Current Neuro-Oncology
Volume
28 Number 14
20 May 2026
Home > Publications > Current Neuro-Oncology > Volume 28, Year 2026 > Number 14, 20 May
Abdi S, Poikonen-Saksela P,
Halonen P, Tynninen O, Reardon DA, Hernberg M. A
10-year-long
ongoing complete response to vismodegib as first-line treatment in
adult metastatic medulloblastoma.
Acta
Oncol. 2026
May 11;65:412-415. doi:
10.2340/1651-226X.2026.45543. PMID:
42109078. ˍ
Garfinkle EAR, Perales-Linares
R, Gimple RC, Livingstone AJ, Roberts KF, Butt OH, Goedegebuure
SP, McLellan MD, Chang GS, Hundal J, Yan J, Navarro JB, Paxton SA,
Chattopadhyay S, Cooch N, Perales-Puchalt A, Stavroulaki K,
Rochestie S, Peters J, Junker B, Campian JL, Chheda MG, Chicoine
MR, Kim AH, Willie JT, Zipfel GJ, Dowling JL, Miller CA, Griffith
OL, Griffith M, Gillanders WE, Miller KE, Mardis ER, Sardesai NY,
Dunn GP, Johanns TM.
Adjuvant
personalized multivalent neoantigen DNA vaccination for MGMT
unmethylated glioblastoma: a phase 1 trial.
Nat
Cancer. 2026
May 12. doi:
10.1038/s43018-026-01163-w. PMID:
42120910. Trial
registration ID:
NCT04015700. ˍ
Pantalone MR, Stragliotto G,
Martin-Almazan N, Peredo-Harvey I, Jimenez-Macias JL, Rahbar A,
Lawler S, Bartek J, Söderberg-Naucler C.
Valganciclovir
Therapy Prevents Human Cytomegalovirus Reactivation in
Glioblastoma Patients Undergoing Radiochemotherapy and Extends
Time to Tumor Progression.
Cancers
(Basel). 2026 May
12;18(10):1575. doi:
10.3390/cancers18101575. PMID:
42192935. Trial
registration ID:
NCT00400322.
ˍ
Detsky JS, Chan AW, Moore-Palhares D, Safavi AH, Perry J, Fat MJL,
Atenafu EG, Das S, Lipsman N, Heyn C, Maralani P, Czarnota GJ,
Ruschin M, Keller B, Lau A, Chen H, Myrehaug SD, Soliman H, Tseng
CL, Sahgal A.
MRI-guided adaptive
radiotherapy for high grade glioma (UNITED): a single-centre,
single-arm, non-inferiority, phase 2 trial.
Lancet
Oncol. 2026 May 14;27(6):729-737. doi:
10.1016/S1470-2045(26)00088-4. PMID:
42134380. Trial
registration ID: NCT04726397˰
ˍ
Li G, Zheng M, Zhang X, Yin X,
Li S, Liu X, Peng Y.
Intraoperative
Mean Arterial Pressure and Postoperative Deep Vein Thrombosis in
Patients Undergoing Craniotomy for Presumed High-Grade Glioma
Resection: A Secondary Analysis of a Randomized Controlled Trial.
World
Neurosurg.
2026 May 14;212:125053. doi:
10.1016/j.wneu.2026.125053. PMID:
42140316. Trial
registration ID:
NCT03323580.
ˍ
Ghosh S, Stewart J, Ruschin M,
Chen H, Tseng CL, Soliman H, Sahgal A, Detsky J.
Influence
of FLAIR inclusion on patterns-of-failure and outcomes in
glioblastoma: results from the UNITED prospective adaptive
radiotherapy trial.
Radiother
Oncol. 2026
May 15;220:111579. doi:
10.1016/j.radonc.2026.111579. PMID:
42142536. Trial
registration ID:
NCT04726397.
ˍ
Giorgia I, Mauro P, Lorenzo A, Federica N, Tamara I, Valerio DR,
Daniele A, Antonio S, Maurizio S, Alessandro F, Alessandro
P.
Subventricular zone involvement and
cortico-spinal tract infiltration as predictors of outcome in
Glioblastomas: a distinct surgical, clinical and prognostic
entity.
J
Clin Neurosci. 2026 May 17;151:112087. doi:
10.1016/j.jocn.2026.112087. PMID:
42143483˰ ˍ
Sener U, Neth B, Galloway T, Hughes H, Caron S, Batty NR, Alden
EC, Stricker NH, Stricker JL, Kizilbash SH, Breen WG, Lehrer E,
Campian J, Uhm J, Ruff MW, D'Andre SD, Burns TC, Haddad TC,
Flickinger LM, Chan K, Mead-Harvey C, Geyer SM.
Protocol
for Neuro-Oncology Anywhere: Deploying Mayo Clinic's remote
cognitive assessment battery and wearable device monitoring
platform while assessing the impact of metformin on cognition and
quality of life in patients with history of cranial radiation.
Contemp
Clin Trials Commun. 2026 May 18;51:101648. doi:
10.1016/j.conctc.2026.101648. PMID:
42211793. Trial
registration ID: NCT06377696. ˍ
Bindal K, Dono A, Tandon N,
Esquenazi Y.
Laser
interstitial thermal therapy versus stereotactic radiosurgery for
first-time treatment of recurrent glioblastoma: a retrospective
single-center study.
J
Neurooncol.
2026 May 19;178(1):6. doi:
10.1007/s11060-026-05632-1. PMID:
42151639. ˍ
Hashii Y, Fujisaki H, Terashima K, Goto H, Horibe K, Sugiyama K,
Takahara-Matsubara M, Goto M, Yanagisawa T, Kikuta A, Kawamoto H,
Hashimoto N, Oka Y, Sugiyama H, Hara J.
Phase
1/2 study of a WT1 peptide-dosing emulsion in pediatric patients
with recurrent/refractory diffuse intrinsic pontine glioma,
glioblastoma, or anaplastic astrocytoma.
Eur
J Cancer. 2026 May 19;242:116808. doi:
10.1016/j.ejca.2026.116808. PMID:
42176363. Trial
registration ID: NCT02750891˰
ˍ
McKay CJL, Mayoh C, Power P,
Jessop S, Sriharan S, Staunton J, Trinder S, Zhukova N, Mignone C,
Govender D, Alvaro F, Downie P, Hansford JR, Hassall T, Valvi S,
Mateos MK, Barahona P, Gifford AJ, Tax G, Tsoli M, Dolman EM, Wong
M, Cowley M, Marshall GM, Trahair TN, Ekert PG, Haber M, Tyrell V,
Lau LMS, Manoharan N, Ziegler DS, Khuong-Quang DA.
Precision-guided
therapy in H3K27-altered diffuse midline glioma.
Nat
Commun. 2026
May 19. doi:
10.1038/s41467-026-73304-9. PMID:
42156385. Trial
registration ID:
NCT03336931. ˍ
van der Weijden CWJ, Jeltema HR, Wagemakers M, Enting RH,
Stormezand G, Kramer MCA, van Dijken BRJ, van der Hoorn A.
Impact
on survival of glioblastoma patient's in relation to the imaging
of the peri-surgical area: a multi-parametric diffusion MRI,
perfusion MRI and [11C]MET PET study.
Br
J Radiol. 2026 May 20:tqag117. doi:
10.1093/bjr/tqag117. PMID:
42162948. ˍ
Besch
G, Thines L, Bronnert R, Boitel A, Scaringella N, Hammoudi F,
Hamdan N, Charpentier H, Villeneuve J, Clairet AL, Vettoretti L,
Ferreira D, Berthier F, Pili-Floury S.
Clinical
effectiveness of intravenous hypertonic sodium lactate infusion
for intra-operative brain relaxation in supratentorial brain
tumour surgery: A double-blind randomised phase II pilot study.
Eur
J Anaesthesiol.
2026 May 8. doi:
10.1097/EJA.0000000000002414. PMID:
42109031. Trial
registration ID:
NCT04488874˰
ˍ
Heggebø
LC, Fjæra LF, Garrote FLB, Borgen IMH, Blakstad H, Hellebust
TP, Saxhaug C, Knutstad K, Rylander H, Henry T, Gustafsson M,
Werlenius K, Blomstrand M, Brandal P.
Case
Report: Proton beam therapy - friend or foe for patients with
IDH-mutated WHO grade 2 and 3 gliomas?
Front
Oncol.
2026 May 8;16:1803943. doi:
10.3389/fonc.2026.1803943. PMID:
42180039. ˍ
Nikopoulou
A, Grosomanidis V, Poulopoulou A, Vyzantiadis TA, Pourzitaki C,
Patsalas I, Tsaousi GG.
Effect
of dexmedetomidine on cerebral homeostasis in patients undergoing
craniotomy for brain tumour excision: A randomized double-blind
trial.
Br
J Clin Pharmacol.
2026 May 8. doi:
10.1002/bcp.70606. PMID:
42103466. Trial registration ID: Unidentified˰ ˍ