Current Neuro-Oncology

Volume 27 Number 4
10 February 2025

Home > Publications > Current Neuro-Oncology > Volume 27, Year 2025 > Number 4, 10 February

Hinz F, Friedel D, Korshunov A, Ippen FM, Bogumil H, Banan R, Brandner S, Hasselblatt M, Boldt HB, Dirse V, Dohmen H, Aronica E, Brodhun M, Broekman MLD, Capper D, Cherkezov A, Deng MY, van Dis V, Felsberg J, Frank S, French PJ, Gerlach R, Göbel K, Goold E, Hench J, Kantelhardt S, Kohlhof-Meinecke P, Krieg S, Mawrin C, Morrison G, Mühlebner A, Ozduman K, Pfister SM, Poliani PL, Prinz M, Reifenberger G, Riemenschneider MJ, Sankowski R, Schrimpf D, Sill M, Snuderl M, Verdijk RM, Voisin MR, Wesseling P, Wick W, Reuss DE, von Deimling A, Sahm F, Maas SLN, Suwala AK.
IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread.
Acta Neuropathol. 2025 Feb 3;149(1):12. doi: 10.1007/s00401-025-02849-8. PMID: 39899075. Observational study. ˍ

Jiang H, Wang X, Chen X, Zhang S, Ren Q, Li M, Li M, Ren X, Lin S, Cui Y.
Unraveling the heterogeneity of WHO grade 4 gliomas: insights from clinical, imaging, and molecular characterization.
Discov Oncol. 2025 Feb 3;16(1):111. doi: 10.1007/s12672-025-01811-0. PMID: 39899184. Observational study. ˍ

Bonada M, Baso G, Lorenzini D, Marucci G, Silvani A, DiMeco F, Del Bene M.
Intracranial extranodal marginal zone lymphoma mimicking meningioma: A rare but insidious entity.
Neurooncol Adv. 2025 Feb 4;7(1):vdaf031. doi: 10.1093/noajnl/vdaf031. PMID: 40321616. Case report. ˍ

Huang X, Cao Y, Zhang G, Tang F, Sun D, Ren J, Li W, Zhou J, Zhang J.
MRI morphological features combined with apparent diffusion coefficient can predict brain invasion in meningioma.
Comput Biol Med. 2025 Feb 4;187:109763. doi: 10.1016/j.compbiomed.2025.109763. PMID: 39908915. Observational study˰ ˍ

Lv XQ, Shen WR, Guo Z, Xie XD.
Diagnostic value and efficacy of multimodal magnetic resonance imaging in differentiating radiation necrosis from tumor recurrence in glioblastomas.
Acta Radiol. 2025 Feb 4:2841851241310392. doi: 10.1177/02841851241310392. PMID: 39905844. Observational study˰ ˍ

Zaghloul MS, Bishr MK, Refaat A, Hemaly AE, Ayadi MA, Ahmed S, Maher E, Todary ES.
Re-Irradiation for the Progressive Pediatric Diffuse Intrinsic Pontine Glioma: A Report on 109 Children From a Single Center.
Pediatr Blood Cancer. 2025 Feb 4:e31587. doi: 10.1002/pbc.31587. PMID: 39905588. Observational study˰ ˍ

Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh SAO, Kim MM, Minn AJ, Dorsey JF, Foster JB, Metz J, Koumenis C, Kirsch DG, Gong Y, Fan Y.
FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy.
Nat Cancer. 2025 Feb 5. doi: 10.1038/s43018-025-00905-6. PMID: 39910249. Laboratory investigation˰ ˍ

Pham J, Cote DJ, Kang K, Briggs RG, Gomez D, Prasad A, Daggupati S, Sisti J, Chow F, Attenello F, Chen CC, Zada G.
Treatment practices and survival outcomes for IDH-wildtype glioblastoma patients according to MGMT promoter methylation status: insights from the U.S. National Cancer Database.
J Neurooncol. 2025 Feb 5. doi: 10.1007/s11060-025-04952-y. PMID: 39907975. Observational study. ˍ

Hallak H, Mantziaris G, Pikis S, Islim AI, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Mathieu D, Lee CC, Liscak R, Alvarez RM, Kondziolka D, Tripathi M, Speckter H, Bowden GN, Benveniste RJ, Lunsford LD, Jenkinson MD, Sheehan J.
A retrospective comparison of active surveillance to stereotactic radiosurgery for the management of elderly patients with an incidental meningioma.
Acta Neurochir (Wien). 2025 Feb 6;167(1):37. doi: 10.1007/s00701-025-06452-4. PMID: 39912992. Observational study. ˍ

Mirzayeva LS, Uçar M, Budak SN, Kaymaz AM, Yaylı N.
Pushing the boundaries of neurosurgical oncology: evaluating the superiority of supratotal resection over gross total resection in intraoperative MRI-guided glioma surgery.
Neurosurg Rev. 2025 Feb 6;48(1):200. doi: 10.1007/s10143-025-03301-x. PMID: 39909935. Observational study. ˍ

Nasika VKNK, Subramani V, Sharma A, Singh S, Sethi J, Paladugu S, Jain K, Bansal N.
Recipient Outcomes After Utilization of Kidneys From Deceased Donors With Diagnosed Glioblastoma Multiforme.
Clin Transplant. 2025 Feb 6;39(2):e70090. doi: 10.1111/ctr.70090. PMID: 39912618. Observational study˰ ˍ

Restelli F, Pollo B, Mazzapicchi E, Tramacere I, Broggi M, Falco J, Schiariti M, Stanziano M, Dimeco F, Ferroli P, Marucci G, Vetrano IG, Acerbi F.
Confocal endomicroscopy accuracy in identifying central nervous system tumors tissue at the infiltration margins: results from a prospective clinical trial.
J Neurosurg Sci. 2025 Feb 6. doi: 10.23736/S0390-5616.24.06302-1. PMID: 39911086. Interventional study. ˍ

*Mangena V, Chanoch-Myers R, Sartore R, Paulsen B, Gritsch S, Weisman H, Hara T, Breakefield XO, Breyne K, Regev A, Chung K, Arlotta P, Tirosh I, Suvà ML.
Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer.
Cancer Discov. 2025 Feb 7;15(2):299-315. doi: 10.1158/2159-8290.CD-23-1336. PMID: 39373549 Laboratory investigation. ˍ
RELATED ARTICLE
Shakya S, Hubert CG, Lathia JD.
A Material Transfer Agreement between Glioblastoma and Normal Brain Cells.
Cancer Discov. 2025 Feb 7;15(2):261-263. doi: 10.1158/2159-8290.CD-24-1661. PMID: 39916523. Comment˰ ˍ

Tathe SP, Jaiswal KN.
Clear-cell meningioma: An uncommon aggressive variant of meningioma.
Indian J Pathol Microbiol. 2025 Feb 7. doi: 10.4103/ijpm.ijpm_349_24. PMID: 39918240. Observational study. ˍ

Sahebjam S, Raval RR, Forsyth PA, Enderling H, Tran ND, Arrington JA, Macaulay R, Perlow HK, Palmer JD, Ghose J, Rajappa P, Giglio P, Li Z, Etame AB, Mokhtari S, Cruz-Chamorro RJ, Bhandari M, Thapa R, Robinson TJ, Chen DT, Yu HM.
Phase 1 trial of hypofractionated stereotactic re-irradiation in combination with nivolumab, ipilimumab, and bevacizumab for recurrent high-grade gliomas.
Neurooncol Adv. 2025 Feb 8;7(1):vdaf033. doi: 10.1093/noajnl/vdaf033. PMID: 40134851. Interventional study. ˍ

Wang X, Xie Z, Wang X, Song Y, Suo S, Ren Y, Hu W, Zhu Y, Cao M, Zhou Y.
Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-weighted imaging.
Cancer Imaging. 2025 Feb 8;25(1):11. doi: 10.1186/s40644-025-00829-5. PMID: 39923105. Observational study. ˍ

McParland K, Koh ES, Kong B, Sim HW, Thavaneswaran S, Yip S, Barnes EH, Ballinger ML, Thomas DM, De Abreu Lourenco R, Simes J, Sebastian L, Wheeler PJ, Spyridopoulos D, Hawkins C, Pitz M, O'Callaghan C, Gan HK.
Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2): study protocol for a phase 2, prospective, multicentre, open-label, multiarm, biomarker-directed, signal-seeking, umbrella, clinical trial for recurrent IDH mutant, grade 2/3 glioma.
BMJ Open. 2025 Feb 10;15(2):e087922. doi: 10.1136/bmjopen-2024-087922. PMID: 39929517. Interventional study protocol. ˍ