Current Neuro-Oncology

Volume 27 Number 23
20 August 2025

Home > Publications > Current Neuro-Oncology > Volume 27, Year 2025 > Number 23, 20 August

Glioblastoma; Oligodendroglioma

Blumenfeld P, Pryanichnikov A, Hillman Y, Wajnryt E, Berger A, Winograd S, Wygoda M, Salhab A, Fang M, Feldman J, Popovtzer A.
Prospective clinical trial of upright image-guided proton therapy for locally recurrent head and neck and brain malignancies.
Radiother Oncol. 2025 Aug 11;211:111097. doi: 10.1016/j.radonc.2025.111097. PMID: 40803484. Interventional study. ˍ

Li HY, Lao IH, Chen YC, Wu YY, Chu YC, Wei KC, Chen PY, Yeh CC, Chen WC, Chang WH, Chang HT, Chen KT.
Impact of Subventricular Zone Invasion on Preoperative Cognitive Decline in Patients with Diffuse Glioma.
Neurosurgery. 2025 Aug 11. doi: 10.1227/neu.0000000000003676. PMID: 40788002. Observational study. ˍ

Chen Y, Fei W, Shi Y, Ma W, Jiao W, Tao F, Zhu J, Wang Y, Feng X.
Venous thromboembolism risk factors in pediatric patients with high-grade glioma: a multicenter retrospective study.
Front Pediatr. 2025 Aug 12;13:1595223. doi: 10.3389/fped.2025.1595223. PMID: 40873733. Observational study. ˍ

Depond CC, Jecko V, Weller J, Tuppin P, Metellus P.
Overall survival after carmustine wafers implantation for newly-diagnosed high grade glioma. A nationwide population-based controlled propensity score-matched analysis.
Clin Neurol Neurosurg. 2025 Aug 12;257:109081. doi: 10.1016/j.clineuro.2025.109081. PMID: 40848613. Observational study˰ ˍ

Bzour A, Alzoubi Q, Sarhan N, Kh Ibrahimi A, Obeidat M, Musharbash A, Al-Hussaini M, Maraqa B, Amayiri N.
Urgent Chemotherapy for Swift Symptom Relief in Patients With Medulloblastoma.
Pediatr Blood Cancer. 2025 Aug 13;72(11):e31989. doi: 10.1002/pbc.31989. PMID: 40880101. Case report˰ ˍ

Tang H, Dai Q, Zhao Z, Ge W, Li D, Chang Z, Pi P, Li J, Sun Z.
Melatonin Synergises the Chemotherapeutic Effect of Temozolomide in Glioblastoma by Suppressing NF-κB/COX-2 Signalling Pathways.
J Cell Mol Med. 2025 Aug 13;29(15):e70778. doi: 10.1111/jcmm.70778. PMID: 40804775. Lab investigation. ˍ

Rha SY, Castanon E, Gill S, Senellart H, Lopez J, Márquez-Rodas I, Victoria I, Kim TM, Lwin Z, Burger MC, Simonelli M, Cassier PA, Hendifar AE, Ascierto PA, Dutcus C, Okpara CE, Ghori R, Jin F, Groisberg R, Villanueva L.
Lenvatinib plus pembrolizumab for patients with previously treated select solid tumors: Results from the phase 2 LEAP-005 study recurrent glioblastoma cohort.
Cancer. 2025 Aug 15;131(16):e70015. doi: 10.1002/cncr.70015. PMID: 40808295. Interventional study. ˍ ClinicalTrials.gov ID: NCT03797326.

Taiwo R, Harary PM, Trinh TTH, Granucci M, Bertrand S, Carlson-Clarke B, Chernikova SB, Therkelsen K, Arora M, Melisko ME, Iv M, Vogel H, Han S, Xie C, Brain S, Lee V, Bharani KL, Nagpal S, Hayden Gephart M.
Adaptive cohort design and LAT1 expression scale: study protocol for a Phase 2a trial of QBS72S in breast cancer brain metastases.
BMC Cancer. 2025 Aug 15;25(1):1316. doi: 10.1186/s12885-025-14282-x. PMID: 40813655. Interventional study protocol. ˍ ClinicalTrials.gov ID: NCT05305365.

Barish ME, Aftabizadeh M, Hibbard J, Blanchard MS, Ostberg JR, Wagner JR, Manchanda M, Paul J, Stiller T, Aguilar B, Starr R, Arvanitis L, Ressler JA, Kilpatrick J, Kong Y, Wang D, Forman SJ, D'Apuzzo M, Brown CE, Badie B.
Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety.
Cell Rep Med. 2025 Aug 15;6(8):102302. doi: 10.1016/j.xcrm.2025.102302. PMID: 40818458. Interventional study. ˍ ClinicalTrrials.gov ID: NCT04214392.

Jacobsen J, Locallo A, O'Rourke CJ, Carlsen JF, Cohen J, Ewald JD, Scheie D, Grunnet K, Schmidt AY, Melchior LC, Larsen VA, Andersen JB, Poulsen HS, Weischenfeldt J, Broholm H, Michaelsen SR, Kristensen BW.
Clinical, Radiological, and Molecular Insights into Extracranial Metastases from Adult Gliomas.
Neuro Oncol. 2025 Aug 16:noaf178. doi: 10.1093/neuonc/noaf178. PMID: 40842361. Observational study. ˍ

Kaley TJ, Grommes C, Coffee E, Young RJ, Morrison T, Daher A, Schaff LR, Deng Y, Nandakumar S, Diamond EL, DeAngelis LM, Panageas KS, Gavrilovic I, Lin A, Pentsova E, Stone J, Santomasso BD, Piotrowski AF, Nair S, Schultz N, Reiner AS, Mellinghoff IK.
Multicenter basket trial for Central Nervous System tumors identifies activity of the CDK4/6 inhibitor abemaciclib in recurrent meningioma.
Neuro Oncol. 2025 Aug 16:noaf184. doi: 10.1093/neuonc/noaf184. PMID: 40842355. Interventional study˰ ˍ

Gry HS, Falk Delgado A.
Differentiation of Molecular Glioblastomas and Lower-grade Diffuse Astrocytomas Using MRI Perfusion and Diffusion Parameters.
Clin Neuroradiol. 2025 Aug 20. doi: 10.1007/s00062-025-01550-3. PMID: 40833458. Observational study˰ ˍ

Yogendran LV, Kareddy A, Abbas SO, Scharf Z, Patrie J, Patel SH, Schiff D.
Effects of re-challenge with temozolomide in grade 2/3 IDH mutant gliomas at first progression.
J Neurooncol. 2025 Aug 20. doi: 10.1007/s11060-025-05087-w. PMID: 40836201. Observational study. ˍ