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Monoclonal Antibodies

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Malignant Lymphoma


F. G. El Kamar, L. M. Deangelis, J. Yahalom, D. D. Correa, B. W. Grant, R. V. Larocca, J. J. Raizer, D. Schiff, L. E. Abrey
Combined immunochemotherapy with reduced dose whole brain radiotherapy (WBRT) for newly diagnosed patients with primary CNS lymphoma (PCNSL)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1518

H. Schulz, H. Pels, U. Schlegel, U. Zeelen, U. Germing, A. Engert
Intraventricular application of rituximab as a treatment option in patients with CNS lymphoma and leptomeningeal disease
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1521

A. Torres-Trejo, J. L. Mabold, F. S. Lieberman, S. C. Schold
Rituximab as an alternative treatment for primary central nervous system lymphoma (PCNSL)
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 490


Metastatic Tumors


Grossi PM, Ochiai H, Archer GE, McLendon RE, Zalutsky MR, Friedman AH, Friedman HS, Bigner DD, Sampson JH
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer

Clin Cancer Res. 2003 Nov 15;9(15):5514-20. (PDF Full Text)

A. M. Scott, S. S. Gill, F. Lee, Z. Liu, E. Skrinos, C. Murone, T. Saunder, B. Chappell, A. Papenfuss, L. J. Old
A Phase I single dose escalation trial of ch806 in patients with advanced tumors expressing the 806 antigen
Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings Part I. Vol 24, No. 18S (June 20 Supplement), 2006: 13028
Abstract | News


Neuroblastoma


A. L. Yu, A. Batova, R. Gribi, M. Diccianni, L. Bridgeman, D. Geske, W. London, A. Gilman, F. Ozkaynak
Antibody-dependent cellular cytotoxicity (ADCC) in COG ANBL0032: A phase III randomized trial of chimeric anti-GD2 and GM-CSF/IL2 in high risk neuroblastoma following myeloablative therapy and autologous stem cell transplant (ASCT)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.2582


Non-CNS Tumors


Baselga J, Tripathy D, Mendelsohn J, Baughman S, Benz CC, Dantis L, Sklarin NT, Seidman AD, Hudis CA, Moore J, Rosen PP, Twaddell T, Henderson IC, Norton L
Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer
Semin Oncol 1999 Aug;26(4 Suppl 12):78-83

Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, Tripathy D, Baly D, Baughman SA, Twaddell T, Glaspy JA, Slamon DJ
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
J Clin Oncol 1998 Aug;16(8):2659-71


Grillo-Lopez AJ, White CA, Varns C, Shen D, Wei A, McClure A, Dallaire BK
Overview of the clinical development of rituximab: first monoclonal antibody approved for the treatment of lymphoma
Semin Oncol 1999 Oct;26(5 Suppl 14):66-73

Udo Vanhoefer, Mitra Tewes, Federico Rojo, Olaf Dirsch, Norbert Schleucher, Oliver Rosen, Joachim Tillner, Andreas Kovar, Ada H. Braun, Tanja Trarbach, Siegfried Seeber, Andreas Harstrick, José Baselga
Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor
Journal of Clinical Oncology, Vol 22, No 1 (January 1), 2004: pp. 175-184

 

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