Current
Neuro-Oncology


Volume 21 Number 12
December 2019


Home > Publications > Current Neuro-Oncology > Volume 21, Year 2019 > Number 12, December


CONTENTS


CENTRAL NERVOUS SYSTEM TUMORS

GLIOMAS
BRAIN STEM GLIOMAS
DIFFUSE MIDLINE GLIOMAS
HIGH-GRADE GLIOMAS
LOW-GRADE GLIOMAS

DIFFUSE ASTROCYTIC AND OLIGODENDROGLIAL TUMORS
GLIOBLASTOMA
GLIOSARCOMA

EMBRYONAL TUMORS
MEDULLOBLASTOMA

METASTATIC TUMORS





CENTRAL NERVOUS SYSTEM TUMORS


Ashwath KG, Aggarwal A, Praneeth K, Singla N, Gupta K.
Neutrophil-to-Lymphocyte Ratio: Can It Be Used as an Adjunct Tool to Predict Histopathological Grade of Brain Tumor?
J Neurosci Rural Pract. 2019 Oct;10(4):648-652. doi: 10.1055/s-0039-3399489. Epub 2019 Dec 11.
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Corti C, Urgesi C, Massimino M, Gandola L, Bardoni A, Poggi G.
Effects of supratentorial and infratentorial tumor location on cognitive functioning of children with brain tumor.
Childs Nerv Syst. 2019 Dec 12. doi: 10.1007/s00381-019-04434-3. [Epub ahead of print]°
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Drewes AM, Møller M, Hertzum-Larsen R, Engholm G, Storm H.
Risk of primary brain tumour after breast cancer.
Endocr Connect. 2019 Dec 1. doi: 10.1530/EC-19-0498. [Epub ahead of print]
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GLIOMAS



BRAIN STEM GLIOMAS



Morais BA, Solla DJF, Matushita H, Teixeira MJ, Monaco BA.
Pediatric intrinsic brainstem lesions: clinical, imaging, histological characterization, and predictors of survival.
Childs Nerv Syst. 2019 Dec 13. doi: 10.1007/s00381-019-04453-0. [Epub ahead of print]
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DIFFUSE MIDLINE GLIOMAS



Giagnacovo M, Antonelli M, Biassoni V, Schiavello E, Warmuth-Metz M, Buttarelli FR, Modena P, Massimino M.
Retrospective analysis on the consistency of MRI features with histological and molecular markers in diffuse intrinsic pontine glioma (DIPG).
Childs Nerv Syst. 2019 Dec 17. doi: 10.1007/s00381-019-04463-y. [Epub ahead of print]
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Hayashi A, Ito E, Omura M, et al.
Hypofractionated radiotherapy in children with diffuse intrinsic pontine glioma
[published online ahead of print, 2019 Nov 30].
Pediatr Int. 2019;10.1111/ped.14070. doi:10.1111/ped.14070.
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Huang RY, Guenette JP.
Non-invasive Diagnosis of H3 K27M Mutant Midline Glioma.
Neuro Oncol. 2019 Dec 20. pii: noz240. doi: 10.1093/neuonc/noz240. [Epub ahead of print]
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Comment on: Su X, et al., Automated Machine Learning Based on Radiomics Features Predicts H3 K27M Mutation in Midline Gliomas of the Brain. Neuro Oncol. 2019 Sep 29. doi: 10.1093/neuonc/noz184. [Epub ahead of print] Source / Similar articles .




Kerezoudis P, Goyal A, Lu VM, Alvi MA, Bydon M, Kizilbash SH, Burns TC.
The role of radiation and chemotherapy in adult patients with high-grade brainstem gliomas: results from the National Cancer Database.
J Neurooncol. 2019 Dec 24. doi: 10.1007/s11060-019-03374-x. [Epub ahead of print]
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Su X, Chen N, Sun H, Liu Y, Yang X, Wang W, Zhang S, Tan Q, Su J, Gong Q, Yue Q.
Automated Machine Learning Based on Radiomics Features Predicts H3 K27M Mutation in Midline Gliomas of the Brain.
Neuro Oncol. 2019 Sep 29. doi: 10.1093/neuonc/noz184. [Epub ahead of print]
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Tinkle CL, Simone B, Chiang J, et al.
Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma
[published online ahead of print, 2019 Nov 27].
Int J Radiat Oncol Biol Phys. 2019;S0360-3016(19)34056-8. doi:10.1016/j.ijrobp.2019.11.020.
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HIGH-GRADE GLIOMAS



Bernstock JD, Alva E, Cohen JL, Lobbous M, Chagoya G, Elsayed GA, Orr BA, Rozzelle C, Rocque B, Blount J, Johnston JM, Li R, Fiveash JB, Dhall G, Reddy AT, Friedman GK.
Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience.
Pediatr Blood Cancer. 2020 Mar;67(3):e28119. doi: 10.1002/pbc.28119. Epub 2019 Dec 18.
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Uckun FM, Qazi S, Hwang L, Trieu VN.
Recurrent or Refractory High-Grade Gliomas Treated by Convection-Enhanced Delivery of a TGFβ2-Targeting RNA Therapeutic: A Post-Hoc Analysis with Long-Term Follow-Up.
Cancers (Basel). 2019;11(12):1892. Published 2019 Nov 28. doi:10.3390/cancers11121892
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LOW-GRADE GLIOMAS



Hargrave DR, Bouffet E, Tabori U, et al.
Efficacy and Safety of Dabrafenib in Pediatric Patients with BRAF V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study.
Clin Cancer Res. 2019;25(24):7303–7311. Published 2019 Dec 15. doi:10.1158/1078-0432.CCR-19-2177
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DIFFUSE ASTROCYTIC AND OLIGODENDROGLIAL TUMORS



GLIOBLASTOMA



Ahn S, Park JS, Jang J, Ahn KJ, Hong YK, Yang SH, Jeun SS.
The association between total lymphocyte count after concomitant chemoradiation and overall survival in patients with newly diagnosed glioblastoma.
J Clin Neurosci. 2019 Dec 13. doi: 10.1016/j.jocn.2019.11.017. [Epub ahead of print]
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Baran O, Kemerdere R, Korkmaz TS, Kayhan A, Tanriverdi T.
Can preoperative neutrophil to lymphocyte, lymphocyte to monocyte, or platelet to lymphocyte ratios differentiate glioblastoma from brain metastasis?
Medicine (Baltimore). 2019 Dec;98(50):e18306. doi: 10.1097/MD.0000000000018306.
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Brenner AJ, Peters KB, Vredenburgh J, Bokstein F, Blumenthal DT, Yust-Katz S, Peretz I, Oberman B, Freedman LS, Ellingson BM, Cloughesy TF, Sher N, Cohen YC, Lowenton-Spier N, Rachmilewitz Minei T, Yakov N, Mendel I, Breitbart E, Wen PY.
Safety and efficacy of VB-111, an anti-cancer gene-therapy, in patients with recurrent glioblastoma: results of a phase I/II study.
Neuro Oncol. 2019 Dec 17. doi: 10.1093/neuonc/noz231. [Epub ahead of print]
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Cloughesy TF, Brenner A, de Groot JF, Butowski NA, Zach L, Campian JL, Ellingson BM, Freedman LS, Cohen YC, Lowenton-Spier N, Rachmilewitz Minei T, Shmueli SF; GLOBE Study Investigators, Wen PY.
A randomized controlled phase III study of VB-111 combined with bevacizumab vs. bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE).
Neuro Oncol. 2019 Dec 17. doi: 10.1093/neuonc/noz232. [Epub ahead of print]
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Gittleman H, Ostrom QT, Stetson LC, Waite K, Hodges TR, Wright CH, Wright J, Rubin JB, Berens ME, Lathia J, Connor JR, Kruchko C, Sloan AE, Barnholtz-Sloan JS.
Sex is an important prognostic factor for glioblastoma but not for nonglioblastoma.
Neurooncol Pract. 2019 Dec;6(6):451-462. doi: 10.1093/nop/npz019. Epub 2019 May 18.
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Lazaridis L, Schäfer N, Teuber-Hanselmann S, Blau T, Schmidt T, Oster C, Weller J, Tzaridis T, Pierscianek D, Keyvani K, Kleinschnitz C, Stuschke M, Scheffler B, Deuschl C, Sure U, Herrlinger U, Kebir S, Glas M.
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma.
J Cancer Res Clin Oncol. 2019 Dec 11. doi: 10.1007/s00432-019-03106-8. [Epub ahead of print]
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Li G, Zhai Y, Wang Z, Wang Z, Huang R, Jiang H, Li R, Feng Y, Chang Y, Jiang T, Zhang W.
Postoperative standard chemoradiotherapy benefits primary glioblastoma patients of all ages.
Cancer Med. 2019 Dec 18. doi: 10.1002/cam4.2754. [Epub ahead of print]
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Nie Q, Hsiao MC, Chandok H, Rowe S, Prego M, Meyers B, Omerza G, Hesse A, Uvalic J, Soucy M, Bergeron D, Peracchio M, Burns S, Kelly K, Rueter J, Reddi HV.
Molecular profiling of CNS tumors for the treatment and management of disease.
J Clin Neurosci. 2019 Dec 16. doi: 10.1016/j.jocn.2019.11.035. [Epub ahead of print]
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Pilati E, Nicolotti DG, Ceci F, Finessi M, Cerio I, Dionisi B, Zotta M, Bellò M, Deandreis D.
68Ga-Prostate-Specific Membrane Antigen 11 PET/CT Detects Residual Glioblastoma After Radical Surgery in a Patient With Synchronous Recurrent Prostate Cancer: A Case Report.
Clin Nucl Med. 2019 Dec 23. doi: 10.1097/RLU.0000000000002884. [Epub ahead of print]
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Vaitkiene P, Urbanaviciute R, Grigas P, Steponaitis G, Tamasauskas A, Skiriutė D.
Identification of Astrocytoma Blood Serum Protein Profile.
Cells. 2019 Dec 19;9(1). pii: E16. doi: 10.3390/cells9010016.
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Wang L, Babikir H, Müller S, et al.
The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation.
Cancer Discov. 2019;9(12):1708–1719. Published 2019 Sep 25. doi:10.1158/2159-8290.CD-19-0329.
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Wang Y, Meng X, Zhou S, Zhu Y, Xu J, Tao R.
Apatinib Plus Temozolomide for Recurrent Glioblastoma: An Uncontrolled, Open-Label Study.
Onco Targets Ther. 2019;12:10579–10585. Published 2019 Dec 3. doi:10.2147/OTT.S226804
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Zhou N, Wei ZX, Qi ZX.
Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells.
BMC Neurosci. 2019 Dec 23;20(1):63. doi: 10.1186/s12868-019-0545-1.
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GLIOSARCOMA



Huang Q, Li F, Chen Y, Hong F, Wang H, Chen J.
Prognostic factors and clinical outcomes in adult primary gliosarcoma patients: a Surveillance, Epidemiology, and End Results (SEER) analysis from 2004 to 2015.
Br J Neurosurg. 2019 Dec 12:1-7. doi: 10.1080/02688697.2019.1699903. [Epub ahead of print]
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EMBRYONAL TUMORS



MEDULLOBLASTOMA



Aiello G, Ballabio C, Ruggeri R, Fagnocchi L, Anderle M, Morassut I, Caron D, Garilli F, Gianno F, Giangaspero F, Piazza S, Romanel A, Zippo A, Tiberi L.
Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma.
Cell Rep. 2019 Dec 17;29(12):4036-4052.e10. doi: 10.1016/j.celrep.2019.11.046.
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Van Ommeren R, Garzia L, Holgado BL, Ramaswamy V, Taylor MD.
Mini-symposium: The molecular biology of medulloblastoma metastasis.
Brain Pathol. 2019 Dec 28. doi: 10.1111/bpa.12811. [Epub ahead of print]
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METASTATIC TUMORS


Ganau M, Gallinaro P, Cebula H, Scibilia A, Todeschi J, Gubian A, Nannavecchia B, Signorelli F, Pop R, Coca HA, Proust F, Chibbaro S.
Intracranial Metastases from Prostate Carcinoma: Classification, Management, and Prognostication.
World Neurosurg. 2019 Oct 31. doi: 10.1016/j.wneu.2019.10.125. [Epub ahead of print]
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