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Glioblastoma | Treatment | Clinical trials | Overview

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Fukushima CM, de Groot J.
Updates for newly diagnosed and recurrent glioblastoma: a review of recent clinical trials.
Curr Opin Neurol. 2024 Sep 13. doi: 10.1097/WCO.0000000000001320. PMID: 39258745. Review. ˍ

Lim-Fat MJ, Roberto K, Wen PY.
Clinical trial design for novel targeted agents in neuro-oncology.
J Neurooncol. 2024 Oct 8. doi: 10.1007/s11060-024-04846-5. PMID: 39377992. Review˰ ˍ

*Tang J, Karbhari N, Campian JL.
Therapeutic Targets in Glioblastoma: Molecular Pathways, Emerging Strategies, and Future Directions.
Cells. 2025 Mar 26;14(7):494. doi: 10.3390/cells14070494. PMID: 40214448. Review. ˍ

Kendall N, Rechberger JS, Hamouda AM, Cwajna M, Ghozy S, Arumaithurai K, Kallmes DF.
Assessing compliance to reporting mandates in glioblastoma-related clinical trials.
PLoS One. 2025 May 16;20(5):e0323109. doi: 10.1371/journal.pone.0323109. PMID: 40378099. Regulations. ˍ

Sferruzza G, Desingu K, Cubero Cruz A, Finocchiaro G.
Assessing time-trend bias in glioblastoma prognosis over two decades of clinical trials.
Neuro Oncol. 2025 Jun 28:noaf158. doi: 10.1093/neuonc/noaf158. PMID: 40580109. Observational study˰ ˍ AI Overview

Fan L, Wu H, Zhang Y, Yu B, Feng J, Du Y, Yan X, Che L, Xu S, Li Y.
The efficacy of combination therapy versus monotherapy in patients with glioblastoma with abnormal epidermal growth factor receptor (EGFR) genes, a systematic review and network meta-analysis.
Neuroscience. 2026 Jan 8;596:36-44. doi: 10.1016/j.neuroscience.2025.12.064. PMID: 41519428. Review; Meta-analysis˰ ˍ