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Procarbazine

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Contents


Astrocytoma


Jeffrey G Supko, Xiaoying He, Carolyn Whitney, Tracy Batchelor, Thomas Mikkelsen, Jane Alavi, Surasak Phuphanich, Stuart Grossman
Pharmacokinetics of procarbazine and metabolites involved in its bioactivation in patients with recurrent anaplastic astrocytoma
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No.
2086  


Glioblastoma


Alba Ariela Brandes, Mario Ermani, Umberto Basso, Lara Maria Pasetto, Francesca Vastola, Franco Berti, Silvia Berlucchi, Pietro Amistà, Antonello Rotilio, Silvio Monfardini
Procarbazine Prior to and Concomitant with BCNU in Patients with Glioblastoma at First Relapse: a Phase II Study
ASCO Proceedings, 2001 Annual Meeting, Abstract 


R Albright, M Brada, J Brunner, MH Dugan, K Fink, R Fredericks, VA Levin, J Olson, M Prados, A Spence, N Yue, A Yung, S Zaknoen
Randomized Trial of Temodal (TEM) Vs. Procarbazine (PCB) in Glioblastoma Multiforme (GBM) at First Relapse
ASCO Proceedings, 1999 Annual Meeting, Abstract 


Yung WK, Albright RE, Olson J, Fredericks R, Fink K, Prados MD, Brada M, Spence A, Hohl RJ, Shapiro W, Glantz M, Greenberg H, Selker RG, Vick NA, Rampling R, Friedman H, Phillips P, Bruner J, Yue N, Osoba D, Zaknoen S, Levin VA.
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
Br J Cancer 2000 Sep;83(5):588-93 

Recurrent Tumors


Osoba D, Brada M, Yung WK, Prados M.
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme

J Clin Oncol 2000 Apr;18(7):1481-91 (PDF Full Text)


Silvani A, Lamperti E, Gaviani P, Eoli M, Fiumani A, Salmaggi A, Falcone C, Filippini G, Botturi A, Boiardi A.
Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients
J Neurooncol. 2008 Apr;87(2):143-51. Epub 2007 Jun 19. Erratum in: J Neurooncol. 2008 Aug;89(1):119. J Neurooncol. 2008 Apr;87(2):153.
  Abstract |   Reprint |   Related articles


Gliomas (High-Grade)


Beith J., Cook R., Robinson B., Levi J., Bell D., Wheeler H. 
Modulation of resistance to BCNU by depleting MGMT activity with procarbazine in patients with relapsed high-grade gliomas

ASCO Proceedings, 1997 Annual Meeting, Abstract No. 1375 

Boiardi A, Silvani A, Ciusani E, Watson A, Margison G, Berger E, Lucas C, Giroux B
Fotemustine combined with procarbazine in recurrent malignant gliomas: a phase I study with evaluation of lymphocyte 06-alkylguanine-DNA alkyltransferase activity

J Neurooncol 2001 Apr;52(2):149-56  


Brandes AA, Ermani M, Turazzi S, Scelzi E, Berti F, Amista P, Rotilio A, Licata C, Fiorentino MV
Procarbazine and high-dose tamoxifen as a second-line regimen in recurrent high-grade gliomas: a phase II study

J Clin Oncol 1999 Feb;17(2):645-50 (PDF Full Text)

Dufour C, Grill J, Lellouch-Tubiana A, Puget S, Chastagner P, Frappaz D, Doz F, Pichon F, Plantaz D, Gentet JC, Raquin MA, Kalifa C.
High-grade glioma in children under 5 years of age: A chemotherapy only approach with the BBSFOP protocol.
Eur J Cancer. 2006 Sep 6; [Epub ahead of print]
Abstract


Huang F, Kavan P, Guiot MC, Markovic Y, Roberge D
When temozolomide alone fails: adding procarbazine in salvage therapy of glioma
Can J Neurol Sci. 2008 May;35(2):192-7
 Abstract

Newlands ES, Foster T, Zaknoen S
Phase I study of temozolomide (TMZ) combined with procarbazine (PCB) in patients with gliomas
Br J Cancer. 2003 Jul 21;89(2):248-51. 

Ruiz J, Case D, Enevold G, Rosdhal R, Tatter SB, Ellis TL, McQuellon RP, McMullen KP, Stieber VW, Shaw EG, Lesser GJ.
A phase II trial of thalidomide and procarbazine in adult patients with recurrent or progressive malignant gliomas.
J Neurooncol. 2011 Aug 26. [Epub ahead of print]
  Abstract |   Related articles

Slancar M., Wheeler H., Cook R., Levi J., Bell D., Beith J.
Increased pulmonary toxicity with scheduling procarbazine prior to BCNU in patients with high-grade gliomas

ASCO Proceedings, 1997 Annual Meeting, Abstract No. 1459 


Gliomatosis Cerebri


Glas M, Bähr O, Felsberg J, Rasch K, Wiewrodt D, Schabet M, Simon M, Urbach H, Steinbach JP, Rieger J, Fimmers R, Bamberg M, Nägele T, Reifenberger G, Weller M, Herrlinger Md U, Group Of The German Cancer Society FT.
NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri.
Ann Neurol. 2011 May 11. [Epub ahead of print]
  Abstract |   Related articles

 

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