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Treatment > Chemotherapy-Enhancing Agents


Glioblastoma


Durmaz R, Deliorman S, Uyar R, Isiksoy S, Erol K, Tel E
The effects of anticancer drugs in combination with nimodipine and verapamil on cultured cells of glioblastoma multiforme
Clin Neurol Neurosurg. 1999 Dec;101(4):238-44
 

Huang CX, Chen B, Zhang YF
Growth inhibition of epidermal growth factor-stimulated human glioblastoma cells by nicardipine in vitro
Hunan Yi Ke Da Xue Xue Bao. 2001 Jun 28;26(3):211-4 


Gliomas


Aas AT, Brun A, Pero RW, Salford LG.
Chlorpromazine in combination with nitrosourea inhibits experimental glioma growth.
Br J Neurosurg 1994;8(2):187-92  

Bowles AP Jr, Pantazis CG, Wansley W
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study
J Neurosurg 1990 Aug;73(2):248-53 

Cloughesy TF, Black KL, Gobin YP, Farahani K, Nelson G, Villablanca P, Kabbinavar F, Vineula F, Wortel CH
Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas
Neurosurgery 1999 Feb;44(2):270-8 

P. Z. New, S. Grossman, T. Mikkelsen, T. Batchelor, S. Phuphanich, K. Carson, J. Fisher, M. Craig, P. Cagnoni
Evaluation of safety and tolerance of escalating doses of RSR13 administered with a fixed dose of BCNU every six weeks in patients with recurrent malignant glioma: Results of the phase I NABTT 9806 clinical trial
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1533 

Pamela Z New, Stuart A Grossman, Tracy Batchelor, Fred Hochberg, Surasak Phuphanich, Kathryn Carson, Regina Priett
Evaluation of safety and tolerance of escalating doses of RSR13 administered with a fixed dose of BCNU every six weeks in patients with recurrent malignant glioma: preliminary data of NABTT 9806 phase I/II clinical trial
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No.
2098  

Prados MD, Schold SC JR SC, Fine HA, Jaeckle K, Hochberg F, Mechtler L, Fetell MR, Phuphanich S, Feun L, Janus TJ, Ford K, Graney W
A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma
Neuro-oncol. 2003 Apr;5(2):96-103  

Soma MR, Pagliarini P, Butti G, Paoletti R, Paoletti P, Fumagalli R
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells

Cancer Res 1992 Aug 15;52(16):4348-55 



Metastatic Tumors


Belpomme D, Gauthier S, Pujade-Lauraine E, Facchini T, Goudier MJ, Krakowski I, Netter-Pinon G, Frenay M, Gousset C, Marie FN, Benmiloud M, Sturtz F
Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma
Ann Oncol 2000 Nov;11(11):1471-6 


Non-Nervous System Tumors


Beiderbeck-Noll AB, Sturkenboom MC, van der Linden PD, Herings RM, Hofman A, Coebergh JW, Leufkens HG, Stricker BH
Verapamil is associated with an increased risk of cancer in the elderly: the Rotterdam study
Eur J Cancer 2003 Jan;39(1):98-105 

Figueredo A, Arnold A, Goodyear M, Findlay B, Neville A, Normandeau R, Jones A
Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer. A phase I/II study
Cancer 1990 May 1;65(9):1895-902 

Loo TW, Clarke DM
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism
J Natl Cancer Inst 2000 Jun 7;92(11):898-902
 

 

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