BRAINLIFE Brain Tumor Medical Database

Cancer Stem Cells

Home > Database > Stem Cells | Treatment > Cancer Stem Cells

Contents



Basic Science


Blough MD, Westgate MR, Beauchamp D, Kelly JJ, Stechishin O, Ramirez AL, Weiss S, Cairncross JG.
Sensitivity to temozolomide in brain tumor initiating cells
Neuro Oncol. 2010 Apr 13;. [Epub ahead of print]
  Abstract

Boman BM, Wicha MS
Cancer stem cells: a step toward the cure
J Clin Oncol. 2008 Jun 10;26(17):2795-9
  Abstract |   Full Text |   Reprint

Iwasaki H, Suda T
Cancer stem cells and their niche
Cancer Sci. 2009 Jul;100(7):1166-72. Epub 2009 Mar 30
  Abstract |   Full Text |   Reprint

Massard C, Deutsch E, Soria JC
Tumour stem cell-targeted treatment: elimination or differentiation
Ann Oncol. 2006 Nov;17(11):1620-4. Epub 2006 May 3
 Abstract |  Reprint

Maximilian Diehn and Michael F. Clarke
Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance
JNCI Journal of the National Cancer Institute, 98(24):1755-1757; 20 December 2006; doi:10.1093/jnci/djj505
Abstract | Full Text | Reprint

Jeremy N. Rich
Cancer Stem Cells in Radiation Resistance
Cancer Research 67, 8980-8984, October 1, 2007. doi: 10.1158/0008-5472.CAN-07-0895
Abstract | Reprint

Sanchez-Garcia I, Perez-Caro Maria
Cancer Stem Cells (CSC) ablation as a treatment strategy for cancer
AACR Meeting Abstracts, Apr 2006; 2006: 73
Abstract

Sharma V, Dixit D, Ghosh S, Sen E.
COX-2 regulates the proliferation of glioma stem like cells.
Neurochem Int. 2011 Jul 7. [Epub ahead of print]
  Abstract |   Related articles

Wu YY, Huang Q, Dong J, Lan Q
Correlation of stem cell niche to genesis and development of tumor stem cells
Ai Zheng. 2008 Jan;27(1):109-12
Abstract

Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
Nat Rev Drug Discov. 2009 Oct;8(10):806-23
  Abstract |   Reprint


Brain Tumors


Binello E, Germano IM.
Targeting glioma stem cells: a novel framework for brain tumors.
Cancer Sci. 2011 Aug 16. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Boockvar JA, Howard BM
Brain tumor stem cells: will understanding a new paradigm lead to improved therapies?
Expert Rev Neurother. 2008 Apr;8(4):511-4
 Abstract |  Full Text |  Reprint

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.
Chemical genetics reveals a complex functional ground state of neural stem cells
Nat Chem Biol. 2007 Apr 8; [Epub ahead of print]
PMID: 17417631 [PubMed - as supplied by publisher]
Full Text | Reprint

Guessous F, Zhang Y, Dipierro C, Marcinkiewicz L, Sarkaria J, Schiff D, Buchanan S, Abounader R.
An Orally Bioavailable c-Met Kinase Inhibitor Potently Inhibits Brain Tumor Malignancy and Growth
Anticancer Agents Med Chem. 2009 Dec 16;. [Epub ahead of print]
  Abstract

Jacques TS, Swales A, Brzozowski MJ, Henriquez NV, Linehan JM, Mirzadeh Z, O' Malley C, Naumann H, Alvarez-Buylla A, Brandner S
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes.
EMBO J. 2009 Nov 19. [Epub ahead of print]
  Abstract

Nicoletti F, Arcella A, Iacovelli L, Battaglia G, Giangaspero F, Melchiorri D. 
Metabotropic glutamate receptors: new targets for the control of tumor growth?
Trends Pharmacol Sci. 2007 Apr 11; [Epub ahead of print]
Abstract

Sandu N, Schaller B
Stem cell transplantation in brain tumors: A new field for molecular imaging?
Mol Med. 2010 Jun 30;. [Epub ahead of print]
  Abstract |   Reprint

Skog J, Edlund K, Bergenheim AT, Wadell G
Adenoviruses 16 and CV23 efficiently transduce human low-passage brain tumor and cancer stem cells
Mol Ther. 2007 Dec;15(12):2140-5. Epub 2007 Sep 18
 Abstract

Tu LC, Foltz G, Lin E, Hood L, Tian Q
Targeting stem cells-clinical implications for cancer therapy
Curr Stem Cell Res Ther. 2009 May;4(2):147-53
  Abstract

Patrizia Tunici, Ph.D., Dwain Irvin, Ph.D., M.P.H., Gentao Liu, Ph.D., Xiangpeng Yuan, Ph.D., Zeng Zhaohui, Ph.D., Hiushan Ng, M.S., and John S. Yu, M.D.
Brain tumor stem cells: new targets for clinical treatments?
Neurosurg Focus 20 (4):E27, April 2006
Abstract | Full Text | Reprint


Glioblastoma


Ahmed N, Salsman VS, Kew Y, Shaffer D, Powell S, Zhang YJ, Grossman RG, Heslop HE, Gottschalk S
HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
Clin Cancer Res. 2010 Jan 15;16(2):474-85.
  Abstract

Annabi B, Lachambre MP, Plouffe K, Sartelet H, Béliveau R
Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling
Mol Carcinog. 2009 Mar 26;. [Epub ahead of print]
  Abstract

Beier D, Röhrl S, Pillai DR, Schwarz S, Kunz-Schughart LA, Leukel P, Proescholdt M, Brawanski A, Bogdahn U, Trampe-Kieslich A, Giebel B, Wischhusen J, Reifenberger G, Hau P, Beier CP
Temozolomide preferentially depletes cancer stem cells in glioblastoma
Cancer Res. 2008 Jul 15;68(14):5706-15
 Abstract |  Reprint

Bertrand J, Begaud-Grimaud G, Bessette B, Verdier M, Battu S, Jauberteau MO
Cancer stem cells from human glioma cell line are resistant to Fas-induced apoptosis
Int J Oncol. 2009 Mar;34(3):717-27
  Abstract

Castriconi R, Daga A, Dondero A, Zona G, Poliani PL, Melotti A, Griffero F, Marubbi D, Spaziante R, Bellora F, Moretta L, Moretta A, Corte G, Bottino C
NK cells recognize and kill human glioblastoma cells with stem cell-like properties
J Immunol. 2009 Mar 15;182(6):3530-9
  Abstract

Chang CJ, Hsu CC, Yua MC, Chen KY, Tzao C, Wu WF, Chou HY, Lu KH, Chiou SH, Ma HI.
Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression
Biochem Biophys Res Commun. 2009 Jan 21. [Epub ahead of print]
  Abstract

Cheng L, Bao S, Rich JN.
Potential therapeutic implications of cancer stem cells in glioblastoma
Biochem Pharmacol. 2010 May 10;. [Epub ahead of print]
  Abstract

Eli E. Bar, Aneeka Chaudhry, Alex Lin, Xing Fan, Karisa Schreck, William Matsui, Sara Piccirillo, Angelo L. Vescovi, Francesco DiMeco, Alessandro Olivi, Charles G. Eberhart
Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma
Stem Cells Oct 2007; 25: 2524 - 2533 ; doi:10.1634/stemcells.2007-0166
Abstract

Chearwae W, Bright JJ
PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells
Br J Cancer. 2008 Nov 18. [Epub ahead of print]
  Abstract

Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG
Notch Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts
Histopathology. 2009 Nov;55(5):544-53
  Abstract |   Full Text |   Reprint

Gal H, Pandi G, Kanner AA, Ram Z, Lithwick-Yanai G, Amariglio N, Rechavi G, Givol D.
MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells
Biochem Biophys Res Commun. 2008 Aug 31; [Epub ahead of print]
 Abstract

Gallia GL, Tyler BM, Hann CL, Siu IM, Giranda VL, Vescovi AL, Brem H, Riggins GJ
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
Mol Cancer Ther. 2009 Feb;8(2):386-93. Epub 2009 Feb 10
  Abstract

Gangemi RM, Griffero F, Marubbi D, Perera M, Capra MC, Malatesta P, Ravetti GL, Zona GL, Daga A, Corte G
SOX2 Silencing in Glioblastoma Tumor Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity
Stem Cells. 2008 Oct 23; [Epub ahead of print]
  Abstract

Glantz M, Kesari S, Recht L, Fleischhack G, Van Horn A
Understanding the origins of gliomas and developing novel therapies: cerebrospinal fluid and subventricular zone interplay
Semin Oncol. 2009 Aug;36(4 Suppl 2):S17-24
  Abstract |   Full Text |   Reprint

Gürsel DB, Shin BJ, Burkhardt JK, Kesavabhotla K, Schlaff CD, Boockvar JA.
Glioblastoma Stem-Like Cells-Biology and Therapeutic Implications.
Cancers (Basel). 2011 Jun 10;3(2):2655-2666.
  Abstract |   Reprint |   Related articles

Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, Shi Q, Lathia JD, Macswords J, Lee J, McLendon RE, Rich JN.
Targeting a20 decreases glioma stem cell survival and tumor growth
PLoS Biol. 2010 Feb 23;8(2):e1000319
  Abstract |   Full Text |   Reprint

Huang Z, Cheng L, Guryanova Olga A, Wu Q and Bao S
Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting
Protein & Cell, 2010, Volume 1, Number 7, July 2010, Pages 638-655
  Abstract |   Reprint

Huszthy PC, Giroglou T, Tsinkalovsky O, Euskirchen P, Skaftnesmo KO, Bjerkvig R, von Laer D, Miletic H
Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy
PLoS One. 2009 Jul 20;4(7):e6314
  Abstract |   Full Text |   Reprint

Jiang H, Gomez-Manzano C, Aoki H, Alonso MM, Kondo S, McCormick F, Xu J, Kondo Y, Bekele BN, Colman H, Lang FF, Fueyo J
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death
J Natl Cancer Inst. 2007 Sep 19;99(18):1410-4. Epub 2007 Sep 11
  Abstract |   Full Text |   Reprint

Jurvansuu J, Zhao Y, Leung DS, Boulaire J, Yu YH, Ahmed S, Wang S
Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells
Cancer Res. 2008 Jun 15;68(12):4614-22
 Abstract | Full Text | Reprint

Kang MK, Kang SK
Pharmacologic blockade of chloride channel synergistically enhances apoptosis of chemotherapeutic drug-resistant cancer stem cells
Biochem Biophys Res Commun. 2008 Jun 30; [Epub ahead of print]
 Abstract

Kast RE, Belda-Iniesta C.
Suppressing Glioblastoma Stem Cell Function by Aldehyde Dehydrogenase Inhibition with Chloramphenicol or Disulfiram as a New Treatment Adjunct: An Hypothesis
Curr Stem Cell Res Ther. 2009 Dec 1;. [Epub ahead of print]
  Abstract

Kinoshita Y, Kamitani H, Mamun MH, Wasita B, Kazuki Y, Hiratsuka M, Oshimura M, Watanabe T
A gene delivery system with a human artificial chromosome vector based on migration of mesenchymal stem cells towards human glioblastoma HTB14 cells
Neurol Res. 2009 Jul 8;. [Epub ahead of print]
  Abstract

Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB, Rich JN.
Integrin alpha 6 regulates glioblastoma stem cells
Cell Stem Cell. 2010 May 7;6(5):421-32
  Abstract

Lu J, Zhuang Z, Song DK, Mehta GU, Ikejiri B, Mushlin H, Park DM, Lonser RR.
The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma
J Neurosurg. 2009 Dec 11;. [Epub ahead of print]
  Abstract

Ma HI, Chiou SH, Hueng DY, Tai LK, Huang PI, Kao CL, Chen YW, Sytwu HK.
Celecoxib and radioresistant glioblastoma-derived CD133(+) cells: improvement in radiotherapeutic effects.
J Neurosurg. 2010 Nov 5;. [Epub ahead of print]
  Abstract |   Related articles

Marian CO, Cho SK, McEllin BM, Maher EA, Hatanpaa KJ, Madden CJ, Mickey BE, Wright WE, Shay JW, Bachoo RM
The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth
Clin Cancer Res. 2010 Jan 1;16(1):154-63. Epub 2010 Jan 4
  Abstract

McCord AM, Jamal M, Williams ES, Camphausen K, Tofilon PJ
CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines
Clin Cancer Res. 2009 Aug 15;15(16):5145-53. Epub 2009 Aug 11
  Abstract

Park DM, Li J, Okamoto H, Akeju O, Kim SH, Lubensky I, Vortmeyer A, Dambrosia J, Weil RJ, Oldfield EH, Park JK, Zhuang Z
N-CoR pathway targeting induces glioblastoma derived cancer stem cell differentiation
Cell Cycle. 2007 Feb 15;6(4):467-70. Epub 2007 Feb 12
  Abstract |   Reprint

Piccirillo SG, Vescovi AL
Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells
Ernst Schering Found Symp Proc. 2006;(5):59-81
  Abstract

Rappa G, Mercapide J, Anzanello F, Prasmickaite L, Xi Y, Ju J, Fodstad O, Lorico A
Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets
Exp Cell Res. 2008 Mar 20; [Epub ahead of print]
 Abstract

Akihiro Otsuki, Suzanne Camilli, Ankita Patel, Shigeru Tanaka, E. Antonio Chiocca, and Yoshinaga Saeki
Characterizing an oncolytic virotherapy targeted towards brain tumor stem cells
AACR Meeting Abstracts, Apr 2006; 2006: 703
Abstract

Sara GM Piccirillo, Angelo L Vescovi PhD
Brain tumour stem cells: possibilities of new therapeutic strategies
Expert Opinion on Biological Therapy, August 2007, Vol. 7, No. 8, Pages 1129-1135
Abstract

S. G. M. Piccirillo, B. A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco and A. L. Vescovi
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Nature 444, 761-765 (7 December 2006). doi:10.1038/nature05349
Abstract | Reprint

Stupp R, Hegi ME
Targeting brain-tumor stem cells
Nat Biotechnol. 2007 Feb;25(2):193-4
  Abstract

Tunici P, Pellegatta S, Finocchiaro G.
The potential of stem cells for the treatment of brain tumors and globoid cell leukodystrophy
Cytotechnology. 2003 Mar;41(2-3):93-101
  Abstract

Wakimoto H, Kesari S, Farrell CJ, Curry WT Jr, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
Cancer Res. 2009 Apr 15;69(8):3472-81. Epub 2009 Apr 7
  Abstract

Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, Macswords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, Rich JN
Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth
Stem Cells. 2009 Aug 5;. [Epub ahead of print]
  Abstract

Xu Q, Liu G, Yuan X, Xu M, Wang H, Ji J, Konda B, Black KL, Yu JS.
Antigen-Specific T Cell Response from Dendritic Cell Vaccination Using Cancer Stem-like Cell-Associated Antigens
Stem Cells. 2009 Apr 23;. [Epub ahead of print]
  Abstract

Yuki K, Natsume A, Yokoyama H, Kondo Y, Ohno M, Kato T, Chansakul P, Ito M, Kim SU, Wakabayashi T.
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling
Cancer Lett. 2009 May 18;. [Epub ahead of print]
  Abstract

Zhao Y, Wang S
Human NT2 Neural Precursor-Derived Tumor-Infiltrating Cells as Delivery Vehicles for Treatment of Glioblastoma
Hum Gene Ther. 2010 Jan 29;. [Epub ahead of print]
  Abstract

Zhen Y, Zhao S, Li Q, Li Y, Kawamoto K.
Arsenic trioxide-mediated Notch pathway inhibition depletes the cancer stem-like cell population in gliomas
Cancer Lett. 2009 Dec 3;. [Epub ahead of print]
  Abstract

Zhu X, Bidlingmaier S, Hashizume R, James CD, Berger MS, Liu B
Identification of internalizing human single-chain antibodies targeting brain tumor sphere cells
Mol Cancer Ther. 2010 Jul;9(7):2131-41. Epub 2010 Jun 29
  Abstract

Ziegler DS, Wright RD, Kesari S, Lemieux ME, Tran MA, Jain M, Zawel L, Kung AL.
Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins
J Clin Invest. 2008 Aug 1; [Epub ahead of print]
 Abstract |  Full Text |  Reprint


Gliomas


Bexell D, Gunnarsson S, Siesjö P, Bengzon J, Darabi A
CD133+ and nestin+ tumor-initiating cells dominate in N29 and N32 experimental gliomas
Int J Cancer. 2009 Feb 3. [Epub ahead of print]
  Abstract

Bikeye SN, Colin C, Marie Y, Vampouille R, Ravassard P, Rousseau A, Boisselier B, Idbaih A, Calvo CF, Leuraud P, Lassalle M, El Hallani S, Delattre JY, Sanson M.
ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target
Cancer Cell Int. 2010 Jan 11;10:1
  Abstract |   Full Text |   Reprint

Blough MD, Beauchamp DC, Westgate MR, Kelly JJ, Cairncross JG
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma
J Neurooncol. 2010 Jul 1. [Epub ahead of print]
  Abstract

Burkhardt JK, Shin BJ, Boockvar JA.
Neural stem cells and glioma stem-like cells respond differently to chemotherapeutic drugs: selectivity at the cellular level.
Neurosurgery. 2011 Jun;68(6):N21-2. No abstract available.
  Abstract |   Related articles

Charles N, Ozawa T, Squatrito M, Bleau AM, Brennan CW, Hambardzumyan D, Holland EC
Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells
Cell Stem Cell. 2010 Feb 5;6(2):141-152
  Abstract

Eyler CE, Foo WC, Lafiura KM, McLendon RE, Hjelmeland AB, Rich JN.
Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition
Stem Cells. 2008 Sep 18; [Epub ahead of print]
  Abstract

Friedman GK, Langford CP, Coleman JM, Cassady KA, Parker JN, Markert JM, Yancey Gillespie G.
Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111
J Neurooncol. 2009 Jun 12;. [Epub ahead of print]
  Abstract

Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G, Raychaudhury A, Newton HB, Chiocca EA, Lawler S
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
Cancer Res. 2008 Nov 15;68(22):9125-30
  Abstract

Gong X, Schwartz PH, Linskey ME, Bota DA.
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
Neurology. 2011 Mar 29;76(13):1126-34. Epub 2011 Feb 23.
  Abstract |   Reprint |   Related articles

Gu C, Li S, Tokuyama T, Yokota N, Namba H.
Therapeutic effect of genetically engineered mesenchymal stem cells in rat experimental leptomeningeal glioma model
Cancer Lett. 2009 Nov 26;. [Epub ahead of print]
  Abstract

Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B, Abounader R.
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells
Cell Cycle. 2010 Mar 18;9(6). [Epub ahead of print]
  Abstract |   Reprint

Hyun KH, Yoon CH, Kim RK, Lim EJ, An S, Park MJ, Hyun JW, Suh Y, Kim MJ, Lee SJ.
Eckol suppresses maintenance of stemness and malignancies in glioma stem-like cells.
Toxicol Appl Pharmacol. 2011 Apr 14;. [Epub ahead of print]
  Abstract |   Related articles

Laks DR, Visnyei K, Kornblum HI
Brain tumor stem cells as therapeutic targets in models of glioma
Yonsei Med J. 2010 Sep;51(5):633-40. Published online 2010 July 15
  Abstract |   Full Text |   Reprint

Li Z, Wang H, Eyler CE, Rich JN
Turning cancer stem cells inside-out: an exploration of glioma stem cell signaling pathways
J Biol Chem. 2009 Mar 13;. [Epub ahead of print]
  Abstract |   Reprint

Neman J, Jandial R
Decreasing glioma recurrence through adjuvant cancer stem cell inhibition
Biologics. 2010 Jun 24;4:157-62
  Abstract |   Full Text |   Reprint

Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4822-7. Epub 2009 Mar 5
  Abstract

Shi L, Zhang J, Pan T, Zhou J, Gong W, Liu N, Fu Z, You Y.
MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation
Brain Res. 2009 Nov 27;. [Epub ahead of print]
  Abstract

Thon N, Damianoff K, Hegermann J, Grau S, Krebs B, Schnell O, Tonn JC, Goldbrunner R.
Presence of pluripotent CD133(+) cells correlates with malignancy of gliomas
Mol Cell Neurosci. 2008 Aug 7; [Epub ahead of print]
  Abstract

Toda M
Identification of antigen against brain tumor stem cell and application for treatment of glioma
Gan To Kagaku Ryoho. 2010 Jun;37(6):1016-8
  Abstract

Wang J, Wakeman TP, Lathia JD, Hjelmeland AB, Wang XF, White RR, Rich JN, Sullenger BA
Notch promotes radioresistance of glioma stem cells
Stem Cells. 2010 Jan;28(1):17-28. Epub 2009 Nov 17
  Abstract |   Full Text |   Reprint


Gliomas (High-Grade)


Aguado T, Carracedo A, Julien B, Velasco G, Milman G, Mechoulam R, Alvarez L, Guzmán M, Galve-Roperh I
Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis
J Biol Chem. 2007 Mar 2;282(9):6854-62. Epub 2007 Jan 2
 Abstract |  Full Text |  Reprint

Alonso MM, Jiang H, Gomez-Manzano C, Fueyo J.
Targeting brain tumor stem cells with oncolytic adenoviruses.
Methods Mol Biol. 2012;797:111-25.
  Abstract |   Related articles

Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE, Hjelmeland AB, Rich JN.
Targeting cancer stem cells through L1CAM suppresses glioma growth
Cancer Res. 2008 Aug 1;68(15):6043-8
 Abstract |  Reprint

Brown CE, Starr R, Martinez C, Aguilar B, D'Apuzzo M, Todorov I, Shih CC, Badie B, Hudecek M, Riddell SR, Jensen MC.
Recognition and Killing of Brain Tumor Stem-Like Initiating Cells by CD8+ Cytolytic T Cells
Cancer Res. 2009 Nov 10;. [Epub ahead of print]
  Abstract

Campos B, Wan F, Farhadi M, Ernst A, Zeppernick F, Tagscherer KE, Ahmadi R, Lohr J, Dictus C, Gdynia G, Combs SE, Goidts V, Helmke BM, Eckstein V, Roth W, Beckhove P, Lichter P, Unterberg A, Radlwimmer B, Herold-Mende C
Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
Clin Cancer Res. 2010 May 4;. [Epub ahead of print]
  Abstract

Chamberlain MC, Bota DA, Linskey ME, Schwartz PH.
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
Neurology. 2011 Nov 29;77(22):e135-6.
  Abstract |   Full text |   Related articles

Evers P, Lee PP, Demarco J, Agazaryan N, Sayre JW, Selch M, Pajonk F.
Irradiation of the Potential Cancer Stem Cell Niches in the Adult Brain Improves Progression-free Survival of Patients with Malignant Glioma
BMC Cancer. 2010 Jul 21;10(1):384. [Epub ahead of print]
  Abstract |   Reprint

Folkins C, Man S, Xu P, Shaked Y, Hicklin DJ, Kerbel RS
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors
Cancer Res. 2007 Apr 15;67(8):3560-4
 Abstract |  Reprint

A. G. Gilg, S. L. Tye, L. B. Tolliver, W. G. Wheeler, R. P. Visconti, J. D. Duncan, F. V. Kostova, L. N. Bolds, B. P. Toole, and B. L. Maria
Targeting Hyaluronan Interactions in Malignant Gliomas and Their Drug-Resistant Multipotent Progenitors
Clin. Cancer Res., March 15, 2008; 14(6): 1804 - 1813
 Abstract

Gong X, Schwartz PH, Linskey ME, Bota DA.
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
Neurology. 2011 Mar 29;76(13):1126-34. Epub 2011 Feb 23.
  Abstract |   Reprint |   Related articles

Hua W, Yao Y, Chu Y, Zhong P, Sheng X, Xiao B, Wu J, Yang B, Mao Y, Zhou L.
The CD133+ tumor stem-like cell-associated antigen may elicit highly intense immune responses against human malignant glioma.
J Neurooncol. 2011 Apr 11. [Epub ahead of print]
  Abstract |   Related articles

Jiang H, Fueyo J.
Eradication of brain tumor stem cells with an oncolytic adenovirus
Discov Med. 2010 Jul;10(50):24-8. Published on July 5, 2010
  Abstract |   Full Text

Kendall SE, Najbauer J, Johnston HF, Metz MZ, Li S, Bowers M, Garcia E, Kim SU, Barish ME, Aboody KS, Glackin CA
Neural Stem Cell Targeting of Glioma is Dependent on PI3K Signaling
Stem Cells. 2008 Mar 13; [Epub ahead of print]
Abstract |  Reprint | Supplemental Data

Laks DR, Masterman-Smith M, Visnyei K, Angenieux B, Orozco NM, Foran I, Yong WH, Vinters HV, Liau LM, Lazareff JA, Mischel PS, Cloughesy TF, Horvath S, Kornblum HI
Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
Stem Cells. 2009 Apr;27(4):980-7
  Abstract

Lee DH, Ahn Y, Kim SU, Wang KC, Cho BK, Phi JH, Park IH, Black PM, Carroll RS, Lee J, Kim SK
Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells
Clin Cancer Res. 2009 Aug 1;15(15):4925-34. Epub 2009 Jul 28
  Abstract

Oh MC, Lim DA
Novel treatment strategies for malignant gliomas using neural stem cells
Neurotherapeutics. 2009 Jul;6(3):458-64
  Abstract |   Full Text |   Reprint

Pellegatta S, Finocchiaro G
Dendritic cell vaccines for cancer stem cells
Methods Mol Biol. 2009;568:233-47.
  Abstract

Serena Pellegatta, Pietro Luigi Poliani, Daniela Corno, Francesca Menghi, Francesco Ghielmetti, Blanca Suarez-Merino, Valentina Caldera, Sara Nava, Maria Ravanini, Fabio Facchetti, Maria Grazia Bruzzone, and Gaetano Finocchiaro
Neurospheres Enriched in Cancer Stem–Like Cells Are Highly Effective in Eliciting a Dendritic Cell–Mediated Immune Response against Malignant Gliomas
Cancer Res 2006 Nov 1; 66: 10247-10252
Abstract | Reprint

Sauvageot CM, Weatherbee JL, Kesari S, Winters SE, Barnes J, Dellagatta J, Ramakrishna NR, Stiles CD, Kung AL, Kieran MW, Wen PY.
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells
Neuro Oncol. 2008 Aug 5; [Epub ahead of print]
 Abstract

Wu A, Wiesner S, Xiao J, Ericson K, Chen W, Hall WA, Low WC, Ohlfest JR
Expression of MHC I and NK ligands on human CD133+ glioma cells: possible targets of immunotherapy
J Neurooncol. 2007 Jun;83(2):121-31. Epub 2006 Nov 1. Erratum in: J Neurooncol. 2007 Jun;83(2):133
 Abstract |  Reprint


Medulloblastoma


Annabi B, Rojas-Sutterlin S, Laflamme C, Lachambre MP, Rolland Y, Sartelet H, Béliveau R
Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype
Mol Cancer Res. 2008 Jun;6(6):907-16
 Abstract |  Full Text |  Reprint

Elamin MH, Shinwari Z, Hendrayani SF, Al-Hindi H, Al-Shail E, Khafaga Y, Al-Kofide A, Aboussekhra A
Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells
Mol Carcinog. 2009 Dec 18;. [Epub ahead of print]
  Abstract

Fan X, Eberhart CG
Medulloblastoma stem cells
J Clin Oncol. 2008 Jun 10;26(17):2821-7
  Abstract

Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, Eberhart CG
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
Cancer Res. 2006 Aug 1;66(15):7445-52
  Abstract |   Full Text |   Reprint

Lu KH, Chen YW, Tsai PH, Tsai ML, Lee YY, Chiang CY, Kao CL, Chiou SH, Ku HH, Lin CH, Chen YJ
Evaluation of radiotherapy effect in resveratrol-treated medulloblastoma cancer stem-like cells
Childs Nerv Syst. 2009 Feb 19. [Epub ahead of print]
  Abstract

Rudin CM, Hann CL, Laterra J, Yauch RL, Callahan CA, Fu L, Holcomb T, Stinson J, Gould SE, Coleman B, LoRusso PM, Von Hoff DD, de Sauvage FJ, Low JA
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
N Engl J Med. 2009 Sep 17;361(12):1173-8. Epub 2009 Sep 2
  Abstract |   Full Text |   Reprint

Xing Fan, William Matsui, Leila Khaki, Jiong Chun, Yue-Ming Li, and Charles G. Eberhart
Notch pathway blockade targets medulloblastoma-initiating cancer stem cells
AACR Meeting Abstracts, Apr 2006; 2006: 1053
Abstract


Metastasis


M. Mimeault, R. Hauke, P. P. Mehta, S. K. Batra
Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers
J Cell Mol Med. Volume 11, CNO 5, Page 981-1011, Sep 2007, doi: 10.1111/j.1582-4934.2007.00088.x
 Abstract |  Full Text |  Reprint


Neuroblastoma


Tsuchida R, Das B, Yeger H, Koren G, Shibuya M, Thorner PS, Baruchel S, Malkin D.
Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling
Oncogene. 2008 Jun 26;27(28):3923-34. Epub 2008 Mar 10
 Abstract


Pediatric Patients


Calvin Li S, Han YP, Dethlefs BA, Günter Loudon W
Therapeutic Window of Stem Cell Potential for Targeting Pediatric Malignant Brain Tumors: An Opportunity for Stem Cell Therapy
Stem Cell Rev Rep. 2009 Apr 23;. [Epub ahead of print]
  Abstract |   Full Text |   Reprint

Thirant C, Bessette B, Varlet P, Puget S, Cadusseau J, Dos Reis Tavares S, Studler JM, Silvestre DC, Susini A, Villa C, Miquel C, Bogeas A, Surena AL, Dias-Morais A, Léonard N, Pflumio F, Biéche I, Boussin FD, Sainte-Rose C, Grill J, Daumas-Duport C, Chneiweiss H, Junier MP.
Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.
PLoS One. 2011 Jan 28;6(1):e16375.
  Abstract |   Reprint |   Related articles


Targeted CSC Therapies


Evers P, Lee PP, DeMarco J, Agazaryan N, Sayre JW, Selch M, Pajonk F.
Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma.
BMC Cancer. 2010 Jul 21;10:384
  Abstract |   Reprint |   Related articles

Vlashi E, Pajonk F.
Targeted cancer stem cell therapies start with proper identification of the target.
Mol Cancer Res. 2010 Feb;8(2):291; author reply 291. Epub 2010 Feb 9.
  Abstract |   Reprint |   Related articles

Vlashi E, McBride WH, Pajonk F.
Radiation responses of cancer stem cells.
J Cell Biochem. 2009 Oct 1;108(2):339-42.
  Abstract |   Reprint |   Related articles

Vlashi E, Kim K, Lagadec C, Donna LD, McDonald JT, Eghbali M, Sayre JW, Stefani E, McBride W, Pajonk F.
In vivo imaging, tracking, and targeting of cancer stem cells.
J Natl Cancer Inst. 2009 Mar 4;101(5):350-9. Epub 2009 Feb 24. Erratum in: J Natl Cancer Inst. 2009 Jun 3;101(11):833.
  Abstract |   Reprint |   Erratum |   Related articles

Woodward WA, Bristow RG, Clarke MF, Coppes RP, Cristofanilli M, Duda DG, Fike JR, Hambardzumyan D, Hill RP, Jordan CT, Milas L, Pajonk F, Curran WJ, Dicker AP, Chen Y.
Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials.
Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1580-91. Epub 2009 Jun 17.
  Abstract |   Related articles


Telomere Maintenance


Castelo-Branco P, Zhang C, Lipman T, Fujitani M, Hansford L, Clarke I, Harley CB, Tressler R, Malkin D, Walker E, Kaplan DR, Dirks P, Tabori U.
Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition.
Clin Cancer Res. 2011 Jan 1;17(1):111-21.
  Abstract |   Reprint |   News    News |   Related articles

Hjelmeland AB, Rich JN.
Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It!
Clin Cancer Res. 2011 Jan 1;17(1):3-5.
  Abstract |   Related articles


This website is certified by Health On the Net Foundation. Click to verify. HOME ARCHIVES OF NEURO-ONCOLOGY CURRENT NEURO-ONCOLOGY NEWS CLINICAL NEURO-ONCOLOGY LIBRARY
DATABASE: Classification | Diagnosis | Epidemiology | Etiology & Pathogenesis | Integrative Medicine | Overall Management | Prognosis | Psychosocial Aspects | Stem Cells | Treatment
SERVICES
: About BrainLife | Children's Corner | E-mail Alerts | Journals | Links |
Motto, Dedication, etc. | Patients & Caregivers | Privacy Policy | Search | SiteMap bottom
This site complies with the HONcode standard for trustworthy health information: verify here