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Brain
Tumors
|
|
|
|
Stupp
R, Gander M, Leyvraz S, Newlands E
Current
and future developments in the use of temozolomide for the treatment of
brain tumours
Lancet Oncol. 2001 Sep; 2(9): 552-60.
|
|
|
Cancer
Research
|
|
|
|
Pegg
AE
Mammalian
O6-alkylguanine-DNA alkyltransferase: regulation and importance in
response to alkylating carcinogenic and therapeutic agents
Cancer Res 1990 Oct 1;50(19):6119-29
|
|
|
Shinoura N, Yamada R, Tabei Y, Saito K, Nakamura
O, Takahashi M.
Temozolomide-temodal
Gan To Kagaku Ryoho. 2008 Mar;35(3):543-7
Abstract |
DBLinks | BL 7:7
|
|
|
Glioblastoma
|
|
|
|
Manish Aghi, Samuel Rabkin,
Robert L. Martuza
Effect of Chemotherapy-Induced DNA Repair on
Oncolytic Herpes Simplex Viral Replication
Journal of the National Cancer Institute, Vol. 98, No. 1, 38-50, January 4, 2006
Abstract
| BrainLife
|
News
|
|
Balana C,
Ramirez JL, Taron M, Roussos Y, Ariza A, Ballester R, Sarries C, Mendez P,
Sanchez JJ, Rosell R
O(6)-methyl-guanine-DNA
methyltransferase Methylation in Serum and Tumor DNA Predicts Response to
1,3-Bis(2-Chloroethyl)-1-Nitrosourea but not to Temozolamide Plus
Cisplatin in Glioblastoma Multiforme
Clin Cancer Res
2003 Apr;9(4):1461-8
|
|
Susan E. Jones-Bolin, Hugh
Zhao, Kathryn Hunter, Bruce Ruggeri
Effects of
chronic oral administration of the pan VEGF-R kinase inhibitor,
CEP-7055, alone and in combination with temozolomide (TMZ), on
primary tumor growth, neurological dysfunction, and survival in
an orthotopic model of human glioblastoma in nude mice
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract
No. 61
|
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Arabinda Das, Kunal D. Patel, Marc S. Weinberg, Sunil J.
Patel, Naren L. Banik, Swapan K. Ray
Modulatory effect of dexamethasone on temozolomide induced
apoptosis in human glioblastoma U87MG cells
Proceedings of the AACR, Volume 45, March 2004, Abstract
Number: 554.
|
|
Huan Ren, Alf Giese,
Tingchang Chou, Steven Pelech, Nikolai Rainov
Biological
activity of a novel tyrosine kinase inhibitor of the
2-phenylaminopyrimidine class, Imatinib (STI571, Gleevec), on
human glioblastoma cells
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract
No. R3776
|
|
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Antonio Silvani, Elena Lamperti, Paola Gaviani,
Marica Eoli, Anna Fiumani, Andrea Salmaggi, Chiara Falcone,
Graziella Filippini, Andrea Botturi and Amerigo Boiardi
Salvage chemotherapy with procarbazine and fotemustine combination in the
treatment of temozolomide treated recurrent glioblastoma patients
Journal of Neuro-Oncology, Epub June 19, 2007, DOI:
10.1007/s11060-007-9427-y
Abstract |
DBLinks | BL 7:4
|
|
|
van
Nifterik KA, van den Berg J, Stalpers LJ, Lafleur MV, Leenstra S, Slotman BJ,
Hulsebos TJ, Sminia P.
Differential Radiosensitizing Potential of
Temozolomide in MGMT Promoter Methylated Glioblastoma Multiforme Cell Lines.
Int
J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1246-53.
Abstract
|
|
|
Gliomas
|
|
|
|
Marco Balzarotti, Emilio Ciusani, Chiara Calatozzolo, Danilo Croci,
Amerigo Boiardi, and Andrea Salmaggi
Effect of Association of Temozolomide With Other
Chemotherapic Agents on Cell Growth Inhibition in Glioma Cell Lines
Oncology Research, 2004, Volume 14, pp. 325-330.
|
|
|
Dora
B. Bocangel, Sydney Finkelstein, S. Clifford Schold, Kishor K. Bhakat, Sankar
Mitra and Demetrius M. Kokkinakis
Multifaceted Resistance of Gliomas to Temozolomide
Clinical Cancer Research Vol. 8, 2725-2734, 1 August 2002
Abstract |
Full Text |
Reprint |
DBLinks | BL
1:3
|
|
M.J.M.
Darkes, G.L. Plosker, B. Jarvis
Temozolomide: A Review of its Use in the
Treatment of Malignant Gliomas, Malignant Melanoma and Other Advanced
Cancers
American Journal of Cancer,
Volume 1, Number 1, Pages: 55 -- 80 [2002]
|
|
Dinnes
J, Cave C, Huang S, Milne R
A rapid
and systematic review of the effectiveness of temozolomide for the
treatment of recurrent malignant glioma
Br J Cancer. 2002 Feb 12;86(4):501-5
|
|
Friedman HS, Keir S, Pegg AE, Houghton PJ, Colvin OM, Moschel RC,
Bigner DD, Dolan ME
O6-benzylguanine-mediated
enhancement of chemotherapy
Mol Cancer Ther 2002
Sep;1(11):943-8
|
|
Takao Kanzawa, Hideaki Ito, Yasuko Kondo, Seiji Kondo
Role of autophagy in temozolomide-induced cytotoxicity for
malignant glioma cells
Proceedings of the AACR, Volume 45, March 2004, Abstract
Number: 579.
|
|
Kanzawa T,
Germano IM, Kondo Y, Ito H, Kyo S, Kondo S
Inhibition
of telomerase activity in malignant glioma cells correlates with their
sensitivity to temozolomide
Br J Cancer.
2003 Sep 1;89(5):922-929 (Cell Culture Study, Abstract)
|
|
Murphy PS, Viviers L, Abson C, Rowland IJ, Brada M, Leach
MO, Dzik-Jurasz AS
Monitoring temozolomide treatment of low-grade glioma
with proton magnetic resonance spectroscopy
Br J Cancer. 2004 Feb 23;90(4):781-6.
|
|
Panetta
JC, Kirstein MN, Gajjar AJ, Nair G, Fouladi M, Stewart CF
A
mechanistic mathematical model of temozolomide myelosuppression in children with
high-grade gliomas
Math
Biosci. 2003 Nov;186(1):29-41
|
| |
Susan
Pannullo, D. C
Shungu, R. L DeLaPaz, M. Odaimi, J. Serventi, L. Heller, C. M Balmaceda
Use
of magnetic resonance spectroscopy (MRS) in malignant gliomas treated with
temozolomide (TMZ)
38th
ASCO Annual Meeting. Orlando, FL. May 18-21, 2002.
Abstract No.
2101.
|
|
Patel
VJ, Elion GB, Houghton PJ, Keir S, Pegg AE, Johnson SP, Dolan ME,
Bigner DD, Friedman HS
Schedule-dependent
activity of temozolomide plus CPT-11 against a human central nervous
system tumor-derived xenograft
Clin Cancer Res 2000
Oct;6(10):4154-7
|
|
Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L,
Garcia-Lopez JL, Piquer J, Safont MJ, Balana C, Sanchez-Cespedes M,
Garcia-Villanueva M, Arribas L, Esteller M
CpG island hypermethylation of the DNA repair enzyme
methyltransferase predicts response to temozolomide in primary gliomas
Clin Cancer Res. 2004 Aug 1;10(15):4933-8.
|
|
Plowman
J, Waud WR, Koutsoukos AD, Rubinstein LV, Moore TD, Grever MR
Preclinical
antitumor activity of temozolomide in mice: efficacy against human brain tumor
xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea
Cancer
Res 1994 Jul 15;54(14):3793-9
|
|
Lucio Tentori, Carlo
Leonetti, Marco Scarsella, Giulia d'Amati, Weizheng Xu, Vincent
Kalish, Jie Zhang, Gabriella Zupi, Grazia Graziani
Systemic
administration of the PARP inhibitor GPI 15427 increases the
anti-tumor activity of temozolomide in melanoma, glioma and
lymphoma preclinical models in vivo
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract
No. 5466
|
|
van
Rijn J, Heimans JJ, van den Berg J, van der Valk P, Slotman BJ
Survival
of human glioma cells treated with various combination of temozolomide and
X-rays
Int J Radiat Oncol Biol Phys. 2000 Jun 1; 47(3): 779-84
|
|
Meg Verrees, Lili Liu, Stanton L. Gerson
Interruption of base excision repair selectively enhances
temozolamide and 1,3-bis(2-chloroethyl)-nitrosurea cytotoxicity in treatment of
adult human malignant glioma cell lines
Proceedings of the AACR, Volume 45, March 2004, Abstract
Number: 1548.
|
|
F.
S. Viola, F. Morrone, J. Stella, F. Spiller, A. Battastini, C. H. Barrios
Combination
of STI571 and temozolamide on inhibition of rat and human glioma cell lines
proliferation
39th
ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 469
|
|
|
Yamini B, Yu X, Pytel P, Galanopoulos N, Rawlani
V, Veerapong J, Bickenbach K, Weichselbaum RR
Adenovirally delivered tumor necrosis
factor-alpha improves the antiglioma efficacy of concomitant radiation and
temozolomide therapy
Clin
Cancer Res. 2007 Oct 15;13(20):6217-23
Abstract |
DBLinks | BL 7:2
|
|
|
Hum.
lymphoblastoid cell lines
|
|
|
|
D'Atri S, Tentori L, Lacal PM,
Graziani G, Pagani E, Benincasa E, Zambruno G, Bonmassar E, Jiricny J
Involvement
of the mismatch repair system in temozolomide-induced apoptosis
Mol Pharmacol 1998 Aug;54(2):334-41 (PDF Full Text)
|
|
|
Metastatic Tumors
|
|
|
|
Islam
R, Isaacson BJ, Zickerman PM, Ratanawong C, Tipping SJ
Hemorrhagic
cystitis as an unexpected adverse reaction to temozolomide: case report
Am J Clin Oncol 2002
Oct;25(5):513-4
|
|
Lucio Tentori, Carlo Leonetti, Marco Scarsella, Weizheng Xu,
David C. Calvin, Lisa Morgan, Zhaocheng Tang, Krystyna M. Wozniak, Christina
Alemu, Randall Hoover, Rena G. Lapidus, Gabriella Zupi, Jie Zhang, Grazia
Graziani
Oral administration of the PARP-1 inhibitor GPI 15427 increases
the anti-tumor activity of temozolomide against melanoma growing at the CNS site
Proceedings of the AACR, Volume 45, March 2004, Abstract
Number: 2007.
|
|
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Anaplastic
Oligoastrocytoma
|
|
|
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Alfredo D. Voloschin,
David N. Louis, Garth R. Cosgrove, and Tracy T. Batchelor
Neoadjuvant temozolomide followed by complete resection of a 1p- and
19q-deleted anaplastic oligoastrocytoma: Case study
Neuro-Oncology, Volume
7, Number 1, Pages 97 -- 100, January 2005. (Abstract+)
|
|
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Pediatric
Brain Tumors
|
|
|
|
Michael S. Bobola, Richard Ellenbogen, Ryan Goff, John Silber
Ablation of O6-methylguanine-DNA methyltransferase
with O6-benzylguanine reduces the resistance of pediatric primary
brain tumor cell lines to temozolomide and BCNU
Proceedings of the AACR, Volume 45, March 2004, Abstract
Number: 2143.
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