BRAINLIFE Brain Tumor Medical Database

Rapamycin

Home > Database > Treatment > Rapamycin (Rapamune, Sirolimus)

Contents


Glioblastoma


Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, Hsueh T, Chen Y, Wang W, Youngkin D, Liau L, Martin N, Becker D, Bergsneider M, Lai A, Green R, Oglesby T, Koleto M, Trent J, Horvath S, Mischel PS, Mellinghoff IK, Sawyers CL
Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma
PLoS Med. 2008 Jan 22;5(1):e8. [Epub ahead of print]
Abstract | Full Text | Reprint

A. Das, M. Badruddoja, D. Tryciecky, J. Yu and K. Black
Phase I study of gefitinib and rapamycin in patients with recurrent or progressive glioblastoma (Gbm)
2005 ASCO Annual Meeting. Orlando, FL. May 13-17. Abstract No. 1572
Journal of Clinical Oncology, Vol 23, No 16S (June 1 Supplement), 2005: 1572

Reardon DA, Desjardins A, Vredenburgh JJ, Gururangan S, Friedman AH, Herndon JE 2nd, Marcello J, Norfleet JA, McLendon RE, Sampson JH, Friedman HS
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
J Neurooncol. 2009 Jun 28. [Epub ahead of print]
  Abstract


Gliomas


Amy B. Heimberger, Enze Wang, Eric C. McGary, Kenneth R. Hess, Verlene K. Henry, Tadahisa Shono, Zvi Cohen, Joy Gumin, Raymond Sawaya, Charles A. Conrad, and Frederick F. Lang
Mechanisms of action of rapamycin in gliomas
Neuro-Oncology, Volume 7, Number 1, Pages 1--11, January 2005. (Abstract+)

Zhuang WZ, Long LM, Ji WJ, Liang ZQ.
Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy.
Chin J Cancer. 2011 Oct;30(10):712-20.
  Abstract |   Reprint |   Related articles


Tumors

Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber M, Jauch KW, Geissler EK
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

Nat Med 2002 Feb;8(2):128-35

Thuy L. Phung, Keren Ziv, Donnette Dabydeen, Godfred Eyiah-Mensah, Marcela Riveros, Carole Perruzzi, Jingfang Sun, Rita A. Monahan-Earley, Ichiro Shiojima, Janice A. Nagy, Michelle I. Lin, Kenneth Walsh, Ann M. Dvorak, David M. Briscoe, Michal Neeman, William C. Sessa, Harold F. Dvorak, and Laura E. Benjamin
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
Cancer Cell, Vol 10, 159-170, August 2006. Published: August 14, 2006.

 

This website is certified by Health On the Net Foundation. Click to verify. HOMECURRENT NEURO-ONCOLOGYGLIOBLASTOMA REPORTSBRAIN TUMOR MEDICAL DATABASE SERVICES TREATMENT OPTIONS FOR GLIOBLASTOMA
DATABASE by Section: Classification | Diagnosis | Epidemiology | Etiology & Pathogenesis | Integrative Medicine | Overall Management | Prognosis | Psychosocial Aspects | Stem Cells | Treatment
DATABASE by Tumor: Glioblastoma | Medulloblastoma | Other TumorsSERVICES: About BrainLife | Children's Corner | Dedication | E-mail Alerts | Journals | Privacy Policy | Publications | Search | SiteMap
This site complies with the HONcode standard for trustworthy health information: verify here bottom