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Current Neuro-Oncology




Volume 25 Number 18
30 September 2023




Home > Publications > Current Neuro-Oncology > Volume 25, Year 2023 > Number 18, 30 September






Wegener E, Horsley P, Wheeler H, Jayamanne D, Kastelan M, Guo L, Brown C, Back M.
Leptomeningeal neuraxis relapse in glioblastoma is an uncommon but not rare event associated with poor outcome.
BMC Neurol. 2023 Sep 15;23(1):328
. doi: 10.1186/s12883-023-03378-1. PMID: 37715122. Observational study. ˍ




Alanzi AK, Hakmi S, Adeel S, Ghazzal SY.
Anesthesia for awake craniotomy: a case report.
J Surg Case Rep. 2023 Sep 16;2023(9):rjad521
. doi: 10.1093/jscr/rjad521. PMID: 37724066. Case report. ˍ




Johnson TS, MacDonald TJ, Pacholczyk R, Aguilera D, Al-Basheer A, Bajaj M, Bandopadhayay P, Berrong Z, Bouffet E, Castellino RC, Dorris K, Eaton BR, Esiashvili N, Fangusaro JR, Foreman N, Fridlyand D, Giller C, Heger IM, Huang C, Kadom N, Kennedy EP, Manoharan N, Martin W, McDonough C, Parker RS, Ramaswamy V, Ring E, Rojiani A, Sadek RF, Satpathy S, Schniederjan M, Smith A, Smith C, Thomas BE, Vaizer R, Yeo KK, Bhasin MK, Munn DH.
Indoximod-based chemo-immunotherapy for pediatric brain tumors: a first-in-children phase 1 trial.
Neuro Oncol. 2023 Sep 16:noad174
. doi: 10.1093/neuonc/noad174. PMID: 37715730. Interventional study. ˍ




Stritzelberger J, Gesmann A, Fuhrmann I, Balk S, Reindl C, Madžar D, Uhl M, Welte TM, Brandner S, Eisenhut F, Dörfler A, Coras R, Adler W, Schwab S, Putz F, Fietkau R, Distel L, Hamer HM.
Status epilepticus in patients with glioblastoma: Clinical characteristics, risk factors, and epileptological outcome.
Seizure.
2023 Sep 16;112:48-53. doi: 10.1016/j.seizure.2023.09.014. PMID: 37748366. Observational study. ˍ




Marques Da Costa ME, Zaidi S, Scoazec JY, Droit R, Lim WC, Marchais A, Salmon J, Cherkaoui S, Morscher RJ, Laurent A, Malinge S, Mercher T, Tabone-Eglinger S, Goddard I, Pflumio F, Calvo J, Redini F, Entz-Werlé N, Soriano A, Villanueva A, Cairo S, Chastagner P, Moro M, Owens C, Casanova M, Hladun-Alvaro R, Berlanga P, Daudigeos-Dubus E, Dessen P, Zitvogel L, Lacroix L, Pierron G, Delattre O, Schleiermacher G, Surdez D, Geoerger B.
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors.
Commun Biol. 2023 Sep 18;6(1):949
. doi: 10.1038/s42003-023-05320-0. PMID: 37723198. Interventional study. ˍ




Rahman R, Trippa L, Lee EQ, Arrillaga-Romany I, Fell G, Touat M, McCluskey C, Wiley J, Gaffey S, Drappatz J, Welch MR, Galanis E, Ahluwalia MS, Colman H, Nabors LB, Hepel J, Elinzano H, Schiff D, Chukwueke UN, Beroukhim R, Nayak L, McFaline-Figueroa JR, Batchelor TT, Rinne ML, Kaley TJ, Lu-Emerson C, Mellinghoff IK, Bi WL, Arnaout O, Peruzzi PP, Haas-Kogan D, Tanguturi S, Cagney D, Aizer A, Doherty L, Lavallee M, Fisher-Longden B, Dowling S, Geduldig J, Watkinson F, Pisano W, Malinowski S, Ramkissoon S, Santagata S, Meredith DM, Chiocca EA, Reardon DA, Alexander BM, Ligon KL, Wen PY.
Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Randomization.
J Clin Oncol. 2023 Sep 18:JCO2300493
. doi: 10.1200/JCO.23.00493. PMID: 37722087. Interventional study˰ ˍ




Zaed I, Marchi F, Milani D, Cabrilo I, Cardia A.
Role of Enhanced Recovery after Surgery (ERAS) Protocol in the Management of Elderly Patients with Glioblastoma.
J Clin Med. 2023 Sep 18;12(18):6032
. doi: 10.3390/jcm12186032. PMID: 37762972. Observational study. ˍ




Zhou W, Zhang H, An X, Li C, Gong J, Liu W, Sun T, Zhao F, Tian YJ.
A nomogram for predicting post-operative hydrocephalus in children with medulloblastoma.
Neurosurg Rev. 2023 Sep 18;46(1):246
. doi: 10.1007/s10143-023-02156-4. PMID: 37723329. Observational study˰ ˍ




Bonanno M, Bourque CJ, Robichaud LA, Levesque A, Lacoste-Julien A, Rondeau É, Dubé É, Leblanc M, Bertrand MC, Provost C, Desjardins L, Sultan S.
Prioritizing Solutions and Improving Resources among Young Pediatric Brain Tumor Survivors: Results of an Online Survey.
Curr Oncol. 2023 Sep 19;30(9):8586-8601
. doi: 10.3390/curroncol30090623. PMID: 37754538. Observational study. ˍ



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Chandar JS, Bhatia S, Ingle S, Mendez Valdez MJ, Maric D, Seetharam D, Desgraves JF, Govindarajan V, Daggubati L, Merenzon M, Morell A, Luther E, Saad AG, Komotar RJ, Ivan ME, Shah AH.
Laser Interstitial Thermal Therapy Induces Robust Local Immune Response for Newly Diagnosed Glioblastoma with Long-term Survival and Disease Control.
J Immunother. 2023 Sep 19
. doi: 10.1097/CJI.0000000000000485. PMID: 37727953. Case report˰ ˍ




Fan P, Xia J, Zhou M, Zhuo C, He H.
Development and validation of a personalized classifier to predict the prognosis and response to immunotherapy in glioma based on glycolysis and the tumor microenvironment.
PeerJ. 2023 Sep
19;11:e16066. doi: 10.7717/peerj.16066. PMID: 37744243. Observational study. ˍ




Farzana W, Basree MM, Diawara N, Shboul ZA, Dubey S, Lockhart MM, Hamza M, Palmer JD, Iftekharuddin KM.
Prediction of Rapid Early Progression and Survival Risk with Pre-Radiation MRI in WHO Grade 4 Glioma Patients.
Cancers (Basel).
2023 Sep 19;15(18):4636. doi: 10.3390/cancers15184636. PMID: 37760604. Observational study. ˍ




Gibson D, Ravi A, Rodriguez E, Chang S, Oberheim Bush N, Taylor J, Clarke J, Solomon D, Scheffler A, Witte J, Lambing H, Okada H, Berger M, Chehab F, Butowski NA.
Quantitative analysis of MGMT promoter methylation in glioblastoma suggests nonlinear prognostic effect.
Neurooncol Adv. 2023 Sep 19;5(1):vdad115. doi: 10.1093/noajnl/vdad115. PMID: 37899778. Observational study.
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Castelli B, Fonte C, Guidi M, Tellini M, Di Nicola M, Iacono A, Buccoliero AM, Greto D, Genitori L, Sardi I.
Bevacizumab-Irinotecan combination therapy in recurrent low-grade glioma, previously treated with chemo-radiotherapy: a case report.
Front Oncol. 2023 Sep 20;13:1244628. doi: 10.3389/fonc.2023.1244628. PMID: 37799478. Case report. ˍ



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D'Onofrio G, Icolaro N, Fazzari E, Catapano D, Curcio A, Izzi A, Manuali A, Bisceglia G, Tancredi A, Marchello V, Recchia A, Tonti MP, Pazienza L, Carotenuto V, Bonis C, Savarese L, Gaudio AD, Gorgoglione LP.
Real-Time Neuropsychological Testing (RTNT) and Music Listening during Glioblastoma Excision in Awake Surgery: A Case Report.
J Clin Med. 2023 Sep 20;12(18):6086
. doi: 10.3390/jcm12186086. PMID: 37763026. Case report. ˍ




Bouffet E, Hansford JR, Garrè ML, Hara J, Plant-Fox A, Aerts I, Locatelli F, van der Lugt J, Papusha L, Sahm F, Tabori U, Cohen KJ, Packer RJ, Witt O, Sandalic L, Bento Pereira da Silva A, Russo M, Hargrave DR.
Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations.
N Engl J Med.
2023 Sep 21;389(12):1108-1120. doi: 10.1056/NEJMoa2303815. PMID: 37733309. Interventional study. ˍ



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Chang IY, Tsai HC, Chen CH, Chen HC, Huang CW, Cox GF, Huang FM, Lin YY, Chen KT, Lin YJ, Wei KC.
CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden.
Biomed J. 2023 Sep
21:100660. doi: 10.1016/j.bj.2023.100660. PMID: 37741340. Observational study. ˍ




Grassl N, Poschke I, Lindner K, Bunse L, Mildenberger I, Boschert T, Jähne K, Green EW, Hülsmeyer I, Jünger S, Kessler T, Suwala AK, Eisele P, Breckwoldt MO, Vajkoczy P, Grauer OM, Herrlinger U, Tonn JC, Denk M, Sahm F, Bendszus M, von Deimling A, Winkler F, Wick W, Platten M, Sahm K.
A H3K27M-targeted vaccine in adults with diffuse midline glioma.
Nat Med. 2023 Sep 21. doi: 10.1038/s41591-023-02555-6. PMID: 37735561. Expanded access study. ˍ




Østergaard DE, Wahlstedt I, Jørgensen M, Kjærsgaard M, Mathiasen R, Nysom K, Sehested A, Vogelius IR, Maraldo MV.
Dose-accumulation analysis of target and organs at risk with clinical outcome after re-irradiation of diffuse midline glioma.
Acta Oncol. 2023 Sep 21:1-5
. doi: 10.1080/0284186X.2023.2258271. PMID: 37733582. Observational study. ˍ




Visioli A, Trivieri N, Mencarelli G, Giani F, Copetti M, Palumbo O, Pracella R, Cariglia MG, Barile C, Mischitelli L, Soriano AA, Palumbo P, Legnani F, DiMeco F, Gorgoglione L, Pesole G, Vescovi AL, Binda E.
Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies.
J Exp Clin Cancer Res. 2023 Sep 21;42(1):244. doi: 10.1186/s13046-023-02811-0. PMID: 37735434. Laboratory investigation. ˍ




Hung ND, Anh NN, Minh ND, Huyen DK, Duc NM.
Differentiation of glioblastoma and primary central nervous system lymphomas using multiparametric diffusion and perfusion magnetic resonance imaging.
Biomed Rep. 2023 Sep 22;19(5):82. doi: 10.3892/br.2023.1664. PMID: 37881606. Observational study.
ˍ




Lukas RV, Horbinski C.
Glioma Response to IDH Inhibition: Real-World Experience.
Clin Cancer Res. 2023 Sep 22
. doi: 10.1158/1078-0432.CCR-23-2164. PMID: 37738033. Observational study˰ ˍ



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Muench A, Teichmann D, Spille D, Kuzman P, Perez E, May SA, Mueller WC, Kombos T, Nazari-Dehkordi S, Onken J, Vajkoczy P, Ntoulias G, Bettencourt C, von Deimling A, Paulus W, Heppner FL, Koch A, Capper D, Kaul D, Thomas C, Schweizer L.
A Novel Type of IDH Wild-type Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile.
Am
J Surg Pathol. 2023 Sep 22. doi: 10.1097/PAS.0000000000002118. PMID: 37737691. Observational study˰ ˍ




Ospanov A, Romanishkin I, Savelieva T, Kosyrkova A, Shugai S, Goryaynov S, Pavlova G, Pronin I, Loschenov V.
Optical Differentiation of Brain Tumors Based on Raman Spectroscopy and Cluster Analysis Methods.
Int J Mol Sci. 2023 Sep 22;24(19):14432. doi: 10.3390/ijms241914432. PMID: 37833879. Observational study.
ˍ




Shen Y, Zheng D, Hu D, Ma B, Cai C, Chen W, Zeng J, Luo J, Xiao D, Zhao Y, Wu Z, Jing G, Xie Y.
The prognostic value of tumor-associated macrophages in glioma patients.
Medicine (Baltimore). 2023 Sep 22;102(38):e35298
. doi: 10.1097/MD.0000000000035298. PMID: 37747032. Observational study. ˍ




Sim HW, Wachsmuth L, Barnes EH, Yip S, Koh ES, Hall M, Jennens R, Ashley DM, Verhaak RG, Heimberger AB, Rosenthal MA, Hovey EJ, Ellingson BM, Tognela A, Gan HK, Wheeler H, Back M, McDonald KL, Long A, Cuff K, Begbie S, Gedye C, Mislang A, Le H, Johnson MO, Kong BY, Simes JR, Lwin Z, Khasraw M.
NUTMEG: A randomized phase II study of nivolumab and temozolomide versus temozolomide alone in newly diagnosed older patients with glioblastoma.
Neurooncol Adv. 2023 Sep 22;5(1):vdad124. doi: 10.1093/noajnl/vdad124. PMID: 37841696. Interventional study.
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Majós C, Pons-Escoda A, Naval P, Güell A, Lucas A, Vidal N, Cos M, Bruna J.
Proton MR spectroscopy shows improved performance to segregate high-grade astrocytoma subgroups when defined with the new 2021 World Health Organization classification of central nervous system tumors.
Eur Radiol. 2023 Sep 23
. doi: 10.1007/s00330-023-10138-9. PMID: 37740778. Observational study˰ ˍ




Tiefenbach J, Toljan K, Khawam EA, Viguera AC.
Presenting symptoms of religious delusions and hallucinations in temporal lobe glioblastoma.
Psychiatr
Danub. 2023 Fall (0923);35(3):451-453. doi: 10.24869/psyd.2023.451. PMID: 37917853. Case report. ˍ




Fukuoka K, Kurihara J, Shofuda T, Kagawa N, Yamasaki K, Ando R, Ishida J, Kanamori M, Kawamura A, Park YS, Kiyotani C, Akai T, Keino D, Miyairi Y, Sasaki A, Hirato J, Inoue T, Nakazawa A, Koh K, Nishikawa R, Date I, Nagane M, Ichimura K, Kanemura Y.
Subtyping of Group 3/4 medulloblastoma as a potential prognostic biomarker among patients treated with reduced dose of craniospinal irradiation: a Japanese Pediatric Molecular Neuro-Oncology Group study.
Acta Neuropathol
Commun. 2023 Sep 25;11(1):153. doi: 10.1186/s40478-023-01652-4. PMID: 37749662. Observational study. ˍ




Li M, Liu M, Cui Q, Zeng M, Li S, Zhang L, Peng Y.
Effect of dexmedetomidine on postoperative delirium in patients undergoing awake craniotomies: study protocol of a randomized controlled trial.
Trials. 2023 Sep 25;24(1):607
. doi: 10.1186/s13063-023-07632-2. PMID: 37743486. Interventional study protocol. ˍ



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Morgacheva D, Ryzhova M, Zheludkova O, Belogurova M, Dinikina Y.
DNA methylation-based diagnosis confirmation in a pediatric patient with low-grade glioma: a case report.
Front Pediatr. 2023 Sep 25;11:1256876. doi: 10.3389/fped.2023.1256876. PMID: 37818165. Case report.
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Bjorland LS, Mahesparan R, Fluge Ø, Gilje B, Dæhli Kurz K, Farbu E.
Impact of extent of resection on outcome from glioblastoma using the RANO resect group classification system: a retrospective, population-based cohort study.
Neurooncol Adv. 2023 Sep 26;5(1):vdad126. doi: 10.1093/noajnl/vdad126. PMID: 37868696. Observational study.
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Günerhan G, Öcal Ö, Dağlar Z, Çağıl E, Ertuğrul Y, Belen AD.
The influence of glioblastoma on patients' cognitive and demographic characteristics and psychological well-being of patients and caregivers: a single-centre retrospective study.
Psychogeriatrics. 2023 Sep 26
. doi: 10.1111/psyg.13029. PMID: 37752061. Observational study˰ ˍ




Maas RR, Soukup K, Fournier N, Massara M, Galland S, Kornete M, Wischnewski V, Lourenco J, Croci D, Álvarez-Prado ÁF, Marie DN, Lilja J, Marcone R, Calvo GF, Santalla Mendez R, Aubel P, Bejarano L, Wirapati P, Ballesteros I, Hidalgo A, Hottinger AF, Brouland JP, Daniel RT, Hegi ME, Joyce JA.
The local microenvironment drives activation of neutrophils in human brain tumors.
Cell. 2023 Sep 27:S0092-8674(23)00977-7
. doi: 10.1016/j.cell.2023.08.043. PMID: 37769657. Laboratory investigation. ˍ




Remes TM, Suo-Palosaari MH, Arikoski PM, Harila M, Koskenkorva PKT, Lähteenmäki PM, Lönnqvist TRI, Ojaniemi MK, Pohjasniemi H, Puosi R, Ritari N, Sirkiä KH, Sutela AK, Toiviainen-Salo SM, Rantala HMJ, Harila AH.
Radiotherapy-induced vascular cognitive impairment 20 years after childhood brain tumor.
Neuro Oncol. 2023 Sep 27:noad186
. doi: 10.1093/neuonc/noad186. PMID: 37758202. Observational study˰ ˍ




Saijo A, Ogino H, Butowski NA, Tedesco MR, Gibson D, Watchmaker PB, Okada K, Wang AS, Shai A, Salazar AM, Molinaro AM, Rabbitt JE, Shahin M, Perry A, Clarke JL, Taylor JW, Daras M, Oberheim Bush NA, Hervey-Jumper SL, Phillips JJ, Chang SM, Hilf N, Mayer-Mokler A, Keler T, Berger MS, Okada H.
A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas.
Neuro Oncol. 2023 Sep 27:noad185
. doi: 10.1093/neuonc/noad185. PMID: 37758193. Interventional study˰ ˍ




Srinivasan S, Hegde A, Nair R, Menon G.
Medulloblastoma with Subcutaneous Spread: A Rare Entity.
Asian J Neurosurg. 2023 Sep 27;18(3):698-700. doi: 10.1055/s-0043-1774822. PMID: 38152545. Case report.
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van der Meer PB, Dirven L, Fiocco M, Vos MJ, Kerkhof M, Kouwenhoven MCM, van den Bent MJ, Taphoorn MJB, Koekkoek JAF.
Impact of timing of antiseizure medication withdrawal on seizure recurrence in glioma patients: a retrospective observational study.
J Neurooncol. 2023 Sep 27
. doi: 10.1007/s11060-023-04450-z. PMID: 37755633. Observational study. ˍ




Demetz M, Mangesius J, Krigers A, Nevinny-Stickel M, Thomé C, Freyschlag CF, Kerschbaumer J.
Tumor Location Impacts the Development of Radiation Necrosis in Benign Intracranial Tumors.
Cancers (Basel). 2023 Sep 28;15(19):4760. doi: 10.3390/cancers15194760. PMID: 37835452.
Observational study. ˍ



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Hu LS, D'Angelo F, Weiskittel TM, Caruso FP, Fortin Ensign SP, Blomquist MR, Flick MJ, Wang L, Sereduk CP, Meng-Lin K, De Leon G, Nespodzany A, Urcuyo JC, Gonzales AC, Curtin L, Lewis EM, Singleton KW, Dondlinger T, Anil A, Semmineh NB, Noviello T, Patel RA, Wang P, Wang J, Eschbacher JM, Hawkins-Daarud A, Jackson PR, Grunfeld IS, Elrod C, Mazza GL, McGee SC, Paulson L, Clark-Swanson K, Lassiter-Morris Y, Smith KA, Nakaji P, Bendok BR, Zimmerman RS, Krishna C, Patra DP, Patel NP, Lyons M, Neal M, Donev K, Mrugala MM, Porter AB, Beeman SC, Jensen TR, Schmainda KM, Zhou Y, Baxter LC, Plaisier CL, Li J, Li H, Lasorella A, Quarles CC, Swanson KR, Ceccarelli M, Iavarone A, Tran NL.
Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures.
Nat Commun. 2023 Sep 28;14(1):6066
. doi: 10.1038/s41467-023-41559-1. PMID: 37770427. Observational study. ˍ




Ruis C, Robe PA, Dijkerman HC.
Preserving the ability to discriminate between left and right; A case study.
J Neuropsychol. 2023 Sep 28
. doi: 10.1111/jnp.12348. PMID: 37771271. Case report. ˍ




Schaufler A, Sanin AY, Sandalcioglu IE, Hartmann K, Croner RS, Perrakis A, Wartmann T, Boese A, Kahlert UD, Fischer I.
Concept of a fully-implantable system to monitor tumor recurrence.
Sci Rep. 2023 Sep 29;13(1):16362
. doi: 10.1038/s41598-023-43226-3. PMID: 37773315. Laboratory investigation. ˍ




Yu H, Chen M, Huang Y, Wang P, Li J, Li Q, Jiang R.
Differential Diagnosis of Intracranial Malignant Tumors Using MRI Based on Morphological Features and Signal Intensity Ratio of Lesions.
Altern Ther Health Med. 2023 Sep 29:AT8218
. PMID: 37773646. Observational study. ˍ




Ertzgaard P, Nyman P, Jakobsson M, Johansson J.
Oculomotor screening and neuro-visual rehabilitation following pediatric brain tumor resection.
J Pediatr Rehabil Med. 2023 Sep 30. doi: 10.3233/PRM-220127. PMID: 37807791. Case report.
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Kanematsu R, Mizuno M, Inoue T, Takahashi T, Endo T, Shigekawa S, Muto J, Umebayashi D, Mitsuhara T, Hida K, Hanakita J; Investigators of Intramedullary Spinal Cord Tumors in the Neurospinal Society of Japan.
The Impact of Adjuvant Radiotherapy on Clinical Performance Status in Patients With Grade II Spinal Cord Astrocytoma - A Nationwide Analysis by the Neurospinal Society of Japan.
Neurospine. 2023 Sep 30;20(3):766-773. doi: 10.14245/ns.2346386.193. PMID: 37798968. Observational study. ˍ




Karlberg A, Pedersen LK, Vindstad BE, Skjulsvik AJ, Johansen H, Solheim O, Skogen K, Kvistad KA, Bogsrud TV, Myrmel KS, Giskeødegård GF, Ingebrigtsen T, Berntsen EM, Eikenes L.
Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas.
Eur J Nucl Med Mol Imaging. 2023 Sep 30. doi: 10.1007/s00259-023-06437-4. PMID: 37776502. Interventional study. ˍ




Muto J, Murata H, Shigekawa S, Mitsuhara T, Umebayashi D, Kanematsu R, Joko M, Inoue T, Inoue T, Endo T, Hirose Y; Investigators of Intramedullary Spinal Cord Tumors in the Neurospinal Society of Japan.
Clinical Characteristics and Long-term Outcomes of Spinal Pilocytic Astrocytomas: A Multicenter Retrospective Study by the Neurospinal Society of Japan.
Neurospine. 2023 Sep 30;20(3):774-782. doi: 10.14245/ns.2346450.225. PMID: 37798969. Observational study. ˍ