Brain Tumor Reports

Volume 13 Number 12
December 2011

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Deangelis LM, Mellinghoff IK.
Virchow 2011 or How to ID(H) Human Glioblastoma.
J Clin Oncol. 2011 Oct 24;. [Epub ahead of print]
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Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang Z, Aldape KD, Mischel PS, Liau LM, Escovedo CJ, Chen W, Nghiemphu PL, James CD, Prados MD, Westphal M, Lamszus K, Cloughesy T, Phillips HS.
Evidence for Sequenced Molecular Evolution of IDH1 Mutant Glioblastoma From a Distinct Cell of Origin.
J Clin Oncol. 2011 Oct 24;. [Epub ahead of print]
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Gonzalez-Segura A, Morales JM, Gonzalez-Darder JM, Cardona-Marsal R, Lopez-Gines C, Cerda-Nicolas M, Monleon D.
Magnetic resonance microscopy at 14 tesla and correlative histopathology of human brain tumor tissue.
PLoS One. 2011;6(11):e27442.
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Li WB, Tang K, Zhang W, Yan W, You G, Li SW, Zhang L, Huang YJ, Jiang T.
Relationship between magnetic resonance imaging and molecular pathology in patients with glioblastoma multiforme.
Chin Med J (Engl). 2011 Sep;124(17):2589-92.
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Frei P, Poulsen AH, Johansen C, Olsen JH, Steding-Jessen M, Schüz J.
Use of mobile phones and risk of brain tumours: update of Danish cohort study.
BMJ. 2011 Oct 19;343:d6387.
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Etiology & Pathogenesis

Cobbs CS.
Evolving evidence implicates cytomegalovirus as a promoter of malignant glioma pathogenesis.
Herpesviridae. 2011 Oct 26;2(1):10. [Epub ahead of print]
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Pellegatta S, Cuppini L, Finocchiaro G.
Brain cancer immunoediting: novel examples provided by immunotherapy of malignant gliomas.
Expert Rev Anticancer Ther. 2011 Nov;11(11):1759-74.
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Song X, Andrew Allen R, Terence Dunn S, Fung KM, Farmer P, Gandhi S, Ranjan T, Demopoulos A, Symons M, Schulder M, Li JY.
Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma.
Int J Clin Exp Pathol. 2011;4(7):651-60. Epub 2011 Sep 17.
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Utsuki S, Oka H, Miyajima Y, Kijima C, Yasui Y, Fujii K.
Adult cerebellar glioblastoma cases have different characteristics from supratentorial glioblastoma.
Brain Tumor Pathol. 2011 Nov 11;. [Epub ahead of print]
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Integrative Medicine

Scheck AC, Abdelwahab MG, Fenton KE, Stafford P.
The ketogenic diet for the treatment of glioma: Insights from genetic profiling.
Epilepsy Res. 2011 Oct 21;. [Epub ahead of print]
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Overall Management

Brandes AA, Franceschi E, Gorlia T, Wick W, Jacobs AH, Baumert BG, van den Bent M, Weller M, Stupp R.
Appropriate end-points for right results in the age of antiangiogenic agents: Future options for phase II trials in patients with recurrent glioblastoma.
Eur J Cancer. 2011 Nov 23;. [Epub ahead of print]
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Jiao Y, Berman H, Kiehl TR, Torquato S.
Spatial organization and correlations of cell nuclei in brain tumors.
PLoS One. 2011;6(11):e27323. Epub 2011 Nov 16.
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Persano L, Rampazzo E, Della Puppa A, Pistollato F, Basso G.
The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications.
ScientificWorldJournal. 2011;11:1829-41. Epub 2011 Oct 23.
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Johnson DR, O'Neill BP.
Glioblastoma survival in the United States before and during the temozolomide era.
J Neurooncol. 2011 Nov 2;. [Epub ahead of print]
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Stem Cells

Chamberlain MC, Bota DA, Linskey ME, Schwartz PH.
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
Neurology. 2011 Nov 29;77(22):e135-6.
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Matos Rojas IA, Bertholdo D, Castillo M.
Stem cells: implications in the development of brain tumors.
Radiologia. 2011 Nov 23;. [Epub ahead of print]. Spanish
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Laboratory Investigations

Bikfalvi A, Moenner M, Javerzat S, North S, Hagedorn M.
Inhibition of angiogenesis and the angiogenesis/invasion shift.
Biochem Soc Trans. 2011 Dec 1;39(6):1560-4.
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Nieto-Sampedro M, Valle-Argos B, Gómez-Nicola D, Fernández-Mayoralas A, Nieto-Díaz M.
Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
Clin Med Insights Oncol. 2011;5:265-314. Epub 2011 Sep 21.
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Van Nifterik KA, Van den Berg J, Slotman BJ, Lafleur MV, Sminia P, Stalpers LJ.
Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.
J Neurooncol. 2011 Oct 26;. [Epub ahead of print]
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Clinical Investigations

Chinnaiyan P, Chowdhary S, Potthast L, Prabhu A, Tsai YY, Sarcar B, Kahali S, Brem S, Yu HM, Rojiani A, Murtagh R, Pan E.
Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma.
Neuro Oncol. 2011 Oct 25;. [Epub ahead of print]
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Cho DY, Yang WK, Lee HC, Hsu DM, Lin HL, Lin SZ, Chen CC, Harn HJ, Liu CL, Lee WY, Ho LH.
Adjuvant Immunotherapy with Whole-Cell Lysate Dendritic Cells Vaccine for Glioblastoma Multiforme: A Phase II Clinical Trial.
World Neurosurg. 2011 Nov 7;. [Epub ahead of print]
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Finocchiaro G, Pellegatta S.
Immunotherapy for glioma: getting closer to the clinical arena?
Curr Opin Neurol. 2011 Dec;24(6):641-7.
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Friday BB, Anderson SK, Buckner J, Yu C, Giannini C, Geoffroy F, Schwerkoske J, Mazurczak M, Gross H, Pajon E, Jaeckle K, Galanis E.
Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study.
Neuro Oncol. 2011 Nov 16;. [Epub ahead of print]
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Franceschi E, Agati R, Brandes AA.
End points for Phase II trials in recurrent glioblastoma: the cornerstone for a new era.
Expert Rev Anticancer Ther. 2011 Nov;11(11):1713-7.
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Freyschlag CF, Smolczyk DR, Janzen E, Schmieder K, Thomé C, Lohr F, Wenz F, Weiss C, Tuettenberg J, Seiz M.
Prolonged administration of temozolomide in adult patients with anaplastic glioma.
Anticancer Res. 2011 Nov;31(11):3873-7.
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Giglio P, Dhamne M, Hess KR, Gilbert MR, Groves MD, Levin VA, Kang SL, Ictech SE, Liu V, Colman H, Conrad CA, Loghin M, de Groot J, Yung WK, Puduvalli VK.
Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma.
Cancer. 2011 Nov 15;. [Epub ahead of print]
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Lam N, Chambers CR.
Temozolomide plus radiotherapy for glioblastoma in a Canadian province: Efficacy versus effectiveness and the impact of O6-methylguanine-DNA-methyltransferase promoter methylation.
J Oncol Pharm Pract. 2011 Nov 7;. [Epub ahead of print]
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Lorgis V, Maura G, Coppa G, Hassani K, Taillandier L, Chauffert B, Apetoh L, Ladoire S, Ghiringhelli F.
Relation between bevacizumab dose intensity and high-grade glioma survival: a retrospective study in two large cohorts.
J Neurooncol. 2011 Nov 11;. [Epub ahead of print]
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Mason WP, Belanger K, Nicholas G, Vallières I, Mathieu D, Kavan P, Desjardins A, Omuro A, Reymond D.
A phase II study of the Ras-MAPK signaling pathway inhibitor TLN-4601 in patients with glioblastoma at first progression.
J Neurooncol. 2011 Nov 3;. [Epub ahead of print]
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Minniti G, Lanzetta G, Scaringi C, Caporello P, Salvati M, Arcella A, De Sanctis V, Giangaspero F, Enrici RM.
Phase II Study of Short-Course Radiotherapy plus Concomitant and Adjuvant Temozolomide in Elderly Patients with Glioblastoma.
Int J Radiat Oncol Biol Phys. 2011 Nov 11;. [Epub ahead of print]
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Narayana A, Gruber D, Kunnakkat S, Golfinos JG, Parker E, Raza S, Zagzag D, Eagan P, Gruber ML.
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
J Neurosurg. 2011 Oct 28;. [Epub ahead of print]
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Niewald M, Berdel C, Fleckenstein J, Licht N, Ketter R, Rübe C.
Toxicity after radiochemotherapy for glioblastoma using temozolomide - a retrospective evaluation.
Radiat Oncol. 2011 Oct 21;6:141.
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Ohno M, Narita Y, Miyakita Y, Ueno H, Kayama T, Shibui S.
Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide.
Neurol Med Chir (Tokyo). 2011;51(10):728-31. Release Date: October 25, 2011.
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Pouleau HB, Sadeghi N, Balériaux D, Mélot C, De Witte O, Lefranc F.
High levels of cellular proliferation predict pseudoprogression in glioblastoma patients.
Int J Oncol. 2011 Nov 11;. [Epub ahead of print]
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Park KJ, Kano H, Iyer A, Liu X, Niranjan A, Flickinger JC, Lieberman FS, Lunsford LD, Kondziolka D.
Salvage gamma knife stereotactic radiosurgery followed by bevacizumab for recurrent glioblastoma multiforme: a case-control study.
J Neurooncol. 2011 Nov 5;. [Epub ahead of print]
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Reardon DA, Wen PY, Alfred Yung WK, Berk L, Narasimhan N, Turner CD, Clackson T, Rivera VM, Vogelbaum MA.
Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial.
Cancer Chemother Pharmacol. 2011 Oct 30;. [Epub ahead of print]
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Shahar T, Ram Z, Kanner AA.
Convection-enhanced delivery catheter placements for high-grade gliomas: complications and pitfalls.
J Neurooncol. 2011 Nov 4;. [Epub ahead of print]
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Sorensen AG, Emblem KE, Polaskova P, Jennings D, Kim H, Ancukiewicz M, Wang M, Wen PY, Ivy P, Batchelor TT, Jain RK.
Increased Survival of Glioblastoma Patients who Respond to Anti-angiogenic Therapy with Elevated Blood Perfusion.
Cancer Res. 2011 Nov 29. [Epub ahead of print]

Tsien CI, Brown D, Normolle D, Schipper M, Morand P, Junck L, Heth JA, Gomez-Hassan D, Ten-Haken R, Chenevert TL, Cao Y, Lawrence TS.
Concurrent Temozolomide and Dose-Escalated Intensity Modulated Radiation Therapy in Newly Diagnosed Glioblastoma.
Clin Cancer Res. 2011 Nov 7;. [Epub ahead of print]
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White E, Bienemann A, Taylor H, Hopkins K, Cameron A, Gill S.
A phase I trial of carboplatin administered by convection-enhanced delivery to patients with recurrent/progressive glioblastoma multiforme.
Contemp Clin Trials. 2011 Nov 12;. [Epub ahead of print]
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Treatment Overviews

Clarke J, Butowski N, Chang S.
Recent advances in therapy for glioblastoma.
Arch Neurol. 2010 Mar;67(3):279-83.
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