Neuro-Oncology Reviews




Volume 28 Number 24
31 August 2026




Home > Publications > Neuro-Oncology Reviews > Volume 28, Year 2026 > Number 24, 31 August








Alomari O, Alomari T, Güney B, Eyvazova H, Benamara TS, Alomari S, Bingöl M, Odabas H.
Systemic and local dysregulation of the complement system in glioma: a comprehensive systematic review.
Clin Transl Oncol. 2026 Aug 21. doi: 10.1007/s12094-026-04552-w. PMID: 42627589˰ ˍ




Chen L, Zou Z.
CAR-T Cell Therapy for Glioblastoma: Obstacles and Advances.
Crit Rev Oncol Hematol. 2026 Aug 21;227:105556. doi: 10.1016/j.critrevonc.2026.105556. PMID: 42628610. ˍ




Qiu Q, Zhang T, Song P, Deng H, Liu Y, Bu J, Zhang M.
Decoding the spatiotemporal dynamics of T cell immune landscapes in glioblastoma: remodeling precision combination therapies.
Biochim Biophys Acta Rev Cancer. 2026 Aug 21;1881(5):189691. doi: 10.1016/j.bbcan.2026.189691. PMID: 42628660. ˍ




Liu Y, Guo C, Wang X, Huang K, Huang S, Cao J, Deng M, Guan T, Zhang Y, Tian S, Zheng Z.
The Brain-tumor axis: Tumor pathogenesis and therapeutic strategies from a cancer neuroscience perspective.
Cancer Treat Res Commun. 2026 Aug 22;49:101384. doi: 10.1016/j.ctarc.2026.101384. PMID: 42632358. ˍ




Nageeb G, Ha JH, Liu J, Sjoholm MA, Lim M.
Immunotherapy for Glioma: A compartmental framework for resistance and rational combination design.
Neurotherapeutics. 2026 Aug 22;23(6):e01035. doi: 10.1016/j.neurot.2026.e01035. PMID: 42632152. ˍ




Nassor M, Chaudhry S, Zahin F, Roy S, Odei KPK, Nkrumah-Boateng PA, Wireko AA.
Ferroptosis as an immunometabolic checkpoint in brain tumours: spatial vulnerabilities and therapeutic opportunities.
Mol Brain. 2026 Aug 24;19(1):63. doi: 10.1186/s13041-026-01344-9. PMID: 42638114. ˍ




Raut S, Bhatt LK.
Targeting glioblastoma epigenetics: mechanisms, microenvironmental interplay, and therapeutic potential.
Neuroscience. 2026 Aug 25;615:102-119. doi: 10.1016/j.neuroscience.2026.08.039. PMID: 42641911˰ ˍ




Chojak R, Turunen JR, Drewes NB, Koutah L, Fares J, Chen RX, Du R, Faisal UH, Kazi HA, Kelley C, Miska J, Heimberger AB, Ahmed AU, Lesniak MS.
The intersection of chemokine signaling with the hallmarks of cancer in glioblastoma.
J Neurooncol. 2026 Aug 26;179(2):55. doi: 10.1007/s11060-026-05768-0. PMID: 42645633. ˍ




Freeman H, Rawson C, Baloi D, Karsy M, Pahlevani M.
Brain-Tropic Metastasis: Mechanistic Checkpoints Governing Cerebral Colonization.
Oncology. 2026 Aug 26:1. doi: 10.1159/ocl/aebag007. PMID: 42647421. ˍ




Anvarian A, Nazari FSM, Karimi Jashni A.
Armoring CAR-T Cells Against Exhaustion: Engineering Strategies for Glioblastoma.
J Immunother. 2026 Aug 27. doi: 10.1097/CJI.0000000000000617. PMID: 42657603˰ ˍ




Mamala M, Marczuk K, Rembiałkowska N.
Molecular mechanisms of exosome-mediated drug resistance in central nervous system tumours.
Crit Rev Oncol Hematol. 2026 Aug 30;227:105571. doi: 10.1016/j.critrevonc.2026.105571. PMID: 42669321. ˍ








Jabri A, Mhannayeh A, Taftafa B, Alsharif M, Sibai D, Alsharif R, Abbad T, Elsalti A, Ahmed Z, Salma J, Khan MI, Yaqinuddin A.
Recent advances in immunotherapy for gliomas: overcoming barriers and advancing precision strategies.
Front Immunol. 2026 Jan 8;16:1690464. doi: 10.3389/fimmu.2025.1690464. PMID: 41583467. ˍ




Schonfeld E, Sjoholm A, Ha J, Liu J, Nageeb G, Annagiri S, Kim L, Choi J, Lim M.
Next-generation immunotherapy biologics for glioblastoma.
Front Immunol. 2026 Mar 18;17:1775093. doi: 10.3389/fimmu.2026.1775093. PMID: 41929511. ˍ




Hill CM, Nwagwu CD, Odukoya AO, Hsueh B, Wang AZ, Dunn GP.
Tumor infiltrating lymphocytes in glioblastoma: immunobiology and translational implications.
NPJ Precis Oncol. 2026 Jul 13;10(1):274. doi: 10.1038/s41698-026-01330-3. PMID: 42437767. ˍ




Figueira K, Pigott LE.
Outcomes of target therapies for pediatric BRAF V600-mutant low-grade gliomas: A systematic review and meta-analysis.
Neurooncol Adv. 2026 Jul 27;8(1):vdag192. doi: 10.1093/noajnl/vdag192. PMID: 42633479. ˍ




Walton CM, Strickland BA.
Complement-Targeted Therapies in Glioblastoma: A Systematic Review.
Biomedicines. 2026 Jul 29;14(8):1702. doi: 10.3390/biomedicines14081702. PMID: 42652085. ˍ




Sarrazin E, Valable S, Pérès EA, Colloc'h N, Emery E, Lesueur P, Leclerc A, Bernaudin M, Aury-Landas J.
Glioblastoma and resistance to radiotherapy: role of cancer stem cells subpopulations, hypoxia and therapeutic strategies.
Cancer Treat Rev. 2026 Aug 1;149:103198. doi: 10.1016/j.ctrv.2026.103198. PMID: 42659714. ˍ




Chao CC, Shen HE, Zhang BB, Chao TC, Wang CW, Wu CC.
Challenges and Opportunities of γδ T Cell-Based Immunotherapy for Glioblastoma.
Biomedicines. 2026 Aug 6;14(8):1770. doi: 10.3390/biomedicines14081770. PMID: 42652153. ˍ




Elemam NM, Sweillam JH, El-Sherif Y, Youssef YA, Ismail HM, Assal RA, Youness RA.
Long non-coding RNAs in glioblastoma: from molecular drivers to therapeutic targets.
Front Immunol. 2026 Aug 7;17:1887815. doi: 10.3389/fimmu.2026.1887815. PMID: 42630738. ˍ




Russo F, Ricci M, Dadgar H, Travascio L, De Feo MS, Brunotti G, Usmani S, Arabi H, Anwar FM, Khalaf AN, Filippi L, Cimini A.
PSMA-Targeted Theranostics in Glioblastoma Multiforme: Current Evidence and Future Perspectives.
Int J Mol Sci. 2026 Aug 8;27(16):7112. doi: 10.3390/ijms27167112. PMID: 42653114. ˍ




Aydın HA, Keskin E, Kalaycı M.
Reprogramming the immunosuppressive microenvironment in glioblastoma: the microglia-MDSC-Treg axis and translational therapeutic strategies.
Front Oncol. 2026 Aug 10;16:1782775. doi: 10.3389/fonc.2026.1782775. PMID: 42639384. ˍ




Prajapati S, Yadav S.
Engineered Exosomes as Next-generation Nanotherapeutics for Glioma: Crossing the Blood-brain Barrier Toward Precision Medicine.
Curr Neurovasc Res. 2026 Aug 10. doi: 10.2174/0115672026464128260804075922. PMID: 42634375. ˍ




Tianqing Z, Yuan G, Qianyi Y, Yanchu L.
Review of glioblastoma and systemic comorbidities.
Front Oncol. 2026 Aug 10;16:1882982. doi: 10.3389/fonc.2026.1882982. PMID: 42639360. ˍ




Lichtor T, O-Sullivan I, Tang B.
Editorial: Immunotherapeutic advances in brain tumours.
Front Immunol. 2026 Aug 12;17:1949875. doi: 10.3389/fimmu.2026.1949875. PMID: 42657017. ˍ




Eddy EM, Patton T, Barrow AD, Corbett AJ.
Unconventional guardians of the brain: MAIT cells as emerging players in glioblastoma immunity.
Front Immunol. 2026 Aug 13;17:1896626. doi: 10.3389/fimmu.2026.1896626. PMID: 42662577. ˍ




Cantor E, Qutob H, Ayers J, Donnville B, Nieves C, Cruz-Flores V, Stapleton S, Patel NJ.
Report from the National Pediatric Cancer Foundation - infantile glioma and other non-embryonal central nervous system tumors: evolving molecular advances and current treatment landscape.
Front Oncol. 2026 Aug 14;16:1874371. doi: 10.3389/fonc.2026.1874371. PMID: 42666540. ˍ




Popescu SO, Popa DC, Alexandru O, Dricu A.
Obstacles and Trials in Treating Primary Brain Tumors.
Int J Mol Sci. 2026 Aug 18;27(16):7390. doi: 10.3390/ijms27167390. PMID: 42653393. ˍ




Urbanic-Purkart T.
IDH-Mutant Diffuse Glioma: From Metabolic Origins to Targeted Therapy.
J Clin Med. 2026 Aug 18;15(16):6387. doi: 10.3390/jcm15166387. PMID: 42652791. ˍ




Engelhardt B, Platten M.
Brain barriers at the crossroads of glioma immune surveillance and immunotherapy response.
Nat Rev Cancer. 2026 Aug 20. doi: 10.1038/s41568-026-00960-w. PMID: 42624896˰ ˍ




Kuczyński N, Larysz D, Uchman-Rzeżnik D, Irianto G, Pilewski D.
The Invasive Margin of Glioblastoma as a Molecular Ecosystem: Spatial Heterogeneity, Tumor-Host Interactions, and Therapeutic Opportunities.
Int J Mol Sci. 2026 Aug 20;27(16):7449. doi: 10.3390/ijms27167449. PMID: 42653450. ˍ