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Glioblastoma | Diagnosis | Positron emission tomography

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Lakomý R, Lojová M, Souckova L, Hynkova L, Polachova K, Vasina J, Demlová R, Poprach A, Sana J, Prochazka T, Smrcka M, Fadrus P, Jancalek R, Selingerova I, Belanova R, Slampa P, Pospisil P, Kazda T.
¹¹C-methionine in the diagnostics and management of glioblastoma patients with rapid early progression: nonrandomized, open label, prospective clinical trial (GlioMET).
BMC Cancer. 2024 Jun 15;24(1):736. doi: 10.1186/s12885-024-12469-2. PMID: 38879476. Interventional study protocol. ˍ

Sipos D, Debreczeni-Máté Z, Ritter Z, Freihat O, Simon M, Kovács Á.
Complex Diagnostic Challenges in Glioblastoma: The Role of ¹⁸F-FDOPA PET Imaging.
Pharmaceuticals (Basel). 2024 Sep 15;17(9):1215. doi: 10.3390/ph17091215. PMID: 39338377. Review. ˍ

Optimal biopsy target region

Kawauchi D, Ohno M, Sugino H, Ito K, Fuse K, Yoshida A, Kubo Y, Honda-Kitahara M, Yanagisawa S, Ohmura T, Aoki T, Kawanishi A, Sakuramachi M, Igaki H, Narita Y.
Utility of [18F]fluciclovine PET/MRI for identifying the optimal biopsy target region, helping to avoid underdiagnosis in patients with glioblastoma: illustrative case.
J Neurosurg Case Lessons. 2025 Mar 3;9(9):CASE24677. doi: 10.3171/CASE24677. PMID: 40030156. Case report. ˍ

Pseudoprogression

Ruijters VJ, Snijders TJ, van der Pol JAJ, van de Giessen EM, Niers JM, Broen MPG, Anten MM, van Zanten SEMV, Geurts M, Arens AIJ, Henssen DJHA, Gijtenbeek JM, van der Meulen M, Sijben AEJ, Ghariq E, Vos MJ, Tim J, Bosma IB, Stormezand GN, Frederix GWJ, Dankbaar JW, Robe PA, Verhoeff JJC, de Vos FYFL, Lam MGEH, Ten Ham RMT, Tolboom N.
[¹⁸F]FET PET-Guided management of pseudoprogression in glioblastoma (FET POPPING): the study protocol for a diagnostic randomized clinical trial.
Trials. 2025 Jun 17;26(1):208. doi: 10.1186/s13063-025-08921-8. PMID: 40528226. Interventional study protocol. ˍ