Current Neuro-Oncology




Volume 22 Number 8
30 April 2020




Home > Publications > Current Neuro-Oncology > Volume 22, Year 2020 > Number 8, 30 April






Maas SLN, Abels ER, Van De Haar LL, Zhang X, Morsett L, Sil S, Guedes J, Sen P, Prabhakar S, Hickman SE, Lai CP, Ting DT, Breakefield XO, Broekman MLD, El Khoury J.
Glioblastoma hijacks microglial gene expression to support tumor growth.
J Neuroinflammation. 2020 Apr 16, 2020;17(1):120
. doi: 10.1186/s12974-020-01797-2. PMID: 32299465. Laboratory investigation. ˍ




Moser O, Zimmermann M, Meyer U, Klapper W, Oschlies I, Schrappe M, Attarbaschi A, Mann G, Niggli F, Spix C, Kontny U, Klingebiel T, Reiter A, Burkhardt B, Woessmann W.
Second malignancies after treatment of childhood non-Hodgkin lymphoma: a report of the Berlin-Frankfurt-Muenster study group.
Haematologica. 2020 Apr 16, 2021;106(5):1390-1400
. doi: 10.3324/haematol.2019.244780. PMID: 32299903. Observational study. ˍ




Regueira PSS, Cerejeira JMS.
Delirium as the primary manifestation of glioblastoma multiforme: a report of two cases.
Psychogeriatrics. 2020 Apr 16, 2020 Sep;20(5):782-784
. doi: 10.1111/psyg.12555. PMID: 32297428. Case report. ˍ




Weathers SP, Penas-Prado M, Pei BL, Ling X, Kassab C, Banerjee P, Bdiwi M, Shaim H, Alsuliman A, Shanley M, de Groot JF, O'Brien BJ, Harrison R, Majd N, Kamiya-Matsuoka C, Fuller GN, Huse JT, Chi L, Rao G, Weinberg JS, Lang FF, Sawaya R, Shpall EJ, Rezvani K, Heimberger AB.
Glioblastoma-mediated immune dysfunction limits CMV-specific T cells and therapeutic responses; results from a Phase I/II trial.
Clin Cancer Res. 2020 Apr 16, 2020;26(14):3565-3577
. doi: 10.1158/1078-0432.CCR-20-0176. PMID: 32299815. Interventional study. ˍ




Bellat V, Alcaina Y, Tung CH, Ting R, Michel A, Souweidane M, Law B.
A Combined Approach of Convection-Enhanced Delivery of Peptide Nanofiber Reservoir to Prolong Delivery of DM1 for Diffuse Intrinsic Pontine Glioma Treatment.
Neuro Oncol. 2020 Apr 17, 2020;22(10):1495-1504
. doi: 10.1093/neuonc/noaa101. PMID: 32301996. Laboratory investigation. ˍ




Bette S, Barz M, Ly Nham H, Huber T, Berndt M, Sales A, Schmidt-Graf F, Meyer HS, Ryang YM, Meyer B, Zimmer C, Kirschke JS, Wiestler B, Gempt J.
Image Analysis Reveals Microstructural and Volumetric Differences in Glioblastoma Patients with and without Preoperative Seizures.
Cancers
(Basel). 2020 Apr 17, 2020;12(4):E994. doi: 10.3390/cancers12040994. PMID: 32316566. Observational study. ˍ




Zigiotto L, Annicchiarico L, Corsini F, Vitali L, Falchi R, Dalpiaz C, Rozzanigo U, Barbareschi M, Avesani P, Papagno C, Duffau H, Chioffi F, Sarubbo S.
Effects of supra-total resection in neurocognitive and oncological outcome of high-grade gliomas comparing asleep and awake surgery.
J Neurooncol. 2020 Apr 17, 2020;148(1):97-108
. doi: 10.1007/s11060-020-03494-9. PMID: 32303975. Observational study. ˍ




Dhall G, O'Neil SH, Ji L, Haley K, Whitaker AM, Nelson MD, Gilles F, Gardner SL, Allen JC, Cornelius AS, Pradhan K, Garvin JH, Olshefski RS, Hukin J, Comito M, Goldman S, Atlas MP, Walter AW, Sands S, Sposto R, Finlay JL.
Excellent Outcome of Young Children with Nodular Desmoplastic Medulloblastoma Treated on "Head Start" III: A Multi-Institutional, Prospective Clinical Trial.
Neuro Oncol.
2020 Apr 18, 2020;22(12):1862-1872. doi: 10.1093/neuonc/noaa102. PMID: 32304218. Interventional study. ˍ




Guberina N, Pöttgen C, Kebir S, Lazaridis L, Scharmberg C, Lübcke W, Niessen M, Guberina M, Scheffler B, Jendrossek V, Jabbarli R, Pierscianek D, Sure U, Schmidt T, Oster C, Hau P, Grosu AL, Stuschke M, Glas M, Nour Y, Lüdemann L.
Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial.
Radiat Oncol. 2020 Apr 19, 2020;15(1):83
. doi: 10.1186/s13014-020-01521-7. PMID: 32307022. Interventional study. ˍ




Assi HI, Hilal L, Abu-Gheida I, Berro J, Sukhon F, Skaf G, Geara F, Boulos F, Charafeddine M, Tabbarah A, Khoury J, Najjar M.
Demographics and outcomes of meningioma patients treated at a tertiary care center in the Middle East.
Clin Neurol Neurosurg.
2020 Apr 20, 2020;195:105846. doi: 10.1016/j.clineuro.2020.105846. PMID: 32334046. Observational study. ˍ



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Carminucci A, Tejero R, Huang Y, Danish S, Friedel RH, Foty R.
Teaching an Old Drug New Tricks: Dexamethasone as an In Vivo Inhibitor of Glioblastoma Dispersal.
Cureus. 2020 Apr 20, 2020;12(4):e7749
. doi: 10.7759/cureus.7749. PMID: 32455066. Laboratory investigation. ˍ




Bokstein F, Blumenthal D, Limon D, Harosh CB, Ram Z, Grossman R.
Concurrent Tumor Treating Fields (TTFields) and Radiation Therapy for Newly Diagnosed Glioblastoma: A Prospective Safety and Feasibility Study.
Front Oncol. 2020 Apr 21, 2020;10:411. doi: 10.3389/fonc.2020.00411. PMID: 32373508. Interventional study. ˍ




Maiuri F, Mariniello G, Peca C, Guadagno E, Corvino S, d'Avanzo S, Del Basso De Caro M, de Divitiis O.
Multicentric and diffuse recurrences of meningiomas.
Br J Neurosurg. 2020 Apr 21, 2020;34(4):439-446. doi: 10.1080/02688697.2020.1754335. PMID: 32312105. Observational study. ˍ




Maynard J, Okuchi S, Wastling S, Busaidi AA, Almossawi O, Mbatha W, Brandner S, Jaunmuktane Z, Koc AM, Mancini L, Jäger R, Thust S.
World Health Organization Grade II/III Glioma Molecular Status: Prediction by MRI Morphologic Features and Apparent Diffusion Coefficient.
Radiology. 2020 Apr 21, 2020;296(1):111-121. doi: 10.1148/radiol.2020191832. PMID: 32315266. Observational study. ˍ




Stein M, Dohmen H, Wölk B, Eberle F, Kolodziej M, Acker T, Uhl E, Jensen A.
Case Report of Complete Radiological Response of a Thalamic Glioblastoma After Treatment With Proton Therapy Followed by Temozolomide and Tumor-Treating Fields.
Front Oncol. 2020 Apr 21, 2020;10:477. doi: 10.3389/fonc.2020.00477. PMID: 32373516. Case report. ˍ




Troya-Castilla M, Kaen A, Márquez-Rivas FJ, Cossio PI, Díaz FR, Narros Gimenez JL, Gonzalez-Pombo M, Cancela P, Fernández-Nogueras MS, Arráez MÁ.
Impact of early re-operation on the prognosis of patients operated on for glioblastoma.
World Neurosurg. 2020 Apr 21, 2020;139:e592-e600. doi: 10.1016/j.wneu.2020.04.072. PMID: 32330620. Observational study. ˍ




Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM.
Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas.
Neuro Oncol. 2020 Apr 22, 2020;22(10):1516-1526. doi: 10.1093/neuonc/noaa094. PMID: 32319527. Observational study. ˍ




Saeed AM, Khairnar R, Sharma AM, Larson GL, Tsai HK, Wang CJ, Halasz LM, Chinnaiyan P, Vargas CE, Mishra MV.
Clinical Outcomes in Patients with Recurrent Glioblastoma Treated with Proton Beam Therapy Reirradiation: Analysis of the Multi-Institutional Proton Collaborative Group Registry.
Adv Radiat Oncol. 2020 Apr 22, 2020;5(5):978-983
. doi: 10.1016/j.adro.2020.03.022. PMID: 33083661. Observational study. ˍ




Chiang J, Diaz AK, Makepeace L, Li X, Han Y, Li Y, Klimo P Jr, Boop FA, Baker SJ, Gajjar A, Merchant TE, Ellison DW, Broniscer A, Patay Z, Tinkle CL.
Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG.
Acta Neuropathol Commun. 2020 Apr 23, 2020;8(1):57. doi: 10.1186/s40478-020-00930-9. PMID: 32326973. Observational study. ˍ




Darvishi P, Batchala PP, Patrie JT, Poisson LM, Lopes MB, Jain R, Fadul CE, Schiff D, Patel SH.
Prognostic Value of Preoperative MRI Metrics for Diffuse Lower-Grade Glioma Molecular Subtypes.
AJNR Am J Neuroradiol. 2020 Apr 23, 2020;41(5):815-821. doi: 10.3174/ajnr.A6511. PMID: 32327434. Observational study. ˍ




Feraco P, Bacci A, Ferrazza P, van den Hauwe L, Pertile R, Girlando S, Barbareschi M, Gagliardo C, Morganti AG, Petralia B.
Magnetic Resonance Imaging Derived Biomarkers of IDH Mutation Status and Overall Survival in Grade III Astrocytomas.
Diagnostics
(Basel). 2020 Apr 23, 2020;10(4):E247. doi: 10.3390/diagnostics10040247. PMID: 32340318. Observational study. ˍ




Hong JB, Roh TH, Kang SG, Kim SH, Moon JH, Kim EH, Ahn SS, Choi HJ, Cho J, Suh CO, Chang JH.
Survival, Prognostic Factors, and Volumetric Analysis of Extent of Resection for Anaplastic Gliomas.
Cancer Res Treat. 2020 Apr 23, 2020;52(4):1041-1049. doi: 10.4143/crt.2020.057. PMID: 32324987. Observational study. ˍ




Wang X, Li F, Wang D, Zeng Q.
Diffusion kurtosis imaging combined with molecular markers as a comprehensive approach to predict overall survival in patients with gliomas.
Eur J Radiol. 2020 Apr 23, 2020;128:108985. doi: 10.1016/j.ejrad.2020.108985. PMID: 32361603. Observational study. ˍ




Balana C, Vaz MA, Sepúlveda JM, Mesia C, Del Barco S, Pineda E, Muñoz-Langa J, Estival A, de Las Peñas R, Fuster J, Gironés R, Navarro LM, Gil-Gil M, Alonso M, Herrero A, Peralta S, Olier C, Perez-Segura P, Covela M, Martinez-García M, Berrocal A, Gallego O, Luque R, Perez-Martín FJ, Esteve A, Munne N, Domenech M, Villa S, Sanz C, Carrato C.
A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond six cycles in patients with glioblastoma (GEINO 14-01).
Neuro Oncol. 2020 Apr 24, 2020;22(12):1851-1861. doi: 10.1093/neuonc/noaa107. PMID: 32328662. Interventional study. ˍ




Bergmann N, Delbridge C, Gempt J, Feuchtinger A, Walch A, Schirmer L, Bunk W, Aschenbrenner T, Liesche-Starnecker F, Schlegel J.
The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis.
Front Oncol. 2020 Apr 24, 2020;10:494. doi: 10.3389/fonc.2020.00494. PMID: 32391260. Laboratory investigation. ˍ




Loong HH, Wong AM, Chan DT, Cheung MS, Chow C, Ding X, Chan AK, Johnston PA, Lau JY, Poon WS, Wong N.
Patient-derived tumor organoid predicts drugs response in glioblastoma: A step forward in personalized cancer therapy?
J Clin Neurosci. 2020 Apr 24, 2020;78:400-402. doi: 10.1016/j.jocn.2020.04.107. PMID: 32340843. Case report. ˍ




Mynarek M, von Hoff K, Pietsch T, Ottensmeier H, Warmuth-Metz M, Bison B, Pfister S, Korshunov A, Sharma T, Jaeger N, Ryzhova M, Zheludkova O, Golanov A, Rushing EJ, Hasselblatt M, Koch A, Schüller U, von Deimling A, Sahm F, Sill M, Riemenschneider MJ, Dohmen H, Monoranu CM, Sommer C, Staszewski O, Mawrin C, Schittenhelm J, Brück W, Filipski K, Hartmann C, Meinhardt M, Pietschmann K, Haberler C, Slavc I, Gerber NU, Grotzer M, Benesch M, Schlegel PG, Deinlein F, von Bueren AO, Friedrich C, Juhnke BO, Obrecht D, Fleischhack G, Kwiecien R, Faldum A, Kortmann RD, Kool M, Rutkowski S.
Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.
J Clin Oncol. 2020 Apr 24, 2020;38(18):2028-2040. doi: 10.1200/JCO.19.03057. PMID: 32330099. Interventional study. ˍ




Capo G, Skrap M, Guarracino I, Isola M, Battistella C, Ius T, Tomasino B.
Cognitive Functions in Repeated Glioma Surgery.
Cancers (Basel). 2020 Apr 26, 2020;12(5):E1077. doi: 10.3390/cancers12051077. PMID: 32357421. Observational study. ˍ




Brazil L, Swampillai AL, Mak KM, Edwards D, Mesiri P, Clifton-Hadley L, Shaffer R, Lewis J, Watts C, Jeffries S, Gkogkou P, Chalmers AJ, Fersht NL, Hackshaw A, Short SC.
Hydroxychloroquine and short-course radiotherapy in elderly patients with newly diagnosed high-grade glioma: a randomized phase II trial.
Neurooncol Adv. 2020 Apr 27, 2020;2(1):vdaa046. doi: 10.1093/noajnl/vdaa046. PMID: 32642699. Interventional study. ˍ




Donovan LK, Delaidelli A, Joseph SK, Bielamowicz K, Fousek K, Holgado BL, Manno A, Srikanthan D, Gad AZ, Van Ommeren R, Przelicki D, Richman C, Ramaswamy V, Daniels C, Pallota JG, Douglas T, Joynt ACM, Haapasalo J, Nor C, Vladoi:u MC, Kuzan-Fischer CM, Garzia L, Mack SC, Varadharajan S, Baker ML, Hendrikse L, Ly M, Kharas K, Balin P, Wu X, Qin L, Huang N, Stucklin AG, Morrissy AS, Cavalli FMG, Luu B, Suarez R, De Antonellis P, Michealraj A, Rastan A, Hegde M, Komosa M, Sirbu O, Kumar SA, Abdullaev Z, Faria CC, Yip S, Hukin J, Tabori U, Hawkins C, Aldape K, Daugaard M, Maris JM, Sorensen PH, Ahmed N, Taylor MD.
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.
Nat Med. 2020 Apr 27;26(5):720‐731. doi: 10.1038/s41591-020-0827-2. PMID: 32341580. Laboratory investigation. ˍ




Mair MJ, Wöhrer A, Furtner J, Simonovska A, Kiesel B, Oberndorfer S, Ungersböck K, Marosi C, Sahm F, Hainfellner JA, Rössler K, Preusser M, Widhalm G, Berghoff AS.
Clinical characteristics and prognostic factors of adult patients with pilocytic astrocytoma.
J Neurooncol.
2020 Apr 27, 2020;148(1):187-198. doi: 10.1007/s11060-020-03513-9. PMID: 32342331. Observational study. ˍ




Tabrizi S, Trippa L, Cagney D, Tanguturi S, Ventz S, Fell G, Wen PY, Alexander BM, Rahman R.
A Quantitative Framework for Modeling COVID-19 Risk During Adjuvant Therapy Using Pub Randomized Trials of Glioblastoma in the Elderly.
Neuro Oncol. 2020 Apr 27, 2020;22(7):918-927. doi: 10.1093/neuonc/noaa111. PMID: 32339235. Observational study. ˍ




Press RH, Shafer SL, Jiang R, Buchwald ZS, Abugideiri M, Tian S, Morgan TM, Behera M, Sengupta S, Voloschin AD, Olson JJ, Hasan S, Blumenthal DT, Curran WJ, Eaton BR, Shu HG, Zhong J.
Optimal timing of chemoradiotherapy after surgical resection of glioblastoma: Stratification by validated prognostic classification.
Cancer. 2020 Apr 28, 2020;126(14):3255-3264. doi: 10.1002/cncr.32797. PMID: 32342992. Observational study. ˍ




Ramakrishnan V, Xu B, Akers J, Nguyen T, Ma J, Dhawan S, Ning J, Mao Y, Hua W, Kokkoli E, Furnari F, Carter BS, Chen CC.
Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas.
EBioMedicine. 2020 Apr 28, 2020;55:102736. doi: 10.1016/j.ebiom.2020.102736. PMID: 32361246. Laboratory investigation. ˍ




Suradom C, Suttajit S, Soontornpun A, Pinyopornpanish M.
Frontal lobe meningioma presenting with schizophrenia-like symptoms: an organic cause of psychotic disorder.
BMJ Case Rep. 2020 Apr 28, 2020;13(4):e234526. doi: 10.1136/bcr-2020-234526. PMID: 32350055. Case report. ˍ




Zhao K, Sun G, Wang Q, Xue Z, Liu G, Xia Y, Yao A, Zhao Y, You N, Yang C, Xu B.
The Diagnostic Value of Conventional MRI and CT Features in the Identification of the IDH1-Mutant and 1p/19q Co-Deletion in WHO Grade II Gliomas.
Acad Radiol. 2020 Apr 28, 2020;28(7):e189-e198. doi: 10.1016/j.acra.2020.03.008. PMID: 32359929. Observational study. ˍ




Alan O, Telli TA, Tuylu TB, Arikan R, Demircan NC, Ercelep O, Kaya S, Babacan NA, Atasoy BM, Bozkurt S, Bayri Y, Gul D, Ekinci G, Ziyal I, Dane F, Yumuk PF.
Prognostic factors in progressive high-grade glial tumors treated with systemic approach: A single center experience.
J Oncol Pharm Pract. 2020 Apr 29, 2021;27(2):329-339. doi: 10.1177/1078155220920684. PMID: 32349641. Observational study. ˍ




Brown DA, Hanalioglu S, Chaichana K, Duffau H.
Transcorticosubcortical Approach for Left Posterior Mediobasal Temporal Region Gliomas: A Case Series and Anatomic Review of Relevant White Matter Tracts.
World Neurosurg. 2020 Apr 29, 2020;139:e737-e747. doi: 10.1016/j.wneu.2020.04.147. PMID: 32360919. Case report. ˍ




Fang S, Li Y, Wang Y, Zhang Z, Jiang T.
Awake craniotomy for gliomas involving motor-related areas: classification and function recovery.
J Neurooncol. 2020 Apr 29, 2020;148(2):317-325. doi: 10.1007/s11060-020-03520-w. PMID: 32350781. Observational study. ˍ




Visani M, Marucci G, Biase D, Giangaspero F, Buttarelli FR, Brandes AA, Franceschi E, Acquaviva G, Ciarrocchi A, Rhoden KJ, Tallini G, Pession A.
miR-196B-5P and miR-200B-3P Are Differentially Expressed in Medulloblastomas of Adults and Children.
Diagnostics (Basel). 2020 Apr 29, 2020;10(5):E265. doi: 10.3390/diagnostics10050265. PMID: 32365560. Laboratory investigation. ˍ




Choi MG, Lee JH, Lee MS, Suh SJ, Lee YS, Kang DG.
Primary Gliosarcoma with Extracranial Metastasis.
Brain Tumor Res Treat. 2020 Apr 30, 2020;8(1):53-56. doi: 10.14791/btrt.2020.8.e9. PMID: 32390354. Case report. ˍ




Choi Y, Nam Y, Lee YS, Kim J, Ahn KJ, Jang J, Shin NY, Kim BS, Jeon SS.
IDH1 mutation prediction using MR-based radiomics in glioblastoma: comparison between manual and fully automated deep learning-based approach of tumor segmentation.
Eur J Radiol. 2020 Apr 30, 2020;128:109031. doi: 10.1016/j.ejrad.2020.109031. PMID: 32417712. Observational study. ˍ




Kian W, Roisman LC, Goldstein IM, Abo-Quider A, Samueli B, Wallach N, Alguayn F, Shalata W, Levitas D, Belochitski O, Levin D, Fenig E, Lavrenkov K, Tokar M, Peled N, Yakobson A.
Vismodegib as First-Line Treatment of Mutated Sonic Hedgehog Pathway in Adult Medulloblastoma.
JCO Precis Oncol. 2020 Apr 30,
2020;4:PO.19.00264. doi: 10.1200/PO.19.00264. PMID: 32923880. Case report. ˍ




Kim MS, Lim J, Shin HS, Cho KG.
Re-Irradiation and Its Contribution to Good Prognosis in Recurrent Glioblastoma Patients.
Brain Tumor Res Treat. 2020 Apr 30, 2020;8(1):29-35. doi: 10.14791/btrt.2020.8.e10. PMID: 32390351. Observational study. ˍ




Robinson GW, Gajjar A.
Genomics Paves the Way for Better Infant Medulloblastoma Therapy.
J Clin Oncol. 2020 Apr 30, 2020;38(18):2010-2013. doi: 10.1200/JCO.20.00593. PMID: 32352857. Editorial. ˍ
Refers to: Mynarek M, et al., Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.
J Clin Oncol. 2020 Apr 24, 2020;38(18):2028-2040
. doi: 10.1200/JCO.19.03057. PMID: 32330099. Interventional study. ˍ




Sidaway P.
Low-grade glioma subtypes revealed.
Nat Rev Clin Oncol. 2020 April 30;17(6):335. doi: 10.1038/s41571-020-0380-4. PMID: 32355316. Comment. ˍ
REFERS TO: Ryall S, et al., Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas.
Cancer Cell. 2020 Apr 13;37(4):569‐583.e5
. doi: 10.1016/j.ccell.2020.03.011. PMID: 32289278. Laboratory investigation, Observational study. ˍ