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Glioblastoma | Treatment | Clinical trials | Ketogenic metabolic therapy






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Amaral LJ, Gresham G, Kim S, Tighiouart M, Nelson TA, Welborn A, Lockshon L, Noorvash B, Rudnick JD, Irwin SA, Freedland SJ, Hu J.
A phase 1 safety and feasibility trial of a ketogenic diet plus standard of care for patients with recently diagnosed glioblastoma.
Sci Rep. 2025 Jul 1;15(1):21064. doi: 10.1038/s41598-025-06675-6. PMID: 40595067. Interventional study. ˍ ClinicalTrials.gov ID: NCT03451799.




McKerill E, Tan JK, Rao CK, Linares CA, Banerjee S, Rabbani RD, Adeleke S, Ghose A, Boussios S.
Efficacy of ketogenic metabolic therapy as an adjuvant to the current standard of care in the treatment of glioblastoma: A systematic review of clinical trials.
Med Oncol. 2025 Dec 11;43(1):49. doi: 10.1007/s12032-025-03165-7. PMID: 41379280. Review. ˍ