Current
Neuro-Oncology


Volume 23 Number 18
September 2021


Home > Publications > Current Neuro-Oncology > Volume 23, Year 2021 > Number 18, September








Tunthanathip T, Ratanalert S, Sae-Heng S, Oearsakul T, Sakarunchai I, Kaewborisutsakul A, Chotsampancharoen T, Intusoma U, Kitkhuandee A, Vaniyapong T.
Prognostic factors and clinical nomogram predicting survival in high-grade glioma.
J Cancer Res Ther. 2021 Jul-Sep;17(4):1052-1058. doi: 10.4103/jcrt.JCRT_233_19. Online 2020 Nov 3. PMID: 34528563. Retrospective analysis.




Li C, Li W, Dai S, Sharma A, Sharma HS, Wu Y.
Targeted therapy with anlotinib for a leptomeningeal spread recurrent glioblastoma patient.
Prog Brain Res. 2021;265:407-414. doi: 10.1016/bs.pbr.2021.06.018. Online 2021 Aug 13. PMID: 34560927. Case report;




Hassan U, Latif M, Yousaf I, Bin Anees S, Mushtaq S, Akhtar N, Loya A.
Morphological Spectrum and Survival Analysis of Diffuse Midline Glioma With H3K27M Mutation.
Cureus. 2021 Aug 17;13(8):e17267⍈. doi: 10.7759/cureus.17267. PMID: 34540489. Retrospective analysis.




MacIver CL, Busaidi AA, Ganeshan B, Maynard JA, Wastling S, Hyare H, Brandner S, Markus JE, Lewis MA, Groves AM, Cwynarski K, Thust SC.
Filtration-Histogram Based Magnetic Resonance Texture Analysis (MRTA) for the Distinction of Primary Central Nervous System Lymphoma and Glioblastoma.
J Pers Med. 2021 Aug 31;11(9):876. doi: 10.3390/jpm11090876. PMID: 34575653. Retrospective analysis.




Minturn JE, Mochizuki AY, Partap S, Belasco JB, Lange BJ, Li Y, Phillips PC, Gibbs IC, Fisher PG, Fisher MJ, Janss AJ.
A Pilot Study of Low-Dose Craniospinal Irradiation in Patients With Newly Diagnosed Average-Risk Medulloblastoma.
Front Oncol. 2021 Sep 2;11:744739. doi: 10.3389/fonc.2021.744739. PMID: 34540703. Phase 2 trial.




Wang ZH, Xiao XL, Zhang ZT, He K, Hu F.
A Radiomics Model for Predicting Early Recurrence in Grade II Gliomas Based on Preoperative Multiparametric Magnetic Resonance Imaging.
Front Oncol. 2021 Sep 2;11:684996. doi: 10.3389/fonc.2021.684996. PMID: 34540662. Retrospective analysis.




Di Bonaventura R, Montano N, Giordano M, Gessi M, Gaudino S, Izzo A, Mattogno PP, Stumpo V, Caccavella VM, Giordano C, Lauretti L, Colosimo C, D'Alessandris QG, Pallini R, Olivi A.
Reassessing the Role of Brain Tumor Biopsy in the Era of Advanced Surgical, Molecular, and Imaging Techniques-A Single-Center Experience with Long-Term Follow-Up.
J Pers Med. 2021 Sep 12;11(9):909. doi: 10.3390/jpm11090909. PMID: 34575685. Retrospective analysis.




Fujii Y, Ogiwara T, Watanabe G, Hanaoka Y, Goto T, Hongo K, Horiuchi T.
Intraoperative low-field magnetic resonance imaging-guided tumor resection in glioma surgery: Pros and cons.
J Nippon Med Sch. 2021 Sep 14. doi: 10.1272/jnms.JNMS.2022_89-301. Online ahead of print. PMID: 34526467. Retrospective analysis.




Lautenschlaeger FS, Dumke R, Schymalla M, Hauswald H, Carl B, Stein M, Keber U, Jensen A, Engenhart-Cabillic R, Eberle F.
Comparison of carbon ion and photon reirradiation for recurrent glioblastoma.
Strahlenther Onkol. 2021 Sep 14. doi: 10.1007/s00066-021-01844-8. Online ahead of print. PMID: 34523017. Retrospective analysis.




Smith HL, Collins J, Park D, Darlington W, Quezado M, Aldape K, Warnke P, Pytel P.
Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants.
J Neuropathol Exp Neurol. 2021 Sep 15:nlab093. doi: 10.1093/jnen/nlab093. Online ahead of print. PMID: 34524458. Case series.




Morscher RJ, Brard C, Berlanga P, Marshall LV, André N, Rubino J, Aerts I, De Carli E, Corradini N, Nebchi S, Paoletti X, Mortimer P, Lacroix L, Pierron G, Schleiermacher G, Vassal G, Geoerger B.
First-in-child phase I/II study of the dual mTORC1/2 inhibitor vistusertib (AZD2014) as monotherapy and in combination with topotecan-temozolomide in children with advanced malignancies: arms E and F of the AcSé-ESMART trial.
Eur J Cancer. 2021 Sep 17;157:268-277. doi: 10.1016/j.ejca.2021.08.010. Online ahead of print. PMID: 34543871. Phase 1/2 trial;




Sun P, Fan DJ, Fan T, Li X, Qi XL, Zhao XG, Gai QF.
A Prospective Clinical Study on MGMT Protein Expression and the Effect of Gene Promoter Methylation on Sensitivity to Chemotherapeutics in Spinal Glioma.
J Inflamm Res. 2021 Sep 18;14:4777-4784. doi: 10.2147/JIR.S321790. PMID: 34566423. Prospective study.




Yamamuro S, Takahashi M, Satomi K, Sasaki N, Kobayashi T, Uchida E, Kawauchi D, Nakano T, Fujii T, Narita Y, Kondo A, Wada K, Yoshino A, Ichimura K, Tomiyama A.
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
Cancer Sci. 2021 Sep 18. doi: 10.1111/cas.15141. Online ahead of print. PMID: 34536314. Laboratory investigation.




Deng MY, Sturm D, Pfaff E, Sill M, Stichel D, Balasubramanian GP, Tippelt S, Kramm C, Donson AM, Green AL, Jones C, Schittenhelm J, Ebinger M, Schuhmann MU, Jones BC, van Tilburg CM, Wittmann A, Golanov A, Ryzhova M, Ecker J, Milde T, Witt O, Sahm F, Reuss D, Sumerauer D, Zamecnik J, Korshunov A, von Deimling A, Pfister SM, Jones DTW.
Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B.
Nat Commun. 2021 Sep 20;12(1):5530. doi: 10.1038/s41467-021-25708-y. PMID: 34545083. Laboratory investigation.




DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL.
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
Nat Commun. 2021 Sep 20;12(1):5531. doi: 10.1038/s41467-021-25709-x. PMID: 34545084. Laboratory investigation.



Lombardi G, Caccese M, Padovan M, Cerretti G, Pintacuda G, Manara R, Di Sarra F, Zagonel V.
Regorafenib in Recurrent Glioblastoma Patients: A Large and Monocentric Real-Life Study.
Cancers (Basel). 2021 Sep 21;13(18):4731. doi: 10.3390/cancers13184731. PMID: 34572958. Retrospective analysis.




Varlet P, Bouffet E, Casanova M, Giangaspero F, Antonelli M, Hargrave D, Ladenstein R, Pearson A, Hawkins C, König FB, Rüschoff J, Schmauch C, Bühnemann C, Garin-Chesa P, Schweifer N, Uttenreuther-Fischer M, Gibson N, Ittrich C, Krämer N, Solca F, Stolze B, Geoerger B.
Comprehensive analysis of the ErbB receptor family in pediatric nervous system tumors and rhabdomyosarcoma.
Pediatr Blood Cancer. 2021 Sep 21:e29316. doi: 10.1002/pbc.29316. Online ahead of print. PMID: 34546642. Laboratory investigation.




Carvalho DM, Richardson PJ, Olaciregui N, Stankunaite R, Lavarino C, Molinari V, Corley EA, Smith DP, Ruddle R, Donovan A, Pal A, Raynaud FI, Temelso S, Mackay A, Overington JP, Phelan A, Sheppard D, Mackinnon A, Zebian B, Al-Sarraj S, Merve A, Pryce J, Grill J, Hubank M, Cruz O, Morales La Madrid A, Mueller S, Carcaboso AM, Carceller F, Jones C.
Repurposing vandetanib plus everolimus for the treatment of ACVR1-mutant diffuse intrinsic pontine glioma.
Cancer Discov. 2021 Sep 22:candisc.1201.2020. doi: 10.1158/2159-8290.CD-20-1201. Online ahead of print. PMID: 34551970. Clinical investigation.




Asuzu DT, Bunevicius A, Kormath Anand R, Suleiman M, Nabeel AM, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Chytka T, Liščák R, Sheehan K, Sheehan D, Perez Caceres M, Mathieu D, Lee CC, Yang HC, Picozzi P, Franzini A, Attuati L, Speckter H, Olivo J, Patel S, Cifarelli CP, Cifarelli DT, Hack JD, Strickland BA, Zada G, Chang EL, Fakhoury KR, Rusthoven CG, Warnick RE, Sheehan JP.
Clinical and radiologic outcomes after stereotactic radiosurgery for meningiomas in direct contact with the optic apparatus: an international multicenter study.
J Neurosurg. 2021 Sep 24:1-7. doi: 10.3171/2021.3.JNS21328. Online ahead of print. PMID: 34560648. Retrospective analysis;




Cheng L, Wang L, Yao Q, Ma L, Duan W, Guan J, Zhang C, Wang K, Liu Z, Wang X, Wang Z, Wu H, Chen Z, Jian F.
Clinicoradiological characteristics of primary spinal cord H3 K27M-mutant diffuse midline glioma.
J Neurosurg Spine. 2021 Sep 24:1-12. doi: 10.3171/2021.4.SPINE2140?. Online ahead of print. PMID: 34560639. Clinical investigation;




Medikonda R, Patel K, Jackson C, Saleh L, Srivastava S, Feghali J, Mohan A, Pant A, Jackson CM, Weingart J, Mukherjee D, Bettegowda C, Gallia GL, Brem H, Lim M.
The safety and efficacy of dexamethasone in the perioperative management of glioma patients.
J Neurosurg. 2021 Sep 24:1-8. doi: 10.3171/2021.4.JNS204127. Online ahead of print. PMID: 34560653. Retrospective analysis;




Fletcher-Sananikone E, Kanji S, Tomimatsu N, Macedo Di Cristofaro LF, Kollipara RK, Saha D, Floyd JR, Sung P, Hromas R, Burns TC, Kittler R, Habib AA, Mukherjee B, Burma S.
Elimination of radiation-induced senescence in the brain tumor microenvironment attenuates glioblastoma recurrence.
Cancer Res. 2021 Sep 27:canres.0752.2021. doi: 10.1158/0008-5472.CAN-21-0752. Online ahead of print. PMID: 34580063. Laboratory investigation;




Aoki T, Kagawa N, Sugiyama K, Wakabayashi T, Arakawa Y, Yamaguchi S, Tanaka S, Ishikawa E, Muragaki Y, Nagane M, Nakada M, Suehiro S, Hata N, Kuroda J, Narita Y, Sonoda Y, Iwadate Y, Natsumeda M, Nakazato Y, Minami H, Hirata Y, Hagihara S, Nishikawa R.
Efficacy and safety of nivolumab in Japanese patients with first recurrence of glioblastoma: an open-label, non-comparative study.
Int J Clin Oncol. 2021 Sep 29. doi: 10.1007/s10147-021-02028-1. Online ahead of print. PMID: 34586548. Clinical investigation.






***********************