Current Neuro-Oncology




Volume 27 Number 24
31 August 2025




Home > Publications > Current Neuro-Oncology > Volume 27, Year 2025 > Number 24, 31 August






Drummond KJ, Spiteri M, Cain SA, Jones J, Shaya S, Topp M, Lu T, Tobler R, Valkovic AL, Moore Z, Fatunla OE, Kriel J, Moffet JJD, McAlpine H, Rosier M, Guan H, Dimou J, Schadewaldt V, Roberts-Thomson S, McArdle D, Lui E, Voelker-Albert M, di Sanzo S, Nijagal B, Narayana VK, Mitchell CB, Vissers JHA, Grimmond S, Rosenthal MA, Palmer LM, Best SA, Freytag S, Whittle JR.
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial.
Nat Med. 2025 Aug 21. doi: 10.1038/s41591-025-03884-4. PMID: 40841487. Interventional study. ˍ ClinicalTrials.gov ID: NCT05577416.




Kang Z, Li S, Wang L, Chen Q, Hu W, Lei T, Mao Y, Zhang J, Xiang X, Wang Q, He Z, Sun T, Wang Y, Huang M, Zhang R, Chen F, Li W.
SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High-Grade Gliomas: A Multicenter, Open-Label Phase I Study.
Ann Clin Transl Neurol. 2025 Aug 22. doi: 10.1002/acn3.70166. PMID: 40847460. Interventional study. ˍ ChiCTR.org.cn ID: ChiCTR2100045380.




Kawabata S, Goto H, Narita Y, Furuse M, Nonoguchi N, Shidoh-Kazuki R, Eza K, Hirose K, Ohno M, Kondo N, Suzuki M, Tanaka H, Ono K, Nihei K, Wanibuchi M, Miyatake SI.
Extended follow-up of recurrent glioblastoma patients treated with boron neutron capture therapy (BNCT): Long-term survival from a Phase II trial (JG002) using Cyclotron Neutron Source and Boronophenylalanine.
Appl Radiat Isot. 2025 Aug 22;226:112118. doi: 10.1016/j.apradiso.2025.112118. PMID: 40865370. Interventional study˰ ˍ




Maffezzini M, Musio S, Di Ianni N, Rumolo A, Patanè M, Galluzzo A, Sambruni I, Berlendis A, Aquino D, Baso G, Zingarelli M, Facciolla M, Maddaloni L, Valentino R, Paterra R, Agistri F, Farinotti M, Mattei L, Coluccia P, Acerbi F, DiMeco F, Pollo B, Silvani A, Eoli M, Traversari C, Montagna D, Pellegatta S.
Polyclonal expansion of functional tumor-reactive lymphocytes infiltrating glioblastoma for personalized cell therapy.
Nat Commun. 2025 Aug 25;16(1):7279. doi: 10.1038/s41467-025-62263-2. PMID: 40855052. Translational study. ˍ




Daftari M, Ramsoomair CK, Aaronson D, Seetharam D, Andreae EA, Wright L, Han S, Chandar J, Lu V, Govindarajan V, Ivan ME, Komotar RJ, de la Fuente M, Shah AH.
Synergistic Treatment with Antiretrovirals and Laser Interstitial Thermal ThErapy (STARLITE) for unresectable glioblastoma: A phase 1 study protocol.
PLoS One. 2025 Aug 28;20(8):e0328204. doi: 10.1371/journal.pone.0328204. PMID: 40875628. Interventional study protocol. ˍ




Lee A, Cole BL, Ojemann J, Kittle D, Perry J, Parrish-Novak J, Miller DM, Hansen S, Harrington K, Ishak L, Gombotz C, Starr K, Poliachik SL, Leary SES.
Phase 1 and expanded imaging study of tozuleristide in patients with pediatric primary central nervous system tumors.
J Neurosurg Pediatr. 2025 Aug 29:1-11. doi: 10.3171/2025.5.PEDS24630. PMID: 40882241. Interventional study˰ ˍ