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Bevacizumab

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Contents


Laboratory Investigations


Ebos JM, Kerbel RS.
Antiangiogenic therapy: impact on invasion, disease progression, and metastasis.
Nat Rev Clin Oncol. 2011 Mar 1;8(4):210-21. Erratum in: Nat Rev Clin Oncol. 2011 Jun;8(6):316. Nat Rev Clin Oncol. 2011;8(4):221
  Abstract |
  Full text |   Reprint |   Related articles

Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, Inoue M, Bergers G, Hanahan D, Casanovas O.
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis.
Cancer Cell. 2009 Mar 3;15(3):220-31°
  Abstract |   Reprint |   Related articles


Astrocytoma


Chamberlain MC, Johnston S
Salvage chemotherapy with bevacizumab for recurrent alkylator-refractory anaplastic astrocytoma
J Neurooncol. 2009 Feb;91(3):359-67. Epub 2008 Oct 25
  Abstract

Sathornsumetee S, Cao Y, Marcello JE, Herndon JE 2nd, McLendon RE, Desjardins A, Friedman HS, Dewhirst MW, Vredenburgh JJ, Rich JN
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan
J Clin Oncol. 2008 Jan 10;26(2):271-8
  Abstract


Embryonal Tumors


Bevacizumab, Celecoxib,  Cyclophosphamide, Etoposide, Fenofibrate, Thalidomide

Peyrl A, Chocholous M, Kieran MW, Azizi AA, Prucker C, Czech T, Dieckmann K, Schmook MT, Haberler C, Leiss U, Slavc I.
Antiangiogenic metronomic therapy for children with recurrent embryonal brain tumors.
Pediatr Blood Cancer. 2011 Dec 6;. [Epub ahead of print]
  Abstract |   Related articles


Ependymoma


Green RM, Cloughesy TF, Stupp R, DeAngelis LM, Woyshner EA, Ney DE, Lassman AB.
Bevacizumab for recurrent ependymoma
Neurology. 2009 Nov 17;73(20):1677-80
  Abstract


Glioblastoma


Bähr O, Hattingen E, Rieger J, Steinbach JP.
Bevacizumab-induced tumor calcifications as a surrogate marker of outcome in patients with glioblastoma.
Neuro Oncol. 2011 Sep;13(9):1020-9. Epub 2011 Jul 31.
  Abstract |   Related articles

Chamberlain MC.
Treatment of Glioblastoma with Bevacizumab: Has a New Standard Therapy been Defined?
CNS Drugs. 2011 Oct 1;25(10):815-8.
  Abstract |   Related articles

Chinot OL, de La Motte Rouge T, Moore N, Zeaiter A, Das A, Phillips H, Modrusan Z, Cloughesy T.
AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.
Adv Ther. 2011 Apr;28(4):334-40. Epub 2011 Mar 14.
  Abstract |   Reprint |   Related articles

Clark AJ, Lamborn KR, Butowski NA, Chang SM, Prados MD, Clarke JL, McDermott MW, Parsa AT, Berger MS, Aghi MK.
Neurosurgical management and prognosis of patients with glioblastoma that progress during bevacizumab treatment.
Neurosurgery. 2011 Aug 9. [Epub ahead of print]
  Abstract |   Related articles

Desjardins A, Reardon DA, Peters KB, Herndon II JE, Kirkpatrick JP, Friedman HS and Vredenburgh JJ
Survival And Toxicity Update Of The Phase 2 Trial Of Bevacizumab (Bv) In Combination With Temozolomide (Tmz) And Radiation Therapy (Rt) Followed By Bv, Tmz, And Irinotecan (Cpt-11) For Newly Diagnosed Glioblastoma Multiforme (Gbm) Patients
Abstracts from the 15th Annual Meeting of the Society for Neuro-Oncology (SNO), November 18–21, 2010, Montreal, Quebec, Canada
  Abstract |   News

Jakobsen JN, Hasselbalch B, Stockhausen MT, Lassen U, Poulsen HS.
Irinotecan and bevacizumab in recurrent glioblastoma multiforme.
Expert Opin Pharmacother. 2011 Apr;12(5):825-33.
  Abstract |   Related articles

Kilickap S, Oztoprak I, Yucel B.
Complete remission after bevacizumab plus temozolomide in a patient with recurrent glioblastoma multiforme.
Acta Oncol. 2011 Dec 27;. [Epub ahead of print]
  Abstract |   Related articles

J. Kirkpatrick, A. Desjardins, J. J. Vredenburgh, J. A. Quinn, J. N. Rich, S. Sathornsumetee, S. Gururangan, A. H. Friedman, H. S. Friedman, D. A. Reardon
Combination of bevacizumab, a monoclonal antibody to vascular endothelial growth factor (VEGF), and temozolomide: Study of cases
Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings (Post-Meeting Edition).
Vol 24, No 18S (June 20 Supplement), 2006: 11522
  Abstract |   News

Furuse M, Kawabata S, Kuroiwa T, Miyatake SI.
Repeated treatments with bevacizumab for recurrent radiation necrosis in patients with malignant brain tumors: a report of 2 cases
J Neurooncol. 2010 Aug 7;. [Epub ahead of print]
  Abstract

Lai A, Tran A, Nghiemphu PL, Pope WB, Solis OE, Selch M, Filka E, Yong WH, Mischel PS, Liau LM, Phuphanich S, Black K, Peak S, Green RM, Spier CE, Kolevska T, Polikoff J, Fehrenbacher L, Elashoff R, Cloughesy T.
Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme.
J Clin Oncol. 2010 Dec 6. [Epub ahead of print]
  Abstract |   News |   Related articles

Lai A, Filka E, McGibbon B, Nghiemphu PL, Graham C, Yong WH, Mischel P, Liau LM, Bergsneider M, Pope W, Selch M, Cloughesy T.
Phase II Pilot Study of Bevacizumab in Combination With Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability
Int J Radiat Oncol Biol Phys. 2008 Mar 20; [Epub ahead of print]
  Abstract

Laigle-Donadey F, Dehais C, Mazeron JJ, Sanson M
Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas
Bull Cancer. 2009 Mar 1;96(3):291-297
  Abstract

Li L, Quang TS, Gracely EJ, Kim JH, Emrich JG, Yaeger TE, Jenrette JM, Cohen SC, Black P, Brady LW.
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme
J Neurosurg. 2010 Mar 26;. [Epub ahead of print]
  Abstract

Lou E, Turner S, Sumrall A, Reardon DA, Desjardins A, Peters KB, Sampson JH, Friedman HS, Vredenburgh JJ.
Bevacizumab-Induced Reversible Posterior Leukoencephalopathy Syndrome and Successful Retreatment in a Patient With Glioblastoma.
J Clin Oncol. 2011 Sep 6. [Epub ahead of print]
  Abstract |   Related articles

Mathieu V, De Nève N, Le Mercier M, Dewelle J, Gaussin JF, Dehoux M, Kiss R, Lefranc F
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model
Neoplasia. 2008 Dec;10(12):1383-92
  Abstract |   Full Text |   Reprint

Moustakas A, Kreisl TN.
New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab
Onco Targets Ther. 2010 Jun 24;3:27-38
  Abstract |   Full Text |   Reprint

Narayana A, Gruber D, Kunnakkat S, Golfinos JG, Parker E, Raza S, Zagzag D, Eagan P, Gruber ML.
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
J Neurosurg. 2011 Oct 28;. [Epub ahead of print]
  Abstract |   Related articles

Omuro AM, Delattre JY
What is the place of bevacizumab and irinotecan in the treatment of glioblastoma and other malignant gliomas?
Curr Opin Neurol. 2008 Dec;21(6):717-719
  Abstract

Vredenburgh JJ, Desjardins A, Reardon DA, Peters KB, Herndon JE 2nd, Marcello JE, Kirkpatrick J, Sampson JH, Bailey L, Threatt S, Friedman AH, Bigner DD, Friedman HS.
The Addition of Bevacizumab to Standard Radiation Therapy and Temozolomide Followed by Bevacizumab, Temozolomide and Irinotecan for Newly Diagnosed Glioblastoma.
Clin Cancer Res. 2011 Apr 29. [Epub ahead of print]
  Abstract |   Related articles


Recurrent Tumors


Ali SA, McHayleh WM, Ahmad A, Sehgal R, Braffet M, Rahman M, Bejjani G, Friedland DM.
Bevacizumab and irinotecan therapy in glioblastoma multiforme: a series of 13 cases
J Neurosurg. 2008 Aug;109(2):268-72
  Abstract

Chamberlain MC.
Bevacizumab for the treatment of recurrent glioblastoma.
Clin Med Insights Oncol. 2011;5:117-29. Epub 2011 May 2.
  Abstract |   Reprint |   Related articles

Chamberlain MC, Johnston SK.
Recurrent spinal cord glioblastoma: salvage therapy with bevacizumab
J Neurooncol. 2010 Aug 1;. [Epub ahead of print]
  Abstract

Chamberlain MC, Lassman AB, Iwamoto FM.
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma.
Neurology. 2010 Apr 13;74(15):1239-41.
  Abstract |   Related articles

Chamberlain MC, Johnston SK
Salvage therapy with single agent bevacizumab for recurrent glioblastoma
J Neurooncol. 2009 Jul 11. [Epub ahead of print]
  Abstract

Chamberlain MC
Bevacizumab Plus Irinotecan in Recurrent Glioblastoma
J Clin Oncol. 2008 Feb 20;26(6):1012-1013
  Abstract |   Full Text |   Reprint

Chowdhary S, Wong ET
Bevacizumab combined with irinotecan for recurrent glioblastoma multiforme-improvement over available therapy?
Nat Clin Pract Neurol. 2008 Jan 22. [Epub ahead of print]
  Abstract

Clark AJ, Butowski NA, Chang SM, Prados MD, Clarke J, Polley MY, Sughrue ME, McDermott MW, Parsa AT, Berger MS, Aghi MK.
Impact of bevacizumab chemotherapy on craniotomy wound healing.
J Neurosurg. 2011 Jun;114(6):1609-16. Epub 2010 Dec 10.
  Abstract

Desjardins A, Reardon DA, Coan A, Marcello J, Herndon JE 2nd, Bailey L, Peters KB, Friedman HS, Vredenburgh JJ.
Bevacizumab and daily temozolomide for recurrent glioblastoma.
Cancer. 2011 Jul 26. [Epub ahead of print]
  Abstract |   Related articles

Francesconi AB, Dupre S, Matos M, Martin D, Hughes BG, Wyld DK, Lickliter JD
Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme
J Clin Neurosci. 2010 Jun 9;. [Epub ahead of print]
  Abstract

Friedman HS, Prados MD, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Huang J, Zheng M, Cloughesy T
Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
J Clin Oncol. 2009 Aug 31. [Epub ahead of print]
  Abstract

Hasselbalch B, Eriksen JG, Broholm H, Christensen IJ, Grunnet K, Horsman MR, Poulsen HS, Stockhausen MT, Lassen U.
Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan
APMIS. 2010 Aug;118(8):585-94. Published Online: 1 Jun 2010
  Abstract

Khasraw M, Holodny A, Goldlust SA, Deangelis LM.
Intracranial hemorrhage in patients with cancer treated with bevacizumab: the Memorial Sloan-Kettering experience.
Ann Oncol. 2011 May 4;. [Epub ahead of print]
  Abstract |   Related articles

Kreisl TN, Kim L, Moore K, Duic P, Royce C, Stroud I, Garren N, Mackey M, Butman JA, Camphausen K, Park J, Albert PS, Fine HA
Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma
J Clin Oncol. 2008 Dec 29; [Epub ahead of print]
  Abstract

Lassman AB, Iwamoto FM, Gutin PH, Abrey LE.
Patterns of relapse and prognosis after bevacizumab (BEV) failure in recurrent glioblastoma (GBM).
2008 ASCO Annual Meeting. J Clin Oncol. 26: 2008 (May 20 suppl; abstr 2028)
  Abstract

Nghiemphu PL, Liu W, Lee Y, Than T, Graham C, Lai A, Green RM, Pope WB, Liau LM, Mischel PS, Nelson SF, Elashoff R, Cloughesy TF
Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience
Neurology. 2009 Apr 7;72(14):1217-22
  Abstract

Moen MD
Bevacizumab: in previously treated glioblastoma
Drugs. 2010;70(2):181-9
  Abstract

Norden AD.
Bevacizumab Failure in Recurrent Glioblastoma.
Journal Watch Neurology. 2010 Jan 12.
  Abstract

Norden AD, Drappatz J, Muzikansky A, David K, Gerard M, McNamara MB, Phan P, Ross A, Kesari S, Wen PY
An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma.
J Neurooncol. 2009 Apr;92(2):149-55. Epub 2008 Nov 29.
  Abstract |
  Reprint |   Related articles

Park KJ, Kano H, Iyer A, Liu X, Niranjan A, Flickinger JC, Lieberman FS, Lunsford LD, Kondziolka D.
Salvage gamma knife stereotactic radiosurgery followed by bevacizumab for recurrent glioblastoma multiforme: a case-control study.
J Neurooncol. 2011 Nov 5;. [Epub ahead of print]
  Abstract |   Related articles

Reardon DA, Desjardins A, Peters KB, Gururangan S, Sampson JH, McLendon RE, Herndon JE 2nd, Bulusu A, Threatt S, Friedman AH, Vredenburgh JJ, Friedman HS.
Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab
naïve, recurrent glioblastoma.
J Neurooncol. 2011 Oct 11;. [Epub ahead of print]
  Abstract |   Related articles

Reardon DA, Desjardins A, Peters KB, Vredenburgh JJ, Gururangan S, Sampson JH, McLendon RE, Herndon JE 2nd, Coan A, Threatt S, Friedman AH, Friedman HS.
Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
Cancer. 2011 May 16. doi: 10.1002/cncr.26188. [Epub ahead of print]
  Abstract |   Related articles

James J. Vredenburgh, Annick Desjardins, David A. Reardon, Henry S. Friedman
In Reply
Journal of Clinical Oncology, Vol 26, No 6 (February 20), 2008: pp. 1013. DOI: 10.1200/JCO.2007.15.1746
  Abstract |   Full Text |   Reprint

Vredenburgh JJ, Desjardins A, Herndon JE 2nd, Marcello J, Reardon DA, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Sampson J, Wagner M, Bailey L, Bigner DD, Friedman AH, Friedman HS.
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
J Clin Oncol. 2007 Oct 20;25(30):4722-9.
  Abstract |   Full Text |   Reprint

Wefel JS, Cloughesy T, Zazzali JL, Zheng M, Prados M, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Das A, Friedman HS.
Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab.
Neuro Oncol. 2011 May 9;. [Epub ahead of print]
  Abstract |   Related articles

Wick W, Weller M, van den Bent M, Stupp R
Bevacizumab and Recurrent Malignant Gliomas: A European Perspective
J Clin Oncol. 2010 Mar 8. [Epub ahead of print]
  Abstract |   Reprint

Wong ET, Brem S.
Taming glioblastoma: targeting angiogenesis.
J Clin Oncol. 2007 Oct 20;25(30):4705-6.
  Abstract |   Reprint |   Related articles


Glioma (High-Grade)


Norden AD, Bartolomeo J, Tanaka S, Drappatz J, Ciampa AS, Doherty LM, Lafrankie DC, Ruland S, Quant EC, Beroukhim R, Wen PY.
Safety of concurrent bevacizumab therapy and anticoagulation in glioma patients.
J Neurooncol. 2011 Jun 26. [Epub ahead of print]
  Abstract |   Related articles

von Baumgarten LD, Brucker D, Tirniceru AL, Kienast Y, Grau S, Burgold S, Herms J, Winkler F.
Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells.
Clin Cancer Res. 2011 Jul 25. [Epub ahead of print]
  Abstract |   Related articles


Recurrent Tumors


Bokstein F, Shpigel S, Blumenthal DT
Treatment with bevacizumab and irinotecan for recurrent high-grade glial tumors
Cancer. 2008 May 15;112(10):2267-73
  Abstract

Chamberlain MC
Emerging clinical principles on the use of bevacizumab for the treatment of malignant gliomas
Cancer. 2010 May 28;. [Epub ahead of print]
  Abstract

Cuneo KC, Vredenburgh JJ, Sampson JH, Reardon DA, Desjardins A, Peters KB, Friedman HS, Willett CG, Kirkpatrick JP.
Safety and Efficacy of Stereotactic Radiosurgery and Adjuvant Bevacizumab in Patients with Recurrent Malignant Gliomas.
Int J Radiat Oncol Biol Phys. 2011 Apr 12;. [Epub ahead of print]
  Abstract |   Related articles

Desjardins A, Reardon DA, Herndon JE 2nd, Marcello J, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Sampson J, Bailey L, Bigner DD, Friedman AH, Friedman HS, Vredenburgh JJ.
Bevacizumab Plus Irinotecan in Recurrent WHO Grade 3 Malignant Gliomas
Clin Cancer Res. 2008 Nov 1;14(21):7068-73
  Abstract

Eoli M, Calleri A, Cuppini L, Anghileri E, Pellegatta S, Prodi E, Bruzzone MG, Bertolini F, Finocchiaro G.
Circulating endothelial cells and progenitors in recurrent high-grade gliomas treated with bevacizumab and irinotecan.
J Clin Oncol. 2011 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 29, No 15_suppl (May 20 Supplement), 2011:2044
  Abstract

Eoli M, Calleri A, Cuppini L, Mancuso P, Prodi E, Pellegatta S, Solero CL, Bruzzone MG, Bertolini F, Finocchiaro G.
Levels of circulating endothelial cells in relapsing glioblastoma patients responding to bevacizumab.
J Clin Oncol. 2010 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 28, No 15S (May 20 Supplement), 2010: 2067
  Abstract

Gutin PH, Iwamoto FM, Beal K, Mohile NA, Karimi S, Hou CNO, Lymberis S, Yamada Y, Chang J, Abrey LE
Safety and Efficacy of Bevacizumab with Hypofractionated Stereotactic Irradiation for Recurrent Malignant Gliomas
Int J Radiat Oncol Biol Phys. 2009 Jan 23. [Epub ahead of print]
  Abstract

Hutterer M, Nowosielski M, Putzer D, Waitz D, Tinkhauser G, Kostron H, Muigg A, Virgolini IJ, Staffen W, Trinka E, Gotwald T, Jacobs AH, Stockhammer G.
O-(2-18F-Fluoroethyl)-L-Tyrosine PET Predicts Failure of Antiangiogenic Treatment in Patients with Recurrent High-Grade Glioma.
J Nucl Med. 2011 Jun;52(6):856-64.
  Abstract |   Related articles

Iwamoto FM, Fine HA.
Bevacizumab for malignant gliomas.
Arch Neurol. 2010 Mar;67(3):285-8.
  Abstract |   Reprint |   Related articles

Kreisl TN, Zhang W, Odia Y, Shih JH, Butman JA, Hammoud D, Iwamoto FM, Sul J, Fine HA.
A phase II trial of single-agent bevacizumab in patients with recurrent anaplastic glioma.
Neuro Oncol. 2011 Aug 24. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Lorgis V, Maura G, Coppa G, Hassani K, Taillandier L, Chauffert B, Apetoh L, Ladoire S, Ghiringhelli F.
Relation between bevacizumab dose intensity and high-grade glioma survival: a retrospective study in two large cohorts.
J Neurooncol. 2011 Nov 11;. [Epub ahead of print]
  Abstract |   Related articles

Narayana A, Kelly P, Golfinos J, Parker E, Johnson G, Knopp E, Zagzag D, Fischer I, Raza S, Medabalmi P, Eagan P, Gruber ML
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival
J Neurosurg. 2008 Oct 3. [Epub ahead of print]
  Abstract

Niyazi M, Ganswindt U, Schwarz SB, Kreth FW, Tonn JC, Geisler J, la Fougère C, Ertl L, Linn J, Siefert A, Belka C.
Irradiation and Bevacizumab in High-Grade Glioma Retreatment Settings.
Int J Radiat Oncol Biol Phys. 2010 Oct 27. [Epub ahead of print]
  Abstract |   Related articles

Norden AD, Young GS, Setayesh K, Muzikansky A, Klufas R, Ross GL, Ciampa AS, Ebbeling LG, Levy B, Drappatz J, Kesari S, Wen PY
Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence
Neurology. 2008 Mar 4;70(10):779-87
  Abstract |   Full Text |   Reprint

Peak SJ, Levin VA.
Role of bevacizumab therapy in the management of glioblastoma.
Cancer Manag Res. 2010 Apr 22;2:97-104.
  Abstract |   Reprint


Raizer JJ, Grimm S, Chamberlain MC, Nicholas MK, Chandler JP, Muro K, Dubner S, Rademaker AW, Renfrow J, Bredel M
A phase 2 trial of single-agent bevacizumab given in an every-3-week schedule for patients with recurrent high-grade gliomas
Cancer. 2010 Jul 27;. [Epub ahead of print]
  Abstract

Reardon DA, Desjardins A, Vredenburgh JJ, Gururangan S, Sampson JH, Sathornsumetee S, McLendon RE, Herndon JE 2nd, Marcello JE, Norfleet J, Friedman AH, Bigner DD, Friedman HS
Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study
Br J Cancer. 2009 Nov 17;. [Epub ahead of print]
  Abstract

Salmaggi A, Gaviani P, Botturi A, Lamperti E, Simonetti G, Ferrari D, Silvani A.
Bevacizumab at recurrence in high-grade glioma.
Neurol Sci. 2011 Oct 7. [Epub ahead of print]
  Abstract |   Related articles

Sathornsumetee S, Desjardins A, Vredenburgh JJ, McLendon RE, Marcello J, Herndon JE, Mathe A, Hamilton M, Rich JN, Norfleet JA, Gururangan S, Friedman HS, Reardon DA.
Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma
Neuro Oncol. 2010 Aug 17;. [Epub ahead of print]
  Abstract

Thompson EM, Dosa E, Kraemer DF, Neuwelt EA
Treatment with bevacizumab plus carboplatin for recurrent malignant glioma
Neurosurgery. 2010 Jul;67(1):87-93
  Abstract

Torcuator R, Zuniga R, Loutfi R, Mikkelsen T
Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report
J Neurooncol. 2009 Jan 13. [Epub ahead of print]
  Abstract

Verhoeff JJ, Lavini C, van Linde ME, Stalpers LJ, Majoie CB, Reijneveld JC, van Furth WR, Richel DJ
Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma
Ann Oncol (2010) 21 (8): 1723-1727.

  Abstract |   Reprint

J. J. Vredenburgh, A. Desjardins, J. E. Herndon, J. Quinn, J. Rich, S. Sathornsumetee, H. S. Friedman, D. Reardon, S. Gururangan, A. Friedman
Bevacizumab, a monoclonal antibody to vascular endothelial growth factor (VEGF), and irinotecan for treatment of malignant gliomas
Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings (Post-Meeting Edition).
Vol 24, No 18S (June 20 Supplement), 2006: 1506
  Abstract |   News

Wick A, Dörner N, Schäfer N, Hofer S, Heiland S, Schemmer D, Platten M, Weller M, Bendszus M, Wick W.
Bevacizumab does not increase the risk of remote relapse in malignant glioma.
Ann Neurol. 2011 Mar;69(3):586-92.
  Abstract |   Related articles

Xu T, Chen J, Lu Y, Wolff JE.
Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: a systematic review and survival-gain analysis
BMC Cancer. 2010 Jun 2;10(1):252. [Epub ahead of print]
  Abstract |   Full Text |   Reprint

Zuniga RM, Torcuator R, Jain R, Anderson J, Doyle T, Ellika S, Schultz L, Mikkelsen T
Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan
J Neurooncol. 2008 Oct 25. [Epub ahead of print]
  Abstract

Zustovich F, Lombardi G, Pastorelli D, Farina P, Furini L, Manara R, Palma MD, Rotilio A, Nicoletto O, Zagonel V.
Bevacizumab and glioblastomas, a single-centre experience: how disease history and characteristics may affect clinical outcome.
Anticancer Res. 2010 Dec;30(12):5213-6.
  Abstract |
  Related articles


Glioma (Low-Grade)


Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Prabhu S, Loghin M, Gilbert MR, Jackson EF.
Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system.
Int J Radiat Oncol Biol Phys. 2011 Apr 1;79(5):1487-95.
  Abstract |   Related articles


Metastatic Tumors


De Braganca KC, Janjigian YY, Azzoli CG, Kris MG, Pietanza MC, Nolan CP, Omuro AM, Holodny AI, Lassman AB.
Efficacy and safety of bevacizumab in active brain metastases from non-small cell lung cancer
J Neurooncol. 2010 May 4;. [Epub ahead of print]
  Abstract

Labidi SI, Bachelot T, Ray-Coquard I, Mosbah K, Treilleux I, Fayette J, Favier B, Galy G, Blay JY, Guastalla JP
Bevacizumab and Paclitaxel for breast cancer patients with central nervous system metastases: a case series
Clin Breast Cancer. 2009 May;9(2):118-21. Online Date May 11, 2009
  Abstract


Oligodendroglioma


Chamberlain MC, Johnston S
Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma
Cancer. 2009 Apr 15;115(8):1734-43
  Abstract

Taillibert S, Vincent LA, Granger B, Marie Y, Carpentier C, Guillevin R, Bellanger A, Mokhtari K, Rousseau A, Psimaras D, Dehais C, Sierra del Rio M, Meng Y, Laigle-Donadey F, Hoang-Xuan K, Sanson M, Delattre JY
Bevacizumab and irinotecan for recurrent oligodendroglial tumors
Neurology. 2009 May 5;72(18):1601-6
  Abstract


Pediatric Patients


Recurrent Tumors
Narayana A, Kunnakkat S, Chacko-Mathew J, Gardner S, Karajannis M, Raza S, Wisoff J, Weiner H, Harter D, Allen J.
Bevacizumab in recurrent high-grade pediatric gliomas
Neuro Oncol. 2010 Apr 2;. [Epub ahead of print
  Abstract

Recurrent Tumors
Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G.
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol. 2010 Nov 1. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Recurrent Tumors
Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G.
Erratum to: Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol. 2010 Nov 26. [Epub ahead of print]
  Abstract |   Reprint |   Related articles


Radiation Necrosis


Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Prabhu S, Loghin M, Gilbert MR, Jackson EF.
Randomized Double-Blind Placebo-Controlled Trial of Bevacizumab Therapy for Radiation Necrosis of the Central Nervous System
Int J Radiat Oncol Biol Phys. 2010 Apr 15 [Epub ahead of print] Available online 16 April 2010
  Abstract


Concerns


Aliabadi H, Vredenburgh JJ, Everson RG, Desjardins A, Friedman HS, McLendon RE, Tucci DL, Sampson JH
Bevacizumab fails to treat temporal paraganglioma: discussion and case illustration
J Neurooncol. 2010 Jul;98(3):427-30. Epub 2009 Dec 19
  Abstract |   Related articles

Chamberlain MC, Neuwelt EA, Thompson EM, Frenkel EP.
The paradoxical effect of bevacizumab in the therapy of malignant gliomas.
Neurology. 2011 Aug 23;77(8):803-4. Epub 2011 Apr 1.
  Abstract |   Full text |   Reprint |   Related articles

Gururangan S, Chi SN, Young Poussaint T, Onar-Thomas A, Gilbertson RJ, Vajapeyam S, Friedman HS, Packer RJ, Rood BN, Boyett JM, Kun LE
Lack of Efficacy of Bevacizumab Plus Irinotecan in Children With Recurrent Malignant Glioma and Diffuse Brainstem Glioma: A Pediatric Brain Tumor Consortium Study
J Clin Oncol. 2010 May 17;. [Epub ahead of print]
  Abstract

Iwamoto FM, Abrey LE, Beal K, Gutin PH, Rosenblum MK, Reuter VE, DeAngelis LM, Lassman AB
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
Neurology. 2009 Oct 13;73(15):1200-6
  Abstract

Kelly PJ, Dinkin MJ, Drappatz J, O'Regan KN, Weiss SE
Unexpected late radiation neurotoxicity following bevacizumab use: a case series
J Neurooncol. 2010 Aug 1;. [Epub ahead of print]
  Abstract

Narayana A, Kunnakkat SD, Medabalmi P, Golfinos J, Parker E, Knopp E, Zagzag D, Eagan P, Gruber D, Gruber ML.
Change in Pattern of Relapse After Antiangiogenic Therapy in High-Grade Glioma.
Int J Radiat Oncol Biol Phys. 2010 Dec 14. [Epub ahead of print]
  Abstract |
  Related articles

Pope WB, Xia Q, Paton VE, Das A, Hambleton J, Kim HJ, Huo J, Brown MS, Goldin J, Cloughesy T.
Patterns of progression in patients with recurrent glioblastoma treated with bevacizumab.
Neurology. 2011 Feb 1;76(5):432-7.
  Abstract |   Related articles

Ranpura V, Hapani S, Wu S.
Treatment-Related Mortality With Bevacizumab in Cancer Patients: A Meta-analysis.
JAMA. 2011 Feb 2;305(5):487-94.
  Abstract |   News |   Related articles

Thompson EM, Frenkel EP, Neuwelt EA.
The paradoxical effect of bevacizumab in the therapy of malignant gliomas.
Neurology. 2011 Jan 4;76(1):87-93.
  Abstract |   Reprint |   Related articles

Verhoeff JJ, van Tellingen O, Claes A, Stalpers LJ, van Linde ME, Richel DJ, Leenders WP, van Furth WR
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme
BMC Cancer. 2009 Dec 16;9(1):444. [Epub ahead of print]
  Abstract |   Reprint

Wick W, Wick A, Weiler M, Weller M.
Patterns of Progression in Malignant Glioma Following Anti-VEGF Therapy: Perceptions and Evidence.
Curr Neurol Neurosci Rep. 2011 Feb 1. [Epub ahead of print]
  Abstract |   Related articles

Wong ET, Brem S.
Taming Glioblastoma by Targeting Angiogenesis: 3 Years Later.
J Clin Oncol. 2010 Dec 6. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Zuniga RM, Torcuator R, Jain R, Anderson J, Doyle T, Schultz L, Mikkelsen T
Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma
J Neurooncol. 2010 Feb 12. [Epub ahead of print]
  Abstract |   Full Text |   Reprint

 

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