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Treatment
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Phenylbutyrate (and
Phenylacetate) |
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Cancer
Research
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Jihong Chen,
Feras M Ghazawi, Wafae Bakkar and Qiao Li
Valproic acid
and butyrate induce apoptosis in human cancer cells through inhibition
of gene expression of Akt/protein kinase B
 Molecular Cancer 2006, 5:71,
doi:10.1186/1476-4598-5-71, Published 11 December 2006
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Gliomas
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Matthew J.
Baker, Steven Brem, Stephanie Daniels, Beverly Sherman, Surasak Phuphanich
Complete Response of a Recurrent,
Multicentric Malignant Glioma in a Patient Treated with Phenylbutyrate
Journal
of Neuro-Oncology,
59
(3): 239-242, September 2002 (Case Report, Abstract)
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Chang
SM, Kuhn JG, Robins HI, Schold SC, Spence AM, Berger MS, Mehta MP, Bozik ME,
Pollack I, Schiff D, Gilbert M, Rankin C, Prados MD
Phase
II study of phenylacetate in patients with recurrent malignant glioma: a North
American Brain Tumor Consortium report
J Clin Oncol 1999 Mar;17(3):984-90 (Clinical Study, Abstract)
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Engelhard
HH, Homer RJ, Duncan HA, Rozental J
Inhibitory
effects of phenylbutyrate on the proliferation, morphology, migration and
invasiveness of malignant glioma cells
J Neurooncol 1998 Apr;37(2):97-108 (Cell Culture Study,
Abstract)
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Hidemitsu Nakagawa
Intrathecal or intracavitary administration of sodium butyrate
to treat neoplastic meningitis and malignant glioma
Proceedings of the AACR, Volume 45, March 2004,
Abstract Number: 5241. (Animal Study)
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Linz U
Complete response of a recurrent, multicentric
malignant glioma in a patient treated with phenylbutyrate
J Neurooncol. 2004 Jan;66(1-2):251; author reply 251. (Comment/Letter,
Reference+)
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Promyelocytic
Leukemia
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Zheng
X, Chang RL, Cui XX, Kelly KA, Shih WJ, Lin Y, Strair R, Suh J, Han ZT,
Rabson A, Conney AH
Synergistic
effects of clinically achievable concentrations of
12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic
acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in
HL-60 cells
Oncol Res 2000;12(9-10):419-27 (Cell Culture Study,
Abstract)
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Non-Nervous
System Tumors
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Pili
R, Kruszewski MP, Hager BW, Lantz J, Carducci MA
Combination
of phenylbutyrate and 13-cis retinoic acid inhibits prostate tumor growth and
angiogenesis
Cancer
Res 2001 Feb 15;61(4):1477-85 (Cell Culture Study,
Abstract & Full Text)
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