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Astrocytic
Tumors
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Facoetti A, Nan R, Zelini P,
Morbini P, Benericetti E, Ceroni M, Campoli M, Ferrone S
Human leukocyte
antigen and antigen processing machinery component defects in
astrocytic tumors
Clin
Cancer Res. 2005 Dec 1;11(23):8304-11
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Brain
Tumors
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David M. Ashley, Brenda Faiola, Smita Nair, Laura P. Hale,
Darell D. Bigner, and Eli Gilboa
Bone Marrow-generated Dendritic Cells Pulsed with Tumor Extracts or Tumor
RNA Induce Antitumor Immunity against Central Nervous System Tumors
J. Exp. Med., Volume 186, Number 7, October 6, 1997 1177-1182
Abstract
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Reprint
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Denise A. Caruso, Lisa M. Orme, Alana M. Neale, Fiona J. Radcliff, Gerlinda
M. Amor, Wirginia Maixner, Peter Downie, Timothy E. Hassall, Mimi L.K. Tang,
David M. Ashley
Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed
with tumor RNA in children and young adults with brain cancer
Neuro-Oncology, Vol. 6, No. 3, July
2004, 236 -- 246. (Abstract+)
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German
G. Gomez, Susana B. Read, Lazaro E. Gerschenson, Daniela Santoli, Adam
Zweifach, Carol A. Kruse
Interactions of the allogeneic effector leukemic
T cell line, TALL-104, with human malignant brain tumors
Neuro-Oncology, April 2004, Volume 6, Number 2, Pages 83 – 95
(Abstract+)
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Peter E. Fecci, Duane A. Mitchell,
Gary E. Archer, Michael A. Morse, H. Kim Lyerly,
Darell D. Bigner and John H. Sampson
The History, Evolution, and Clinical use of Dendritic Cell-Based
Immunization Strategies in the Therapy of Brain Tumors
J Neurooncol. 2003
Aug-Sep;64(1-2):161-76. Epub 2004 Oct 31
Abstract
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Reprint
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Maciej S. Lesniak,
Patrick Gabikian,
Betty M. Tyler,
Drew M. Pardoll,
Henry Brem
Dexamethasone Mediated Inhibition of Local IL-2 Immunotherapy is Dose Dependent
in Experimental Brain Tumors
J Neurooncol, 70 (1): 23-28, Oct 2004. (Abstract+)
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Christoph
Mamot, Daryl C Drummond, Keelung Hong, Dmitri B Kirpotin, James D Marks,
John Nguyen, Krys Bankiewicz, Mitchel Berger, John W Park
Development
of immunoliposomes for brain tumor treatment
38th
ASCO Annual Meeting. Orlando, FL. May 18-21, 2002.
Abstract No.
287
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Prins RM, Shu CJ, Radu CG, Vo DD, Khan-Farooqi
H, Soto H, Yang MY, Lin MS, Shelly S, Witte ON, Ribas A, Liau LM
Anti-tumor activity and trafficking of self, tumor-specific T cells
against tumors located in the brain
Cancer Immunol Immunother. 2008 Feb 6; [Epub ahead of print]
Abstract
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Prins, Robert M. Ph.D.; Bruhn, Kevin W. Ph.D.;
Craft, Noah M.D., Ph.D.; Lin, Jia Wei M.D.; Kim, Choong-Hyun M.D., Ph.D.;
Odesa, Sylvia K. B.S.; Miller, Jeff F. Ph.D.; Liau, Linda M. M.D., Ph.D.
Central Nervous System Tumor Immunity Generated by a Recombinant
Listeria monocytogenes Vaccine Targeting Tyrosinase Related Protein-2 and
Real-Time Imaging of Intracranial Tumor Burden
Neurosurgery. 58(1):169-178, January 2006
Abstract
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Patrizia Tunici, Ph.D., Dwain Irvin,
Ph.D., M.P.H., Gentao Liu, Ph.D., Xiangpeng Yuan, Ph.D., Zeng Zhaohui,
Ph.D., Hiushan Ng, M.S., and John S. Yu, M.D.
Brain tumor stem cells: new
targets for clinical treatments?
Neurosurg Focus 20 (4):E27, April 2006

Abstract
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Cancer
Research
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Amy M. Hicks, Gregory
Riedlinger, Mark C. Willingham, Martha A.
Alexander-Miller, C. Von Kap-Herr, Mark J.
Pettenati, Anne M. Sanders, Holly M. Weir,
Wei Du, Joseph Kim, Andrew J. G. Simpson,
Lloyd J. Old, and Zheng Cui
Transferable anticancer innate immunity in spontaneous
regression/complete resistance mice
PNAS, May
16, 2006,
vol. 103 no. 20, pp.
7753-7758; Published
online before print May 8, 2006, 10.1073/pnas.0602382103
Abstract
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News
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Zhiya Yu and Nicholas P. Restifo
Cancer vaccines: progress reveals new
complexities
J. Clin. Invest. 110:289-294 (1 August 2002)
Abstract |
Full Text |
Reprint
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Choroid
Plexus Tumors
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Timothy
J, Chumas P, Chakrabarty A, Drake JM, Morrison E
Destruction of choroid plexus cells in vitro: a new concept
for the treatment of hydrocephalus
Neurosurgery. 2004 Mar;54(3):727-32
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Glioblastoma
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Aghi M, Rabkin S, Martuza RL.
Effect of Chemotherapy-Induced DNA Repair on
Oncolytic Herpes Simplex Viral Replication
Journal of the National Cancer Institute, Vol. 98, No. 1, 38-50, January 4, 2006
Abstract
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News
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Bryant NL, Suarez-Cuervo C, Gillespie GY,
Markert JM, Nabors LB, Meleth S, Lopez RD, Lamb LS Jr
Characterization and immunotherapeutic potential of {gamma}{delta} T
cells in patients with glioblastoma
Neuro Oncol. 2009 Feb 11; [Epub ahead of print]
Abstract
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Chamberlain
MC.
How Fine a Slice: Treatment of
Newly Diagnosed Glioblastoma With an Epidermal Growth Factor Receptor
Variant III Peptide Vaccine.
J Clin Oncol. 2011
May 9;. [Epub ahead of print]
Abstract |
Reprint |
Related articles
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Cho DY, Yang WK, Lee HC, Hsu DM, Lin HL, Lin SZ, Chen CC, Harn HJ, Liu CL,
Lee WY, Ho LH.
Adjuvant Immunotherapy with Whole-Cell Lysate Dendritic Cells Vaccine for
Glioblastoma Multiforme: A Phase II Clinical Trial.
World Neurosurg. 2011 Nov 7;. [Epub ahead of print]
Abstract |
Related articles
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Finocchiaro
G, Pellegatta S.
Immunotherapy for glioma: getting closer to the clinical arena?
Curr Opin Neurol. 2011 Dec;24(6):641-7.
Abstract |
Related articles
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Jean WC, Spellman SR,
Wallenfriedman MA, Flores CT, Kurtz BP, Hall WA, Low WC
Effects of combined granulocyte-macrophage
colony-stimulating factor (GM-CSF), interleukin-2, and interleukin-12 based
immunotherapy against intracranial glioma in the rat
J Neurooncol. 2004 Jan;66(1-2):39-49. (Abstract+)
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Katakura
R, Suzuki Y, Sekine T, Sasaki YF, Fujimiya Y
Therapeutic Efficacy of Adoptive Cell Transfer on Survival of Patients with
Glioblastoma Multiforme: Case Reports
Case Rep Oncol. 2010 Apr 28;3(2):110-124
Abstract |
Full Text |
Reprint
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Keller DM
Vaccine Made of Glioblastoma Lysate
Prolongs Survival.
Report on the intervention of Isaac Yang, MD at the
American Association of Neurological Surgeons
(AANS) 79th Annual Meeting: Plenary Session I. Presented April 11, 2011, and
of a comment of Andrew Parsa, MD, PhD. on Dr. Yang's study.
Report |
News
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Lesniak MS.
Immunotherapy
for Glioblastoma: The Devil Is in the Details.
J
Clin Oncol. 2011 Jun 27. [Epub ahead of print]
Abstract |
Reprint |
Related articles
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Lowenstein
PR, Geffen D.
Cancer Vaccines in Glioma: How to Balance the Challenges of Small Trials,
Efficiency, and Potential Adverse Events.
J Clin Oncol. 2010 Oct 4;. [Epub ahead of print]
Abstract |
Full Text |
Reprint
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Ma YH, Yu JB, Yao HP, Zhan RY, Zheng JS
Treatment of intracerebral glioblastomas with g422 tumour cell vaccine in a
mouse model
J Int Med Res. 2008 Mar-Apr;36(2):308-13
Abstract |
Reprint
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McBride
WH.
Integration of adenovirus
thymidine kinase suicide-gene therapy with surgery and radiation therapy for
malignant glioma.
Future Oncol. 2012 Jan;8(1):17-20.
Abstract |
Related articles
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Motomura
K, Natsume A, Kishida Y, Higashi H, Kondo Y, Nakasu Y, Abe T, Namba H, Wakai
K, Wakabayashi T.
Benefits
of interferon-β and temozolomide combination therapy for newly
diagnosed primary glioblastoma with the unmethylated MGMT promoter: a
multicenter study.
Cancer. 2010 Nov
8. [Epub ahead of print]
Abstract |
Related articles
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Muragaki
Y, Maruyama T, Iseki H, Tanaka M, Shinohara C, Takakura K, Tsuboi K,
Yamamoto T, Matsumura A, Matsutani M, Karasawa K, Shimada K, Yamaguchi N,
Nakazato Y, Sato K, Uemae Y, Ohno T, Okada Y, Hori T.
Phase I/IIa trial of autologous
formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for
newly diagnosed glioblastoma.
J Neurosurg. 2011 May 13;. [Epub
ahead of print]
Abstract |
Related articles
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Akihiro Otsuki, Suzanne Camilli, Ankita Patel,
Shigeru Tanaka, E. Antonio Chiocca, and Yoshinaga Saeki
Characterizing an oncolytic virotherapy targeted towards brain tumor
stem cells
AACR Meeting Abstracts, Apr 2006; 2006: 703
Abstract
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Ian F. Parney, Lung-Ji Chang,
Maxine A. Farr-Jones, Chunhai Hao, Michael Smylie and
Kenneth C. Petruk
Technical hurdles in a pilot clinical trial of combined B7-2 and GM-CSF
immunogene therapy for glioblastomas and melanomas
J Neurooncol. 2006
May;78(1):71-80. Epub 2006 Apr 21. DOI: 10.1007/s11060-005-9058-0
Abstract
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Pellegatta S, Poliani PL, Stucchi E, Corno D, Colombo CA,
Orzan F, Ravanini M, Finocchiaro G.
Intra-tumoral dendritic cells increase efficacy of peripheral vaccination
by modulation of glioma microenvironment
Neuro Oncol. 2010 Apr;12(4):377-88. Epub 2010 Jan 6
Abstract
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Pellegatta, S., Poliani, P.L., Corno, D., Grisoli,
M., Cusimano, M., Ubiali,
F., Baggi, F., Bruzzone,
M.G., Finocchiaro, G.
Dendritic cells pulsed with glioma lysates induce immunity against
syngeneic intracranial gliomas and increase survival of tumor-bearing
mice
Neurological Research, Volume 28, Number 5, July 2006, pp. 527-531(5)
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Prins RM, Soto H, Konkankit V, Odesa SK, Eskin A, Yong WH, Nelson SF, Liau
LM.
Gene
expression profile correlates with T cell infiltration and survival in
glioblastoma patients vaccinated with dendritic cell immunotherapy.
Clin
Cancer Res. 2010 Dec 6. [Epub ahead of print]
Abstract |
Related articles |
News
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Stéphan Saikali, Tony Avril, Brigitte Collet,
Abderrahmane Hamlat, Jean-Yves Bansard, Bernard Drenou, Yvon Guegan
and Véronique Quillien
Expression of nine tumour antigens in a series of human glioblastoma
multiforme: interest of EGFRvIII, IL-13Rα2, gp100 and TRP-2 for
immunotherapy
J Neurooncol. 2006 Sep 27; [Epub
ahead of print]
Abstract
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Sakamoto
N, Ishikawa E, Yamamoto T, Satomi K, Nakai K, Sato M, Enomoto T, Morishita
Y, Takano S, Ohno T, Tsuboi K, Matsumura A.
Pathological changes after
autologous formalin-fixed tumor vaccine therapy combined with temozolomide
for glioblastoma.
Neurol Med Chir (Tokyo).
2011;51(4):319-25.
Release date 2011 Apr 25.
Abstract |
Reprint |
Related articles
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Schneider T,
Gerhards R, Kirches E, Firsching R
Preliminary
results of active specific immunization with modified tumor cell vaccine in
glioblastoma multiforme
J
Neurooncol 2001 May;53(1):39-46
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Söderlund J, Erhardt S, Kast RE.
Acyclovir
inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct.
J
Neuroinflammation. 2010 Aug 6;7:44.
Abstract |
Reprint |
Related articles
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Van Gool S, Maes W, Ardon H, Verschuere T, Van Cauter S, De
Vleeschouwer S
Dendritic cell therapy of high-grade gliomas
Brain Pathol. 2009 Oct;19(4):694-712. Published Online: 4 Sep 2009
Abstract |
Full Text |
Reprint
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Vauleon
E, Avril T, Collet B, Mosser J, Quillien V.
Overview of cellular immunotherapy for patients with glioblastoma.
Clin Dev Immunol. 2010;2010. Published online
2010 October 4.
Abstract |
Full Text |
Reprint |
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Wheeler
CJ
Dendritic cell vaccines to combat glioblastoma
Expert Rev Neurother. 2010 Apr;10(4):483-6
Abstract |
Full Text |
Reprint
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Wheeler CJ, Black KL, Liu G, Mazer M, Zhang XX,
Pepkowitz S, Goldfinger D, Ng H, Irvin D, Yu JS
Vaccination elicits correlated immune and clinical responses in
glioblastoma multiforme patients
Cancer Res. 2008
Jul 15;68(14):5955-64
Abstract |
Reprint
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Christopher J. Wheeler, Asha Das, Gentao
Liu, John S. Yu and Keith L. Black
Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy after
Vaccination
Clinical Cancer Research Vol. 10, 5316-5326, August 15, 2004
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Wu A, Oh S, Gharagozlou S, Vedi RN, Ericson K,
Low WC, Chen W, Ohlfest JR
In Vivo Vaccination With Tumor Cell Lysate Plus CpG Oligodeoxynucleotides
Eradicates Murine Glioblastoma
J Immunother (1997). 2007 November/December;30(8):789-797
Abstract
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Wu
AH, Hall WA,
Low WC.
Identification of HLA a*0201 glioblastoma multiforme
cell lines for immunotherapy by PCR-SSP and DNA sequencing
J Neurooncol. 2004 Jan;66(1-2):1-8. (Abstract+)
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Recurrent
Tumors
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De
Vleeschouwer S, Fieuws S, Rutkowski S, Van Calenbergh F, Van Loon J, Goffin
J, Sciot R, Wilms G, Demaerel P, Warmuth-Metz M, Soerensen N, Wolff JE,
Wagner S, Kaempgen E, Van Gool SW
Postoperative adjuvant dendritic cell-based immunotherapy in patients
with relapsed glioblastoma multiforme
Clin
Cancer Res. 2008 May 15;14(10):3098-104
Abstract
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R.
O. Dillman, C. Duma, P. M. Schiltz, C. Depriest, L. Beutel, K. Okamoto, C.
De Leon
Intracavitary placement of lymphokine-activated
killer (LAK) cells after resection of recurrent glioblastoma
39th ASCO Annual Meeting.
Chicago, IL. May 31-June 3, 2003. Abstract No.
434
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Prins RM, Soto H, Konkankit V, Odesa SK, Eskin A, Yong WH, Nelson SF, Liau
LM.
Gene
expression profile correlates with T cell infiltration and survival in
glioblastoma patients vaccinated with dendritic cell immunotherapy.
Clin
Cancer Res. 2010 Dec 6. [Epub ahead of print]
Abstract |
Related articles
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Terasaki M, Shibui S, Narita Y, Fujimaki T, Aoki T, Kajiwara K, Sawamura Y,
Kurisu K, Mineta T, Yamada A, Itoh K.
Phase
I Trial of a Personalized Peptide Vaccine for Patients Positive for Human
Leukocyte Antigen-A24 With Recurrent or Progressive Glioblastoma Multiforme.
J
Clin Oncol. 2010 Dec 13. [Epub ahead of print]
Abstract |
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Gliomas
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Amano
T, Kajiwara K, Yoshikawa K, Morioka J, Nomura S, Fujisawa H, Kato S, Fujii
M, Fukui M, Hinoda Y, Suzuki M.
Antitumor effects of vaccination with dendritic cells transfected with
modified receptor for hyaluronan-mediated motility mRNA in a mouse glioma
model.
J Neurosurg.
2007 Apr;106(4):638-45.
PMID: 17432716 [PubMed - in process]
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Koji Adachi
Synergistic
Antiglioma Activity of Interleukin-12 and Interleukin-18
15th International Conference on Brain Tumor Research and Therapy. Sorrento,
Italy. May 24–27, 2003. Abstract No. 1
Neuro-Oncology, Volume 5, CNO 4, October 2003
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Barba
D, Saris SC, Holder C, Rosenberg SA, Oldfield EH
Intratumoral
LAK cell and interleukin-2 therapy of human gliomas
J Neurosurg. 1989 Feb;
70(2): 175-82
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Ciesielski MJ, Apfel L, Barone TA, Castro CA, Weiss
TC, Fenstermaker RA
Antitumor effects of a xenogeneic survivin bone marrow derived dendritic
cell vaccine against murine GL261 gliomas
Cancer
Immunol Immunother. 2006 Dec;55(12):1491-503.
Epub 2006 Feb 17
Abstract
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K.
M. Dhodapkar, B. Cirignano, J. L. Finlay, R. M. Steinman
Invariant natural killer T cells are preserved in
patients with glioma and exhibit anti-tumor lytic activity
39th ASCO Annual Meeting.
Chicago, IL. May 31-June 3, 2003. Abstract No.
398
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Friese
MA, Platten M, Lutz SZ, Naumann U, Aulwurm S, Bischof F, Buhring HJ,
Dichgans J, Rammensee HG, Steinle A, Weller M
MICA/NKG2D-mediated
immunogene therapy of experimental gliomas
Cancer Res. 2003 Dec 15;63(24):8996-9006
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Grauer OM, Sutmuller RP, van Maren W, Jacobs JF,
Bennink E, Toonen LW, Nierkens S, Adema GJ.
Elimination of regulatory T cells is essential
for an effective vaccination with tumor lysate-pulsed dendritic cells in a
murine glioma model
Int
J Cancer. 2007 Dec 12; [Epub ahead of print]
Abstract
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Jinwei Hu, Xiangpeng Yuan,
Maria L. Belladonna, John M. Ong, Sebastian
Wachsmann-Hogiu, Daniel L. Farkas, Keith L. Black
and John S. Yu
Induction of Potent Antitumor Immunity by Intratumoral Injection of
Interleukin 23–Transduced Dendritic Cells
Cancer Research 66, 8887-8896, September 1, 2006
Abstract
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News
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Ulrich
Herrlinger, Steffen Aulwurm, Herwig Strik, Simone Weit, Ulrike Naumann
and Michael Weller
MIP-1α antagonizes the effect of a
GM-CSF-enhanced subcutaneous vaccine in a mouse glioma model
Journal of Neuro-Oncology 66: 147–154, January
2004. (Abstract+)
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Kjaergaard J, Wang LX, Kuriyama H, Shu S,
Plautz GE
Active immunotherapy for advanced
intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines
J Neurosurg. 2005
Jul;103(1):156-64
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Liau
LM, Black KL, Prins RM, Sykes SN, DiPatre PL, Cloughesy TF, Becker DP,
Bronstein JM
Treatment
of intracranial gliomas with bone marrow-derived dendritic cells pulsed with
tumor antigens
J
Neurosurg 1999 Jun;90(6):1115-24
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Maatta
AM, Liimatainen T, Wahlfors T, Wirth T, Vaha-Koskela M, Jansson L, Valonen P,
Hakkinen K, Rautsi O, Pellinen R, Makinen K, Hakumaki J, Hinkkanen A, Wahlfors
J.
Evaluation of cancer virotherapy with attenuated replicative Semliki forest
virus in different rodent tumor models.
Int
J Cancer. 2007 Apr 18; [Epub ahead of print]
PMID: 17443493 [PubMed - as supplied by publisher]
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Morioka
J, Kajiwara K, Yoshikawa K, Ideguchi M, Uchida T, Suzuki M
Vaccine
therapy for murine glioma using tumor cells genetically modified to express b7.1
Neurosurgery. 2004 Jan;54(1):182-90
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Newcomb EW, Demaria S, Lukyanov Y, Shao Y, Schnee T, Kawashima N, Lan L, Dewyngaert
JK, Zagzag D, McBride WH, Formenti SC
The combination of ionizing radiation and peripheral vaccination produces
long-term survival of mice bearing established invasive GL261 gliomas
Clin
Cancer Res. 2006 Aug 1;12(15):4730-7
Abstract |
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Reprint
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Okada
H, Pollack IF.
Do we need novel radiologic
response criteria for brain tumor immunotherapy?
Expert Rev Neurother. 2011 May;11(5):619-22.
Abstract |
Reprint |
Related articles
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Prins RM,
Odesa SK, Liau LM
Immunotherapeutic
Targeting of Shared Melanoma-Associated Antigens in a Murine Glioma Model
Cancer Res. 2003 Dec 1;63(23):8487-8491
|
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Shah
AC, Parker JN, Gillespie GY, Lakeman FD, Meleth S, Markert JM, Cassady
KA.
Enhanced antiglioma activity of chimeric HCMV/HSV-1
oncolytic viruses.
Gene Ther. 2007 Apr
12; [Epub ahead of print]
PMID: 17429445 [PubMed - as supplied by publisher]
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Spagnolo
A, Glick RP, Lin H, Cohen EP, Feinstein DL, Lichtor T
Prolonged survival of mice with established intracerebral glioma receiving
combined treatment with peroxisome proliferator-activated receptor-gamma
thiazolidinedione agonists and interleukin-2-secreting syngeneic/allogeneic
fibroblasts
J Neurosurg.
2007 Feb;106(2):299-305
Abstract
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Vetter M, Hofer MJ, Roth E, Pircher HP,
Pagenstecher A
Intracerebral
Interleukin 12 Induces Glioma Rejection in the Brain Predominantly by CD8+ T
Cells and Independently of Interferon-gamma
J
Neuropathol Exp Neurol. 2009 May;68(5):525-34
Abstract
|
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Wheeler
CJ, Black KL
Dendritic
cell vaccines and obstacles to beneficial immunity in glioma patients
Curr Opin Mol Ther.
2005 Feb;7(1):35-47. Epub 2005 Jan 26
Abstract
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Yamini B, Yu X, Pytel P, Galanopoulos N, Rawlani
V, Veerapong J, Bickenbach K, Weichselbaum RR
Adenovirally delivered tumor necrosis
factor-alpha improves the antiglioma efficacy of concomitant radiation and
temozolomide therapy
Clin
Cancer Res. 2007 Oct 15;13(20):6217-23
Abstract
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Xiang-Peng Yuan, Jinwei Hu, Gentao Liu, Zhaohui
Zheng, Patrizia Tunici, Yasuharu Akasaki, Takayuki Yoshimoto, Keith L.
Black, and John S. Yu
Neural stem cell can mediate immune therapy for brain tumor
AACR Meeting Abstracts, Apr 2006; 2006: 241
Abstract
|
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Xiangpeng Yuan, Jinwei Hu,
Maria L. Belladonna, Keith L. Black and John
S. Yu
Interleukin-23–Expressing Bone Marrow–Derived Neural Stem-Like
Cells Exhibit Antitumor Activity against Intracranial Glioma
Cancer Research 66, 2630-2638, March 1, 2006
Abstract
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Gliomas
(High-Grade)
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Chang CN, Huang YC, Yang DM, Kikuta K, Wei KJ, Kubota T, Yang WK.
A
phase I/II clinical trial investigating the adverse and therapeutic effects
of a postoperative autologous dendritic cell tumor vaccine in patients with
malignant glioma.
J
Clin Neurosci. 2011 Aug;18(8):1048-54. Epub 2011 Jun 28.
Abstract |
Related articles
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Chiocca EA, Aguilar LK, Bell SD, Kaur B, Hardcastle J, Cavaliere R, McGregor
J, Lo S, Ray-Chaudhuri A, Chakravarti A, Grecula J, Newton H, Harris KS,
Grossman RG, Trask TW, Baskin DS, Monterroso C, Manzanera AG,
Aguilar-Cordova E, New PZ.
Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to
Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma.
J
Clin Oncol. 2011 Aug 15. [Epub ahead of print]
Abstract |
Related articles
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Choi
BD, Archer GE, Mitchell DA, Heimberger AB, McLendon RE, Bigner DD, Sampson
JH
EGFRvIII-targeted
vaccination therapy of malignant glioma
Brain
Pathol. 2009 Oct;19(4):713-23.
Published Online: 4 Sep 2009
Abstract |
Full Text |
Reprint
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Grauer
OM, Wesseling P, Adema GJ
Immunotherapy
of diffuse gliomas: biological background, current status and future
developments
Brain
Pathol. 2009 Oct;19(4):674-93.
Published Online: 4 Sep 2009
Abstract |
Full Text |
Reprint
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Gromeier
M, Lachmann S, Rosenfeld MR, Gutin PH, Wimmer E
Intergeneric
poliovirus recombinants for the treatment of malignant glioma
Proc
Natl Acad Sci U S A 2000 Jun 6;97(12):6803-8 (PDF Full Text)
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Gentao Liu, Keith L
Black and John S Yu
Sensitization of malignant glioma to
chemotherapy through dendritic cell vaccination
Expert Review of Vaccines, Apr 2006, Vol. 5, No. 2, Pages 233-247
Abstract
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Hickey MJ, Malone CC, Erickson KL, Jadus MR, Prins RM, Liau LM, Kruse CA.
Cellular
and vaccine therapeutic approaches for gliomas.
J Transl Med.
2010 Oct 14;8:100.
Abstract |
Reprint |
Related articles
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|
Lun XQ, Jang JH, Tang N, Deng H, Head R, Bell JC, Stojdl DF, Nutt CL, Senger DL,
Forsyth PA, McCart JA
Efficacy
of systemically administered oncolytic vaccinia virotherapy for malignant
gliomas is enhanced by combination therapy with rapamycin or
cyclophosphamide
Clin
Cancer Res. 2009 Apr 15;15(8):2777-88. Epub 2009 Apr 7
Abstract
|
|
|
XueQing Lun, Donna L. Senger, Tommy Alain,
Andra Oprea, Kelley Parato, Dave Stojdl, Brian
Lichty, Anthony Power, Randal N. Johnston, Mark
Hamilton, Ian Parney, John C. Bell, Peter
A. Forsyth
Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus
(VSVΔM51) on Multifocal and Invasive Gliomas
Journal of the National Cancer Institute, Vol. 98, No. 21,
1546-1557, November 1, 2006
Abstract
|
Full
Text |
Reprint
|
News
|
|
|
Serena Pellegatta, Pietro Luigi Poliani, Daniela
Corno, Francesca Menghi, Francesco Ghielmetti, Blanca Suarez-Merino,
Valentina Caldera, Sara Nava, Maria Ravanini, Fabio Facchetti, Maria Grazia
Bruzzone, and Gaetano Finocchiaro
Neurospheres Enriched in Cancer Stem–Like Cells Are Highly
Effective in Eliciting a Dendritic Cell–Mediated Immune Response against
Malignant Gliomas
Cancer Res 2006 Nov 1; 66: 10247-10252
|
|
Plautz
GE, Barnett GH, Miller DW, Cohen BH, Prayson RA, Krauss JC, Luciano M,
Kangisser DB, Shu S
Systemic
T cell adoptive immunotherapy of malignant gliomas
J
Neurosurg 1998 Jul;89(1):42-51
|
|
Salazar AM, Levy HB, Ondra S, Kende M, Scherokman B, Brown D, Mena H, Martin
N, Schwab K, Donovan D, Dougherty D, Pulliam M, Ippolito M, Graves M, Brown H,
Ommaya A
Long-term treatment of malignant gliomas with intramuscularly
administered polyinosinic-polycytidylic acid stabilized with polylysine and
carboxymethylcellulose: an open pilot study
Neurosurgery 1996 Jun;38(6):1096-103
|
|
|
Smith KE, Fritzell S, Badn W, Eberstål S,
Janelidze S, Visse E, Darabi A, Siesjö P
Cure of established GL261 mouse gliomas after combined immunotherapy with
GM-CSF and IFNgamma is mediated by both CD8(+) and CD4(+) T-cells
Int
J Cancer. 2008 Sep 9. [Epub ahead of print]
Abstract
|
|
|
Christopher J. Wheeler, Asha
Das, Gentao Liu, John S. Yu and Keith
L. Black
Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy
after Vaccination
Clinical Cancer Research Vol. 10, 5316-5326, August 15,
2004
Abstract
|
Full
Text |
Reprint
|
|
|
Wakabayashi
T, Kayama T, Nishikawa R, Takahashi H, Hashimoto N, Takahashi J, Aoki T,
Sugiyama K, Ogura M, Natsume A, Yoshida J.
A multicenter phase I trial of combination therapy with
interferon-β and
temozolomide for high-grade gliomas (INTEGRA study): the final report.
J Neurooncol. 2011 Feb 14;. [Epub ahead of print]
Abstract |
Related articles
|
|
|
Wakabayashi T, Kayama T, Nishikawa R, Takahashi H, Yoshimine T, Hashimoto N,
Aoki T, Kurisu K, Natsume A, Ogura M, Yoshida J.
A
multicenter phase I trial of interferon-beta and temozolomide combination
therapy for high-grade gliomas (INTEGRA Study).
Jpn J Clin
Oncol. 2008 Oct;38(10):715-8.
Abstract |
Reprint |
Related articles
|
|
|
Wesseling
P, Adema GJ
Immunotherapy
of diffuse gliomas: helping the brain fight back!
Brain
Pathol. 2009 Oct;19(4):672-3.
Published Online: 4 Sep 2009
Abstract |
Full Text |
Reprint
|
|
Wilcox
ME, Yang W, Senger D, Rewcastle NB, Morris DG, Brasher PM, Shi ZQ, Johnston
RN, Nishikawa S, Lee PW, Forsyth PA
Reovirus as an oncolytic agent against experimental
human malignant gliomas
J
Natl Cancer Inst 2001 Jun 20;93(12):903-12
|
|
|
Wu
A, Wiesner S, Xiao J, Ericson K, Chen W, Hall WA, Low WC, Ohlfest JR
Expression of MHC I and NK ligands on human CD133+ glioma cells: possible
targets of immunotherapy
J Neurooncol.
2007 Jun;83(2):121-31.
Epub 2006 Nov 1. Erratum in: J Neurooncol. 2007 Jun;83(2):133
Abstract |
Reprint
|
|
John S. Yu, Gentao Liu,
Han Ying, William H. Yong,
Keith L. Black and Christopher J.
Wheeler
Vaccination with Tumor Lysate-Pulsed Dendritic Cells Elicits
Antigen-Specific, Cytotoxic T-Cells in Patients with Malignant Glioma
Cancer Research 64, 4973-4979, July 15, 2004
|
|
Recurrent
Tumors
|
|
|
Hayes
RL, Koslow M, Hiesiger EM, Hymes KB, Hochster HS, Moore EJ, Pierz DM, Chen
DK, Budzilovich GN, Ransohoff J
Improved long
term survival after intracavitary interleukin-2 and lymphokine-activated killer
cells for adults with recurrent malignant glioma
Cancer
1995 Sep 1;76(5):840-52
|
|
|
Okada H, Kalinski P, Ueda R, Hoji A, Kohanbash G, Donegan TE, Mintz AH, Engh
JA, Bartlett DL, Brown CK, Zeh H, Holtzman MP, Reinhart TA, Whiteside TL,
Butterfield LH, Hamilton RL, Potter DM, Pollack IF, Salazar AM, Lieberman
FS.
Induction
of CD8+ T-Cell Responses Against Novel Glioma-Associated Antigen Peptides
and Clinical Activity by Vaccinations With {alpha}-Type 1 Polarized
Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and
Carboxymethylcellulose in Patients With Recurrent Malignant Glioma.
J
Clin Oncol. 2010 Dec 13. [Epub ahead of print]
Abstract |
Related articles
|
|
Rampling
R, Cruickshank G, Papanastassiou V, Nicoll J, Hadley D, Brennan D, Petty R,
MacLean A, Harland J, McKie E, Mabbs R, Brown M
Toxicity
evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant
1716) in patients with recurrent malignant glioma
Gene
Ther 2000 May;7(10):859-66
|
|
Koji Tsuboi,
Kaoru Saijo, Eiichi Ishikawa, Hideo Tsurushima,
Shingo Takano, Yukio Morishita and Tadao Ohno
Effects of Local Injection of ex Vivo Expanded Autologous
Tumor-specific T Lymphocytes in Cases with Recurrent Malignant Gliomas
Clinical Cancer Research Vol. 9, 3294-3302, August 2003. (PDF Full Text)
|
|
|
Laboratory
Research
|

|
|
|
Haapasalo
J, Nordfors K, Jarvela S, Bragge H, Rantala I, Parkkila AK, Haapasalo H,
Parkkila S.
Carbonic anhydrase II in the endothelium of glial tumors: A potential
target for therapy.
Neuro-oncol. 2007 Apr
13; [Epub ahead of print]
PMID: 17435181 [PubMed - as supplied by publisher]
|
|
Roth
P, Mittelbronn M, Wick W, Meyermann R, Tatagiba M, Weller M.
Malignant Glioma Cells Counteract Antitumor Immune Responses through
Expression of Lectin-Like Transcript-1.
Cancer Res. 2007 Apr
15;67(8):3540-4.
PMID: 17440061 [PubMed - in process]
|
|
|
Medulloblastoma
|

|
|
|
Peter
A Forsyth, Wen Qing Yang, Donna Senger, Huong Muzik, Zhong Q Shi, Penny
Brasher, Richard Dyck
Reovirus
oncolysis in medulloblastoma is effective in vivo and safe in rodents and
primates
38th
ASCO Annual Meeting. Orlando, FL. May 18-21, 2002.
Abstract No.
289
|
|
|
Neuroblastoma |

|
|
|
A. Batova, A. L. Yu, D. Strother,
P. Angelini, A. Eskenazi
Promising results of a pilot trial of a GD2
directed anti-idiotypic antibody as a vaccine for high risk neuroblastoma
40th
ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.8511
|
|
|
Joshi AD, Clark EM, Wang P, Munger CM, Hegde GV,
Sanderson S, Dave HP, Joshi SS
Immunotherapy of human neuroblastoma using umbilical cord blood-derived
effector cells
J
Neuroimmune Pharmacol. 2007 Jun;2(2):202-12.
Epub 2006 Oct 11
Abstract
|
|
|
Tahira Khan,
Julie A.
Hixon, Jimmy K. Stauffer, Erin Lincoln, Timothy
C. Back, Jason Brenner, Stephen Lockett, Kunio
Nagashima, Douglas Powell, Jon M. Wigginton
Therapeutic Modulation of Akt Activity and
Antitumor Efficacy of Interleukin-12 Against Orthotopic Murine Neuroblastoma
Journal of the National Cancer Institute, Vol. 98, No. 3, 190-202, February 1,
2006
Abstract
|
News
|
|
|
Mario Otto,
Raymond C. Barfield, William
J. Martin, Rekha Iyengar,
Wing Leung, Thasia
Leimig, Stanley Chaleff,
Stephen D. Gillies and Rupert
Handgretinger
Combination Immunotherapy with Clinical-Scale
Enriched Human γδ T cells, hu14.18 Antibody, and the Immunocytokine
Fc-IL7 in Disseminated Neuroblastoma
Clinical Cancer Research Vol. 11, 8486-8491, December 1, 2005
Abstract
|
News
|
|
|
Non-CNS
Tumors
|

|
|
| |
Batliwalla
FM, Bateman BA, Serrano D, Murray D, Macphail S, Maino VC, Ansel JC,
Gregersen PK, Armstrong CA
A 15-year
follow-up of AJCC stage III malignant melanoma patients treated postsurgically
with Newcastle disease virus (NDV) oncolysate and determination of alterations
in the CD8 T cell repertoire
Mol
Med 1998 Dec;4(12):783-94
|
|
Csatary
LK, Eckhardt S, Bukosza I, Czegledi F, Fenyvesi C, Gergely P, Bodey B,
Csatary CM
Attenuated
veterinary virus vaccine for the treatment of cancer
Cancer
Detect Prev 1993;17(6):619-27
|
|
Grant
SC, Kris MG, Houghton AN, Chapman PB
Long
survival of patients with small cell lung cancer after adjuvant treatment with
the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guerin
Clin Cancer Res 1999 Jun;5(6):1319-23
|
|
Pecora AL, Rizvi N, Cohen GI, Meropol NJ, Sterman D, Marshall JL,
Goldberg S, Gross P, O'Neil JD, Groene WS, Roberts MS, Rabin H, Bamat MK,
Lorence RM
Phase I
trial of intravenous administration of PV701, an oncolytic virus, in patients
with advanced solid cancers
J
Clin Oncol 2002 May 1;20(9):2251-66
|

|