Treatment > Nonsteroidal Anti-Inflammatory Drugs


Angiogenesis


Gately S
The contributions of cyclooxygenase-2 to tumor angiogenesis

Cancer Metastasis Rev 2000;19(1-2):19-27


Jones MK, Wang H, Peskar BM, Levin E, Itani RM, Sarfeh IJ, Tarnawski AS
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing
Nat Med 1999 Dec;5(12):1418-23


Glioblastoma


Amin R, Kamitani H, Sultana H, Taniura S, Islam A, Sho A, Ishibashi M, Eling TE, Watanabe T
Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells
Neurol Res. 2003 Jun;25(4):370-6 

Grossman SA, Olson J, Batchelor T, Peereboom D, Lesser G, Desideri S, Ye X, Hammour T, Supko JG
Effect of phenytoin on celecoxib pharmacokinetics in patients with glioblastoma
Neuro Oncol. 2008 Feb 20; [Epub ahead of print]
 Abstract |
DBLinks | BL 7:5

Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J, Kieran M, Wen PY.
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults
Neuro Oncol. 2008 Apr 10; [Epub ahead of print]
 Abstract |
DBLinks | BL 7:8

S. Pannullo, S. Hariharan, J. Serventi, R. Hayes, C. Balmaceda, J. Burton
Phase I/II trial of a twice-daily regimen of temozolomide and celecoxib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1549

S. Pannullo, J. V. Serventi, C. Balmaceda, J. Burton
Temozolomide plus celecoxib for treatment of malignant gliomas
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 455


Metastatic Tumors


Leandro C. A. Cerchietti, Marcelo R. Bonomi, Alfredo H. Navigante, Monica A. Castro, Maria E. Cabalar and Berta M. C. Roth
Phase I/II study of selective cyclooxygenase-2 inhibitor celecoxib as a radiation sensitizer in patients with unresectable brain metastases
Journal of Neuro-Oncology, 71(1): 73-81, January 2005. (Abstract+)


Non-Nervous System Tumors


Arber N, DuBois RN
Nonsteroidal anti-inflammatory drugs and prevention of colorectal cancer
Curr Gastroenterol Rep 1999 Oct;1(5):441-8 


Alshafie GA, Abou-Issa HM, Seibert K, Harris RE
Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model
Oncol Rep 2000 Nov-Dec;7(6):1377-81

Nasser K Altorki, Roger S Keresztes, Jeffrey L Port, Douglas B Flieder, Cathy A Ferrara, Mark W Pasmantier, Daniel M Libby, David Yankelevitz, Andrew J Dannenberg
Celecoxib (Celebrex), a selective COX-2 inhibitor, enhances the response to preoperative paclitaxel/carboplatin in early stage non-small cell lung cancer

ASCO Proceedings, 2002 Annual Meeting, Abstract No. 101


 

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