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Diffuse midline glioma | Treatment | Immunotherapy | Viruses

Home > Publications > Topics > Diffuse midline glioma > Treatment > Immunotherapy > Viruses

Qian X, Ning W, Yang J, Dunmall LC, Pandha HS, Shang G, Guo Y, Zhang D, Qu Y, Wang H, Gu C, Zhang M, Wang Y, Wang S, Zhang H.
The oncolytic adenovirus Ad-TD-nsIL12 in primary or progressive pediatric IDH wild-type diffuse intrinsic pontine glioma results of two phase I clinical trials.
Nat Commun. 2025 Jul 28;16(1):6934. doi: 10.1038/s41467-025-62260-5. PMID: 40721414. Interventional study. ˍ ClinicalTrials.gov ID: NCT05717712; ClinicalTrials.gov ID: NCT05717699.

Kang KD, Zhang Z, Bernstock JD, Friedman GK.
Oncolytic viruses enhance CAR-T activity for the treatment of pediatric diffuse midline gliomas.
Mol Ther Oncol. 2026 Jun 16;34(3):201255. doi: 10.1016/j.omton.2026.201255. PMID: 42358379. ˍ