Treatment > STI571 (Gleevec, Imatinib)


Glioblastoma


G. Dresemann
Imatinib (STI 571)/ plus hydroxyurea: Safety and efficacy in pre-treated, progressive Glioblastoma Multiforme (GBM) patients (pts): An update on the initial 30 pts
2005 ASCO Annual Meeting. Orlando, FL. May 13-17. Abstract No. 1516. (Clinical Study)
Journal of Clinical Oncology, Vol 23, No 16S (June 1 Supplement), 2005: 1516


G. Dresemann
Imatinib (STI571) plus hydroxyurea: Safety and efficacy in pre-treated, progressive glioblastoma multiforme (GBM) patients (pts)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1550 (Clinical Study)

G. Dresemann
STI 571/hydroxyurea in progressive, pretreated glioblastoma (GB) patients (pts.)
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 465 (Clinical Study)

Gregor Dresemann
CD 117 (c-kit) - predictive for efficacy of imatinib in pretreated glioblastoma patients?
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No.
2082 (Clinical Study)

M. Holdhoff, K. A. Kreuzer, C. Appelt, R. Scholz, A. Jordan, B. Hildebrandt, C. A. Schmidt, R. A. Van Etten, B. Dörken, P. Le Coutre
Combined administration of imatinib mesylate and ionizing radiation leads to increased radiosensitivity in the human glioblastoma cell line RuSi RS1
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1564 (Cell Culture Study)

Kilic T, Alberta JA, Zdunek PR, Acar M, Iannarelli P, O'Reilly T, Buchdunger E, Black PM, Stiles CD
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
Cancer Res 2000 Sep 15;60(18):5143-50 (Animal Study, Abstract & Full Text)

E. Raymond, A. Brandes, A. Van Oosterom, C. Dittrich, P. Fumoleau, B. Coudert, C. Twelves, C. De Balincourt, D. Lacombe, M. Van Den Bent
Multicentre phase II study of imatinib mesylate in patients with recurrent glioblastoma: An EORTC: NDDG/BTG Intergroup Study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1501 (Clinical Study)

Huan Ren, Alf Giese, Tingchang Chou, Steven Pelech, Nikolai Rainov
Biological activity of a novel tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class, Imatinib (STI571, Gleevec), on human glioblastoma cells
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract No. R3776 (Cell Culture Study)

Patrick Y Wen, W K Yung, Kenneth Hess, Sandra Silberman, Michael Hayes, David Schiff, Frank Lieberman, Timothy F Cloughesy, Lisa M DeAngelis, Susan M Chang, Larry Junck, Howard A Fine, Karen Fink, H I Robins, Jeffrey J Raizer, Lauren E Abrey, Minesh P Mehta, Elizabeth A Maher, Peter M Black, John Kuhn, Renaud Capdeville, Richard S Kaplan, Anthony Murgo, Charles Stiles, Michael D Prados
Phase I study of STI571 (Gleevec) for patients with recurrent malignant gliomas and meningiomas (NABTC 99-08)
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No. 288 (Clinical Study)


Gliomas


M. van den Bent, A. Brandes, M. Frenay, P. Fumoleau, R. Stupp, C. Dittrich, B. Coudert, P. Clement, D. Lacombe and E. Raymond
Multicentre phase II study of imatinib mesylate in patients with recurrent anaplastic oligodendroglioma (AOD)/mixed oligoastrocytoma (MOA) and anaplastic astrocytoma (AA)/low grade astrocytoma (LGA): An EORTC New Drug Development Group (NDDG) and Brain Tumor Group (BTG) study
2005 ASCO Annual Meeting. Orlando, FL. May 13-17. Abstract No. 1517. (Clinical Study)
Journal of Clinical Oncology, Vol 23, No 16S (June 1 Supplement), 2005: 1517


H. S. Friedman, J. Quinn, J. Rich, J. Vredenburgh, A. Desjardins, S. Sathornsumetee, A. Salvado, Z. Nikolova, D. Bigner and D. Reardon
Efficacy of imatinib mesylate plus hydroxyurea regimen in the treatment of recurrent malignant glioma: Phase II study results
2005 ASCO Annual Meeting. Orlando, FL. May 13-17. Abstract No. 1515. (Clinical Study)
Journal of Clinical Oncology, Vol 23, No 16S (June 1 Supplement), 2005: 1515


A. Katz, C. H. Barrios, R. Abramoff, S. D. Simon, J. Tabacof, R. C. Gansl 
Imatinib (STI 571) is active in patients (PTS) with high-grade gliomas progressing on standard therapy
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1542 (Clinical Study)

Landonio Giuseppe, Riva Maurizio, Galli Carlo, Schiavo Roberta, Carminati Ornella, Secondino Simona, Gambacorta Marcello, Defanti Carlo Alberto, Siena Salvatore
Overexpression of c-kit oncogene in human brain tumors
38th ASCO Annual Meeting. Orlando, FL. May 18-21, 2002. Abstract No. 295 (Cell Culture Study)

Reardon DA, Desjardins A, Vredenburgh JJ, Sathornsumetee S, Rich JN, Quinn JA, Lagattuta TF, Egorin MJ, Gururangan S, McLendon R, Herndon Ii JE, Friedman AH, Salvado AJ, Friedman HS.
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: Phase 1 trial in adults with malignant glioma
Neuro Oncol. 2008 Mar 21; [Epub ahead of print]
 Abstract |
DBLinks | BL 7:7

F. S. Viola, F. Morrone, J. Stella, F. Spiller, A. Battastini, C. H. Barrios
Combination of STI571 and temozolamide on inhibition of rat and human glioma cell lines proliferation
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 469 (Cell Culture Study)


Medulloblastoma


R. Morosetti, D. Meco, C. Dominici, T. Servidei, A. Riccardi, A. M. Di Francesco, G. Cusano, R. Riccardi
Antitumor activity of imatinib mesylate in medulloblastoma cell lines and xenografts
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.8554 (Animal Study)

 

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