BRAINLIFE Brain Tumor Medical Database

Drug Delivery

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Brain Tumors


Frank RT, Edmiston M, Kendall SE, Najbauer J, Cheung CW, Kassa T, Metz MZ, Kim SU, Glackin CA, Wu AM, Yazaki PJ, Aboody KS
Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies
PLoS One. 2009 Dec 15;4(12):e8314
  Abstract |   Full Text |   Reprint

Arifin DY, Lee KY, Wang CH.
Chemotherapeutic drug transport to brain tumor
J Control Release. 2009 Apr 17;. [Epub ahead of print]
  Abstract

Hashizume R, Ozawa T, Gryaznov SM, Bollen AW, Lamborn KR, Frey Ii WH, Deen DF
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163
Neuro Oncol. 2008 Feb 20; [Epub ahead of print]
 Abstract

Hodozuka A, Hayashi Y, Annei R, Hiroshima S, Saito M, Orimoto R, Sato M, Tanaka T
Intrathecal infusion of the antineoplastic agents for meningeal dissemination
Gan To Kagaku Ryoho. 2008 Jun;35(6):900-5
 Abstract

Invernici G, Cristini S, Alessandri G, Navone SE, Canzi L, Tavian D, Redaelli C, Acerbi F, Parati EA.
Nanotechnology advances in brain tumors: the state of the art.
Recent Pat Anticancer Drug Discov. 2011 Jan 1;6(1):58-69.
  Abstract |   Related articles

Kim SU
Neural Stem Cell-based Gene Therapy for Brain Tumors
Stem Cell Rev. 2010 Jun 3;. [Epub ahead of print]
  Abstract

Ningaraj NS, Sankpal UT, Khaitan D, Meister EA, Vats T
Activation of K(ATP) channels increases anticancer drug delivery to brain tumors and survival
Eur J Pharmacol. 2008 Nov 9;. [Epub ahead of print]
  Abstract

Pardridge WM. 
shRNA and siRNA delivery to the brain.
Adv Drug Deliv Rev. 2007 Mar 16; [Epub ahead of print]
PMID: 17434235 [PubMed - as supplied by publisher]

Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K. 
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound.
Int J Cancer. 2007 Apr 16; [Epub ahead of print]
PMID: 17437269 [PubMed - as supplied by publisher]

Sawyer AJ, Piepmeier JM, Saltzman WM.
New methods for direct delivery of chemotherapy for treating brain tumors.
Yale J Biol Med. 2006 Dec;79(3-4):141-52. Published online 2007 Oct.
Full Text | Reprint

Wohlfart S, Gelperina S, Kreuter J.
Transport of drugs across the blood-brain barrier by nanoparticles.
J Control Release. 2011 Aug 18. [Epub ahead of print]
  Abstract |   Related articles


Glioblastoma


Jain KK.
Use of nanoparticles for drug delivery in glioblastoma multiforme.
Expert Rev Neurother. 2007 Apr;7(4):363-72.
PMID: 17425491 [PubMed - in process]

Kreuter J, Gelperina S
Use of nanoparticles for cerebral cancer
Tumori. 2008 Mar-Apr;94(2):271-7
 Abstract

Liu HL, Hua MY, Chen PY, Chu PC, Pan CH, Yang HW, Huang CY, Wang JJ, Yen TC, Wei KC.
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment.
Radiology. 2010 May;255(2):415-25.
  Abstract |   Reprint |   Related articles

Mina Nikanjam, Eleanor A. Blakely, Kathleen A. Bjornstad, Xiao Shu, Thomas F. Budinger, Trudy M. Forte
Synthetic nano-low density lipoprotein as targeted drug delivery vehicle for glioblastoma multiforme
International Journal of Pharmaceutics, Article in Press, Available online 31 July 2006, DOI: 10.1016/j.ijpharm.2006.07.046 
Abstract | Reprint | News

Shahar T, Ram Z, Kanner AA.
Convection-enhanced delivery catheter placements for high-grade gliomas: complications and pitfalls.
J Neurooncol. 2011 Nov 4;. [Epub ahead of print]
  Abstract |   Related articles

Sugiyama SI, Yamashita Y, Kikuchi T, Sonoda Y, Kumabe T, Tominaga T.
Enhanced antitumor effect of combinedmodality treatment using convectionenhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts
Neurol Res. 2008 Jul 30; [Epub ahead of print]
 Abstract


Gliomas


Akbar U, Jones T, Winestone J, Michael M, Shukla A, Sun Y, Duntsch C
Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection
J Neurooncol. 2009 Apr 1. [Epub ahead of print]
  Abstract

Benny O, Menon LG, Ariel G, Goren E, Kim SK, Stewman C, Black PM, Carroll RS, Machluf M
Local delivery of poly lactic-co-glycolic acid microspheres containing imatinib mesylate inhibits intracranial xenograft glioma growth
Clin Cancer Res. 2009 Feb 15;15(4):1222-31
  Abstract

Brem S, Tyler B, Li K, Pradilla G, Legnani F, Caplan J, Brem H
Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model
Cancer Chemother Pharmacol. 2007 Oct;60(5):643-50. Epub 2007 Jan 26.
  Abstract

Burkhardt JK, Riina HA, Shin BJ, Moliterno JA, Hofstetter CP, Boockvar JA.
Intra-arterial chemotherapy for malignant gliomas: a critical analysis.
Interv Neuroradiol. 2011 Sep;17(3):286-95. Epub 2011 Oct 17.
  Abstract |   Related articles

Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K.
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide
Mol Cancer Ther. 2008 Nov 1;7(11):3575-85
  Abstract

Yot Navalitloha, Erica S. Schwartz, Elizabeth N. Groothuis, Cathleen V. Allen, Robert M. Levy and Dennis R. Groothuis
Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors
Neuro-oncol 2006 Jul 1; 8(3):227-233; Epub 2006 Jun 14
Abstract

Roger M, Clavreul A, Venier-Julienne MC, Passirani C, Sindji L, Schiller P, Montero-Menei C, Menei P
Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors
Biomaterials. 2010 Aug 3;. [Epub ahead of print]
  Abstract

Sampson JH, Raghavan R, Brady ML, Provenzale JM, Herndon JE 2nd, Croteau D, Friedman AH, Reardon DA, Coleman RE, Wong T, Bigner DD, Pastan I, Rodriguez-Ponce MI, Tanner P, Puri R, Pedain C. 
Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions.
Neuro-oncol. 2007 Apr 13; [Epub ahead of print]

Sarin H
Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors
J Transl Med. 2009 Sep 1;7(1):77. [Epub ahead of print]
  Abstract |   Reprint


Sarin H, Kanevsky AS, Wu H, Brimacombe KR, Fung SH, Sousa AA, Auh S, Wilson CM, Sharma K, Aronova MA, Leapman RD, Griffiths GL, Hall MD
Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
J Transl Med. 2008 Dec 18;6(1):80. [Epub ahead of print]
  Abstract |   Reprint

Yang B, Wu X, Mao Y, Bao W, Gao L, Zhou P, Xie R, Zhou L, Zhu J
Dual-targeted antitumor effects against brainstem glioma by intravenous delivery of tumor necrosis factor-related, apoptosis-inducing, ligand-engineered human mesenchymal stem cells
Neurosurgery. 2009 Sep;65(3):610-24
  Abstract


Gliomas (High-Grade)


Frosina G.
Stem Cell-Mediated Delivery of Therapies in the Treatment of Glioma.
Mini Rev Med Chem. 2011 May 16;. [Epub ahead of print]
  Abstract |   Related articles

Germano IM, Emdad L, Qadeer ZA, Binello E, Uzzaman M.
Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas
Cancer Gene Ther. 2010 Jun 4;. [Epub ahead of print]
  Abstract

Ryuta Saito, Michal T. Krauze, Charles O. Noble, Daryl C. Drummond, Dmitri B. Kirpotin, Mitchel S. Berger, John W. Park and Krystof S. Bankiewicz
Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model
Neuro-oncol 2006 Jul 1; 8(3):205-214; Epub 2006 May 24
Abstract

Shingaki T, Inoue D, Furubayashi T, Sakane T, Katsumi H, Yamamoto A, Yamashita S
Transnasal Delivery of Methotrexate to Brain Tumors in Rats: A New Strategy for Brain Tumor Chemotherapy
Mol Pharm. 2010 Aug 9;. [Epub ahead of print]
  Abstract

 

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