BRAINLIFE Brain Tumor Medical Database

Tumorigenesis

Home > Database > Etiology and Pathogenesis > Tumorigenesis

Contents



Astrocytoma


Addo-Yobo SO, Straessle J, Anwar A, Donson AM, Kleinschmidt-Demasters BK, Foreman NK.
Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
J Neuropathol Exp Neurol. 2006 Aug;65(8):769-75.
  Abstract

Chow LM, Endersby R, Zhu X, Rankin S, Qu C, Zhang J, Broniscer A, Ellison DW, Baker SJ.
Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain.
Cancer Cell. 2011 Mar 8;19(3):305-16.
  Abstract |   Reprint |   Related articles


Basic Science


Axelrod R, Axelrod DE, Pienta KJ.
Evolution of cooperation among tumor cells
PNAS | September 5, 2006 | vol. 103 | no. 36 | 13474-13479. Published online before print August 28, 2006
  Abstract |   Full Text |   Reprint

Robert N. Barnett, Angelo Bongiorno, Charles L. Cleveland, Abraham Joy, Uzi Landman, and Gary B. Schuster
Oxidative Damage to DNA: Counterion-Assisted Addition of Water to Ionized DNA
J. Am. Chem. Soc.,128 (33), 10795 -10800, 2006. DOI: 10.1021/ja061795y, Web Release Date: 28 July 2006

Davies PC, Lineweaver CH.
Cancer tumors as Metazoa 1.0: tapping genes of ancient ancestors.
Phys Biol. 2011 Feb 7;8(1):015001. [Epub ahead of print]
  Abstract |   Reprint |   News    News |   Related articles

V M Draviam, I Shapiro, B Aldridge, P K Sorger
Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells
The EMBO Journal (2006) 25, 2814–2827, doi:10.1038/sj.emboj.7601168. Published online 8 June 2006

Dunn EF, Connor JH.
Dominant Inhibition of Akt/PKB signaling by the Matrix protein of a negative-strand RNA virus.
J Virol. 2010 Oct 27. [Epub ahead of print]
  Abstract |   News |   Related articles

Kurian KM.
The impact of neural stem cell biology on CNS carcinogenesis and tumor types.
Patholog Res Int. 2011;2011:685271. Epub 2011 May 19.
  Abstract |   Reprint |   Related articles

Manjari Mazumdar, Ji-Hyeon Lee, Kundan Sengupta, Thomas Ried, Sushil Rane and Tom Misteli
Tumor Formation via Loss of a Molecular Motor Protein
Current Biology, Volume 16, CNO 15, 8 August 2006, Pages 1559-1564, doi:10.1016/j.cub.2006.06.029, Available online 7 August 2006

Vidhya Narayanan, Piotr A. Mieczkowski, Hyun-Min Kim, Thomas D. Petes and Kirill S. Lobachev
The Pattern of Gene Amplification Is Determined by the Chromosomal Location of Hairpin-Capped Breaks
Cell, Vol 125, 1283-1296, 30 June 2006, Available online 29 June 2006, doi:10.1016/j.cell.2006.04.042

Yoshimasa Saito, Gangning Liang, Gerda Egger, Jeffrey M. Friedman, Jody C. Chuang, Gerhard A. Coetzee, and Peter A. Jones
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
Cancer Cell, Vol 9, 435-443, 13 June 2006. DOI: 10.1016/j.ccr.2006.04.020. Available online 12 June 2006

Siebzehnrubl FA, Reynolds BA, Vescovi A, Steindler DA, Deleyrolle LP.
The origins of glioma: E Pluribus Unum?
Glia. 2011 Feb 23;. [Epub ahead of print]
  Abstract |   Related articles

Torquato S.
Toward an Ising model of cancer and beyond.
Phys Biol. 2011 Feb 7;8(1):015017. [Epub ahead of print]
  Abstract |   Reprint |   Related articles


Brain Tumors


Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A
Analysis of the IDH1 codon 132 mutation in brain tumors
Acta Neuropathol. 2008 Dec;116(6):597-602. Epub 2008 Nov 5
  Abstract |   Full Text |   Reprint

Jacques TS, Swales A, Brzozowski MJ, Henriquez NV, Linehan JM, Mirzadeh Z, O' Malley C, Naumann H, Alvarez-Buylla A, Brandner S
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes.
EMBO J. 2009 Nov 19. [Epub ahead of print]
  Abstract

Janic A, Mendizabal L, Llamazares S, Rossell D, Gonzalez C.
Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila
Science 24 December 2010: 1824-1827. [DOI:10.1126/science.1195481]
  Abstract |   News   News


Kofman A, Marcinkiewicz L, Dupart E, Lyshchev A, Martynov B, Ryndin A, Kotelevskaya E, Brown J, Schiff D, Abounader R.
The roles of viruses in brain tumor initiation and oncomodulation.
J Neurooncol. 2011 Jul 1. [Epub ahead of print]
  Abstract |   Related articles

Mimeault M, Batra SK.
Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: Pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies.
Brain Pathol. 2011 May 26;. [Epub ahead of print]
  Abstract |   Related articles


Moroni I, Bugiani M, D'Incerti L, Maccagnano C, Rimoldi M, Bissola L, Pollo B, Finocchiaro G, Uziel G
L-2-hydroxyglutaric aciduria and brain malignant tumors: a predisposing condition?
Neurology. 2004 May 25;62(10):1882-4

Alan H. Shih, Eric C. Holland
Developmental neurobiology and the origin of brain tumors
J Neurooncol, 70(2):125-135, November 2004. (Abstract+)

Swartling JF
Identifying candidate genes involved in brain tumor formation
Ups J Med Sci. 2008;113(1):32-71.Epub 2007 Dec 6
Abstract | Reprint

Darius Widera, Aljoscha Kaus, Christian Kaltschmidt and Barbara Kaltschmidt
Neural stem cells, inflammation and NF-κB: basic principle of maintenance and repair or origin of brain tumours?
J Cell Mol Med., OnlineAccepted Articles, Accepted article online: 20-Dec-2007, doi: 10.1111/j.1582-4934.2007.00208.x
 Abstract |  Reprint


Cancer Research


Takahiro Maeda, Robin M. Hobbs, Taha Merghoub, Ilhem Guernah, Arthur Zelent, Carlos Cordon-Cardo, Julie Teruya-Feldstein & Pier Paolo Pandolfi
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
Nature 433, 278 - 285 (20 January 2005)

Adnan Z. Rizvi, John R. Swain, Paige S. Davies, Alexis S. Bailey, Adria D. Decker, Holger Willenbring, Markus Grompe, William H. Fleming, and Melissa H. Wong
Bone marrow-derived cells fuse with normal and transformed intestinal stem cells
PNAS, April 18, 2006, vol. 103, no. 16, 6321-6325; Published online before print April 10, 2006; DOI: 10.1073/pnas.0508593103
Abstract | Full Text | Reprint | News

Stefano Volinia, George A. Calin, Chang-Gong Liu, Stefan Ambs, Amelia Cimmino, Fabio Petrocca, Rosa Visone, Marilena Iorio, Claudia Roldo, Manuela Ferracin, Robyn L. Prueitt, Nozumu Yanaihara, Giovanni Lanza, Aldo Scarpa, Andrea Vecchione, Massimo Negrini, Curtis C. Harris, and Carlo M. Croce
A microRNA expression signature of human solid tumors defines cancer gene targets
Proc. Natl. Acad. Sci. USA, Published online before print February 3, 2006
Abstract | News News


Ependymoma


Blanca Suarez-Merino, Mike Hubank, Tamas Revesz, William Harkness, Richard Hayward, Dominic Thompson, John L. Darling, David G.T. Thomas, and Tracy J. Warr
Microarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3
Neuro-Oncology, Volume 7, Number 1, Pages 20 -- 31, January 2005. (Abstract+)

Hallacq P, Labrousse F, Streichenberger N, Lisii D, Fischer G
Bifocal myxopapillary ependymoma of the terminal filum: the end of a spectrum? Case report
J Neurosurg. 2003 Apr;98(3 Suppl):288-9.


Glioblastoma


Bohman LE, Swanson KR, Moore JL, Rockne R, Mandigo C, Hankinson T, Assanah M, Canoll P, Bruce JN.
Magnetic Resonance Imaging Characteristics of Glioblastoma Multiforme: Implications for Understanding Glioma Ontogeny.
Neurosurgery. 2010 Sep 23. [Epub ahead of print]
  Abstract |   Related articles

Bonavia R, Inda MD, Cavenee WK, Furnari FB.
Heterogeneity maintenance in glioblastoma: a social network.
Cancer Res. 2011 Jun 15;71(12):4055-60. Epub 2011 May 31.
  Abstract |   Related articles

Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, James CD, VandenBerg SR, Costello JF, Moorefield S, Cowdrey CJ, Prados M, Phillips HS.
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
Cancer Cell. 2010 Apr 13;17(4):362-75
  Abstract

Chirasani SR, Sternjak A, Wend P, Momma S, Campos B, Herrmann IM, Graf D, Mitsiadis T, Herold-Mende C, Besser D, Synowitz M, Kettenmann H, Glass R
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells
Brain. 2010 May 30;. [Epub ahead of print]
  Abstract

Deangelis LM, Mellinghoff IK.
Virchow 2011 or How to ID(H) Human Glioblastoma.
J Clin Oncol. 2011 Oct 24;. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Deleyrolle LP, Harding A, Cato K, Siebzehnrubl FA, Rahman M, Azari H, Olson S, Gabrielli B, Osborne G, Vescovi A, Reynolds BA.
Evidence for label-retaining tumour-initiating cells in human glioblastoma.
Brain. 2011 Apr 22;. [Epub ahead of print]
  Abstract |   Related articles

Dziurzynski K, Wei J, Qiao W, Hatiboglu MA, Kong LY, Wu A, Wang Y, Cahill D, Levine NB, Prabhu S, Rao G, Sawaya R, Heimberger AB.
Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype.
Clin Cancer Res. 2011 Apr 13. [Epub ahead of print]
  Abstract |   Related articles

Caroline Gregorian, Matthias Groszer, Qing Yue, Xin Liu, Hong Wu
The Role of PTEN Tumor Suppressor in Brain Growth and Tumor Development
96th AACR Annual Meeting, Anaheim/Orange County, CA, April 16-20, 2005
Proc Amer Assoc Cancer Res 2005;46:
Abstract No.2075

Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
Nat Genet. 2000 May;25(1):55-7


Hsieh D, Hsieh A, Ellsworth R, Stea B
IGFBP2 promotes glioma tumor stem cell expansion and survival
Biochem Biophys Res Commun. 2010 May 29;. [Epub ahead of print]
  Abstract

Jeon HM, Jin X, Lee JS, Oh SY, Sohn YW, Park HJ, Joo KM, Park WY, Nam DH, Depinho RA, Chin L, Kim H.
Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling
Genes Dev. 2008 Aug 1;22(15):2028-33
 Abstract |  Full Text |  Reprint

Jun Kouno, Hisaki Nagai, Takemitsu Nagahata, Masamitsu Onda, Humio Yamaguchi, Koji Adachi, Hiroshi Takahashi, Akira Teramoto, Mitsuru Emi
Up-regulation of CC chemokine, CCL3L1, and receptors, CCR3, CCR5 in human glioblastoma that promotes cell growth
Journal of Neuro-Oncology, 70(3): 301-307, December 2004. (Abstract+)

Kroonen J, Nguyen-Khac MT, Deprez M, Rogister B, Robe P.
Glioblastoma, an example of translational research?
Rev Med Liege. 2008 May-Jun;63(5-6):251-6
 Abstract

Jeffrey C. Lee, Igor Vivanco, Rameen Beroukhim, Julie H. Y. Huang, Whei L. Feng, Ralph M. DeBiasi, Koji Yoshimoto, Jennifer C. King, Phioanh Nghiemphu, Yuki Yuza, Qing Xu, Heidi Greulich, Roman K. Thomas, J. Guillermo Paez, Timothy C. Peck, David J. Linhart, Karen A. Glatt1, Gad Getz, Robert Onofrio, Liuda Ziaugra, Ross L. Levine, Stacey Gabriel, Tomohiro Kawaguchi, Keith O'Neill, Haumith Khan, Linda M. Liau, Stanley F. Nelson, P. Nagesh Rao, Paul Mischel, Russell O. Pieper, Tim Cloughesy, Daniel J. Leahy, William R. Sellers, Charles L. Sawyers, Matthew Meyerson, Ingo K. Mellinghoff
Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain
PLoS Medicine Vol. 3, No. 12, e485; doi:10.1371/journal.pmed.0030485; December 19, 2006

Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang Z, Aldape KD, Mischel PS, Liau LM, Escovedo CJ, Chen W, Nghiemphu PL, James CD, Prados MD, Westphal M, Lamszus K, Cloughesy T, Phillips HS.
Evidence for Sequenced Molecular Evolution of IDH1 Mutant Glioblastoma From a Distinct Cell of Origin.
J Clin Oncol. 2011 Oct 24;. [Epub ahead of print]
  Abstract |   Related articles

Mangiola A, Anile C, Pompucci A, Capone G, Rigante L, De Bonis P.
Glioblastoma therapy: going beyond Hercules Columns.
Expert Rev Neurother. 2010 Apr;10(4):507-14.
  Abstract |   Full text |   Related articles

Nishide K, Nakatani Y, Kiyonari H, Kondo T
Glioblastoma formation from cell population depleted of Prominin1-expressing cells
PLoS One. 2009 Aug 31;4(8):e6869°
  Abstract |   Full Text |   Reprint

Ohgaki H, Kleihues P
Genetic alterations and signaling pathways in the evolution of gliomas
Cancer Sci. 2009 Aug 6;. [Epub ahead of print]
  Abstract |   Full Text |   Reprint

Strååt K, Liu C, Rahbar A, Zhu Q, Liu L, Wolmer-Solberg N, Lou F, Liu Z, Shen J, Jia J, Kyo S, Björkholm M, Sjöberg J, Söderberg-Nauclér C, Xu D
Activation of telomerase by human cytomegalovirus
J Natl Cancer Inst. 2009 Apr 1;101(7):488-97. Epub 2009 Mar 24
  Abstract

EGFR


Mazzoleni S, Politi LS, Pala M, Cominelli M, Franzin A, Sergi Sergi L, Falini A, De Palma M, Bulfone A, Poliani PL, Galli R.
Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
Cancer Res. 2010 Sep 21;. [Epub ahead of print]
  Abstract |   Full Text |   Reprint |   Related articles


Gliomas


Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A & Iavarone A
The transcriptional network for mesenchymal transformation of brain tumours
Nature advance online publication 23 December 2009
  Abstract |   News   News

Diabira S, Morandi X.
Gliomagenesis and neural stem cells: Key role of hypoxia and concept of tumor "neo-niche"
Med Hypotheses. 2007 Jul 3; [Epub ahead of print]
PMID: 17614215 [PubMed - as supplied by publisher]

Duffau H, Capelle L
Preferential brain locations of low-grade gliomas
Cancer. 2004 Jun 15;100(12):2622-6

Hitoshi Y, Harris BT, Liu H, Popko B, Israel MA
Spinal glioma: platelet-derived growth factor B-mediated oncogenesis in the spinal cord
Cancer Res. 2008 Oct 15;68(20):8507-15
  Abstract

Hong C, Maunakea A, Jun P, Bollen AW, Hodgson JG, Goldenberg DD, Weiss WA, Costello JF
Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8
Cancer Res. 2005 May 1;65(9):3617-23

Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
Glia. 2002 Sep;39(3):193-206. Epub 2002 Jun 11

Abstract

Jones TS, Holland EC.
Standard of care therapy for malignant glioma and its effect on tumor and stromal cells.
Oncogene. 2011 Sep 12. [Epub ahead of print]
  Abstract |   Related articles°

Junier MP, Sharif A.
Instability of cell phenotype and tumor initiating cells in gliomas.
Biol Aujourdhui. 2011;205(1):63-74.
  Abstract |   Related articles

Kan P, Gottfried O, Blumenthal DT, Townsend JJ, Drozd-Borysiuk E, Brothman AR, Jensen RL
Oligodendroglioma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors. Case report with histological and molecular differentiation of the tumors and review of the literature
J Neurosurg. 2004 Apr;100(4):700-5

Li L, Dutra A, Pak E, Labrie Iii JE, Gerstein RM, Pandolfi PP, Recht LD, Ross AH.
EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors
Neuro Oncol. 2008 Sep 23; [Epub ahead of print]
  Abstract

Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H, Foreman O, Bronson RT, Nishiyama A, Luo L, Zong H.
Mosaic analysis with double markers reveals tumor cell of origin in glioma.
Cell. 2011 Jul 22;146(2):209-21. Epub 2011 Jul 7.
  Abstract |   Reprint |   Related articles

Liu HK, Wang Y, Belz T, Bock D, Takacs A, Radlwimmer B, Barbus S, Reifenberger G, Lichter P, Schütz G
The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation
Genes Dev. 2010 Apr 1;24(7):683-95
  Abstract |   Reprint

Moore LM, Holmes KM, Fuller GN, Zhang W.
Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model.
Chin J Cancer. 2011 Mar;30(3):163-72.
  Abstract |   Reprint |   Related articles

Noble M, Mayer-Pröschel M
Growth factors, glia and gliomas
J Neurooncol. 1997 Dec;35(3):193-209
  Abstract |   Reprint

Pong WW, Gutmann DH.
The ecology of brain tumors: lessons learned from neurofibromatosis-1.
Oncogene. 2010 Nov 15. [Epub ahead of print]
  Abstract |
  Related articles

Prestegarden L, Svendsen A, Wang J, Sleire L, Skaftnesmo KO, Bjerkvig R, Yan T, Askland L, Persson A, Sakariassen PO, Enger PO.
Glioma Cell Populations Grouped by Different Cell Type Markers Drive Brain Tumor Growth
Cancer Res. 2010 May 11;. [Epub ahead of print]
  Abstract

David Schiff, Thomas Beebe, Steve Woodle, Roy First, Joseph Buell
Gliomas following organ transplantation: a tumor registry analysis
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No. 303

Shuangshoti S, Hjardermaal GM, Ahmad Y, Arden JL, Herman MM
Concurrence of multiple sclerosis and intracranial glioma. Report of a case and review of the literature
Clin Neuropathol. 2003 Nov-Dec;22(6):304-8

Squatrito M, Holland EC.
DNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistance.
Cancer Res. 2011 Sep 15;71(18):5945-9. Epub 2011 Sep 13.
  Abstract |   Related articles

Sukhdeo K, Hambardzumyan D, Rich JN.
Glioma development: where did it all go wrong?
Cell. 2011 Jul 22;146(2):187-8.
  Abstract |   Reprint |   Related articles

Wang Y, Yang J, Zheng H, Tomasek GJ, Zhang P, McKeever PE, Lee EY, Zhu Y
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
Cancer Cell. 2009 Jun 2;15(6):514-26
  Abstract

Watanabe T, Nobusawa S, Kleihues P, Ohgaki H
IDH1 Mutations Are Early Events in the Development of Astrocytomas and Oligodendrogliomas
Am J Pathol. 2009 Feb 26. [Epub ahead of print]
  Abstract

Westermark B, Heldin CH, Nistér M
Platelet-derived growth factor in human glioma
Glia. 1995 Nov;15(3):257-63
  Abstract

Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, Velculescu VE, Vogelstein B, Bigner DD.
IDH1 and IDH2 mutations in gliomas
N Engl J Med. 2009 Feb 19;360(8):765-73
  Abstract


Gliomas (High-Grade)


Jones TS, Holland EC.
Molecular Pathogenesis of Malignant Glial Tumors.
Toxicol Pathol. 2010 Nov 15;. [Epub ahead of print]
  Abstract |   Related articles


Medulloblastoma


Binning MJ, Niazi T, Pedone CA, Lal B, Eberhart CG, Kim KJ, Laterra J, Fults DW.
Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth
Cancer Res. 2008 Oct 1;68(19):7838-45
 Abstract

E Ferretti, L Di Marcotullio, M Gessi, T Mattei, A Greco, A Po, E De Smaele, F Giangaspero, R Riccardi, C Di Rocco, S Pazzaglia, M Maroder, M Alimandi, I Screpanti and A Gulino
Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets
Oncogene advance online publication 31 July 2006; doi: 10.1038/sj.onc.1209716

Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ.
Subtypes of medulloblastoma have distinct developmental origins.
Nature. 2010 Dec 23;468(7327):1095-9. Epub 2010 Dec 8.
  Abstract |   News |   Related articles

Lindsey JC, Anderton JA, Lusher ME, Clifford SC.
Epigenetic events in medulloblastoma development.
Neurosurg Focus. 2005 Nov 15;19(5):E10.
  Abstract |   Reprint |
  Related articles

Marino S.
Medulloblastoma: developmental mechanisms out of control.
Trends Mol Med. 2005 Jan;11(1):17-22. Epub 2004 Dec 15.
  Abstract |   Related articles

Polkinghorn WR, Tarbell NJ
Medulloblastoma: Tumorigenesis, Current Clinical Paradigm, and Efforts to Improve Risk Stratification
Nat Clin Pract Oncol. 2007 May; 4(5):295-304
  Abstract |   Full Text |   Related articles

Roussel MF, Hatten ME.
Cerebellum development and medulloblastoma.
Curr Top Dev Biol. 2011;94:235-82.
  Abstract |   Related articles

Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL.
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Cancer Cell. 2008 Aug 12;14(2):123-34
 Abstract

Tong CY, Hui AB, Yin XL, Pang JC, Zhu XL, Poon WS, Ng HK
Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization
J Neurosurg. 2004 Feb;100(2 Suppl):187-93

Vulcani-Freitas TM, Saba-Silva N, Cappellano A, Cavalheiro S, Marie SK, Oba-Shinjo SM, Malheiros SM, de Toledo SR
ASPM gene expression in medulloblastoma
Childs Nerv Syst. 2010 Aug 6;. [Epub ahead of print]
  Abstract

Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ.
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells
Cancer Cell. 2008 Aug 12;14(2):135-45
 Abstract


Meningioma


Katariina Korhonen, Tiina Salminen, Jani Raitanen, Anssi Auvinen, Jorma Isola and Hannu Haapasalo
Female predominance in meningiomas can not be explained by differences in progesterone, estrogen, or androgen receptor expression
J Neurooncol. 2006 May 13; [Epub ahead of print]; DOI: 10.1007/s11060-006-9146-9
Abstract

Ohba S, Yoshida K, Hirose Y, Ikeda E, Kawase T
Meningioma of the cerebellopontine angle in identical twins: a case report
J Neurooncol. Published online: 13 December 2009 [Epub ahead of print]
  Abstract |   Full Text |   Reprint

Pereira EA, Dabbous B, Qureshi HU, Ansorge O, Bojanic S
Rapid development of glioblastoma at the site of atypical meningioma resection
Br J Neurosurg. 2010 Aug;24(4):471-3
  Abstract


Neuroesthesioblastoma


Casalbore P, Budoni M, Ricci-Vitiani L, Cenciarelli C, Petrucci G, Milazzo L, Montano N, Tabolacci E, Maira G, Larocca LM, Pallini R.
Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1
PLoS ONE. 2009;4(2):e4434. Epub 2009 Feb 11
  Abstract |   Full Text |   Reprint


Oligodendroglioma


Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
Genes Dev. 2001 Aug 1;15(15):1913-25
  Abstract |   Full Text |   Reprint

Lindberg N, Kastemar M, Olofsson T, Smits A, Uhrbom L
Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma
Oncogene. 2009 May 4. [Epub ahead of print]
  Abstract


Pediatric Patients


Crouse NR, Dahiya S, Gutmann DH.
Rethinking pediatric gliomas as developmental brain abnormalities.
Curr Top Dev Biol. 2011;94:283-308.
  Abstract |   Related articles


This website is certified by Health On the Net Foundation. Click to verify. HOME ARCHIVES OF NEURO-ONCOLOGY CURRENT NEURO-ONCOLOGY NEWS CLINICAL NEURO-ONCOLOGY LIBRARY
DATABASE: Classification | Diagnosis | Epidemiology | Etiology & Pathogenesis | Integrative Medicine | Overall Management | Prognosis | Psychosocial Aspects | Stem Cells | Treatment
SERVICES
: About BrainLife | Children's Corner | E-mail Alerts | Journals | Links |
Motto, Dedication, etc. | Patients & Caregivers | Privacy Policy | Search | SiteMap bottom
This site complies with the HONcode standard for trustworthy health information: verify here