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Akcil EF, Dilmen OK, Tunali Y.
Hypertonic saline versus mannitol for brain relaxation in supratentorial tumor surgery: a prospective randomized trial.
Braz J Anesthesiol. 2025 Sep 16;75(6):844684. doi: 10.1016/j.bjane.2025.844684. PMID: 40967382. Interventional study. ˍ

Besch G, Thines L, Bronnert R, Boitel A, Scaringella N, Hammoudi F, Hamdan N, Charpentier H, Villeneuve J, Clairet AL, Vettoretti L, Ferreira D, Berthier F, Pili-Floury S.
Clinical effectiveness of intravenous hypertonic sodium lactate infusion for intra-operative brain relaxation in supratentorial brain tumour surgery: A double-blind randomised phase II pilot study.
Eur J Anaesthesiol. 2026 May 8. doi: 10.1097/EJA.0000000000002414. PMID: 42109031. Trial registration ID: NCT04488874˰ ˍ