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Astrocytomas
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Chen B, Ahmed T, Mannancheril A, Gruber M, Benzil DL
Safety and efficacy of high-dose chemotherapy with autologous
stem cell transplantation for patients with malignant astrocytomas
Cancer. 2004 May 15;100(10):2201-7
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Atypical
teratoid/rhabdoid t.
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Gidwani P, Levy A, Goodrich J, Weidenheim K,
Kolb EA.
Successful outcome with tandem myeloablative chemotherapy and autologous
peripheral blood stem cell transplants in a patient with atypical teratoid/rhabdoid
tumor of the central nervous system
J Neurooncol.
2008 Jun;88(2):211-5.
Epub 2008 Mar 04
.JPG)
Abstract
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Basic
Science
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Li W, Sun W, Zhang Y, Wei W, Ambasudhan R, Xia P, Talantova M, Lin T, Kim J,
Wang X, Kim WR, Lipton SA, Zhang K, Ding S.
Rapid induction and long-term self-renewal of primitive neural precursors
from human embryonic stem cells by small molecule inhibitors.
Proc
Natl Acad Sci U S A. 2011 Apr 27. [Epub ahead of print]
Abstract |
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News
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Mimeault
M, Batra SK
Targeting of cancer stem/progenitor cells plus stem cell-based therapies:
the ultimate hope for treating and curing aggressive and recurrent cancers
Panminerva Med. 2008 Mar;50(1):3-18
Abstract
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Report on the Workshop "New Technologies
in Stem Cell Research," Society for Pediatric Research, San Francisco,
California, April 29, 2006. doi:10.1634/stemcells.2006-0397. First published online January 25, 2007
Abstract
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Ana I Teixeira, Joshua K Duckworth, Ola Hermanson
Getting the right stuff: Controlling neural stem cell
state and fate in vivo and in vitro with biomaterials
Cell Research 17,
56 - 61 ( Jan 2007). Published online 9 January 2007
Abstract
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Brain Tumors
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Aboody KS, Najbauer J, Danks MK
Stem and progenitor cell-mediated tumor selective gene therapy
Gene Ther. 2008 Mar 27; [Epub ahead of print]
Abstract
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Ahmed
AU, Alexiades NG, Lesniak MS.
The use of neural stem cells in cancer gene therapy: Predicting the path to
the clinic.
Curr Opin Mol Ther. 2010 Oct;12(5):546-52.
Abstract |
Related articles
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Frank
RT, Edmiston M, Kendall SE, Najbauer J, Cheung CW, Kassa T, Metz MZ, Kim SU,
Glackin CA, Wu AM, Yazaki PJ, Aboody KS
Neural
stem cells as a novel platform for tumor-specific delivery of therapeutic
antibodies
PLoS One. 2009
Dec 15;4(12):e8314
Abstract | .png)
Full text | .png)
Reprint
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Brown AB, Yang W, Schmidt NO, Carroll R, Leishear
KK, Rainov NG, Black PM, Breakefield XO, Aboody KS
Intravascular delivery of neural stem cell
lines to target intracranial and extracranial tumors of neural and
non-neural origin
Hum Gene Ther. 2003 Dec 10;14(18):1777-85
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Kim
SU
Neural Stem Cell-based Gene Therapy for Brain Tumors
Stem Cell Rev. 2010 Jun 3;. [Epub ahead of print]
Abstract
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Nicoletti
F, Arcella A, Iacovelli L, Battaglia G, Giangaspero F, Melchiorri D.
Metabotropic glutamate receptors: new targets for the control of tumor
growth?
Trends
Pharmacol Sci. 2007 Apr 10; [Epub ahead of print]
PMID: 17433452 [PubMed - as supplied by publisher]
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Mark Noble
Can neural stem cells be used to track down and destroy
migratory brain tumor cells while also providing a means of repairing
tumor-associated damage?
PNAS, November 7, 2000, vol. 97 no. 23, 12393-12395
Full
Text |
Reprint
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Monje
ML, Palmer T
Radiation
injury and neurogenesis
Curr
Opin Neurol. 2003 Apr;16(2):129-34
Abstract
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Shih CS, Hale GA, Gronewold L, Tong X, Laningham
FH, Gilger EA, Srivastava DK, Kun LE, Gajjar A, Fouladi M
High-dose chemotherapy with autologous stem cell rescue for children with
recurrent malignant brain tumors
Cancer. 2008 Jan 25; [Epub ahead of print]
Abstract
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Embryonal
Tumors
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Gill P, Litzow M, Buckner J, Arndt C, Moynihan
T, Christianson T, Ansell S, Galanis E.
High-dose chemotherapy with autologous stem cell transplantation in
adults with recurrent embryonal tumors of the central nervous system
Cancer. 2008 Feb 25; [Epub ahead of print]
Abstract
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Glioblastoma
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Ahmed AU, Lesniak MS.
Glioblastoma
multiforme: can neural stem cells deliver the therapeutic payload and
fulfill the clinical promise?
Expert Rev
Neurother. 2011 Jun;11(6):775-7.
Abstract |
Reprint |
Related articles
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Benedetti S, Pirola B, Pollo B, Magrassi L, Bruzzone MG, Rigamonti D,
Galli R, Selleri S, Di Meco F, De Fraja C, Vescovi A, Cattaneo E, Finocchiaro G
Gene
therapy of experimental brain tumors using neural progenitor cells
Nat
Med. 2000 Apr;6(4):447-50
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Ehtesham
M, Kabos P, Gutierrez MA, Chung
NH, Griffith TS, Black KL, Yu JS
Induction
of glioblastoma apoptosis using neural stem cell-mediated delivery of
tumor necrosis factor-related apoptosis-inducing ligand
Cancer Res 2002 Dec
15;62(24):7170-4
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Germano IM, Uzzaman M, Keller G.
Gene delivery by embryonic stem cells for malignant glioma therapy: Hype
or hope?
Cancer Biol Ther. 2008 Sep 11;7(9). [Epub ahead of print]
Abstract
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Martin R. Graf,
Martin R. Jadus, John C.
Hiserodt, H. Terry Wepsic and Gale A. Granger
Development of Systemic Immunity to Glioblastoma Multiforme Using Tumor
Cells Genetically Engineered to Express the Membrane-Associated Isoform of
Macrophage Colony-Stimulating Factor
The Journal of Immunology, November 15 1999, Volume 163, No. 10,
5544-5551
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James D, Cavenee W.
Stem Cells for Treating Glioblastoma: How Close to Reality?
Neuro Oncol. 2009 Feb 23; [Epub ahead of print]
Abstract
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C.
Linassier, M. Ben Hassel, D. Figarella-Branger, J.-O. Bay, H.
Bourgeois, T. Lesimple, J.-P. Cottier, L. Taillandier, R. Delepine, D.
Frappaz
Phase
III study comparing high-dose BCNU with autologous blood stem cell support
versus standard dose BCNU, in combination with radiotherapy after gross
total resection in patients with supratentorial glioblastoma
39th ASCO Annual
Meeting. Chicago, IL. May 31-June 3, 2003.
Abstract No. 399
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Lorico
A, Mercapide J, Soloduschko V, Alexeyev M, Fodstad O, Rappa G.
Primary neural stem/progenitor cells expressing endostatin or cytochrome
P450 for gene therapy of glioblastoma
Cancer Gene Ther. 2008 Apr 18; [Epub ahead of print]
Abstract
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Aurelio
Lorico, Victor Solodushko, Oystein Fodstad, Germana Rappa
Gene-engineered
primary neural stem/progenitor cells for treatment of malignant brain
tumors
96th AACR Annual Meeting, Anaheim/Orange County, CA, April
16-20, 2005
Proc Amer Assoc Cancer Res
2005;46:Abstract
No.2064
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Rath
P, Shi H, Maruniak JA, Litofsky NS, Maria CNO, Kirk MD
Stem cells as vectors to deliver HSV/tk gene therapy for malignant gliomas
Curr Stem Cell Res Ther. 2009 Jan;4(1):44-9
Abstract
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Mesenchymal Stem Cells
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Bak XY, Dang HL, Yang J, Ye K, Lee EX, Lim SK, Wang S.
Human Embryonic Stem Cell-derived Mesenchymal Stem Cells as Cellular
Delivery Vehicles for Prodrug Gene Therapy of Glioblastoma.
Hum Gene Ther. 2011 Mar 22;. [Epub ahead of print]
Abstract |
Reprint |
Related articles
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Yin
J, Kim JK, Moon JH, Beck S, Piao D, Jin X, Kim SH, Lim YC, Nam DH, You S,
Kim H, Choi YJ.
hMSC-mediated Concurrent Delivery of Endostatin and Carboxylesterase to
Mouse Xenografts Suppresses Glioma Initiation and Recurrence.
Mol Ther. 2011 Mar 8;. [Epub ahead of print]
Abstract |
Related articles
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Retinoic
acid
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Ying
M, Wang S, Sang Y, Sun P, Lal B, Goodwin CR, Guerrero-Cazares H,
Quinones-Hinojosa A, Laterra J, Xia S.
Regulation of glioblastoma stem cells by retinoic acid: role for Notch
pathway inhibition.
Oncogene. 2011 Mar 7;. [Epub ahead of print]
Abstract |
Related articles
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Gliomas
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Eskandary H, Basiri M, Nematollahi-Mahani SN, Mehravaran S.
The
role of stem cells in tumor targeting and growth suppression of gliomas.
Biologics.
2011;5:61-70. Epub 2011 Apr 5.
Abstract |
Reprint |
Related articles
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Karen
S. Aboody,
Alice Brown,
Nikolai G. Rainov,
Kate A. Bower, Shaoxiong Liu, Wendy Yang,
Juan E. Small, Ulrich Herrlinger,
Vaclav Ourednik, Peter McL. Black, Xandra O.
Breakefield,
and Evan Y. Snyder
Neural stem cells
display extensive tropism for pathology in adult brain: Evidence from
intracranial gliomas
PNAS,
November 7, 2000, vol. 97, no. 23, 12846-12851
Abstract |
Full text |
Reprint
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Vincenza
Barresi, Natale Belluardo, Simonetta Sipione, Giuseppa Mudò, Elena
Cattaneo and Daniele Filippo Condorelli
Transplantation of prodrug-converting
neural progenitor cells for brain tumor therapy
Cancer Gene Ther, May 1, 2003; 10(5): 396-402
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Capper D, Gaiser T, Hartmann C, Habel A, Mueller
W, Herold-Mende C, von Deimling A, Siegelin MD
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit
down-regulation of caspase-8 by promoter methylation
Acta Neuropathol. 2009 Feb 12; [Epub ahead of print]
Abstract |
Full text |
Reprint
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Ehtesham
M, Kabos P, Kabosova A, Neuman T, Black KL, Yu JS
The use
of interleukin 12-secreting neural stem cells for the treatment of
intracranial glioma
Cancer Res 2002 Oct
15;62(20):5657-63
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Frosina
G.
Stem Cell-Mediated Delivery of
Therapies in the Treatment of Glioma.
Mini Rev Med Chem. 2011 May
16;. [Epub ahead of print]
Abstract |
Related articles
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Herrlinger U,
Woiciechowski C, Sena-Esteves M, Aboody KS, Jacobs AH, Rainov NG, Snyder
EY, Breakefield XO
Neural precursor cells for delivery of
replication-conditional HSV-1 vectors to intracerebral gliomas
Mol Ther. 2000 Apr;1(4):347-57
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Jinwei Hu, Xiangpeng Yuan,
Maria L. Belladonna, John M. Ong, Sebastian
Wachsmann-Hogiu, Daniel L. Farkas, Keith L. Black
and John S. Yu
Induction of Potent Antitumor Immunity by Intratumoral Injection of
Interleukin 23–Transduced Dendritic Cells
Cancer Research 66, 8887-8896, September 1, 2006
Abstract
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Text |
Reprint
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News
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Shaoyi
Li, Yun Gao, Tsutomu Tokuyama,
Junkoh Yamamoto, Naoki Yokota, Seiji Yamamoto, Susumu Terakawa, Masatoshi
Kitagawa and Hiroki Namba
Genetically engineered neural
stem cells migrate and suppress glioma cell growth at distant intracranial
sites
Cancer Lett. 2006 Dec 28; [Epub ahead of
print]
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Shaoyi
Li, Tsutomu Tokuyama, Junkoh Yamamoto, Masayo Koide, Naoki Yokota,
Hiroki Namba
Potent Bystander Effect in
Suicide Gene Therapy Using Neural Stem Cells Transduced with Herpes
Simplex Virus Thymidine Kinase Gene
Oncology. 2005;69(6):503-8. Epub 2006 Jan 16
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Gentao Liu, Keith L
Black and John S Yu
Sensitization of malignant glioma to
chemotherapy through dendritic cell vaccination
Expert Review of Vaccines, Apr 2006, Vol. 5, No. 2, Pages 233-247
Abstract
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Jiao H, Guan F, Yang B, Li J, Shan H, Song L, Hu X, Du Y.
Human umbilical cord blood-derived mesenchymal stem cells inhibit C6 glioma
via downregulation of cyclin D1.
Neurol India 2011;59:241-247. Epub 2011 Apr 7.
Abstract |
Full
text
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K
Nakamura, Y Ito, Y Kawano, K Kurozumi, M Kobune, H Tsuda, A Bizen, O
Honmou, Y Niitsu and H Hamada
Antitumor effect of genetically engineered
mesenchymal stem cells in a rat glioma model
Gene Ther, July 1, 2004; 11(14): 1155-64
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Roger
M, Clavreul A, Venier-Julienne MC, Passirani C, Sindji L, Schiller P,
Montero-Menei C, Menei P
Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to
brain tumors
Biomaterials. 2010 Aug 3;. [Epub ahead of print]
Abstract
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Shankar SK.
Human umbilical cord blood-derived mesenchymal stem cells and their effect
on gliomas.
Neurol India 2011;59:226-8. Epub 2011 Apr 7.
Abstract |
Full
text
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Christian
Schichor, Nima Etminan, Sabine Miebach, Jörg-Christian Tonn, Tobias
Birnbaum, Claudio Padovan, Roland Goldbrunner
Adult
human mesenchymal stem cells: VEGF-driven interaction with glioma cells in
vitro
96th AACR Annual Meeting, Anaheim/Orange County, CA, April
16-20, 2005
Proc Amer Assoc Cancer Res
2005;46:Abstract
No.2063
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Adam M. Sonabend, Ilya V. Ulasov, Matthew A.
Tyler, Angel A. Rivera, James M. Mathis, Maciej S. Lesniak
Mesenchymal Stem Cells Effectively Deliver an Oncolytic Adenovirus
to Intracranial Glioma
Stem Cells First published online January 10, 2008;
doi:doi:10.1634/stemcells.2007-0758
Abstract
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Yang
B, Wu X, Mao Y, Bao W, Gao L, Zhou P, Xie R, Zhou L, Zhu J
Dual-targeted antitumor effects against brainstem glioma by intravenous
delivery of tumor necrosis factor-related, apoptosis-inducing,
ligand-engineered human mesenchymal stem cells
Neurosurgery. 2009
Sep;65(3):610-24
Abstract
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Xiang-Peng Yuan, Jinwei Hu, Gentao Liu, Zhaohui
Zheng, Patrizia Tunici, Yasuharu Akasaki, Takayuki Yoshimoto, Keith L.
Black, and John S. Yu
Neural stem cell can mediate immune therapy for brain tumor
AACR Meeting Abstracts, Apr 2006; 2006: 241
Abstract
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Xiangpeng Yuan, Jinwei Hu,
Maria L. Belladonna, Keith L. Black and John
S. Yu
Interleukin-23–Expressing Bone Marrow–Derived Neural Stem-Like
Cells Exhibit Antitumor Activity against Intracranial Glioma
Cancer Research 66, 2630-2638, March 1, 2006
Abstract
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Text |
Reprint
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News
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Zhao
D, Najbauer J, Garcia E, Metz MZ, Gutova M, Glackin CA, Kim SU, Aboody KS
Neural
stem cell tropism to glioma: critical role of tumor hypoxia
Mol Cancer Res. 2008 Dec;6(12):1819-29
Abstract |
Full text |
Reprint
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Ziu
M, Schmidt NO, Cargioli TG, Aboody KS, Black PM, Carroll RS
Glioma-produced
extracellular matrix influences brain tumor tropism of human neural stem
cells
J
Neurooncol. 2006 Sep;79(2):125-33. Epub 2006 Apr 6
Abstract |
Reprint
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Gliomas
(High-Grade) |
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Aboody
KS
Neural stem cell-mediated cancer therapy: towards glioma clinical
trials
The
18th International Conference on Brain Tumor Research and Therapy
18th-20th May 2010, Travemünde, Germany
Abstract |
Reprint
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Ehtesham
M, Stevenson CB, Thompson
RC
Stem cell therapies for
malignant glioma
Neurosurgical Focus, Volume 19, September 2005
Abstract
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Reprint
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Frosina G.
Stem
cell-mediated delivery of therapies in the treatment of glioma.
Mini Rev Med
Chem. 2011 Jun 1;11(7):591-8.
Abstract |
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data |
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Germano
IM, Emdad L, Qadeer ZA, Binello E, Uzzaman M.
Embryonic stem cell (ESC)-mediated transgene delivery induces growth
suppression, apoptosis and radiosensitization, and overcomes temozolomide
resistance in malignant gliomas
Cancer Gene Ther. 2010 Jun 4;. [Epub ahead of print]
Abstract
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Kang SG, Jeun SS, Lim JY, Kim SM, Yang YS, Oh WI, Huh
PW, Park CK.
Cytotoxicity of human umbilical cord blood-derived
mesenchymal stem cells against human malignant glioma cells.
Childs
Nerv Syst. 2007 Oct 30; [Epub ahead of print]
Full
Text |
Reprint
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Folkins
C, Man S, Xu P, Shaked Y, Hicklin DJ, Kerbel RS.
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic
effects reduce the tumor stem-like cell fraction in glioma xenograft tumors.
Cancer Res. 2007 Apr
15;67(8):3560-4.
PMID: 17440065 [PubMed - in process]
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Le
S
FDA allows City of Hope to proceed with the first human neural
stem cell clinical trial to treat brain tumors
sle@coh.org 2010
June 2
News
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Li
SC, Han YP, Dethlefs BA, Loudon WG
Therapeutic Window, a Critical Developmental Stage for Stem Cell
Therapies
Curr Stem Cell Res Ther. 2010 Jun 9;. [Epub ahead of print]
Abstract
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Namba
H.
Glioma treatment strategies using mesenchymal stem cells.
Brain Nerve. 2010 Oct;62(10):1075-82.
Abstract |
Related articles
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Oh MC, Lim DA
Novel treatment strategies for malignant gliomas using neural stem cells
Neurotherapeutics. 2009 Jul;6(3):458-64
Abstract |
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Reprint
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Recurrent
Tumors
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Binello
E, Germano IM.
Stem cells as therapeutic
vehicles for the treatment of high-grade gliomas.
Neuro Oncol. 2011 Dec 13;. [Epub
ahead of print]
Abstract |
Related articles
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Malignant
Lymphoma
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P.
Colombat, T. Lamy, A. Lemevel, V. Delwail, M. Gardembas, A. Brion, C.
Berthou, J.-O. Bay, R. Delepine, C. Linassier
Phase II trial of high-dose chemotherapy with
autologous stem cell transplantation in first-line therapy of primary
central nervous system (CNS) lymphoma
39th ASCO Annual Meeting.
Chicago, IL. May 31-June 3, 2003. Abstract No.
400
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Medulloblastoma
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Sanchez-Diaz PC, Burton TL, Burns SC, Hung JY,
Penalva LO.
Musashi1 modulates cell proliferation genes in the medulloblastoma cell
line Daoy
BMC Cancer. 2008 Sep 30;8(1):280.
[Epub ahead of print]
Abstract |
Reprint
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Kim
SK, Kim SU, Park IH, Bang JH, Aboody KS, Wang KC, Cho BK, Kim M, Menon LG,
Black PM, Carroll RS
Human
neural stem cells target experimental intracranial medulloblastoma and
deliver a therapeutic gene leading to tumor regression
Clin Cancer
Res. 2006 Sep 15;12(18):5550-6
Abstract |
Full text |
Reprint
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Antonio Pérez-Martínez,
Alvaro Lassaletta, Marta González-Vicent, Julián Sevilla,
Miguel Angel Díaz and Luis Madero
High-dose chemotherapy with autologous
stem cell rescue for children with high risk and recurrent
medulloblastoma and supratentorial primitive neuroectodermal tumors
J Neurooncol.
71(1):
33-38, January 2005. (Abstract+)
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Antonio
Pérez-Martínez, Victor Quintero, Marta González Vicent, Julián
Sevilla, Miguel Ángel Díaz and Luis Madero
High-dose chemotherapy with autologous
stem cell rescue as first line of treatment in young children with
medulloblastoma and supratentorial primitive neuroectodermal tumors
J Neurooncol. 2004 Mar-Apr;67(1-2):101-6. (Abstract+)
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Metastatic Tumors
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Aboody
KS, Najbauer J, Schmidt NO, Yang W, Wu JK, Zhuge Y, Przylecki W, Carroll R,
Black PM, Perides G
Targeting
of melanoma brain metastases using engineered neural stem/progenitor cells
Neuro Oncol.
2006 Apr;8(2):119-26. Epub 2006 Mar 8
Abstract |
Full text |
Reprint
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G.
Brandon Gunn, Ruben D. Villa, Ross R. Sedler, Fred Hardwicke, Gianluigi
A. Fornari, Rufus J. Mark
Nasopharyngeal
Carcinoma Metastasis to the Pituitary Gland: A Case Report and Literature
Review
Journal of Neuro-Oncology, 68 (1): 87-90, May 2004. (Abstract+)
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Neural
Stem Cells
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Karen S. Aboody, Rebecca A. Bush, Elizabeth Garcia,
Marianne Z. Metz, Joseph Najbauer, Kristine A. Justus, Doris A. Phelps, Joanna S.
Remack, Karina Jin Yoon, Shanna Gillespie, Seung U. Kim, Carlotta A. Glackin,
Philip M. Potter, Mary K. Danks
Development of a Tumor-Selective Approach to Treat Metastatic
Cancer
PLoS ONE 1(1): e23; doi:10.1371/journal.pone.0000023; Published: December 20,
2006
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Cattaneo
E
Shc signalling in neural stem cells
Proc. Int. Symp. “New
Treatments for Brain Tumors: Gene Therapy and Neural Stem Cells”. Parma,
Italy, October 17-20, 2001. Abstract No. IS-2
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Riccardo Fodde
Stem
Cells and Metastatic Cancer: Fatal Attraction?
PLoS Medicine
Vol. 3, No. 12, e482; doi:10.1371/journal.pmed.0030482; Published: December 26,
2006
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Neuronal-Glial Tumors
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Amariglio N, Hirshberg A, Scheithauer BW, Cohen
Y, Loewenthal R, Trakhtenbrot L, Paz N, Koren-Michowitz M, Waldman D,
Leider-Trejo L, Toren A, Constantini S, Rechavi G
Donor-derived brain tumor following neural stem cell transplantation in
an ataxia telangiectasia patient
PLoS Med. 2009 Feb 17;6(2):e1000029
Abstract |
Full text |
Reprint
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Pediatric
Patients
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Maura
Massimino,
Lorenza Gandola, Roberto Luksch, Filippo Spreafico, Daria Riva, Carlo
Solero, Felice Giangaspero, Franco Locatelli, Marta Podda, Fabio
Bozzi, Emanuele Pignoli, Paola Collini, Graziella Cefalo, Marco Zecca,
Michela Casanova, Andrea Ferrari, Monica Terenziani, Cristina Meazza,
Daniela Polastri, Davide Scaramuzza, Fernando Ravagnani, and Franca
Fossati-Bellani
Sequential chemotherapy, high-dose
thiotepa, circulating progenitor cell rescue, and radiotherapy for
childhood high-grade glioma
Neuro-Oncology, Volume
7, Number 1, Pages 41 -- 48, January 2005. (Abstract+)
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Primary
CNS Lymphoma
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Illerhaus G, Marks R, Ihorst G, Guttenberger R,
Ostertag
C, Derigs G, Frickhofen N, Feuerhake F, Volk B, Finke J.
High-dose chemotherapy with autologous
stem-cell transplantation and hyperfractionated radiotherapy as first-line
treatment of primary CNS lymphoma.
J
Clin Oncol. 2006 Aug
20;24(24):3865-70. Epub 2006 Jul 24.
Abstract
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