BRAINLIFE Brain Tumor Medical Database

Carboplatin

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Astrocytomas


E. Lopez Aguilar, S. Delgado-Huerta, A. C. Sepulveda-Vildosola, V. Wanzke-Del-angel, H. Rodriguez-Jimenez
Neoadjuvant chemotherapy with temozolamide plus ifosfamide, carboplatin and etoposide in pediatric patients with high grade astrocytomas. Phase II study
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 463

Chen B, Ahmed T, Mannancheril A, Gruber M, Benzil DL
Safety and efficacy of high-dose chemotherapy with autologous stem cell transplantation for patients with malignant astrocytomas
Cancer. 2004 May 15;100(10):2201-7


Brain Tumors


Fiorillo A, Maggi G, Greco N, Migliorati R, D'Amico A, De Caro MD, Sabbatino MS, Buffardi F
Second-line chemotherapy with the association of liposomal daunorubicin, carboplatin and etoposide in children with recurrent malignant brain tumors
J Neurooncol. 2004 Jan;66(1-2):179-85

R.J. Strege, Y.J. Liu, A. Kiely, R.M. Johnson, E.M. Gillis, P. Storm, B.S. Carson, G.I. Jallo, M. Guarnieri
Toxicity and Cerebrospinal Fluid Levels of Carboplatin Chronically Infused into the Brainstem of a Primate
Journal of Neuro-Oncology,
67 (3): 327-334, May 2004. (Abstract+)


Embryonal Tumors


Fidani P, De Ioris MA, Serra A, De Sio L, Ilari I, Cozza R, Boldrini R, Milano GM, Garrè ML, Donfrancesco A
A multimodal strategy based on surgery, radiotherapy, ICE regimen and high dose chemotherapy in atypical teratoid/rhabdoid tumours: a single institution experience
J Neurooncol. 2009 Apr;92(2):177-83. Epub 2008 Nov 29
  Abstract


Germ Cell Tumors


Kellie SJ, Boyce H, Dunkel IJ, Diez B, Rosenblum M, Brualdi L, Finlay JL
Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol
J Clin Oncol. 2004 Mar 1;22(5):846-53


Glioblastoma


Aoki T, Takahashi JA, Ueba T, Oya N, Hiraoka M, Matsui K, Fukui T, Nakashima Y, Ishikawa M, Hashimoto N.
Phase II study of nimustine, carboplatin, vincristine, and interferon-beta with radiotherapy for glioblastoma multiforme: experience of the Kyoto Neuro-Oncology Group.
J Neurosurg. 2006 Sep;105(3):385-91.
Abstract


Tomokazu Aoki, Tetsuya Ueba, Jun Takahashi, Natstuo Ooya, Masahiro Hiraoka, Masatsune Ishikwa, and Nobuo Hashimoto
Vincristine, ACNU, Carboplatin and Interferon Beta with Radiation (VAC-FERON-R) for Newly Diagnosed Glioblastoma Multiforme
15th International Conference on Brain Tumor Research and Therapy. Sorrento, Italy. May 24–27, 2003. Abstract No. 3
Neuro-Oncology, Volume 5, CNO 4, October 2003 

Levin VA, Maor MH, Thall PF, Yung WK, Bruner J, Sawaya R, Kyritsis AP, Leeds N, Woo S, Rodriguez L, et al
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme
Int J Radiat Oncol Biol Phys. 1995 Sep 30;33(2):357-64 

J. M. Simon, G. Noel, K. Hoang-Xuan, A. F. Carpentier, K. Mokhtari, S. Racadot, F. Baillet, J. J. Mazeron
Radiotherapy and concomitant weekly carboplatin and daily etoposide for patients with inoperable biopsy proven glioblastoma multiforme
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1544

Recurrent Tumors


Aoki T, Mizutani T, Nojima K, Takagi T, Okumura R, Yuba Y, Ueba T, Takahashi JA, Miyatake SI, Nozaki K, Taki W, Matsutani M
Phase II study of ifosfamide, carboplatin, and etoposide in patients with a first recurrence of glioblastoma multiforme
J Neurosurg. 2009 Jun 19. [Epub ahead of print]
  Abstract

de Groot JF, Gilbert MR, Aldape K, Hess KR, Hanna TA, Ictech S, Groves MD, Conrad C, Colman H, Puduvalli VK, Levin V, Yung WK
Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma
J Neurooncol. 2008 Jun 26; [Epub ahead of print]
 Abstract

Francesconi AB, Dupre S, Matos M, Martin D, Hughes BG, Wyld DK, Lickliter JD
Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme
J Clin Neurosci. 2010 Jun 9;. [Epub ahead of print]
  Abstract

Jo Glass, Gruber Michael , Anit Nirenberg
Phase I/II Study of Carboplatin and Thalidomide in Recurrent Glioblastoma Multiforme
ASCO Proceedings, 1999 Annual Meeting, Abstract 


Reardon DA, Desjardins A, Peters KB, Gururangan S, Sampson JH, McLendon RE, Herndon JE 2nd, Bulusu A, Threatt S, Friedman AH, Vredenburgh JJ, Friedman HS.
Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab
naïve, recurrent glioblastoma.
J Neurooncol. 2011 Oct 11;. [Epub ahead of print]
  Abstract |   Related articles

White E, Bienemann A, Taylor H, Hopkins K, Cameron A, Gill S.
A phase I trial of carboplatin administered by convection-enhanced delivery to patients with recurrent/progressive glioblastoma multiforme.
Contemp Clin Trials. 2011 Nov 12;. [Epub ahead of print]
  Abstract |   Related articles


Gliofibroma


C. R. Suarez, S. J. Bertolone
Carboplatinum (CBDCA), vincristine (V) therapy for CNS gliofibroma
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 461


Gliomas


Giovanna Cavallo, Luciano Scopece, Enrico Franceschi, Roberta Degli Esposti, Elisabetta Setola, Cesare Calandri, Samir Darwish, Lucio Crino
Phase II trial with carboplatin (CBCDA) and etoposide (VP-16) in recurrent high grade gliomas
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No. 307


Cloughesy TF, Black KL, Gobin YP, Farahani K, Nelson G, Villablanca P, Kabbinavar F, Vineula F, Wortel CH
Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas
Neurosurgery 1999 Feb;44(2):270-8

Elpis Mantadakis, Maria Raissaki, Vassiliki Danilatou, Alexander Kambourakis, Eftichia Stiakaki and Maria Kalmanti
Remission of a chiasmatic glioma in a non-NF1 patient after brief chemotherapy with vincristine and carboplatin: case report and literature review
J Neurooncol. 2004 Mar-Apr;67(1-2):95-100. (Abstract+)

Mastronardi L, Puzzilli F, Couldwell WT, Farah JO, Lunardi P.
Tamoxifen and carboplatin combinational treatment of high-grade gliomas. Results of a clinical trial on newly diagnosed patients
J Neurooncol 1998 May;38(1):59-68 

Prados MD, Schold SC JR SC, Fine HA, Jaeckle K, Hochberg F, Mechtler L, Fetell MR, Phuphanich S, Feun L, Janus TJ, Ford K, Graney W
A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma
Neuro-oncol. 2003 Apr;5(2):96-103

P. Tang, G. Roldan, P.M.A Brasher, D. Fulton, W. Roa, A. Murtha, J.G. Cairncross and P.A. Forsyth
A phase II study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma
J Neurooncol. 2006 May 19; [Epub ahead of print]; DOI: 10.1007/s11060-005-9104-y
Abstract

Yung WK, Mechtler L, Gleason MJ
Intravenous carboplatin for recurrent malignant glioma: a phase II study
J Clin Oncol 1991 May;9(5):860-4



Gliomas (High-Grade)


Dufour C, Grill J, Lellouch-Tubiana A, Puget S, Chastagner P, Frappaz D, Doz F, Pichon F, Plantaz D, Gentet JC, Raquin MA, Kalifa C.
High-grade glioma in children under 5 years of age: A chemotherapy only approach with the BBSFOP protocol.
Eur J Cancer. 2006 Sep 6; [Epub ahead of print]
Abstract


Recurrent Tumors


Murray LJ, Bridgewater CH, Levy D.
Carboplatin Chemotherapy in Patients with Recurrent High-grade Glioma.
Clin Oncol (R Coll Radiol). 2010 Oct 15;. [Epub ahead of print]
  Abstract |   Related articles

Schäfer N, Tichy J, Thanendrarajan S, Kim Y, Stuplich M, Mack F, Rieger J, Simon M, Scheffler B, Boström J, Steinbach JP, Herrlinger U, Glas M.
Ifosfamide, Carboplatin and Etoposide in Recurrent Malignant Glioma.
Oncology. 2011 Jul 27;80(5-6):330-332. [Epub ahead of print]
  Abstract |   Related articles


Gliomas (Low-Grade)


Lafay-Cousin L, Holm S, Qaddoumi I, Nicolin G, Bartels U, Tabori U, Huang A, Bouffet E
Weekly vinblastine in pediatric low-grade glioma patients with carboplatin allergic reaction
Cancer. 2005 Apr 28; [Epub ahead of print]

Ronghe M, Hargrave D, Bartels U, Tabori U, Vaidya S, Chandler C, Kulkarni A, Bouffet E.
Vincristine and carboplatin chemotherapy for unresectable and/or recurrent low-grade astrocytoma of the brainstem
Pediatr Blood Cancer. 2010 May 26;. [Epub ahead of print]
  Abstract

Sridharan Gururangan, Christina M. Cavazos, David Ashley, James E. Herndon, II, Carol S. Bruggers, Albert Moghrabi, Deborah L. Scarcella, Melody Watral, Sandra Tourt-Uhlig, David Reardon, Henry S. Friedman
Phase II Study of Carboplatin in Children With Progressive Low-Grade Gliomas
. (Abstract+)


Medulloblastoma


F. Spreafico, M. Massimino, L. Gandola, S. Siena, G. Cefalo, E. Mazza, P. Versari, G. Landonio, P. Pedrazzoli, F. Fossati-Bellani
Survival results in adults treated for medulloblastoma
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 479


Metastatic Tumors


D. Y. Kim, K. W. Lee, T. Yun, J. H. Kim, D. W. Kim, S. A. Im, T. Y. Kim, D. S. Heo, Y. J. Bang, N. K. Kim
Efficacy of platinum-based chemotherapy after cranial irradiation in patients with brain metastasis from non-small cell lung cancer
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1575

Jane W. Marsh, Maryann Donovan, Dennis R. Burholt, Lisa D. George and Paul L. Kornblith
Metastatic lung disease to the central nervous system: in vitro response to chemotherapeutic agents
Journal of Neuro-Oncology 66: 81–90, January 2004

Robert Morgan Jr., Timothy Synold, Adam Mamelak, Kim Margolin, Al-Kadhimi Zaid, Przemyslaw Twardowski, Lucille Leong, Dean Lim, Sandeep Reddy, Isan Chen, Warren Chow, Stephen Shibata, George Somlo, Yun Yen, Paul Frankel, James H Doroshow
Phase I trial of tamoxifen (Tam), carboplatin (C), and topotecan (T) in recurrent or metastatic brain tumors
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No. 2102



Oligod. T. & Mixed Gliomas


U. Basso, F. Vastola, L. M. Pasetto, A. Scola, M. Ermani, M. Cacciacarne, F. Sala, A. Talacchi, M. K. Paris, A. A. Brandes
Carboplatin and VM-26 as third-line chemotherapy in patients with oligodendroglioma refractory to PCV and temozolomide
3
9th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 433

A. A. Brandes, U. Basso, F. Vastola, A. Tosoni, L. M. Pasetto, A. Jirillo, S. Lonardi, M. K. Paris, H. Koussis, S. Monfardini and M. Ermani
Carboplatin and teniposide as third-line chemotherapy in patients with recurrent oligodendroglioma or oligoastrocytoma: a phase II study
Annals of Oncology 14:1727-1731, December 2003

L. Scopece, G. Cavallo, E. Palmerini, E. Franceschi, A. Paioli, F. Spagnolli, S. Rimondini, R. Conforti, R. Degli Esposti, L. Crino
Carboplatin and etoposide (CE) chemotherapy in patients with recurrent or progressive oligodendroglial tumors
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1562

Soffietti R, Nobile M, Ruda R, Borgognone M, Costanza A, Laguzzi E, Mutani R
Second-line treatment with carboplatin for recurrent or progressive oligodendroglial tumors after PCV (procarbazine, lomustine, and vincristine) chemotherapy: a phase II study
Cancer. 2004 Feb 15;100(4):807-13


Pediatric Patients


Fouladi M, Gururangan S, Moghrabi A, Phillips P, Gronewold L, Wallace D, Sanford RA, Gajjar A, Kun LE, Heideman R
Carboplatin-based primary chemotherapy for infants and young children with CNS tumors
Cancer. 2009 Jul 15;115(14):3243-53
  Abstract

López-Aguilar E, Sepúlveda-Vildósola AC, Betanzos-Cabrera Y, Rocha-Moreno YG, Gascón-Lastiri G, Rivera-Márquez H, Wanzke-Del-Angel V, Cerecedo-Díaz F, Cruz-Yañez Hde L.
Phase II Study of Metronomic Chemotherapy with Thalidomide, Carboplatin-Vincristine-Fluvastatin in the Treatment of Brain Stem Tumors in Children
Arch Med Res. 2008 Oct;39(7):655-62; Epub 2008 Aug 17
 Abstract

K. Warren, R. Jakacki, B. Widemann, A. Aikin, M. Libucha, R. Packer, G. Vezina, G. Reaman, D. Shaw, M. Krailo, C. Osborne, J. Cehelsky, D. Caldwell, J. Stanwood, S. M. Steinberg and F. M. Balis 
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children’s Oncology Group
Cancer Chemotherapy and Pharmacology, Vol. 58, No. 3, Sept 2006; DOI: 10.1007/s00280-005-0172-7; Pub. Online: 12 January 2006
Abstract

 

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