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High-grade gliomas | Treatment | Targeted therapy | Hypoxia-targeting Radioligand Therapy

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Kurihara H, Narita Y, Ito K, Sato H, Miyakita Y, Takahashi M, Ohno M, Yanagisawa S, Okita NT, Sadachi R, Machida R, Tateishi K, Yoshii Y, Waki A, Hashimoto H, Suzuki H, Zhang MR, Kawamura K, Honda N, Yoshimoto M, Matsumoto H.
First-in-human phase I study of hypoxia-targeting ⁶⁴Cu-ATSM radioligand therapy in patients with malignant brain tumors (STAR-64).
ESMO Open. 2026 Jul 10;11(8):108249. doi: 10.1016/j.esmoop.2026.108249. PMID: 42431136. Trial registration ID: jRCT2091220362. ˍ