Current Neuro-Oncology

Volume 12 Number 9
30 September 2010

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Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P, Rutka JT, Pfister S, Taylor MD.
Medulloblastoma comprises four distinct molecular variants.
J Clin Oncol. 2010 Sep 7. 2011;29(11):1408-14
. doi: 10.1200/JCO.2009.27.4324. PMID: 20823417. Laboratory investigation.

Chen J, Kesari S, Rooney C, Strack PR, Chen J, Shen H, Wu L, Griffin JD.
Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres.
Genes Cancer. 2010
Sep 27;1(8):822-835. doi: 10.1177/1947601910383564 PMID: 21127729 Laboratory investigation. ˍ

Buonamici S, Williams J, Morrissey M, Wang A, Guo R, Vattay A, Hsiao K, Yuan J, Green J, Ospina B, Yu Q, Ostrom L, Fordjour P, Anderson DL, Monahan JE, Kelleher JF, Peukert S, Pan S, Wu X, Maira SM, García-Echeverría C, Briggs KJ, Watkins DN, Yao YM, Lengauer C, Warmuth M, Sellers WR, Dorsch M.
Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.
Sci Transl Med. 2010 Sep 29;2(51):51ra70
. doi: 10.1126/scitranslmed.3001599. PMID: 20881279. Laboratory investigation.

Chung NG.
High-dose chemotherapy with reduced-dose craniospinal radiotherapy in children with newly diagnosed high-risk brain tumor.
Korean J Hematol. 2010 Sep 30. 2010;45(3):211-2. doi: 10.5045/kjh.2010.45.3.211
PMID: 21120213 Comment.
Kim SY, et al.
Reduced-dose craniospinal radiotherapy followed by high-dose chemotherapy and autologous stem cell rescue for children with newly diagnosed high-risk medulloblastoma or supratentorial primitive neuroectodermal tumor.
Korean J Hematol. 2010 Jun 30. 2010;45(2):120-6. doi: 10.5045/kjh.2010.45.2.120
PMID: 21120191 Clinical study.

Lober R, Sharma S, Bell B, Free A, Figueroa R, Sheils CW, Lee M, Cowell J.
Pediatric primary intramedullary spinal cord glioblastoma.
Rare Tumors. 2010 Sep 30;2(3):e48. doi: 10.4081/rt.2010.e48
PMID: 21139963 Case series.