Current Neuro-Oncology

Volume 22 Number 20
31 October 2020

Home > Publications > Current Neuro-Oncology > Volume 22, Year 2020 > Number 20, 31 October

Awada G, Ben Salama L, De Cremer J, Schwarze JK, Fischbuch L, Seynaeve L, Du Four S, Vanbinst AM, Michotte A, Everaert H, Rogiers A, Theuns P, Duerinck J, Neyns B.
Axitinib plus avelumab in the treatment of recurrent glioblastoma: a stratified, open-label, single-center phase 2 clinical trial (GliAvAx).
J Immunother Cancer. 2020 Oct 16, 2020;8(2):e001146
. doi: 10.1136/jitc-2020-001146. PMID: 33067319. Interventional study. ˍ

Li G, Wu F, Zeng F, Zhai Y, Feng Y, Chang Y, Wang D, Jiang T, Zhang W.
A novel DNA repair-related nomogram predicts survival in low-grade gliomas.
CNS Neurosci Ther. 2020 Oct 16, 2021;27(2):186-195
. doi: 10.1111/cns.13464. PMID: 33063446. Observational study. ˍ

Kondo N, Hikida M, Nakada M, Sakurai Y, Hirata E, Takeno S, Suzuki M.
Glioma Stem-Like Cells Can Be Targeted in Boron Neutron Capture Therapy with Boronophenylalanine.
(Basel). 2020 Oct 19, 2020;12(10):3040. doi: 10.3390/cancers12103040. PMID: 33086625. Laboratory investigation. ˍ

Seaman SC, Bathla G, Park BJ, Woodroffe RW, Smith M, Menezes AH, Noeller J, Yamaguchi S, Hitchon PW.
MRI characteristics and resectability in spinal cord glioma.
Clin Neurol Neurosurg. 2020 Oct 19, 2021;200:106321
. doi: 10.1016/j.clineuro.2020.106321. PMID: 33268194. Observational study. ˍ

Brigliadori G, Goffredo G, Bartolini D, Tosatto L, Gurrieri L, Mercatali L, Ibrahim T.
Influence of Intratumor Heterogeneity on the Predictivity of MGMT Gene Promoter Methylation Status in Glioblastoma.
Front Oncol. 2020 Oct 20, 2020;10:533000
. doi: 10.3389/fonc.2020.533000. PMID: 33194592. Observational study. ˍ

Irfan N, Samuel E, Rafi Ranjha F, Waheed A, Abu Bakar M, Usman S, Butt S, Rashid A, Yousaf I.
Toxicity Profile of Procarbazine Lomustine and Vincristine Chemotherapy in Low-Grade Glioma - Retrospective Review.
Cureus. 2020 Oct 20, 2020;12(10):e11070
. doi: 10.7759/cureus.11070. PMID: 33224664. Observational study. ˍ


Hu C, Lin Q, Liu C, Liu J, Chen X, Li X, Zhao G, Zhang L.
Bioequivalence study of 20-mg and 100-mg temozolomide capsules (TOZ309 and Temodal®) in glioma patients in China.
Cancer Chemother Pharmacol. 2020 Oct 21, 2020;86(6):793-801
. doi: 10.1007/s00280-020-04175-0. PMID: 33089408. Interventional study. ˍ

Khalafallah AM, Jimenez AE, Shah PP, Brem H, Mukherjee D.
Effect of radiation therapy on overall survival following subtotal resection of adult pilocytic astrocytoma.
J Clin Neurosci. 2020 Oct 21. 2020;81:340-345
. doi: 10.1016/j.jocn.2020.10.020. PMID: 33222942. Observational study. ˍ

Makarevic A, Rapp C, Dettling S, Reuss D, Jungk C, Abdollahi A, von Deimling A, Unterberg A, Herold-Mende C, Warta R.
Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma.
Int J Mol Sci. 2020 Oct 21, 2020;21(20):7801
. doi: 10.3390/ijms21207801. PMID: 33096928. Laboratory investigation. ˍ

Wu W, Deng Z, Alafate W, Wang Y, Xiang J, Zhu L, Li B, Wang M, Wang J.
Preoperative Prediction Nomogram Based on Integrated Profiling for Glioblastoma Multiforme in Glioma Patients.
Front Oncol. 2020 Oct 21, 2020;10:1750
. doi: 10.3389/fonc.2020.01750. PMID: 33194573. Observational study. ˍ

Yan J, Zhang S, Li KK, Wang W, Li K, Duan W, Yuan B, Wang L, Liu L, Zhan Y, Pei D, Zhao H, Sun T, Sun C, Wang W, Liu Z, Hong X, Wang X, Guo Y, Li W, Cheng J, Liu X, Ng HK, Li Z, Zhang Z.
Incremental prognostic value and underlying biological pathways of radiomics patterns in medulloblastoma.
EBioMedicine. 2020 Oct 21, 2020;61:103093
. doi: 10.1016/j.ebiom.2020.103093. PMID: 33096488. Observational study. ˍ

Butenschoen VM, Hubertus V, Janssen IK, Onken J, Wipplinger C, Mende KC, Eicker SO, Kehl V, Thomé C, Vajkoczy P, Schaller K, Gempt J, Meyer B, Wostrack M.
Surgical treatment and neurological outcome of infiltrating intramedullary astrocytoma WHO II-IV: a multicenter retrospective case series.
J Neurooncol. 2020 Oct 22, 2021;151(2):181-191
. doi: 10.1007/s11060-020-03647-w. PMID: 33094355. Observational study. ˍ

Dastghaib S, Shojaei S, Mostafavi-Pour Z, Sharma P, Patterson JB, Samali A, Mokarram P, Ghavami S.
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
Cells. 2020 Oct 22, 2020;9(11):E2339
. doi: 10.3390/cells9112339. PMID: 33105603. Laboratory investigation. ˍ

Dorfer C, Czech T, Gojo J, Hosmann A, Peyrl A, Azizi AA, Kasprian G, Dieckmann K, Filbin MG, Haberler C, Roessler K, Slavc I.
Infiltrative gliomas of the thalamus in children: the role of surgery in the era of H3 K27M mutant midline gliomas.
Acta Neurochir
(Wien). 2020 Oct 22, 2021;163(7):2025-2035. doi: 10.1007/s00701-020-04589-y. PMID: 33090244. Observational study. ˍ

Hill RM, Richardson S, Schwalbe EC, Hicks D, Lindsey JC, Crosier S, Rafiee G, Grabovska Y, Wharton SB, Jacques TS, Michalski A, Joshi A, Pizer B, Williamson D, Bailey S, Clifford SC.
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study.
Lancet Child Adolesc Health. 2020 Oct 22, 2020;4(12):865-874
. doi: 10.1016/S2352-4642(20)30246-7. PMID: 33222802. Observational study. ˍ

Kong Z, Jiang C, Zhang Y, Liu S, Liu D, Liu Z, Chen W, Liu P, Yang T, Lyu Y, Zhao D, You H, Wang Y, Ma W, Feng F.
Thin-Slice Magnetic Resonance Imaging-Based Radiomics Signature Predicts Chromosomal 1p/19q Co-deletion Status in Grade II and III Gliomas.
Front Neurol. 2020 Oct 22, 2020;11:551771
. doi: 10.3389/fneur.2020.551771. PMID: 33192984. Observational study. ˍ

Franco P, Delev D, Cipriani D, Neidert N, Kellner E, Masalha W, Mercas B, Mader I, Reinacher P, Weyerbrock A, Fung C, Beck J, Heiland DH, Schnell O.
Surgery for IDH1/2 wild-type glioma invading the corpus callosum.
Acta Neurochir
(Wien). 2020 Oct 23, 2021;163(4):937-945. doi: 10.1007/s00701-020-04623-z. PMID: 33095353. Observational study. ˍ

Niu L, Feng WH, Duan CF, Liu YC, Liu JH, Liu XJ.
The Value of Enhanced MR Radiomics in Estimating the IDH1 Genotype in High-Grade Gliomas.
Biomed Res Int. 2020 Oct 24, 2020;2020:4630218
. doi: 10.1155/2020/4630218. PMID: 33163535. Observational study. ˍ

Pan ZQ, Zhang SJ, Wang XL, Jiao YX, Qiu JJ.
Machine Learning Based on a Multiparametric and Multiregional Radiomics Signature Predicts Radiotherapeutic Response in Patients with Glioblastoma.
Behav Neurol. 2020 Oct 24, 2020;2020:1712604
. doi: 10.1155/2020/1712604. PMID: 33163122. Observational study. ˍ

Morana G, Tortora D, Bottoni G, Puntoni M, Piatelli G, Garibotto F, Barra S, Giannelli F, Cistaro A, Severino M, Verrico A, Milanaccio C, Massimino M, Garrè ML, Rossi A, Piccardo A.
Correlation of multimodal 18F-DOPA PET and conventional MRI with treatment response and survival in children with diffuse intrinsic pontine gliomas.
Theranostics. 2020 Oct 25, 2020;10(26):11881-11891
. doi: 10.7150/thno.50598. PMID: 33204317. Observational study. ˍ


Öksüz E, Görgİşen G, Özdemİr H, Gülaçar İM, Oto G.
Effect of paracetamol in the proliferation of glioblastoma cell line: The role of apoptosis, COX-2 and cyclin B expressions.
Turk Neurosurg. 2020 Oct 26, 2021;31(1):46-50
. doi: 10.5137/1019-5149.JTN.27866-19.7. PMID: 33216331. Laboratory investigation. ˍ

Prabhu RS, Ward MC, Heinzerling JH, Corso CD, Buchwald ZS, Dhakal R, Asher AL, Sumrall AL, Burri SH.
The Association Between Radiation Therapy Dose and Overall Survival in Patients With Intracranial Infiltrative Low-Grade Glioma Treated With Concurrent and/or Adjuvant Chemotherapy.
Adv Radiat Oncol. 2020 Oct 26, 2021;6(1):100577
. doi: 10.1016/j.adro.2020.09.017. PMID: 33665485. Observational study. ˍ

Escudero L, Llort A, Arias A, Diaz-Navarro A, Martínez-Ricarte F, Rubio-Perez C, Mayor R, Caratù G, Martínez-Sáez E, Vázquez-Méndez É, Lesende-Rodríguez I, Hladun R, Gros L, Ramón Y Cajal S, Poca MA, Puente XS, Sahuquillo J, Gallego S, Seoane J.
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma.
Nat Commun. 2020 Oct 27, 2020;11(1):5376
. doi: 10.1038/s41467-020-19175-0. PMID: 33110059. Laboratory investigation. ˍ

Sakai Y, Yang C, Kihira S, Tsankova N, Khan F, Hormigo A, Lai A, Cloughesy T, Nael K.
MRI Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A Machine Learning Approach using Gradient Tree Boosting.
Int J Mol Sci. 2020 Oct 27, 2020;21(21):E8004
. doi: 10.3390/ijms21218004. PMID: 33121211. Observational study. ˍ

Xue C, Zhang B, Deng J, Liu X, Li S, Zhou J.
Differentiating Giant Cell Glioblastoma from Classic Glioblastoma With Diffusion-Weighted Imaging.
World Neurosurg. 2020 Oct 27, 2021;146:e473-e478
. doi: 10.1016/j.wneu.2020.10.125. PMID: 33127573. Observational study. ˍ


Cataldi S, Arcuri C, Lazzarini A, Nakashidze I, Ragonese F, Fioretti B, Ferri I, Conte C, Codini M, Beccari T, Curcio F, Albi E.
Effect of 1α,25(OH)2 Vitamin D3 in Mutant P53 Glioblastoma Cells: Involvement of Neutral Sphingomyelinase1.
(Basel). 2020 Oct 28, 2020;12(11):3163. doi: 10.3390/cancers12113163. PMID: 33126474. Laboratory investigation. ˍ

Tzaridis T, Schäfer N, Weller J, Steinbach JP, Schlegel U, Seidel S, Sabel M, Hau P, Seidel C, Krex D, Goldbrunner R, Tonn JC, Grauer O, Kebir S, Schneider M, Schaub C, Vatter H, Coch C, Glas M, Fimmers R, Pietsch T, Reifenberger G, Herrlinger U, Felsberg J.
MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
Int J Cancer. 2020 Oct 28, 2021;148(7):1695-1707
. doi: 10.1002/ijc.33363. PMID: 33113214. Interventional study. ˍ

Climans SA, Macdonald DR, Sutherland DE, Mason WP.
Prolonged response to vismodegib in a patient with systemic medulloblastoma metastases.
BMJ Case Rep. 2020 Oct 29, 2020;13(10):e236406
. doi: 10.1136/bcr-2020-236406. PMID: 33122230. Case report. ˍ

Cloughesy TF, Petrecca K, Walbert T, Butowski N, Salacz M, Perry J, Damek D, Bota D, Bettegowda C, Zhu JJ, Iwamoto F, Placantonakis D, Kim L, Elder B, Kaptain G, Cachia D, Moshel Y, Brem S, Piccioni D, Landolfi J, Chen CC, Gruber H, Rao AR, Hogan D, Accomando W, Ostertag D, Montellano TT, Kheoh T, Kabbinavar F, Vogelbaum MA.
Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial.
JAMA Oncol. 2020 Oct 29,
2020;6(12):1939-1946. doi: 10.1001/jamaoncol.2020.3161. PMID: 33119048. Interventional study. ˍ

Coomans MB, Dirven L, Aaronson NK, Baumert BG, van den Bent M, Bottomley A, Brandes AA, Chinot O, Coens C, Gorlia T, Herrlinger U, Keime-Guibert F, Malmström A, Martinelli F, Sloan JA, Stupp R, Talacchi A, Weller M, Wick W, Reijneveld JC, Taphoorn MJB.
Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling.
Neurooncol Adv. 2020 Oct 29, 2020;2(1):vdaa147
. doi: 10.1093/noajnl/vdaa147. PMID: 33409496. Observational study. ˍ

Diao S, Gu C, Zhang H, Yu C.
Immune cell infiltration and cytokine secretion analysis reveal a non-inflammatory microenvironment of medulloblastoma.
Oncol Lett. 2020 Oct 29, 2020;20(6):397
. doi: 10.3892/ol.2020.12260. PMID: 33193857. Laboratory investigation. ˍ

Hsu PYH, Folkman F, Ghosh S, de Robles P, Leckie C, Dersch-Mills D, Coppens R, Chambers C.
Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma.
J Oncol Pharm Pract. 2020 Oct 29, 2021;27(7):1723-1729
. doi: 10.1177/1078155220968613. PMID: 33121351. Observational study. ˍ

Chia BSH, Leong JY, Ong ALK, Lim C, Poon SH, Chua MLK, Chua KLM, Kusumawidjaja G, Chua ET, Wong FY, Lee TS.
Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol.
BMC Cancer. 2020 Oct 30, 2020;20(1):1045
. doi: 10.1186/s12885-020-07565-y. PMID: 33126867. Protocol. ˍ

Ding XC, Wang LL, Zhu YF, Li YD, Nie SL, Yang J, Liang H, Weichselbaum RR, Yu JM, Hu M.
The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes.
Front Immunol. 2020 Oct 30, 2020;11:580335
. doi: 10.3389/fimmu.2020.580335. PMID: 33224142. Observational study. ˍ

Ostrom QT, Patil N, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2013-2017.
Neuro Oncol. 2020 Oct 30, 2020;
22(Suppl 1):iv1–iv96.ˍ. doi: 10.1093/neuonc/noaa200. PMID: 33123732. Observational study. ˍ

Ferguson SD, Hodges TR, Majd NK, Alfaro-Munoz K, Al-Holou WN, Suki D, de Groot JF, Fuller GN, Xue L, Li M, Jacobs C, Rao G, Colen RR, Xiu J, Verhaak R, Spetzler D, Khasraw M, Sawaya R, Long JP, Heimberger AB.
A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram.
Neurooncol Adv. 2020 Oct 31, 2021;3(1):vdaa146
. doi: 10.1093/noajnl/vdaa146. PMID: 33426529. Observational study. ˍ