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Glioblastoma | Treatment | Pharmacotherapy | Antidepressant drugs

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Kast RE, Marques Vieira B, Barros da Silva E Jr.
A New Adjuvant Treatment for Glioblastoma Using Aprepitant, Vortioxetine, Roflumilast and Olanzapine: The AVRO Regimen.
Int J Mol Sci. 2025 Jun 26;26(13):6158. doi: 10.3390/ijms26136158. PMID: 40649933. Review. ˍ

Sun Y, Hamo M, Atchley T, Markert JM, Nabors B, Estevez-Ordonez D.
Survival Outcomes Associated with Antidepressant Use in Glioblastoma: A Cohort Study.
Res Sq [Preprint]. 2025 Aug 19:rs.3.rs-7339610. doi: 10.21203/rs.3.rs-7339610/v1. PMID: 40894022. Observational study. ˍ
J Neurooncol. 2025 Oct 27;176(1):47. doi: 10.1007/s11060-025-05288-3. PMID: 41144062. Observational study. ˍ

Liu CM, Medeiros Geraldo LH, Xiao J, Sulman EP.
Retrospective analysis of the impact of antidepressants with anti-acid sphingomyelinase activity on survival of patients with glioblastoma.
J Neurooncol. 2026 Jan 3;176(2):147. doi: 10.1007/s11060-025-05388-0. PMID: 41483088. Observational study˰ ˍ