Treatment > Retinoids


Glioblastoma

Das A, Banik NL, Ray SK.
Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells.
J Neurooncol. 2007 Nov 7; [Epub ahead of print]
Abstract

Melino G, Stephanou A, Annicchiarico-Petruzzelli M, Finazzi-Agro A, Knight RA, Lightman SL
IGF-II mRNA expression in LI human glioblastoma cell line parallels cell growth
Neurosci Lett. 1992 Sep 14;144(1-2):25-8 (Cell Culture Study, Abstract)

Siew-Ju See, Victor A. Levin, W.-K. Alfred Yung, Kenneth R. Hess, Morris D. Groves
13-cis-Retinoic acid in the treatment of recurrent glioblastoma multiforme
Neuro-Oncology, Vol. 6, No. 3, July 2004, 253 -- 258. (Retrospective Study, Abstract+)


Gliomas

Caecilia Wismeth, Peter Hau, Klaus Fabel, Ulrike Baumgart, Birgit Hirschmann, Horst Koch, Tanja Jauch, Oliver Grauer, Lisa Drechsel, Alexander Brawanski, Ulrich Bogdahn, Andreas Steinbrecher
Maintenance Therapy with 13-cis Retinoid Acid in High-Grade Glioma at Complete Response After First-Line Multimodal Therapy – A Phase-II Study
Journal of Neuro-Oncology, 68 (1): 79-86, May 2004. (Clinical Study, Abstract+)

Klaus Fabel, Peter Hau, Oliver Grauer, Tanya Jauch, Martin Proescholdt, Anton Zellner, Andreas Steinbrecher, Alexander Brawanski, Ulrich Bogdahn
Neoadjuvant therapy with temozolomide and 13-cis-retinoic acid in high grade glioma - a phase II-study

38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002.
Abstract No. 2090 (Clinical Study)

Jaeckle KA, Hess KR, Yung WK, Greenberg H, Fine H, Schiff D, Pollack IF, Kuhn J, Fink K, Mehta M, Cloughesy T, Nicholas MK, Chang S, Prados M; North American Brain Tumor Consortium
Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study
J Clin Oncol. 2003 Jun 15;21(12):2305-11 (Clinical Study, Abstract)


V. K. Puduvalli, W. K. A. Yung, M. Prados, J. Kuhn, K. Hess, M. Groves, V. Levin, S. Chang, J. Zwiebel, T. Cloughesy
Phase II trial of fenretinide in patients with recurrent malignant gliomas - A North American Brain Tumor Consortium study
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003.
Abstract No. 419 (Clinical Study)

Yung WK, Kyritsis AP, Gleason MJ, Levin VA
Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid
Clin Cancer Res 1996 Dec;2(12):1931-5 (Clinical Study, Abstract)



Medulloblastoma

Di C, Liao S, Adamson DC, Parrett TJ, Broderick DK, Shi Q, Lengauer C, Cummins JM, Velculescu VE, Fults DW, McLendon RE, Bigner DD, Yan H
Identification of OTX2 as a Medulloblastoma Oncogene Whose Product can be Targeted by All-Trans Retinoic Acid
Cancer Res. 2005 Feb 1;65(3):919-24. (Laboratory Investigation, Abstract+)


Meningioma

Puduvalli VK, Li JT, Chen L, McCutcheon IE
Induction of apoptosis in primary meningioma cultures by fenretinide
Cancer Res. 2005 Feb 15;65(4):1547-53. (Laboratory Investigation, Abstract)


Non-Nervous System Tumors

Zheng X, Chang RL, Cui XX, Kelly KA, Shih WJ, Lin Y, Strair R, Suh J, Han ZT, Rabson A, Conney AH
Synergistic effects of clinically achievable concentrations of 12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in HL-60 cells
Oncol Res 2000;12(9-10):419-27 (Cell Culture Study, Abstract)

Pili R, Kruszewski MP, Hager BW, Lantz J, Carducci MA
Combination of phenylbutyrate and 13-cis retinoic acid inhibits prostate tumor growth and angiogenesis
Cancer Res 2001 Feb 15;61(4):1477-85 (Cell Culture Study, Abstract & Full Text)

 

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