Current Neuro-Oncology

Volume 23 Number 18
30 September 2021

Home > Publications > Current Neuro-Oncology > Volume 23, Year 2021 > Number 18, 30 September

Morscher RJ, Brard C, Berlanga P, Marshall LV, André N, Rubino J, Aerts I, De Carli E, Corradini N, Nebchi S, Paoletti X, Mortimer P, Lacroix L, Pierron G, Schleiermacher G, Vassal G, Geoerger B.
First-in-child phase I/II study of the dual mTORC1/2 inhibitor vistusertib (AZD2014) as monotherapy and in combination with topotecan-temozolomide in children with advanced malignancies: arms E and F of the AcSé-ESMART trial.
Eur J Cancer. 2021 Sep 17, 2021;157:268-277∟. doi: 10.1016/j.ejca.2021.08.010∟. PMID: 34543871∟. Interventional study˰ ˍ

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Tomita Y, Tanaka Y, Takata N, Hibler EA, Hashizume R, Becher OJ.
Fifteen-year trends and differences in mortality rates across sex, age, and race/ethnicity in patients with brainstem tumors.
Neurooncol Adv. 2021 Sep 17, 2021;3(1):vdab137∟. doi: 10.1093/noajnl/vdab137∟. PMID: 34693287∟. Observational study. ˍ

Sun P, Fan DJ, Fan T, Li X, Qi XL, Zhao XG, Gai QF.
A Prospective Clinical Study on MGMT Protein Expression and the Effect of Gene Promoter Methylation on Sensitivity to Chemotherapeutics in Spinal Glioma.
J Inflamm Res. 2021 Sep 18, 2021;14:4777-4784∟. doi: 10.2147/JIR.S321790∟. PMID: 34566423∟. Interventional study. ˍ

Yamamuro S, Takahashi M, Satomi K, Sasaki N, Kobayashi T, Uchida E, Kawauchi D, Nakano T, Fujii T, Narita Y, Kondo A, Wada K, Yoshino A, Ichimura K, Tomiyama A.
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
Cancer Sci. 2021 Sep 18∟. doi: 10.1111/cas.15141∟. PMID: 34536314∟. Laboratory investigation. ˍ

de la Cruz L, Chen X, Konugoglu E, Ciernik IF.
Changes of healthy brain tissue after salvage radiotherapy of glioblastoma.
Neurooncol Adv. 2021 Sep 20, 2021;3(1):vdab139∟. doi: 10.1093/noajnl/vdab139∟. PMID: 34901856∟. Observational study. ˍ

Deng MY, Sturm D, Pfaff E, Sill M, Stichel D, Balasubramanian GP, Tippelt S, Kramm C, Donson AM, Green AL, Jones C, Schittenhelm J, Ebinger M, Schuhmann MU, Jones BC, van Tilburg CM, Wittmann A, Golanov A, Ryzhova M, Ecker J, Milde T, Witt O, Sahm F, Reuss D, Sumerauer D, Zamecnik J, Korshunov A, von Deimling A, Pfister SM, Jones DTW.
Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B.
Nat Commun. 2021 Sep 20, 2021;12(1):5530∟. doi: 10.1038/s41467-021-25708-y∟. PMID: 34545083∟. Laboratory investigation. ˍ

DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL.
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
Nat Commun. 2021 Sep 20, 2021;12(1):5531∟. doi: 10.1038/s41467-021-25709-x∟. PMID: 34545084∟. Laboratory investigation. ˍ

Giovagnoli AR, Meneses RF, Paterlini C, Silvani A, Boiardi A.
Cognitive awareness after treatment for high-grade glioma.
Clin Neurol Neurosurg. 2021 Sep 20, 2021;210:106953∟. doi: 10.1016/j.clineuro.2021.106953∟. PMID: 34607197∟. Observational study˰ ˍ

Kim KH, Yoo J, Kim N, Moon JH, Byun HK, Kang SG, Chang JH, Yoon HI, Suh CO.
Efficacy of Whole-Ventricular Radiotherapy in Patients Undergoing Maximal Tumor Resection for Glioblastomas Involving the Ventricle.
Front Oncol. 2021 Sep 21, 2021;11:736482∟. doi: 10.3389/fonc.2021.736482∟. PMID: 34621677∟. Observational study. ˍ

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Lombardi G, Caccese M, Padovan M, Cerretti G, Pintacuda G, Manara R, Di Sarra F, Zagonel V.
Regorafenib in Recurrent Glioblastoma Patients: A Large and Monocentric Real-Life Study.
Cancers (Basel). 2021 Sep 21, 2021;13(18):4731∟. doi: 10.3390/cancers13184731∟. PMID: 34572958∟. Observational study. ˍ

Varlet P, Bouffet E, Casanova M, Giangaspero F, Antonelli M, Hargrave D, Ladenstein R, Pearson A, Hawkins C, König FB, Rüschoff J, Schmauch C, Bühnemann C, Garin-Chesa P, Schweifer N, Uttenreuther-Fischer M, Gibson N, Ittrich C, Krämer N, Solca F, Stolze B, Geoerger B.
Comprehensive analysis of the ErbB receptor family in pediatric nervous system tumors and rhabdomyosarcoma.
Pediatr Blood Cancer. 2021 Sep 21, 2021:e29316∟. doi: 10.1002/pbc.29316∟. PMID: 34546642∟. Laboratory investigation. ˍ

Carvalho DM, Richardson PJ, Olaciregui N, Stankunaite R, Lavarino C, Molinari V, Corley EA, Smith DP, Ruddle R, Donovan A, Pal A, Raynaud FI, Temelso S, Mackay A, Overington JP, Phelan A, Sheppard D, Mackinnon A, Zebian B, Al-Sarraj S, Merve A, Pryce J, Grill J, Hubank M, Cruz O, Morales La Madrid A, Mueller S, Carcaboso AM, Carceller F, Jones C.
Repurposing vandetanib plus everolimus for the treatment of ACVR1-mutant diffuse intrinsic pontine glioma.
Cancer Discov. 2021 Sep 22, 2021:candisc.1201.2020∟. doi: 10.1158/2159-8290.CD-20-1201∟. PMID: 34551970∟. Case report. ˍ

Asuzu DT, Bunevicius A, Kormath Anand R, Suleiman M, Nabeel AM, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Chytka T, Liščák R, Sheehan K, Sheehan D, Perez Caceres M, Mathieu D, Lee CC, Yang HC, Picozzi P, Franzini A, Attuati L, Speckter H, Olivo J, Patel S, Cifarelli CP, Cifarelli DT, Hack JD, Strickland BA, Zada G, Chang EL, Fakhoury KR, Rusthoven CG, Warnick RE, Sheehan JP.
Clinical and radiologic outcomes after stereotactic radiosurgery for meningiomas in direct contact with the optic apparatus: an international multicenter study.
J Neurosurg. 2021 Sep 24, 2021:1-7∟. doi: 10.3171/2021.3.JNS21328∟. PMID: 34560648∟. Observational study. ˍ

Cheng L, Wang L, Yao Q, Ma L, Duan W, Guan J, Zhang C, Wang K, Liu Z, Wang X, Wang Z, Wu H, Chen Z, Jian F.
Clinicoradiological characteristics of primary spinal cord H3 K27M-mutant diffuse midline glioma.
J Neurosurg Spine. 2021 Sep 24, 2021:1-12∟. doi: 10.3171/2021.4.SPINE2140∟. PMID: 34560639∟. Observational study. ˍ

Mattoli MV, Trevisi G, Scolozzi V, Capotosti A, Cocciolillo F, Marini I, Mare V, Indovina L, Caulo M, Saponiero A, Balducci M, Taralli S, Calcagni ML.
Dynamic ¹¹C-Methionine PET-CT: Prognostic Factors for Disease Progression and Survival in Patients with Suspected Glioma Recurrence.
Cancers (Basel). 2021 Sep 24, 2021;13(19):4777∟. doi: 10.3390/cancers13194777∟. PMID: 34638262∟. Observational study. ˍ

Medikonda R, Patel K, Jackson C, Saleh L, Srivastava S, Feghali J, Mohan A, Pant A, Jackson CM, Weingart J, Mukherjee D, Bettegowda C, Gallia GL, Brem H, Lim M.
The safety and efficacy of dexamethasone in the perioperative management of glioma patients.
J Neurosurg. 2021 Sep 24, 2021:1-8∟. doi: 10.3171/2021.4.JNS204127∟. PMID: 34560653∟. Observational study. ˍ

Oprandi MC, Oldrati V, Delle Fave M, Panzeri D, Gandola L, Massimino M, Bardoni A, Poggi G.
Processing Speed and Time since Diagnosis Predict Adaptive Functioning Measured with WeeFIM in Pediatric Brain Tumor Survivors.
Cancers (Basel). 2021 Sep 24, 2021;13(19):4776∟. doi: 10.3390/cancers13194776∟. PMID: 34638261∟. Observational study. ˍ

Richardson GE, Gillespie CS, Mustafa MA, Taweel BA, Bakhsh A, Kumar S, Keshwara SM, Ali T, John B, Brodbelt AR, Chavredakis E, Mills SJ, May C, Millward CP, Islim AI, Jenkinson MD.
Clinical Outcomes Following Re-Operations for Intracranial Meningioma.
Cancers (Basel). 2021 Sep 24, 2021;13(19):4792∟. doi: 10.3390/cancers13194792∟. PMID: 34638276∟. Observational study. ˍ

Tseng CH.
Metformin Is Associated with a Lower Incidence of Benign Brain Tumors: A Retrospective Cohort Study in Patients with Type 2 Diabetes Mellitus.
Biomolecules. 2021 Sep 25, 2021;11(10):1405∟. doi: 10.3390/biom11101405∟. PMID: 34680039∟. Observational study. ˍ

Al Shudifat A, Al Suqi H, Soub K, Al Nemrawi L, Abu Jaber M, Al Barbarawi M, Shewaikani N, El Adwan Y, Al Refaei A.
AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics.
Risk Manag Healthc Policy. 2021 Sep 27, 2021;14:4031-4035∟. doi: 10.2147/RMHP.S322546∟. PMID: 34611451∟. Observational study. ˍ

Fletcher-Sananikone E, Kanji S, Tomimatsu N, Macedo Di Cristofaro LF, Kollipara RK, Saha D, Floyd JR, Sung P, Hromas R, Burns TC, Kittler R, Habib AA, Mukherjee B, Burma S.
Elimination of radiation-induced senescence in the brain tumor microenvironment attenuates glioblastoma recurrence.
Cancer Res. 2021 Sep 27, 2021:canres.0752.2021∟. doi: 10.1158/0008-5472.CAN-21-0752∟. PMID: 34580063∟. Laboratory investigation. ˍ

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Ram Z, Kim CY, Hottinger AF, Idbaih A, Nicholas G, Zhu JJ.
Efficacy and Safety of Tumor Treating Fields (TTFields) in Elderly Patients with Newly Diagnosed Glioblastoma: Subgroup Analysis of the Phase 3 EF-14 Clinical Trial.
Front Oncol. 2021 Sep 27, 2021;11:671972∟. doi: 10.3389/fonc.2021.671972∟. PMID: 34692470∟. Interventional study. ˍ

Aoki T, Kagawa N, Sugiyama K, Wakabayashi T, Arakawa Y, Yamaguchi S, Tanaka S, Ishikawa E, Muragaki Y, Nagane M, Nakada M, Suehiro S, Hata N, Kuroda J, Narita Y, Sonoda Y, Iwadate Y, Natsumeda M, Nakazato Y, Minami H, Hirata Y, Hagihara S, Nishikawa R.
Efficacy and safety of nivolumab in Japanese patients with first recurrence of glioblastoma: an open-label, non-comparative study.
Int J Clin Oncol. 2021 Sep 29∟. doi: 10.1007/s10147-021-02028-1∟. PMID: 34586548∟. Interventional study. ˍ

Li J, Huang W, Chen J, Li Z, Liu B, Wang P, Zhang J.
Nomograms for predicting the overall survival of patients with cerebellar glioma: an analysis of the surveillance epidemiology and end results (SEER) database.
Sci Rep. 2021 Sep 29, 2021;11(1):19348∟. doi: 10.1038/s41598-021-98960-3∟. PMID: 34588593∟. Observational study. ˍ

Khan S, Solano-Paez P, Suwal T, Lu M, Al-Karmi S, Ho B, Mumal I, Shago M, Hoffman LM, Dodgshun A, Nobusawa S, Tabori U, Bartels U, Ziegler DS, Hansford JR, Ramaswamy V, Hawkins C, Dufour C, André N, Bouffet E, Huang A; Rare Brain Tumor Registry.
Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study.
Lancet Child Adolesc Health. 2021 Sep 29, 2021;5(11):800-813∟. doi: 10.1016/S2352-4642(21)00245-5∟. PMID: 34599879∟. Observational study˰ ˍ