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Anticonvulsant Pathology

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Brain Tumors


Glantz MJ, Cole BF, Friedberg MH, Lathi E, Choy H, Furie K, Akerley W, Wahlberg L, Lekos A, Louis S
A randomized, blinded, placebo-controlled trial of divalproex sodium prophylaxis in adults with newly diagnosed brain tumors
Neurology 1996 Apr;46(4):985-91

Maschio M, Albani F, Jandolo B, Zarabla A, Contin M, Dinapoli L, Fabi A, Pace A, Baruzzi A
Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy
J Neurooncol. 2008 Jul 9; [Epub ahead of print]
 Abstract


Glioblastoma


K. A. Jaeckle, K. Ballman, J. Uhm, J. O'Fallon, P. Schomberg, B. Scheithauer, C. Giannini, P. J. Flynn, J. Buckner
Comparison of survival endpoints in glioblastoma patients receiving or not receiving enzyme-inducing anticonvulsants in NCCTG Trials
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1525 

Neyns B, Hoorens A, Stupp R.
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide
Acta Neurol Belg. 2008 Dec;108(4):131-4
  Abstract


Gliomas


Bourg V, Lebrun C, Chichmanian RM, Thomas P, Frenay M
Nitroso-urea-cisplatin-based chemotherapy associated with valproate: increase of haematologic toxicity.
Ann Oncol 2001 Feb;12(2):217-9
  Abstract |   Reprint |   Related articles


Gliomas (Low-Grade)


Klein M, Engelberts NH, van der Ploeg HM, Kasteleijn-Nolst Trenite DG, Aaronson NK, Taphoorn MJ, Baaijen H, Vandertop WP, Muller M, Postma TJ, Heimans JJ
Epilepsy in low-grade gliomas: the impact on cognitive function and quality of life

Ann Neurol. 2003 Oct;54(4):514-20.

Klein M, Heimans JJ, Aaronson NK, van der Ploeg HM, Grit J, Muller M, Postma TJ, Mooij JJ, Boerman RH, Beute GN, Ossenkoppele GJ, van Imhoff GW, Dekker AW, Jolles J, Slotman BJ, Struikmans H, Taphoorn MJ
Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study

Lancet. 2002 Nov 2;360(9343):1361-8. 


Epileptic Patients


Alan B. Ettinger, MD
Psychotropic effects of antiepileptic drugs
Neurology, Volume 67, Number 11, December 12, 2006

Luef G, Abraham I, Hoppichler F, Trinka E, Unterberger I, Bauer G, Lechleitner M
Increase in postprandial serum insulin levels in epileptic patients with valproic acid therapy

Metabolism 2002 Oct;51(10):1274-8


Gross-Tsur V, Shalev RS
Reversible language regression as an adverse effect of topiramate treatment in children
Neurology. 2004 Jan 27;62(2):299-300.

G Hayman, A Bansal
Antibody deficiency associated with carbamazepine
BMJ 2002;325:1213 (23 November)
(HTML Full Text)

Nathalie Jette, MD, Tim Veregin, BSP and Alan Guberman, MD
Carbamazepine-induced hypertension
Neurology 2002 Jul 23;59(2):275-6
 Abstract

Meador KJ, Baker GA, Browning N, Clayton-Smith J, Combs-Cantrell DT, Cohen M, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW; NEAD Study Group
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
N Engl J Med. 2009 Apr 16;360(16):1597-605
  Abstract

Meador KJ
Effects of in utero antiepileptic drug exposure
Epilepsy Curr. 2008 Nov-Dec;8(6):143-7
  Abstract |   Full Text |   Reprint

A. M. Pack, MD, M. J. Morrell, MD, A. Randall, D. J. McMahon, MSc and E. Shane, MD
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy
Neurology, April 29 2008, Volume 70, CNO 18
 Abstract |  News

Pack AM
Therapy insight: clinical management of pregnant women with epilepsy
Nat Clin Pract Neurol. 2006 Apr;2(4):190-200. Review
 Abstract |  Full Text |  Reprint

Trinka E, Dilitz E, Unterberger I, Luef G, Deisenhammer F, Niedermuller U, Thaler C, Bauer G
Non convulsive status epilepticus after replacement of valproate with lamotrigine

J Neurol 2002 Oct;249(10):1417-22



Metastatic Tumors


Aguiar D, Pazo R, Duran I, Terrasa J, Arrivi A, Manzano H, Martin J, Rifa J
Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider
J Neurooncol. 2004 Feb;66(3):345-50. (Abstract+)

S. Evans, N. Jooma, A. Kabir, L. Nedzi, E. Zakris, R. Mudad
Seizure prophylaxis in patients with brain metastases from solid tumors: Is phenytoin necessary?
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.8186

 

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