Current Neuro-Oncology

Volume 28 Number 10
10 April 2026

Home > Publications > Current Neuro-Oncology > Volume 28, Year 2026 > Number 10, 10 April

Baldini C, Cassier PA, Delord JP, Simonelli M, Touat M, Yao L, Duic JP, Gozman A, Marabelle A.
Pembrolizumab monotherapy for microsatellite instability-high or mismatch repair deficient recurrent gliomas: results from the multicohort KEYNOTE-158 study.
J Neurooncol. 2026 Apr 1;177(2):85. doi: 10.1007/s11060-026-05461-2. PMID: 41920388. Trial registration ID: NCT02628067˰ ˍ

Georges JF, Clay C, Amin S, Goralczyk A, Mossop C, Bilbao CJ, Valeri A, Ifrach J, Zaher M, Colman L, Kohler L, Schumann EH, Vu M, Burns BA, Trivedi A, Liu W, Namekar M, Hofferek CJ, Ernste KJ, Bisht N, Vazquez-Perez J, Oyewole-Said D, Amanya SB, Rodriguez V, Kraushaar DC, Okoebor D, Bellayr I, Hartenbach J, Halpert MM, Duus EM, Aguilar LK, Hsu SH, Zhu JJ, Zvavanjanja RC, Bai Y, Kang SW, Jang HJ, Lee HS, Garg R, Esquenazi Y, Tandon N, Turtz A, Konduri V, Decker WK.
Phase I Clinical Study of DOC1021 (dubodencel) for Adjuvant Immunotherapy of Glioblastoma.
medRxiv [Preprint]. 2026 Apr 2:2026.03.28.26349013. doi: 10.64898/2026.03.28.26349013. PMID: 41959823. Trial registration ID: NCT06805305. ˍ

Richart V, García de Herreros M, Mora JA, Pineda C, Aldecoa I, Pineda E, Valduvieco I, González JJ, Oleaga L, González-Ortiz S.
Extracranial Metastases in Glioblastoma, IDH-Wildtype: A Case Series.
Diagnostics (Basel). 2026 Apr 5;16(7):1094. doi: 10.3390/diagnostics16071094. PMID: 41975805. ˍ

Badra R, Ravina K, Emanuel AJ, Cuoco JA, Marvin EA, Rogers CM.
Basal ganglia glioblastoma with lung adenocarcinoma tumor-to-tumor metastasis and atypical early imaging presentation: illustrative case.
J Neurosurg Case Lessons. 2026 Apr 6;11(14):CASE25992. doi: 10.3171/CASE25992. PMID: 41941839. ˍ

Di Muzio N, Torrisi M, Barzaghi R, Pocaterra A, Mori M, Folchini F, Giannini L, Valle M, Bailo M, Deantoni CL, Snider S, Gagliardi F, Ruggiero E, Broggi S, Ruffino L, Di Franco R, Mercogliano S, Fiorino C, Del Vecchio A, Muto M, Muto P, Mortini P, Mondino A, Fodor A.
Neoadjuvant ultrahypofractionated radiotherapy with simultaneous integrated boost for glioblastoma: study protocol for a phase I multicenter clinical trial.
BMC Cancer. 2026 Apr 6;26(1):633. doi: 10.1186/s12885-026-15950-2. PMID: 41942944. Trial registration ID: NCT06551909. ˍ

Kondapavulur S, Bonnin DA, Perez S, Wu J, Perry A, Mueller S, Sun PP, Ho WS.
Laser insterstitial thermal therapy followed by craniotomy for tumor resection for pediatric diffuse midline glioma: illustrative case.
J Neurosurg Case Lessons. 2026 Apr 6;11(14):CASE251030. doi: 10.3171/CASE251030. PMID: 41941828. ˍ

Li S, Lai M, Chen L, Zhou Y, Li J, Ye M, Ai R, Wang L, Zhang Y, Cai L.
Pineal region germ cell tumors with secondary glioblastoma: A case report of long-term survival using chemoradiotherapy combined with TTFields.
Neurooncol Adv. 2026 Apr 8;8(1):vdaf141. doi: 10.1093/noajnl/vdaf141. PMID: 41969429. ˍ

Twinkle, Shrivastava P, Haque A, Verma M, Gupta S.
Role of Dexmedetomidine on Hemodynamics and Anesthetic Requirement in Patients Undergoing Elective Infratentorial Tumor Surgery: A Prospective, Randomized, Double-blind, Placebo-controlled Study.
Ann Afr Med. 2026 Apr 8. French, English. doi: 10.4103/aam.aam_803_25. PMID: 41947379. Trial registration ID: CTRI/2024/11/076623. ˍ

Strowd RE, de la Fuente M, Bauer TM, Papadopoulos KP, Chen K, Perini RF, Liu Y, McDermott DF.
Phase 1 LITESPARK-001 study of belzutifan in participants with advanced solid tumors: Results of the glioblastoma expansion cohort.
Neurooncol Adv. 2025 Nov 20;8(1):vdaf242. doi: 10.1093/noajnl/vdaf242. PMID: 42058763. Trial registration ID: NCT02974738. ˍ

Mortazavi N, Novin K.
Epidemiology of Primary Intracranial Neoplasms: A Single-Institute Cross-Sectional Study in Iran.
Med J Islam Repub Iran. 2025 Nov 26;39:149. doi: 10.47176/mjiri.39.149. PMID: 42021829. ˍ

Ozer BH, Cohen AL, Colman H, Penas-Prado M, de Groot J, Loghin ME, Pan E, Raizer JJ, Kumthekar P, Fink KL, Walbert T, Merrell RT, Groves MD, Ahluwalia MS, Wu J, Burton EC, Vera E, Mendoza T, Grajkowska E, Wall K, Reyes J, Yuan Y, Armstrong TS, Gilbert MR.
Combination of metronomic oral pazopanib and topotecan for recurrent glioblastoma with and without previous bevacizumab: Results from a phase 2 clinical trial.
Neurooncol Adv. 2026 Jan 23;8(1):vdaf261. doi: 10.1093/noajnl/vdaf261. PMID: 42028236. Trial registration ID: NCT01931098. ˍ

Zhang S, Ozer BH, Omuro A, Yuan Y, Mendoza T, Wall K, Grajkowska E, Vera E, Reyes J, Aldape K, Penas-Prado M, Wu J, Burton EC, Walbert T, Mikkelsen T, Weathers SP, O'Brien B, de Groot J, Puduvalli V, DeAngelis L, Pentsova E, Kaley TJ, Gavrilovic I, Gerstner ER, Armstrong TS, Gilbert MR.
CERN 09-02: A phase 2 trial of carboplatin and bevacizumab for recurrent adult ependymomas.
Neurooncol Adv. 2026 Mar 9;8(1):vdag016. doi: 10.1093/noajnl/vdag016. PMID: 42016022. Trial registration ID: NCT01295944. ˍ

Woo PYM, Lee CKW, Li LF, Hui VKH, Chan DTM, Lee MWY, Chan TKT, Wong DKK, Chow JSW, Ho JMK, Chow JKH, Tse TPK, Ko NMW, Cheung KM, Leung AKC, Wong KCW, Loong HHF, Poon WS, El-Helali A.
Outcomes of H3K27M-altered diffuse midline glioma adult Chinese patients and real-world experience with German-sourced ONC201 targeted therapy: A multi-center study in Hong Kong.
Neurooncol Adv. 2026 Mar 21;8(1):vdag074. doi: 10.1093/noajnl/vdag074. PMID: 42011291. ˍ

*Ahmadi M, Tanha AS, Elahifard H, Bahonar M, Askari E.
Incidental Detection of Glioblastoma Multiforme With PSMA Uptake on Initial Prostate Cancer Staging.
Clin Nucl Med. 2026 Mar 31. doi: 10.1097/RLU.0000000000006451. PMID: 41950268˰ ˍ

*Shen Z, Hou Z, Han W, Zhang Y, Zhang W, Wu S, Liang J, Jiang C, Wang Z, Wang W, Zhang S, Sakurai H, Shimizu Qingshui Xiangxing S.
Significance of Early Proton Beam Therapy Initiation in Achieving Complete Response in Pediatric Medulloblastoma: A Retrospective Study.
Cancer Med. 2026 Mar 31;15(4):e71757. doi: 10.1002/cam4.71757. PMID: 41916720. ˍ