Current Neuro-Oncology

Volume 27 Number 33
30 November 2025

Home > Publications > Current Neuro-Oncology > Volume 27, Year 2025 > Number 33, 30 November

Liu X, Huangfu L, Wang L, Ding J, Li T, Yu Y, Liu Y, Zhang M, Dai Z, Zheng Y.
Sonodynamic Therapy with Chemo-Radiotherapy in High-Grade Brainstem Gliomas: A Prospective Phase IIa Clinical Trial.
Photodiagnosis Photodyn Ther. 2025 Nov 22:105296. doi: 10.1016/j.pdpdt.2025.105296. PMID: 41285303. Interventional study. ˍ

Chen KT, Tsai HC, Huang CY, Liau CT, Ho KC, Toh CH, Chuang CC, Hsu PW, Huang YC, Chang TW, Yeap MC, Chen PY, Lee CC, Lin YJ, Feng LY, Airan RD, Li G, Lim M, Liu HL, Wei KC.
Combination of Neuronavigation-Guided Focused Ultrasound and Bevacizumab for Patients With Recurrent Glioblastoma: A Pilot Study.
Neurosurgery. 2025 Nov 24. doi: 10.1227/neu.0000000000003851. PMID: 41283685. Interventional study. ˍ

Karschnia P, Young JS, Wijnenga MMJ, Sciortino T, Teske N, Corell A, Wagner A, Youssef G, Park YW, Häni L, Jünger ST, Dono A, Ehret F, Mireles EEM, Neidert N, Bruno F, Tuchek CA, van der Vaart T, Rossi M, Nibali MC, Gay L, Gramelt A, Tandon N, Ahn SS, Chang JH, Weller M, Vincent AJPE, Goldbrunner R, Cahill DP, Huang RY, Raabe A, Meyer B, Beck J, Molinaro AM, Chang SM, Vogelbaum MA, Rudà R, Vik-Mo EO, Dietrich J, Esquenazi Y, Grau SJ, Wen PY, Jakola AS, Schnell O, Bello L, van den Bent MJ, Hervey-Jumper S, Berger MS, Tonn JC.
A prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: an international, multicentre, retrospective cohort study with external validation by the RANO resect group.
Lancet Oncol. 2025 Nov 24;26(12):1638-1650. doi: 10.1016/S1470-2045(25)00534-0. PMID: 41308678. Observational study. ˍ

Kassaeyan V, Arashlow FT, Ahmadi S, Mosayebi N, Bastani P.
Do Glioma Cells Rewire Neural Circuits through Epigenetic Changes? DNA Methylation Analysis of Genes Involved in Neuron-Glioma Communication in the Human Frontal Cortex.
J Mol Neurosci. 2025 Nov 24;75(4):155. doi: 10.1007/s12031-025-02442-4. PMID: 41283964. Laboratory investigation˰ ˍ

Woodworth GF, Anastasiadis P, Ozair A, Chabros J, Bettegowda C, Chen C, Gerstl JVE, Douville C, Mekary RA, Smith TR, Meng Y, Hawkins C, Pople CB, Abrahao A, Llinas M, Heyn C, Bunevicius A, Rezai AR, Ball AJS, Henry K, Sahgal A, Torio E, Ren H, Ahmad H, Arora H, Eisenberg H, Perry J, Carpenter JS, Hynynen K, Pham LC, Anketell MB, Lim-Fat MJ, Xu Z, Cifarelli CP, Sheehan JP, McDannold NJ, Gandhi D, Golby AJ, Lipsman N.
Microbubble-enhanced transcranial focused ultrasound with temozolomide for patients with high-grade glioma (BT008NA): a multicentre, open-label, phase 1/2 trial.
Lancet Oncol. 2025 Nov 24;26(12):1651-1664. doi: 10.1016/S1470-2045(25)00492-9. PMID: 41308679. Interventional study˰ ˍ

Sanai N, Tovmasyan A, Tien AC, Chang YW, Margaryan T, Knight W, Hendrickson K, Eschbacher J, Harmon J, Hong A, Yoo W, Furey C, Marcus SL, Alhilali L, Barani I, Mirzadeh Z, Mehta S.
An early clinical trial of 5-ALA sonodynamic therapy in recurrent high-grade glioma.
Sci Transl Med. 2025 Nov 26;17(826):eads5813. doi: 10.1126/scitranslmed.ads5813. PMID: 41296829. Interventional study. ˍ

Shin KW, Oh H, Kim J, Kim YJ, Park HP, Cho YJ.
A high preoperative prognostic nutritional index is associated with improved overall survival in patients undergoing brain tumor resection.
J Clin Neurosci. 2025 Nov 27;143:111769. doi: 10.1016/j.jocn.2025.111769. PMID: 41314175. Observational study˰ ˍ

Huseyinoglu Z, Uysal E, Inan MA, Demirci T, Gokay G, Aras FK, Erdamar S, Ozduman K, Pamir MN, Danyeli AE.
Optimal qMSP cutoff value for MGMT promoter methylation in glioblastoma and its validation for clinical significance.
BMC Cancer. 2025 Nov 28;25(1):1833. doi: 10.1186/s12885-025-15225-2. PMID: 41316075. Observational study. ˍ

Roldan Urgoiti G, de Robles P, Tsang RY, Willson M, Ghosh S, Faruqi M, Lim G, Loewen S, Nordal R, Cairncross G, Leckie C, Poon CC, Yong VW.
A phase I-II study of niacin in patients with newly diagnosed glioblastoma: safety and interim phase II analysis.
J Neurooncol. 2025 Nov 28;176(1):101. doi: 10.1007/s11060-025-05351-z. PMID: 41313494. Interventional study˰ ˍ

Yoo J, Jung IH, Chang WS, Jung HH, Park HH, Moon JH, Kim EH, Kang SG, Chang JH.
Neoadjuvant gamma knife surgery for metastatic brain tumor: clinical use and impact on leptomeningeal seeding.
J Neurooncol. 2025 Nov 28;176(1):100. doi: 10.1007/s11060-025-05345-x. PMID: 41313358. Observational study˰ ˍ

Harwood DSL, Artzi SB, Pedersen V, Locallo A, Lü MJS, Scheie D, Nørøxe DS, Hammouda NM, Lassen U, Weischenfeldt J, Kristensen BW.
Genomic heterogeneity drives distinct infiltration patterns in glioblastoma.
Acta Neuropathol Commun. 2025 Nov 29. doi: 10.1186/s40478-025-02106-9. PMID: 41316429. Laboratory investigation. ˍ

Cardenas A, Sutlief S, Pajonk F.
Targeting Radiation-Induced Glioma-Initiating Cells in Patient-Derived Glioblastoma.
bioRxiv [Preprint]. 2025 Oct 9:2025.10.08.681196. doi: 10.1101/2025.10.08.681196. PMID: 41279918. Laboratory investigation. ˍ

Helekar SA, Ijare OB, Sharpe MA, Pichumani K, Baskin DS.
Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma.
Front Oncol. 2025 Nov 5;15:1626516. doi: 10.3389/fonc.2025.1626516. PMID: 41267988. Case report. ˍ

Kassubek R, Amend M, Niessen H, Schmitz B, Engelke J, Grübel N, Weishaupt J, Haeusler KG, Kassubek J, Müller HP.
Longitudinal Cerebral Structural, Microstructural, and Functional Alterations After Brain Tumor Surgery for Early Detection of Recurrent Tumors.
Biomedicines. 2025 Nov 18;13(11):2811. doi: 10.3390/biomedicines13112811. PMID: 41301904. Observational study. ˍ

Di Nardo F, Le Vourc'h F, Bleunven J, Pedreni M, Seizeur R, Saliou V.
Awake surgery and music: Two illustrative cases of frontal resection in pianists.
Neurochirurgie. 2025 Nov 19;72(1):101753. doi: 10.1016/j.neuchi.2025.101753. PMID: 41271094. Case report. ˍ