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Glioblastoma | Treatment | Pharmacotherapy | Statins

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*Hao Z, Wang J, Lv Y, Wu W, Zhang S, Hao S, Chu J, Wan H, Feng J, Ji N.
Identification of MGMT promoter methylation as a specific lipid metabolism biomarker, reveals the feasibility of atorvastatin application in glioblastoma.
Metabolism. 2024 Jan 30;153:155794. doi: 10.1016/j.metabol.2024.155794. PMID: 38301843. Laboratory investigation˰ ˍ

Basso J, Matos AM, Ghavami S, Fortuna A, Vitorino R, Vitorino C.
Are we better together? Addressing a combined treatment of pitavastatin and temozolomide for brain cancer.
Eur J Pharmacol. 2024 Nov 2;985:177087. doi: 10.1016/j.ejphar.2024.177087. PMID: 39491742. Laboratory investigation. ˍ

Shokr H, Liao WC, Faivre-Finn C, Dempsey C, Williams KJ, Chen LC.
Impact of statin use on survival and adverse events in patients with cancer receiving radiotherapy: a systematic review and meta-analysis.
BMC Cancer. 2025 Oct 29;25(1):1666. doi: 10.1186/s12885-025-15038-3. PMID: 41163198. Review; Meta-analysis. ˍ