Treatment > Differentiation Agents


Butyrates

Engelhard HH, Homer RJ, Duncan HA, Rozental J
Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells
J Neurooncol 1998 Apr;37(2):97-108 (Cell Culture Study, Abstract)

Pili R, Kruszewski MP, Hager BW, Lantz J, Carducci MA
Combination of phenylbutyrate and 13-cis retinoic acid inhibits prostate tumor growth and angiogenesis
Cancer Res 2001 Feb 15;61(4):1477-85 (Cell Culture Study, Abstract & PDF Full Text)

Zheng X, Chang RL, Cui XX, Kelly KA, Shih WJ, Lin Y, Strair R, Suh J, Han ZT, Rabson A, Conney AH
Synergistic effects of clinically achievable concentrations of 12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in HL-60 cells
Oncol Res 2000;12(9-10):419-27 (Cell Culture Study, Abstract)


Datura Stramonium

Sasaki T, Yamazaki K, Yamori T, Endo T
Inhibition of proliferation and induction of differentiation of glioma cells with Datura stramonium agglutinin

Br J Cancer 2002 Oct 7;87(8):918-23
(Cell Culture Study, Abstract)


Valproic Acid

Blaheta RA, Cinatl J Jr
Anti-tumor mechanisms of valproate: a novel role for an old drug
Med Res Rev 2002 Sep;22(5):492-511 (Review Article, Abstract)

Driever PH, Knupfer MM, Cinatl J, Wolff JE
Valproic acid for the treatment of pediatric malignant glioma
Klin Padiatr 1999 Jul-Aug;211(4):323-8 (Review Article, Abstract)

Rincon Castro LM, Gallant M, Niles LP
Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells
J Neurochem. 2005 Dec;95(5):1227-36. (Laboratory Investigation, Abstract)

 

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