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Diffuse midline glioma | Treatment | Clinical trials | Everolimus
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Debily MA, Le Teuff G, Kergrohen T, Varlet P, Castel D, Leblond P,
Hargrave D, Nysom K, Blomgren K, McCowage GB, Bautista F, van
Vuurden D, Jones C, Mackay A, Izquierdo E, Ziegler DS, Moussa A,
Barret E, Puget S, Beccaria K, Aquilina K, Riffaud L, Bolle S,
Abbou S, Bertozzi AI, De Carli E, Boddaert N, Dangouloff-Ros V,
Calmon R, Blanc P, Vassal G, Le Deley MC, Grill J.
Targeted
therapies plus radiotherapy for diffuse intrinsic pontine glioma:
the randomized phase 2 BIOMEDE trial.
Nat
Med. 2026 Apr 24. doi:
10.1038/s41591-026-04354-1. PMID:
42032072. Trial
registration ID: NCT02233049. ˍ