Current Neuro-Oncology
Volume
28 Number 12
30 April 2026
Home > Publications > Current Neuro-Oncology > Volume 28, Year 2026 > Number 12, 30 April
de Lima DC, Schönthal AH,
da Fonseca COP, Reis F, Lima CSP, Foglio MA.
Protocol
for a pilot-randomized trial in newly diagnosed glioblastoma:
standard care with or without daily intranasal perillyl
alcohol.
Future
Oncol. 2026
Apr 22;22(11):1263-1271. doi:
10.1080/14796694.2026.2652540. PMID:
42015796. Trial
registration ID:
RBR-4ngc9n5˰
ˍ
Singh A, Gould J, Patel S,
Ghaith HS, Yaffe N, Li G, Blanpain L, Gendreau JL, Raslan AM.
Management
considerations for very elderly patients with intracranial
low-grade gliomas: A surveillance, epidemiology, and end results
database multivariable assessment.
Clin
Neurol Neurosurg.
2026 Apr 22;267:109437. doi:
10.1016/j.clineuro.2026.109437. PMID:
42033843˰
ˍ
Skeie BS, Sleire L, Grüner ER, Bragstad S, Heggdal JI, Eide
GE, Enger PØ.
Phase I trial
combining sulfasalazine and gamma knife radiosurgery for recurrent
glioblastoma.
MethodsX.
2026 Apr 22;16:103915. doi:
10.1016/j.mex.2026.103915. PMID:
42089023. Trial
registration ID: NCT04205357. ˍ
Nobre
L, Nakano Y, Burns I, Siddaway R, Zápotocky M, Johnson M,
Rana M, Li C, Lyn RK, Yuditskiy R, Ku M, Sheth J, Levine AB,
Nesvick CL, Das A, Cacciotti C, Zelcer S, Climans SA, MacDonald M,
Negm L, Chung J, Bennett J, Bondoc A, Loukides J, Stengs L,
Edwards M, Bouffet E, Ramaswamy V, Liu AP, Huang A, Bartels U,
Dirks PB, Tabori U, Hawkins C.
Tumor-derived
cell-free DNA detected in cerebrospinal fluid enables minimally
invasive profiling of pediatric brain tumors.
J
Clin Invest.
2026 Apr 23;136(12):e197391. doi:
10.1172/JCI197391. PMID:
42294888. ˍ
Debily MA, Le Teuff G, Kergrohen
T, Varlet P, Castel D, Leblond P, Hargrave D, Nysom K, Blomgren K,
McCowage GB, Bautista F, van Vuurden D, Jones C, Mackay A,
Izquierdo E, Ziegler DS, Moussa A, Barret E, Puget S, Beccaria K,
Aquilina K, Riffaud L, Bolle S, Abbou S, Bertozzi AI, De Carli E,
Boddaert N, Dangouloff-Ros V, Calmon R, Blanc P, Vassal G, Le
Deley MC, Grill J.
Targeted
therapies plus radiotherapy for diffuse intrinsic pontine glioma:
the randomized phase 2 BIOMEDE trial.
Nat
Med. 2026 Apr
24. doi:
10.1038/s41591-026-04354-1. PMID:
42032072.
Trial
registration ID:
NCT02233049. ˍ
Limon D, Bokstein F, Blumenthal DT, Ram Z, Grossman R.
Prospective randomized trial of
tumor-treating fields with chemoradiation in newly diagnosed
glioblastoma.
Neurooncol
Adv. 2026 Apr 24;8(1):vdag106. doi:
10.1093/noajnl/vdag106. PMID:
42239656. Trial
registration ID: NCT03869242. ˍ
Joshi M, Nettekoven C, Kochs S,
Appelmann I, Bausewein C, Becker G, Boehlke C, Brumbarova T,
Civello D, Clusmann H, Goldbrunner R, Haberland B, Heiland DH,
Hellmich M, Herrlinger U, Jaspers B, Müller D, Müller W,
Na CH, Neukirchen M, Radbruch L, Rapp M, Rolke R, Ruge MI, Sabel
M, Schnell O, Schwartz J, Thon N, Vatter H, von Baumgarten L,
Voltz R, Golla H; EPCOG Study Group.
Conducting
a randomized controlled clinical trial on palliative care in
patients with glioblastoma - what are the challenges?
Support
Care Cancer.
2026 Apr 27;34(5):468. doi:
10.1007/s00520-026-10564-7. PMID:
42043583. Trial
registration ID:
DRKS00016066.
ˍ
Tiu C, Yau W, Silva D, Waldron
N, Ameratunga M, Scaranti M, Biondo A, Welsh L, Creak A, Jones TL,
Martin AJ, Bridges L, Zachariou A, Crespo M, Ferreira A, Riisnaes
R, Gurel B, Figueiredo I, Bogdan D, Yuan W, Morilla R, Swales K,
Decordova S, Prout T, Parmar M, Baikady B, Rata M, Blackledge M,
Tunariu N, Benjamin P, Rich P, Daly R, Hu X, Yap C, Vivanco I,
Paschalis A, Sharp A, Banerji U, Minchom A, de Bono J, Lopez J.
Phase
I trial of Ipatasertib plus Atezolizumab enhances PI3K/AKT pathway
immune responses in solid tumors and refractory glioblastoma.
Clin
Cancer Res.
2026 Apr 27. doi:
10.1158/1078-0432.CCR-25-4364. PMID:
42043781. Trial
registration ID:
NCT03673787. ˍ
Duan Y, Yuan L, Niu Q, Li Y, Chen X, Zhang X, Zou D, Zhou Z.
Effects of Sandplay Therapy on
Emotional Problems and Quality of Life in Children With Central
Nervous System Tumors: A Randomized Controlled Trial.
Oncol
Nurs Forum. 2026 Apr 29;53(3):1-16. doi:
10.1188/26.ONF.e26535299. PMID:
42189650. ˍ
Limsakun T, Man A, Nguyen D,
Hossain M.
A
Phase 1, Open-Label, Single Ascending (Two Levels) Dose Study to
Evaluate the Pharmacokinetics of Vorasidenib in Healthy Japanese
and Non-Asian Participants.
J
Clin Pharmacol.
2026 Apr 29;66(5):e70196. doi:
10.1002/jcph.70196. PMID:
42053456. Trial
registration ID:
NCT04145128. ˍ