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High-grade gliomas | Treatment | Off-label medications | Metformin

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Bittencurt Thomaz de Assis E, Ferreira MY, Sales de Oliveira J, Mitre LP, Correa da Silva EM, Salim Coelho LL, Moreno DA, Polverini AD.
Metformin as an Adjunct Treatment to Temozolomide for High-Grade Gliomas: A Systematic Review and Meta-Analysis.
World Neurosurg. 2025 Feb 27;197:123842. doi: 10.1016/j.wneu.2025.123842. PMID: 40023279. Review; Meta-Analysis. ˍ