan;12(1):87-94 (PDF Full Text)
|
|
Zundel
W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk
AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ
Loss
of PTEN facilitates HIF-1-mediated gene expression
Genes Dev. 2000 Feb 15;14(4):391-6 (PDF Full Text)
|
|
|
Gliomas
|
|
|
|
Hercbergs AA, Goyal LK, Suh JH, Lee S, Reddy CA, Cohen BH,
Stevens GH, Reddy SK, Peereboom DM, Elson PJ, Gupta MK, Barnett GH
Propylthiouracil-induced
chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent
high grade glioma: a phase I/II study
Anticancer Res. 2003 Jan-Feb;23(1B):617-26
|
|
Ly
A, Duc HT, Kalamarides M, Trojan LA, Pan Y, Shevelev A, Francois JC,
Noel T, Kane A, Henin D, Anthony DD, Trojan J
Human glioma
cells transformed by IGF-I triple helix technology show immune and
apoptotic characteristics determining cell selection for gene therapy of
glioblastoma
Mol Pathol. 2001 Aug;54(4):230-9
|
|
Sandberg AC, Engberg C, Lake M, von Holst H, Sara VR
The expression of insulin-like growth factor I
and insulin-like growth factor II genes in the human fetal and adult brain
and in glioma
Neurosci Lett. 1988 Oct 31;93(1):114-9
|
|
|
Cancer
Research
|
|
|
|
Baserga
R
The
contradictions of the insulin-like growth factor 1 receptor
Oncogene. 2000 Nov 20;19(49):5574-81
|
|
Baserga R,
Morrione A
Differentiation
and malignant transformation: two roads diverged in a wood
J Cell Biochem. 1999;Suppl 32-33:68-75
|
|
Baserga R
The
IGF-I receptor in cancer research
Exp Cell Res. 1999
Nov 25;253(1):1-6
|
|
Clarke K, Smith K, Gullick WJ, Harris AL
Mutant epidermal growth factor receptor enhances
induction of vascular endothelial growth factor by hypoxia and
insulin-like growth factor-1 via a PI3 kinase dependent pathway
Br J Cancer. 2001 May 18;84(10):1322-9
|
|
Morrione A, Romano G, Navarro M, Reiss
K, Valentinis B, Dews M, Eves E, Rosner MR, Baserga R
Insulin-like
growth factor I receptor signaling in differentiation of neuronal H19-7
cells
Cancer Res. 2000 Apr 15;60(8):2263-72 (PDF Full Text)
|
|
Resnicoff M, Cui S, Coppola D, Hoek
JB, Rubin R
Ethanol-induced inhibition of cell
proliferation is modulated by insulin-like growth factor-I receptor levels
Alcohol Clin Exp Res. 1996 Aug;20(5):961-6
|
|
|
Meningioma
|
|
|
|
Hultberg
BM, Haselbacher G, Nielsen FC, Wulff BS, Gammeltoft S
Gene
expression of insulin-like growth factor II in human intracranial
meningioma
Cancer. 1993 Dec 1;72(11):3282-6
|
|
|
Non-Nervous
System Tumors
|
|
|
|
Baffa
R, Reiss K, El-Gabry EA, Sedor J, Moy ML, Shupp-Byrne D, Strup SE,
Hauck WW, Baserga R, Gomella LG
Low serum
insulin-like growth factor 1 (IGF-1): a significant association with
prostate cancer
Tech Urol. 2000 Sep;6(3):236-9
|
|
Jianmin Chen, P. Mark Stavro,
Lilian U. Thompson
Dietary Flaxseed Inhibits Human Breast Cancer Growth and
Metastasis and Downregulates Expression of Insulin-Like Growth Factor and
Epidermal Growth Factor Receptor
Nutrition and Cancer, Volume: 43 Number: 2 Page: 187 -- 192 (2002)
|
|
Singh
RP, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R
Dietary
feeding of silibinin inhibits advanced human prostate carcinoma growth
in athymic nude mice and increases plasma insulin-like growth
factor-binding protein-3 levels
Cancer Res. 2002 Jun 1;62(11):3063-9
|
|
|
Tumors
|
|
|
|
Karas M, Amir H, Fishman D, Danilenko M, Segal S, Nahum A,
Koifmann A, Giat Y, Levy J, Sharoni Y
Lycopene
interferes with cell cycle progression and insulin-like growth factor I
signaling in mammary cancer cells
Nutr Cancer. 2000;36(1):101-11
|
|
Peretz
S, Kim C, Rockwell S, Baserga R, Glazer PM
IGF1
receptor expression protects against microenvironmental stress found in the
solid tumor
Radiat Res.
2002 Aug;158(2):174-80
|
|
Reiss
K, D'Ambrosio C, Tu X, Tu C, Baserga R
Inhibition
of tumor growth by a dominant negative mutant of the insulin-like growth
factor I receptor with a bystander effect
Clin
Cancer Res. 1998 Nov;4(11):2647-55
|
|
Rubini M, D'Ambrosio C, Carturan S,
Yumet G, Catalano E, Shan S, Huang Z, Criscuolo M, Pifferi M, Baserga R
Characterization
of an antibody that can detect an activated IGF-I receptor in human
cancers
Exp Cell Res. 1999 Aug 25;251(1):22-32
|
|
