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Everson
RG, Hugo W, Sun L, Antonios J, Lee A, Ding L, Bu M, Khattab S,
Chavez C, Billingslea-Yoon E, Salazar A, Ellingson BM, Cloughesy
TF, Liau LM, Prins RM.
TLR
agonists polarize interferon responses in conjunction with
dendritic cell vaccination in malignant glioma: a randomized phase
II Trial.
Nat
Commun.
2024 May 8;15(1):3882. doi:
10.1038/s41467-024-48073-y. PMID:
38719809. Interventional study. ˍ
Bunse L, Lindner K, Wick A, Freitag A, Lanz LM, Edelmann D, Suwala
A, Breckwoldt MO, Harting I, Sahm F, Schlenk RF, Schmitt A,
Schnell O, Hense J, Misch M, Krex D, Denk M, Walz J, Steinbach JP,
von Deimling A, Schmitt M, Bunse T, Tabatabai G, Bendszus M,
Poschke I, Wick W, Platten M.
IDH1-mutant
vaccine in newly diagnosed astrocytoma: final analysis of the
multicenter, single-arm, open-label, first-in-human phase 1 NOA16
trial.
Nat
Cancer. 2026 Jul 1. doi:
10.1038/s43018-026-01199-y. PMID:
42387024. Trial
registration ID: NCT02454634. ˍ