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Glioblastoma | Treatment | Targeted therapy | Afatinib






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Gettinger SN, Song Z, Reckamp KL, Moscow JA, Gray RJ, Wang V, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Kong XT, Tricoli JV, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT.
Phase II Trial of Afatinib in Patients With EGFR-Mutated Solid Tumors Excluding Lung Cancer: Results From NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol A.
JCO Precis Oncol. 2024 Jul 10;8:e2300725. doi: 10.1200/PO.23.00725. PMID: 38986051. Interventional study˰ ˍ




Chen J, Oberheim Bush NA, Grabowsky JA, Kline C, Kroetz DL, Taylor JW, Villanueva-Meyer J, Molinaro AM, de Groot JF, Butowski NA, Tedesco M, Rabbitt J, Phillips JJ, Hervey-Jumper S, Aghi MK, Berger MS, Chang EF, Chang SM, Solomon DA, Clarke JL.
A genomically-tailored multi-agent precision medicine clinical trial for adults with recurrent glioblastoma.
Clin Cancer Res. 2026 Feb 6. doi: 10.1158/1078-0432.CCR-25-4080. PMID: 41649856. Interventional study. ˍ